Shankar Siva

Summary

Affiliation: Peter MacCallum Cancer Centre
Country: Australia

Publications

  1. doi request reprint Abscopal effects of radiation therapy: a clinical review for the radiobiologist
    Shankar Siva
    Division of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, Vic, Australia Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Vic, Australia Electronic address
    Cancer Lett 356:82-90. 2015
  2. pmc A prospective observational study of Gallium-68 ventilation and perfusion PET/CT during and after radiotherapy in patients with non-small cell lung cancer
    Shankar Siva
    Division of Radiation Oncology and Cancer Imaging, St Andrews Place, East Melbourne 3002, Australia
    BMC Cancer 14:740. 2014
  3. pmc An analysis of respiratory induced kidney motion on four-dimensional computed tomography and its implications for stereotactic kidney radiotherapy
    Shankar Siva
    Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia
    Radiat Oncol 8:248. 2013
  4. doi request reprint 18F-FDG PET provides high-impact and powerful prognostic stratification in the staging of Merkel cell carcinoma: a 15-year institutional experience
    Shankar Siva
    Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia
    J Nucl Med 54:1223-9. 2013
  5. doi request reprint A systematic review of stereotactic radiotherapy ablation for primary renal cell carcinoma
    Shankar Siva
    Division of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Centre, Vic, Australia
    BJU Int 110:E737-43. 2012
  6. doi request reprint Analysis of the impact of chest wall constraints on eligibility for a randomized trial of stereotactic body radiotherapy of peripheral stage I non-small cell lung cancer
    Shankar Siva
    Department of Radiation Oncology, University of Melbourne, Melbourne, Victoria, Australia
    J Med Imaging Radiat Oncol 56:654-60. 2012
  7. doi request reprint Implementation of a lung radiosurgery program: technical considerations and quality assurance in an Australian institution
    Shankar Siva
    Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
    J Med Imaging Radiat Oncol 56:354-61. 2012
  8. doi request reprint Stereotactic radiotherapy for pulmonary oligometastases: a systematic review
    Shankar Siva
    Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia
    J Thorac Oncol 5:1091-9. 2010
  9. doi request reprint Impact of post-therapy positron emission tomography on prognostic stratification and surveillance after chemoradiotherapy for cervical cancer
    Shankar Siva
    Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia
    Cancer 117:3981-8. 2011
  10. doi request reprint Validation of a 4D-PET maximum intensity projection for delineation of an internal target volume
    Jason Callahan
    Centre for Molecular Imaging, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
    Int J Radiat Oncol Biol Phys 86:749-54. 2013

Collaborators

Detail Information

Publications27

  1. doi request reprint Abscopal effects of radiation therapy: a clinical review for the radiobiologist
    Shankar Siva
    Division of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, Vic, Australia Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Vic, Australia Electronic address
    Cancer Lett 356:82-90. 2015
    ..This review also outlines several suggested mechanisms for abscopal effects. ..
  2. pmc A prospective observational study of Gallium-68 ventilation and perfusion PET/CT during and after radiotherapy in patients with non-small cell lung cancer
    Shankar Siva
    Division of Radiation Oncology and Cancer Imaging, St Andrews Place, East Melbourne 3002, Australia
    BMC Cancer 14:740. 2014
    ..The ability to intensify treatment to achieve a better chance for cure is limited by the risk of injury to the surrounding lung...
  3. pmc An analysis of respiratory induced kidney motion on four-dimensional computed tomography and its implications for stereotactic kidney radiotherapy
    Shankar Siva
    Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia
    Radiat Oncol 8:248. 2013
    ..The purpose of this study is to assess patterns of kidney motion and investigate potential surrogates of kidney displacement with the view of ITV verification during treatment...
  4. doi request reprint 18F-FDG PET provides high-impact and powerful prognostic stratification in the staging of Merkel cell carcinoma: a 15-year institutional experience
    Shankar Siva
    Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia
    J Nucl Med 54:1223-9. 2013
    ..Merkel cell carcinoma (MCC) is a rare but aggressive skin cancer with limited evidence on the role of PET scanning. The primary aim of this study was to assess the impact of (18)F-FDG PET in the staging and management of MCC...
  5. doi request reprint A systematic review of stereotactic radiotherapy ablation for primary renal cell carcinoma
    Shankar Siva
    Division of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Centre, Vic, Australia
    BJU Int 110:E737-43. 2012
    ..The published evidence to date totals 126 patients worldwide. The majority of evidence is retrospective in nature. The present study adds context to the current literature by providing an overall summary of the evidence...
  6. doi request reprint Analysis of the impact of chest wall constraints on eligibility for a randomized trial of stereotactic body radiotherapy of peripheral stage I non-small cell lung cancer
    Shankar Siva
    Department of Radiation Oncology, University of Melbourne, Melbourne, Victoria, Australia
    J Med Imaging Radiat Oncol 56:654-60. 2012
    ..02 'CHISEL' study protocol excluded patients with tumours within 1 cm of the chest wall. The purpose of this study is to evaluate the implication of chest wall proximity constraints on patient eligibility, toxicity and potential accrual...
  7. doi request reprint Implementation of a lung radiosurgery program: technical considerations and quality assurance in an Australian institution
    Shankar Siva
    Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
    J Med Imaging Radiat Oncol 56:354-61. 2012
    ..The aim of this study was to critically assess the technical feasibility of performing stereotactic lung radiosurgery in an Australian institution...
  8. doi request reprint Stereotactic radiotherapy for pulmonary oligometastases: a systematic review
    Shankar Siva
    Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia
    J Thorac Oncol 5:1091-9. 2010
    ..The aim of this literature review is to critically assess the use of SBRT for the treatment of pulmonary metastases as judged by its effect on local control, survival, and toxicity...
  9. doi request reprint Impact of post-therapy positron emission tomography on prognostic stratification and surveillance after chemoradiotherapy for cervical cancer
    Shankar Siva
    Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia
    Cancer 117:3981-8. 2011
    ....
  10. doi request reprint Validation of a 4D-PET maximum intensity projection for delineation of an internal target volume
    Jason Callahan
    Centre for Molecular Imaging, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
    Int J Radiat Oncol Biol Phys 86:749-54. 2013
    ..In this report we validate the use of 4D-PET-MIP for the delineation of target volumes in both a phantom and in patients...
  11. doi request reprint Effect of different breathing patterns in the same patient on stereotactic ablative body radiotherapy dosimetry for primary renal cell carcinoma: a case study
    Daniel Pham
    Radiotherapy Services, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
    Med Dosim 38:304-8. 2013
    ..4D image guided radiation therapy verification strategies should focus on not only verifying ITV margin coverage but also the effect on the surrounding organs at risk. ..
  12. doi request reprint Vacuum immobilisation reduces tumour excursion and minimises intrafraction error in a cohort study of stereotactic ablative body radiotherapy for pulmonary metastases
    Shankar Siva
    Division of Cancer Imaging and Radiation Oncology, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia
    J Med Imaging Radiat Oncol 58:244-52. 2014
    ..The purpose of this study is to assess the impact of a vacuum immobilisation system on reproducibility of patient set-up, interfraction stability and tumour motion amplitude...
  13. doi request reprint High-resolution imaging of pulmonary ventilation and perfusion with 68Ga-VQ respiratory gated (4-D) PET/CT
    Jason Callahan
    Peter MacCallum Cancer Centre, Centre for Molecular Imaging, St Andrews Place, East Melbourne, Vic, Australia
    Eur J Nucl Med Mol Imaging 41:343-9. 2014
    ..We describe here the acquisition methodology for (68)Ga-VQ respiratory gated (4-D) PET/CT and the effects of respiratory motion on image coregistration in VQ scanning...
  14. doi request reprint Results of patient specific quality assurance for patients undergoing stereotactic ablative radiotherapy for lung lesions
    Nicholas Hardcastle
    Department of Physical Sciences, Peter MacCallum Cancer Centre, St Andrew s Place, East Melbourne, Vic, 3002, Australia
    Australas Phys Eng Sci Med 37:45-52. 2014
    ..QA is essential for complex radiotherapy deliveries such as SABR. We found individual patient QA helpful in setting up the technique and understanding potential weaknesses in SABR workflow, thus providing confidence in SABR delivery...
  15. doi request reprint Conventional margins not sufficient for post-prostatectomy prostate bed coverage: an analysis of 477 cone-beam computed tomography scans
    Suki Gill
    Department of Radiation Oncology, Peter MacCallum Cancer Centre, East Melbourne, Australia Electronic address
    Radiother Oncol 110:235-9. 2014
    ..To study prostate bed deformation, and compare coverage by 5 mm and 10mm posterior expansion PTV margins...
  16. doi request reprint Plan of the day selection for online image-guided adaptive post-prostatectomy radiotherapy
    Suki Gill
    Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia
    Radiother Oncol 107:165-70. 2013
    ....
  17. doi request reprint Multimodality guidance for accurate bronchoscopic insertion of fiducial markers
    Daniel P Steinfort
    Department of Medicine, University of Melbourne, Parkville, Australia Department of Respiratory Medicine, Royal Melbourne Hospital, Parkville, Australia Department Cancer Medicine, Peter MacCallum Cancer Institute, East Melbourne, Australia Division of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Institute, East Melbourne, Australia Department of Physical Sciences, Peter MacCallum Cancer Institute, East Melbourne, Australia Radiation Oncology, Genesis Cancer Care WA, Perth, Australia School of Surgery, University of Western Australia, Perth, Australia William Buckland Radiotherapy Centre, Prahran, Australia and Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia
    J Thorac Oncol 10:324-30. 2015
    ..Fiducial markers act as visible surrogates of tumor position during image-guided radiotherapy. Marker placement has been attempted percutaneously but is associated with high rates of pneumothorax and chest drain placement...
  18. doi request reprint A planning study investigating dual-gated volumetric arc stereotactic treatment of primary renal cell carcinoma
    Thomas Devereux
    Radiation Therapy Services, Peter MacCallum Cancer Centre, Melbourne, Australia Electronic address
    Med Dosim 40:82-8. 2015
    ..When summing the inhale and exhale plans together, dose to healthy tissue and OARs was optimized. However, gating VMAT plans would take longer to treat and is a factor that needs to be considered. ..
  19. doi request reprint Stereotactic ablative body radiation therapy for primary kidney cancer: a 3-dimensional conformal technique associated with low rates of early toxicity
    Daniel Pham
    Department of Radiotherapy Services, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia Department of Medical Imaging and Radiation Sciences, Monash University, Melbourne, Victoria, Australia Electronic address
    Int J Radiat Oncol Biol Phys 90:1061-8. 2014
    ..To describe our 3-dimensional conformal planning approaches and report early toxicities with stereotactic body radiation therapy for the management of primary renal cell carcinoma...
  20. pmc A pattern of early radiation-induced inflammatory cytokine expression is associated with lung toxicity in patients with non-small cell lung cancer
    Shankar Siva
    Division of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, Vic, Australia
    PLoS ONE 9:e109560. 2014
    ..We investigated the kinetics of RT induced plasma inflammatory cytokines in these patients in order to identify clinical predictors of toxicity...
  21. doi request reprint 68Ga-EDTA PET/CT Imaging and Plasma Clearance for Glomerular Filtration Rate Quantification: Comparison to Conventional 51Cr-EDTA
    Michael Hofman
    Centre for Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, Australia Department of Medicine, University of Melbourne, Melbourne, Australia
    J Nucl Med 56:405-9. 2015
    ..This study aimed to assess agreement between (68)Ga-EDTA GFR ((68)Ga-GFR) and (51)Cr-EDTA GFR ((51)Cr-GFR), using serial plasma sampling and PET imaging...
  22. doi request reprint Outcomes of stereotactic radiotherapy for cranial and extracranial metastatic renal cell carcinoma: a systematic review
    Gargi Kothari
    Division of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
    Acta Oncol 54:148-57. 2015
    ..The study objective was to analyse outcomes and toxicity of stereotactic radiotherapy in metastatic RCC...
  23. doi request reprint Advances in local and ablative treatment of oligometastasis in prostate cancer
    Henry Hi Yao
    Division of Urology, Department of Surgery, The University of Melbourne, Royal Melbourne Hospital, Parkville, Australia
    Asia Pac J Clin Oncol 10:308-21. 2014
    ..However, no direct comparison with ADT is available to suggest an improvement in overall survival. Further studies are required to determine the role of aggressive-targeted local therapy in oligometastatic CaP. ..
  24. doi request reprint Stereotactic body radiotherapy for primary prostate cancer: a systematic review
    Tze Jian Tan
    Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
    J Med Imaging Radiat Oncol 58:601-11. 2014
    ..There were no late grade 4 urinary toxicities seen. Late grade 2 rectal toxicity was reported in 0-11%, while 0.5% had a late grade 3 rectal toxicity. Late grade 4 rectal toxicity was reported in 0.2% of patients. ..
  25. doi request reprint Mobilization of viable tumor cells into the circulation during radiation therapy
    Olga A Martin
    Division of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Centre, East Melbourne, Vic, Australia Molecular Radiation Biology Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Vic, Australia The Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Vic, Australia
    Int J Radiat Oncol Biol Phys 88:395-403. 2014
    ..To determine whether radiation therapy (RT) could mobilize viable tumor cells into the circulation of non-small cell lung cancer (NSCLC) patients...
  26. doi request reprint Bronchoscopic delivery of lipiodol as a fiducial marker in lung tumors before radiotherapy
    Morgan Rose
    Department of Respiratory Medicine, Royal Melbourne Hospital, Parkville Department of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Centre, East Melbourne David Bickart Clinical Research Fellow, Department of Medicine, University Of Melbourne and Department of Cancer Medicine, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
    J Thorac Oncol 9:1579-83. 2014
    ..This article presents four cases which demonstrate the feasibility of bronchoscopic delivery of lipiodol as a fiducial marker, to aid in guided radiotherapy for certain lung tumors. ..
  27. pmc Ten-year results of quality assurance in radiotherapy chart round
    Bardia Taghavi Bayat
    Bendigo Base Hospital, Bendigo, Australia
    BMC Health Serv Res 13:148. 2013
    ..We present our experience collected over ten years from the use of the RANZCR audit instrument...