Sebastian J van Hal

Summary

Affiliation: New South Wales
Country: Australia

Publications

  1. ncbi request reprint Support for the EUCAST and revised CLSI fluconazole clinical breakpoints by Sensititre® YeastOne® for Candida albicans: a prospective observational cohort study
    S J van Hal
    Department of Microbiology and Infectious Diseases, Royal Prince Alfred Hospital, Camperdown, Sydney, Australia
    J Antimicrob Chemother 69:2210-4. 2014
  2. pmc Whole genome sequence analysis of the first Australian OXA-48-producing outbreak-associated Klebsiella pneumoniae isolates: the resistome and in vivo evolution
    Bjorn A Espedido
    Antibiotic Resistance and Mobile Elements Group, School of Medicine, University of Western Sydney, New South Wales, Australia
    PLoS ONE 8:e59920. 2013
  3. pmc Is it time to replace vancomycin in the treatment of methicillin-resistant Staphylococcus aureus infections?
    Sebastiaan J van Hal
    Department of Microbiology and Infectious Diseases, Royal Prince Alfred Hospital, Camperdown, Sydney, Australia
    Clin Infect Dis 56:1779-88. 2013
  4. pmc Systematic review and meta-analysis of vancomycin-induced nephrotoxicity associated with dosing schedules that maintain troughs between 15 and 20 milligrams per liter
    S J van Hal
    Department of Microbiology and Infectious Diseases, Royal Prince Alfred Hospital, Sydney, Australia
    Antimicrob Agents Chemother 57:734-44. 2013
  5. pmc Predictors of mortality in Staphylococcus aureus Bacteremia
    Sebastian J van Hal
    Department of Microbiology and Infectious Diseases, Sydney South West Pathology Service Liverpool, South Western Sydney Local Health Network, Sydney, New South Wales, Australia
    Clin Microbiol Rev 25:362-86. 2012
  6. doi request reprint New Gram-positive antibiotics: better than vancomycin?
    Sebastiaan J van Hal
    Department of Microbiology and Infectious Diseases, Sydney South West Pathology Service Liverpool, South Western Sydney Local Health Network, NSW, Sydney, Australia
    Curr Opin Infect Dis 24:515-20. 2011
  7. doi request reprint Methicillin-resistant Staphylococcus aureus vancomycin susceptibility testing: methodology correlations, temporal trends and clonal patterns
    Sebastiaan J van Hal
    Department of Microbiology and Infectious Diseases, Sydney South West Pathology Service Liverpool, South Western Sydney Local Health Network, NSW, Sydney, Australia
    J Antimicrob Chemother 66:2284-7. 2011
  8. pmc Vancomycin heteroresistance is associated with reduced mortality in ST239 methicillin-resistant Staphylococcus aureus blood stream infections
    Sebastiaan J van Hal
    Department of Microbiology and Infectious Diseases, Sydney South West Pathology Service Liverpool Hospital, Sydney, New South Wales, Australia
    PLoS ONE 6:e21217. 2011
  9. pmc Performance of various testing methodologies for detection of heteroresistant vancomycin-intermediate Staphylococcus aureus in bloodstream isolates
    Sebastian J van Hal
    Department of Microbiology and Infectious Diseases, Liverpool Hospital, Locked Bag 7090, Liverpool BC, NSW 1871, Australia
    J Clin Microbiol 49:1489-94. 2011
  10. pmc Systematic review and meta-analysis of the significance of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates
    Sebastiaan J van Hal
    Department of Microbiology and Infectious Diseases, Liverpool Hospital, Liverpool BC, NSW, Sydney, Australia
    Antimicrob Agents Chemother 55:405-10. 2011

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Support for the EUCAST and revised CLSI fluconazole clinical breakpoints by Sensititre® YeastOne® for Candida albicans: a prospective observational cohort study
    S J van Hal
    Department of Microbiology and Infectious Diseases, Royal Prince Alfred Hospital, Camperdown, Sydney, Australia
    J Antimicrob Chemother 69:2210-4. 2014
    ..were established following consideration of clinical outcomes in patients with oesophageal candidiasis. We sought to further determine the validity of the current CBPs based on data from a prospective candidaemia study...
  2. pmc Whole genome sequence analysis of the first Australian OXA-48-producing outbreak-associated Klebsiella pneumoniae isolates: the resistome and in vivo evolution
    Bjorn A Espedido
    Antibiotic Resistance and Mobile Elements Group, School of Medicine, University of Western Sydney, New South Wales, Australia
    PLoS ONE 8:e59920. 2013
    ..Collectively, these SNPs are likely to be associated with changes in virulence (at least to some extent) that have refined the in vivo colonization capacity of the original outbreak isolate...
  3. pmc Is it time to replace vancomycin in the treatment of methicillin-resistant Staphylococcus aureus infections?
    Sebastiaan J van Hal
    Department of Microbiology and Infectious Diseases, Royal Prince Alfred Hospital, Camperdown, Sydney, Australia
    Clin Infect Dis 56:1779-88. 2013
    ..In the absence of further data, the Infectious Diseases Society of America guidelines remain relevant and inform clinicians of best practice for treating patients with MRSA infections...
  4. pmc Systematic review and meta-analysis of vancomycin-induced nephrotoxicity associated with dosing schedules that maintain troughs between 15 and 20 milligrams per liter
    S J van Hal
    Department of Microbiology and Infectious Diseases, Royal Prince Alfred Hospital, Sydney, Australia
    Antimicrob Agents Chemother 57:734-44. 2013
    ..The collective literature indicates that an exposure-nephrotoxicity relationship for vancomycin exists. The probability of a nephrotoxic event increased as a function of the trough concentration and duration of therapy...
  5. pmc Predictors of mortality in Staphylococcus aureus Bacteremia
    Sebastian J van Hal
    Department of Microbiology and Infectious Diseases, Sydney South West Pathology Service Liverpool, South Western Sydney Local Health Network, Sydney, New South Wales, Australia
    Clin Microbiol Rev 25:362-86. 2012
    ..Future international collaborative studies are required to tease out the relative contributions of various factors to mortality, which would enable the optimization of SAB management and patient outcomes...
  6. doi request reprint New Gram-positive antibiotics: better than vancomycin?
    Sebastiaan J van Hal
    Department of Microbiology and Infectious Diseases, Sydney South West Pathology Service Liverpool, South Western Sydney Local Health Network, NSW, Sydney, Australia
    Curr Opin Infect Dis 24:515-20. 2011
    ..Despite concerns about vancomycin use in the treatment of multidrug-resistant Gram positives, evidence for better therapeutic outcomes with alternative antibiotics is lacking. This review focuses on recent advances...
  7. doi request reprint Methicillin-resistant Staphylococcus aureus vancomycin susceptibility testing: methodology correlations, temporal trends and clonal patterns
    Sebastiaan J van Hal
    Department of Microbiology and Infectious Diseases, Sydney South West Pathology Service Liverpool, South Western Sydney Local Health Network, NSW, Sydney, Australia
    J Antimicrob Chemother 66:2284-7. 2011
    ..To determine the correlation between various vancomycin MIC testing methodologies and explore the phenomenon of MIC creep...
  8. pmc Vancomycin heteroresistance is associated with reduced mortality in ST239 methicillin-resistant Staphylococcus aureus blood stream infections
    Sebastiaan J van Hal
    Department of Microbiology and Infectious Diseases, Sydney South West Pathology Service Liverpool Hospital, Sydney, New South Wales, Australia
    PLoS ONE 6:e21217. 2011
    ....
  9. pmc Performance of various testing methodologies for detection of heteroresistant vancomycin-intermediate Staphylococcus aureus in bloodstream isolates
    Sebastian J van Hal
    Department of Microbiology and Infectious Diseases, Liverpool Hospital, Locked Bag 7090, Liverpool BC, NSW 1871, Australia
    J Clin Microbiol 49:1489-94. 2011
    ..Implementation of any testing strategy would therefore be dependent on balancing cost with accuracy in a given population and clinical context...
  10. pmc Systematic review and meta-analysis of the significance of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates
    Sebastiaan J van Hal
    Department of Microbiology and Infectious Diseases, Liverpool Hospital, Liverpool BC, NSW, Sydney, Australia
    Antimicrob Agents Chemother 55:405-10. 2011
    ..Despite this, 30-day mortality rates were similar to those for VSSA infections (odds ratio [OR], 1.18; 95% CI, 0.81 to 1.74). The optimal therapy for hVISA requires further study...
  11. pmc Impact of ethnicity and socio-economic status on Staphylococcus aureus bacteremia incidence and mortality: a heavy burden in Indigenous Australians
    Steven Y C Tong
    Tropical and Emerging Infectious Diseases Division, Menzies School of Health Research, Darwin, Northern Territory, Australia
    BMC Infect Dis 12:249. 2012
    ..Investigations of the impact of ethnicity and socio-economic status on incidence and outcomes of Staphylococcus aureus bacteraemia are limited...