Research Topics
Species | A ObermairSummaryCountry: Australia Publications
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Publications
A phase III randomized clinical trial comparing laparoscopic or robotic radical hysterectomy with abdominal radical hysterectomy in patients with early stage cervical cancerAndreas Obermair
University of Queensland, School of Medicine, Department of Gynecological Oncology, Royal Brisbane and Women s Hospital, Herston, Brisbane, Queensland, Australia
J Minim Invasive Gynecol 15:584-8. 2008..In this study, TLRH or total robotic radical hysterectomy (TRRH) will be performed without a vaginally assisted portion of the procedure...
Pretreatment malnutrition and quality of life - association with prolonged length of hospital stay among patients with gynecological cancer: a cohort studyBrenda Laky
Queensland Centre for Gynaecological Cancer, Level 6 Ned Hanlon Building, The Royal Brisbane and Women s Hospital, Herston Queensland 4029, Australia
BMC Cancer 10:232. 2010..Identifying pretreatment factors associated with LOS in surgical patients may enable early intervention in order to reduce postoperative LOS...
Randomized trial of skin closure after laparotomy for gynaecological surgeryAndreas Obermair
Royal Brisbane and Women s Hospital, Queensland Centre for Gynaecological Cancer, Brisbane, Queensland, Australia
ANZ J Surg 77:460-3. 2007..New suture materials may provide patients with a better cosmetic outcome at similar pain and wound complication rate...
A new prognostic model for FIGO stage 1 epithelial ovarian cancerAndreas Obermair
Queensland Centre for Gynaecological Cancer, Medical School University of Queensland, Royal Brisbane Hospital, Brisbane, Australia
Gynecol Oncol 104:607-11. 2007..The purpose of this study was to evaluate the prognostic impact of preoperative CA-125 and to establish a prognostic index to identify patients in different risk categories...
Laparoscopy in the treatment of ovarian tumours of low malignant potentialAndreas Obermair
Queensland Centre for Gynaecological Cancer, Royal Brisbane and Women s Hospital, and Medical School, University of Queensland, Heston, Queensland, Australia
Aust N Z J Obstet Gynaecol 47:438-44. 2007..This review summarises the evidence to address these important questions...
Total laparoscopic hysterectomy versus total abdominal hysterectomy for obese women with endometrial cancerA Obermair
Royal Brisbane and Women s Hospital, School of Medicine, University of Queensland, QLD, Australia
Int J Gynecol Cancer 15:319-24. 2005..1%) in the TLH group. All other morbidity, as well as patterns of recurrence and survival were similar in both groups. These data justify a prospective randomized trial comparing TLH with TAH for the treatment of endometrial cancer...
Total laparoscopic hysterectomy for endometrial cancer: patterns of recurrence and survivalAndreas Obermair
King Edward Memorial Hospital for Women, Subiaco, WA, Australia
Gynecol Oncol 92:789-93. 2004..The objective of the current study was to evaluate the effect of the laparoscopic approach on patterns of recurrence, disease-free (DFS), and overall survival (OS) in patients with endometrial cancer...
Anemia before and during concurrent chemoradiotherapy in patients with cervical carcinoma: Effect on progression-free survivalA Obermair
Queensland Center for Gynaecological Cancer, Royal Women s Hospital, Queensland University of Technology, School of Public Health, Brisbane, Australia
Int J Gynecol Cancer 13:633-9. 2003..0% for nonanemic patients (P < 0.0002). In patients undergoing chemoradiation for cervical carcinoma, a low nadir Hb is highly predictive of shortened PFS, whereas the Hb before treatment is prognostically not significant...
Disease-free survival after vaginal vault brachytherapy versus observation for patients with node-negative intermediate-risk endometrial adenocarcinomaAndreas Obermair
Department of Obstetrics and Gynaecology, Central Clinical Division, The University of Queensland, Brisbane, Queensland, Australia
Gynecol Oncol 110:280-5. 2008..To compare the disease-free survival (DFS) of patients with surgical stage 1, intermediate-risk endometrial adenocarcinoma (EAC) treated with primary surgery with or without adjuvant vaginal vault brachytherapy (VVBT)...
Risk of endometrial cancer for women diagnosed with HNPCC-related colorectal carcinomaAndreas Obermair
School of Medicine, The University of Queensland and the Royal Brisbane and Women s Hospital, Herston, QLD, Australia
Int J Cancer 127:2678-84. 2010..001). Approximately one quarter of women diagnosed with Lynch syndrome-associated CRC developed EC within 10 years. This supports the sentinel cancer concept and suggests that active and early management is important for these women...
Endometrioid and clear cell ovarian cancers: a comparative analysis of risk factorsChristina M Nagle
Cancer and Population Studies Group, Queensland Institute of Medical Research, Brisbane, QLD, Australia
Eur J Cancer 44:2477-84. 2008..Endometrioid and clear cell ovarian cancers have some shared as well as some distinct risk factors, and therefore should be considered separately in studies of ovarian cancer...
Impact of hemoglobin levels before and during concurrent chemoradiotherapy on the response of treatment in patients with cervical carcinoma: preliminary resultsA Obermair
Queensland Center for Gynecological Cancer, Royal Women s Hospital, Brisbane, Queensland 4029, Australia
Cancer 92:903-8. 2001..For patients undergoing chemoradiation, there are no data available. The objective of this retrospective study was to examine the impact of anemia before and during chemoradiation in patients with cervical carcinoma...
Primary fallopian tube carcinoma: the Queensland experienceA Obermair
Queensland Center for Gynaecological Cancer, Ned Hanlon Building, Royal Women s Hospital, Herston, Queensland, Australia
Int J Gynecol Cancer 11:69-72. 2001..If primary surgical debulking cannot achieve macroscopic tumor clearence, the chance of survival is extremely low...
Skewed X chromosome inactivation and breast and ovarian cancer status: evidence for X-linked modifiers of BRCA1Felicity Lose
Cancer and Cell Biology Division, Queensland Institute of Medical Research, Herston, Brisbane, Queensland, Australia
J Natl Cancer Inst 100:1519-29. 2008....
Peritoneal cytology: impact on disease-free survival in clinical stage I endometrioid adenocarcinoma of the uterusA Obermair
Queensland Centre for Gynaecological Cancer, E Floor, Clinical Sciences Building, Royal Women s Hospital, Herston QLD 4029, Australia
Cancer Lett 164:105-10. 2001..001). The presence of positive peritoneal cytology in patients with clinically stage I endometrioid adenocarcinoma of the endometrium is considered an adverse prognostic factor...
Primary Bartholin gland carcinoma: a report of seven casesA Obermair
Queensland Centre for Gynaecological Cancer, Royal Women's Hospital, Herston, Australia
Aust N Z J Obstet Gynaecol 41:78-81. 2001..We present the first report of small cell neuroendocrine cancer of the Bartholin gland. Therapeutic principles in the management of vulval cancer at other sites appear to be appropriate for management of BGC...
Total laparoscopic versus open surgery for stage 1 endometrial cancer: the LACE randomized controlled trialM Janda
Queensland University of Technology, Centre for Health Research-Public Health, Kelvin Grove, Brisbane, Queensland, Australia
Contemp Clin Trials 27:353-63. 2006....
Polycystic ovary syndrome increases the risk of endometrial cancer in women aged less than 50 years: an Australian case-control studyEmily J Fearnley
School of Population Health, The University of Queensland, Herston Road, Herston, QLD 4006, Australia
Cancer Causes Control 21:2303-8. 2010..Our aim was to assess the associations between PCOS, PCOS symptoms, and risk of endometrial cancer in women aged less than 50 years...
Elderly patients with stage III or IV ovarian cancer: should they receive standard care?M Janda
School of Public Health, Queensland University of Technology, Brisbane, Queensland, Australia
Int J Gynecol Cancer 18:896-907. 2008..The risk factor profile established could be helpful to plan future clinical trials to establish optimal treatment for elderly patients with advanced stage ovarian cancer...
Patterns of recurrence and disease-free survival in advanced squamous cell carcinoma of the vulvaIsam Lataifeh
Queensland Centre for Gynaecological Cancer, Royal Brisbane and Women's Hospital, Butterfield Street, Herston, QLD 4029, Australia
Gynecol Oncol 95:701-5. 2004..The current FIGO staging system inaccurately reflects prognosis for patients with advanced vulval cancer. Clinical trials are warranted to investigate the benefit of systemic treatment...
Efficacy of oral or intrauterine device-delivered progestin in patients with complex endometrial hyperplasia with atypia or early endometrial adenocarcinoma: a meta-analysis and systematic review of the literatureJ Baker
Queensland University of Technology, Queensland, Australia
Gynecol Oncol 125:263-70. 2012..To investigate the efficacy of progestin treatment to achieve pathological complete response (pCR) in patients with complex atypical endometrial hyperplasia (CAH) or early endometrial adenocarcinoma (EC)...
Safety and efficacy of low anterior en bloc resection as part of cytoreductive surgery for patients with ovarian cancerA Obermair
Queensland Centre for Gynaecological Cancer, Royal Women s Hospital, Brisbane, Australia
Gynecol Oncol 83:115-20. 2001..To examine the feasibility and safety of a low anterior resection of the rectosigmoid plus adjacent pelvic tumour as part of primary cytoreduction for ovarian cancer...
Wrigley forceps to deliver a bulky uterus following a total laparoscopic hysterectomy for endometrial cancerCliff Neppe
Queensland Centre for Gynaecological Cancer, Royal Brisbane and Women s Hospital, Brisbane, Herston Queensland, Australia
Aust N Z J Obstet Gynaecol 45:444-5. 2005..We describe a new technique of removing a bulky uterus in a patient with endometrial cancer with the use of Wrigley forceps following a total laparoscopic hysterectomy...
Quality of life after total laparoscopic hysterectomy versus total abdominal hysterectomy for stage I endometrial cancer (LACE): a randomised trialMonika Janda
Queensland University of Technology, School of Public Health, Institute of Health and Biomedical Innovation, QLD, Australia
Lancet Oncol 11:772-80. 2010..The primary objective of stage 2 was to test the hypothesis that disease-free survival at 4.5 years is equivalent for TLH and TAH. Here, we present the results of stage 1...
Malnutrition among gynaecological cancer patientsB Laky
Queensland Centre for Gynaecological Cancer, The Royal Brisbane and Women s Hospital, Brisbane, Australia
Eur J Clin Nutr 61:642-6. 2007..To assess the nutritional status of patients with gynaecological cancer...
Body size and risk of epithelial ovarian and related cancers: a population-based case-control studyCatherine M Olsen
Cancer and Population Studies Group, Queensland Institute of Medical Research, Brisbane, Australia
Int J Cancer 123:450-6. 2008..These results add to the current evidence that obesity increases a woman's risk of developing distinct histological subtypes of ovarian cancer...
The significance of psammoma bodies on cervical cytology smearsJ L Nicklin
Division of Gynecologic Oncology, Royal Women s Hospital, Brisbane, Australia
Gynecol Oncol 83:6-9. 2001..The aim of this study was to determine the incidence of malignancy where psammoma bodies were detected on smear, to identify features that may be predictive of associated malignancy, and to make recommendations about management...
Feasibility and safety of total laparoscopic radical hysterectomyAndreas Obermair
King Edward Memorial Hospital for Women, Royal Women's Hospital, Herston, Australia
J Am Assoc Gynecol Laparosc 10:345-9. 2003..No case of port site metastasis occurred during follow-up. CONCLUSION: TLRH carries acceptably low morbidity that can be reduced with experience with the technique...
Molecular, pathologic, and clinical features of early-onset endometrial cancer: identifying presumptive Lynch syndrome patientsMichael D Walsh
Familial Cancer Laboratory and Molecular Cancer Epidemiology Laboratory, Queensland Institute of Medical Research, Herston, Australia
Clin Cancer Res 14:1692-700. 2008..The aim of this study was to determine the incidence of Lynch syndrome in a series of young-onset EC, and to identify molecular, clinical, and pathologic features that may alert clinicians to the presence of this disorder...
Prognostic importance of preoperative CA-125 in International Federation of Gynecology and Obstetrics stage I epithelial ovarian cancer: an Australian multicenter studySellva Paramasivam
Queensland Centre for Gynaecological Cancer, Medical School University of Quensland, Herston, Queensland, Australia
J Clin Oncol 23:5938-42. 2005..CONCLUSION: Complete surgical staging, histologic grade, and preoperative serum CA-125 levels are independent prognostic factors and should be included in the decision making for chemotherapy...
Postoperative analgesic requirements - total laparoscopic hysterectomy versus vaginal hysterectomyMarcelo Carraro Nascimento
Queensland Centre for Gynaecological Cancer, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia
Aust N Z J Obstet Gynaecol 45:140-3. 2005..Prospective randomised trials are warranted to compare analgesic requirements between patients submitted to TLH and VH...
Vulvar cancer patients' quality of life: a qualitative assessmentM Janda
Centre for Public Health Research, Queensland University of Technology, Kelvin Grove, QLD, Australia
Int J Gynecol Cancer 14:875-81. 2004..Results of this study revealed vulvar cancer-specific reductions in QOL for inclusion in the newly developed vulvar cancer-specific subscale...
Novel MUC1 splice variants are expressed in cervical carcinomaA Obermair
Queensland Centre for Gynaecological Cancer, Royal Brisbane Hospital, 6th Floor, Ned Hanlon Building, Teaching and Research, Herston, Brisbane, 4029, Australia
Gynecol Oncol 83:343-7. 2001..The MUC1 antigen can be used to identify epithelial cells from the background of hemopoietic cells. The present investigation describes patterns of overexpression of two novel MUC1 splice variants in human cervical carcinoma cell lines...
Total laparoscopic hysterectomy with a transvaginal tubeAnthony J McCartney
King Edward Memorial Hospital for Women and St. John of God Hospital, Subiaco, Australia
J Am Assoc Gynecol Laparosc 11:79-82. 2004..The McCartney tube is open at its vaginal (proximal) end and a cap covers the outer distal end. The total hysterectomy specimen, adnexa, and, if necessary, lymph nodes can be easily removed through the tube...
Efficacy of routine follow-up in patients with recurrent uterine cancerChristopher J Smith
Queensland Centre for Gynecological Cancer, Royal Brisbane and Women s Hospital, Herston, Queensland, Australia
Gynecol Oncol 107:124-9. 2007..To evaluate the efficacy of routine follow-up in patients with recurrent uterine cancer...
Total laparoscopic hysterectomy: the Brisbane learning curveAndrea J Garrett
Queensland Centre for Gynaecological Cancer, Royal Women s and Brisbane Hospital, Brisbane, Queensland, Australia
Aust N Z J Obstet Gynaecol 47:65-9. 2007..Total laparoscopic hysterectomy (TLH) is becoming more commonly used for gynaecological malignancies...
Pap smear screening history of women with squamous cell carcinoma and adenocarcinoma of the cervixSok Cheon Pak
Central Clinical Division, Department of Obstetrics and Gynaecology, The University of Queensland, and Queensland Centre for Gynaecological Cancer, The Royal Brisbane and Women s Hospital, Queensland, Australia
Aust N Z J Obstet Gynaecol 47:504-7. 2007..Since the introduction of the Pap smear screening, the incidence of squamous cell carcinoma (SCC) has decreased significantly, but the incidence of adenocarcinoma (AC) relative to SCC has increased...
Expression of MUC1 splice variants in benign and malignant ovarian tumoursAndreas Obermair
Queensland Centre for Gynaecological Cancer, Royal Brisbane Hospital, Brisbane, Australia
Int J Cancer 100:166-71. 2002..Expression of MUC1 splice variants A, D, X, Y, Z and REP is associated with the presence of malignancy, whereas expression of MUC1/SEC is associated with the absence of malignancy...
Advanced cytoreductive surgery: Asia Pacific perspectiveAlexander J Crandon
Queensland Centre for Gynaecological Cancer, Brisbane, Australia
Gynecol Oncol 114:S15-21. 2009..While advanced cytoreductive surgery is feasible, it is only in this team environment, limited to major multidisciplinary hospitals, that it can be safely achieved by meticulous attention to detail at all levels...
Potential hospital cost-savings attributed to improvements in outcomes for colorectal cancer surgery following self-auditLouisa G Gordon
Queensland Institute of Medical Research, Genetics and Population Health Division, PO Royal Brisbane Hospital, Herston Q4029, Brisbane, Australia
BMC Surg 10:4. 2010..The aim of this study was to estimate the potential cost-savings for Australian hospitals from improved surgical performance for colorectal surgery attributed to a surgical self-audit program...
Vulval Keratoacanthoma: a case reportMarcelo Carraro Nascimento
Queensland Centre for Gynaecological Cancer, Royal Brisbane and Women's Hospital, 6th Floor, Ned Hanlon Building, Butterfield Street, Herston, QLD 4029, Australia
Gynecol Oncol 97:674-6. 2005..Consideration to the occurrence of vulval KA is important to avoid both an erroneous diagnosis of vulval SCC and the associated consequences of radical surgery...
Vascular endothelial growth factor splice variants and their prognostic value in breast and ovarian cancerMargit Stimpfl
Division of Gynecology, Molecular Oncology Group, Department of Obstetrics and Gynecology, University of Vienna, A-1090 Vienna, Austria
Clin Cancer Res 8:2253-9. 2002..CONCLUSIONS: Even though expression levels of VEGF have been shown to be important for tumor invasion and progression, the present data indicate no relation of VEGF isoform pattern with invasion and progression...
Thrombocytosis and anaemia in women with recurrent ovarian cancer prior to a second-line chemotherapyAndreas Nather
Department of Gynecology and Obstetrics, Vienna University Medical School, A 1090 Vienna, Wahringer Gurtel 18 20, Austria
Anticancer Res 23:2991-4. 2003..To investigate the incidence and the prognostic value of platelet count and serum haemoglobin (Hb) in patients with recurrent ovarian cancer prior to second-line chemotherapy...
Prognostic value of laminin-5 in serous adenocarcinomas of the ovaryPetra Kohlberger
Department of Gynecology and Obstetrics, Vienna University Medical School, Waehringer Guertel 18 20, A 1090 Vienna, Austria
Anticancer Res 22:3541-4. 2002..The aim of the present study was to evaluate the prognostic significance of the expression of Laminin in patients suffering from malignant serous surface epithelial-stromal tumors of the ovary...
The impact of positive peritoneal washings and serosal and adnexal involvement on survival in patients with stage IIIA uterine cancerOliver Preyer
Department of Obstetrics and Gynecology, Division of Gynecology, University of Vienna Medical School, Waehringer Guertel 18 20, A 1090 Vienna, Austria
Gynecol Oncol 86:269-73. 2002..We also sought to determine patterns of recurrence in patients with this disease...
Impact of multiple HPV infection on response to treatment and survival in patients receiving radical radiotherapy for cervical cancerBarbara Bachtiary
Department of Radiotherapy and Radiobiology, University Hospital Vienna, Wahringer Gurtel 18 20, A 1090 Vienna, Austria
Int J Cancer 102:237-43. 2002..Our results demonstrate that the presence of multiple HPV types is associated with poor response and with reduced survival in cervical cancer patients who receive radiotherapy as the primary treatment...
Preoperative serum CA125 in surgical stage 1 epithelial ovarian cancerAndreas Obermair
Gynecol Oncol 107:357-8. 2007
Incidence of anaemia in breast cancer patients receiving adjuvant chemotherapyUrsula Denison
Department of Obstetrics and Gynecology, General Hospital Lainz, Vienna, Austria
Breast Cancer Res Treat 79:347-53. 2003..Only 18.6% of the patients who were found to be anaemic received anaemia treatment. The two most important factors for developing anaemia are the kind of surgery and the Hb level prior to chemotherapy...
Serum VEGF levels in patients undergoing primary radiotherapy for cervical cancer: impact on progression-free survivalBarbara Bachtiary
Department of Radiotherapy and Radiobiology, University Hospital Vienna, Wahringer Gurtel 18 20, Vienna, Austria
Cancer Lett 179:197-203. 2002..Elevated pre-therapeutic serum VEGF levels are associated with poor response and a shorter time to progression in patients with cervical cancer undergoing primary radiotherapy...
Lynch syndrome in women less than 50 years of age with endometrial cancerMichael D Walsh
Obstet Gynecol 112:943. 2008
Lymphedema after gynecological cancer treatment : prevalence, correlates, and supportive care needsVanessa Beesley
Queensland University of Technology, School of Public Health, Institute of Health and Biomedical Innovation, Brisbane, Australia
Cancer 109:2607-14. 2007..Few studies have evaluated lymphedema after gynecological cancer treatment. The aim of this research was to establish prevalence, correlates, and supportive care needs of gynecological cancer survivors who develop lymphedema...
Ki-67 and vascular endothelial growth factor expression in uterine leiomyosarcomaKlaus Mayerhofer
Department of Gynecology and Obstetrics, University of Vienna Medical School, Vienna, Austria
Gynecol Oncol 92:175-9. 2004..The importance of different prognostic parameters in these malignancies remains controversial. The aim of the present study was to evaluate the prognostic value of Ki-67 and vascular endothelial growth factor (VEGF) in uterine LMS...
Re: Excess of early onset multiple myeloma in endometrial cancer probands and their relatives suggests common susceptibilityAmanda Spurdle
Gynecol Oncol 109:153; author reply 154. 2008
Comparison of different nutritional assessments and body-composition measurements in detecting malnutrition among gynecologic cancer patientsBrenda Laky
Queensland Centre for Gynaecological Cancer, The Royal Brisbane and Women s Hospital, Brisbane, Australia
Am J Clin Nutr 87:1678-85. 2008..Few studies have assessed global nutritional assessment tools and body-composition measurements in gynecologic cancer patients...
