Richard A Scolyer

Summary

Affiliation: New South Wales
Country: Australia

Publications

  1. ncbi request reprint Tumor mitotic rate is a more powerful prognostic indicator than ulceration in patients with primary cutaneous melanoma: an analysis of 3661 patients from a single center
    Manuela F Azzola
    Sydney Melanoma Unit, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Cancer 97:1488-98. 2003
  2. ncbi request reprint Merkel cell carcinoma: assessing the effect of wide local excision, lymph node dissection, and radiotherapy on recurrence and survival in early-stage disease--results from a review of 82 consecutive cases diagnosed between 1992 and 2004
    James Jabbour
    Sydney Cancer Centre, Sydney, Australia
    Ann Surg Oncol 14:1943-52. 2007
  3. doi request reprint False-negative sentinel node biopsy because of obstruction of lymphatics by metastatic melanoma: the value of ultrasound in conjunction with preoperative lymphoscintigraphy
    Tai K Lam
    Melanoma Institute Australia, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Melanoma Res 19:94-9. 2009
  4. ncbi request reprint Combined naevus: a benign lesion frequently misdiagnosed both clinically and pathologically as melanoma
    Richard A Scolyer
    Department of Anatomical Pathology, Royal Prince Alfred Hospital, Camperdown, Australia
    Pathology 36:419-27. 2004
  5. pmc The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a
    Therese M Becker
    Westmead Institute for Cancer Research, University of Sydney, Westmead Millennium Institute and Westmead Hospital, Australia
    Mol Cancer 8:4. 2009
  6. ncbi request reprint Parachordoma is not distinguishable from axial chordoma using immunohistochemistry
    Richard A Scolyer
    Department of Anatomical Pathology, Royal Prince Alfred Hospital, Sydney, Australia
    Pathol Int 54:364-70. 2004
  7. ncbi request reprint Failure to remove true sentinel nodes can cause failure of the sentinel node biopsy technique: evidence from antimony concentrations in false-negative sentinel nodes from melanoma patients
    Richard A Scolyer
    Sydney Melanoma Unit and Melanoma and Skin Cancer Research Institute, Royal Prince Alfred Hospital, Camperdown, Australia
    Ann Surg Oncol 11:174S-8S. 2004
  8. ncbi request reprint Interobserver reproducibility of histopathologic prognostic variables in primary cutaneous melanomas
    Richard A Scolyer
    Department of Anatomical Pathology, and Sydney Melanoma Unit, and the Melanoma and Skin Cancer Research Institute, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Am J Surg Pathol 27:1571-6. 2003
  9. ncbi request reprint Pathology of melanocytic lesions: new, controversial, and clinically important issues
    Richard A Scolyer
    Sydney Melanoma Unit and Melanoma and Skin Cancer Research Institute, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    J Surg Oncol 86:200-11. 2004
  10. ncbi request reprint Immunohistochemical stains fail to increase the detection rate of micrometastatic melanoma in completion regional lymph node dissection specimens
    Richard A Scolyer
    Melanoma and Skin Cancer Research Institute, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Melanoma Res 14:263-8. 2004

Collaborators

Detail Information

Publications116 found, 100 shown here

  1. ncbi request reprint Tumor mitotic rate is a more powerful prognostic indicator than ulceration in patients with primary cutaneous melanoma: an analysis of 3661 patients from a single center
    Manuela F Azzola
    Sydney Melanoma Unit, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Cancer 97:1488-98. 2003
    ..The current study was performed to determine whether tumor mitotic rate (TMR) is a useful, independent prognostic factor in patients with localized cutaneous melanoma...
  2. ncbi request reprint Merkel cell carcinoma: assessing the effect of wide local excision, lymph node dissection, and radiotherapy on recurrence and survival in early-stage disease--results from a review of 82 consecutive cases diagnosed between 1992 and 2004
    James Jabbour
    Sydney Cancer Centre, Sydney, Australia
    Ann Surg Oncol 14:1943-52. 2007
    ..Wide surgical excision, lymph node dissection, and radiotherapy have been used with varying efficacy in the management of early-stage Merkel cell carcinoma...
  3. doi request reprint False-negative sentinel node biopsy because of obstruction of lymphatics by metastatic melanoma: the value of ultrasound in conjunction with preoperative lymphoscintigraphy
    Tai K Lam
    Melanoma Institute Australia, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Melanoma Res 19:94-9. 2009
    ..They also highlight the advantages of using ultrasound to assess lymph nodes in any node fields to which lymphatic drainage occurs from a primary tumour site...
  4. ncbi request reprint Combined naevus: a benign lesion frequently misdiagnosed both clinically and pathologically as melanoma
    Richard A Scolyer
    Department of Anatomical Pathology, Royal Prince Alfred Hospital, Camperdown, Australia
    Pathology 36:419-27. 2004
    ..They are prone to clinical and pathological misdiagnosis as melanoma. Misdiagnosis may result in inappropriate treatment, patient anxiety and medicolegal consequences...
  5. pmc The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a
    Therese M Becker
    Westmead Institute for Cancer Research, University of Sydney, Westmead Millennium Institute and Westmead Hospital, Australia
    Mol Cancer 8:4. 2009
    ..To identify such functions we conducted a yeast-two-hybrid screen for novel p16INK4a binding partners...
  6. ncbi request reprint Parachordoma is not distinguishable from axial chordoma using immunohistochemistry
    Richard A Scolyer
    Department of Anatomical Pathology, Royal Prince Alfred Hospital, Sydney, Australia
    Pathol Int 54:364-70. 2004
    ..The results also suggest that parachordoma might not be easily distinguished immunohistochemically from axial chordoma (and therefore also from so-called chordoma periphericum)...
  7. ncbi request reprint Failure to remove true sentinel nodes can cause failure of the sentinel node biopsy technique: evidence from antimony concentrations in false-negative sentinel nodes from melanoma patients
    Richard A Scolyer
    Sydney Melanoma Unit and Melanoma and Skin Cancer Research Institute, Royal Prince Alfred Hospital, Camperdown, Australia
    Ann Surg Oncol 11:174S-8S. 2004
    ..Our results suggest that an FN SNB can occur because of failure to remove the true SN as well as histopathologic misdiagnosis...
  8. ncbi request reprint Interobserver reproducibility of histopathologic prognostic variables in primary cutaneous melanomas
    Richard A Scolyer
    Department of Anatomical Pathology, and Sydney Melanoma Unit, and the Melanoma and Skin Cancer Research Institute, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Am J Surg Pathol 27:1571-6. 2003
    ..However, few studies have assessed the accuracy and reproducibility with which these features of a melanoma are recorded by histopathologists...
  9. ncbi request reprint Pathology of melanocytic lesions: new, controversial, and clinically important issues
    Richard A Scolyer
    Sydney Melanoma Unit and Melanoma and Skin Cancer Research Institute, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    J Surg Oncol 86:200-11. 2004
    ....
  10. ncbi request reprint Immunohistochemical stains fail to increase the detection rate of micrometastatic melanoma in completion regional lymph node dissection specimens
    Richard A Scolyer
    Melanoma and Skin Cancer Research Institute, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Melanoma Res 14:263-8. 2004
    ..We therefore recommend only H&E staining on sections of all lymph nodes in CLND specimens from melanoma patients...
  11. ncbi request reprint Antimony concentrations in nodal tissue can confirm sentinel node identity
    Richard A Scolyer
    Sydney Melanoma Unit, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Mod Pathol 17:1191-7. 2004
    ....
  12. ncbi request reprint Pathologic examination of sentinel lymph nodes from melanoma patients
    Richard A Scolyer
    Department of Anatomical Pathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Semin Diagn Pathol 25:100-11. 2008
    ..At present, the role of nonhistopathologic methods of SN evaluation, such as reverse transcription polymerase chain reaction (RT-PCR) and magnetic resonance spectroscopy, remains unclear, and these techniques require further evaluation...
  13. ncbi request reprint The detection and significance of melanoma micrometastases in sentinel nodes
    Richard A Scolyer
    Sydney Melanoma Unit, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia
    Surg Oncol 17:165-74. 2008
    ....
  14. doi request reprint False negative sentinel lymph node biopsies in melanoma may result from deficiencies in nuclear medicine, surgery, or pathology
    Rooshdiya Z Karim
    Department of Anatomical Pathology, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Ann Surg 247:1003-10. 2008
    ..To investigate a cohort of melanoma patients with false negative (FN) sentinel node (SN) biopsies (SNBs) to identify the reasons for the FN result...
  15. doi request reprint Effects of BRAF inhibitors on human melanoma tissue before treatment, early during treatment, and on progression
    Georgina V Long
    Melanoma Institute Australia, Sydney, NSW, Australia
    Pigment Cell Melanoma Res 26:499-508. 2013
    ..The addition of therapies targeting the cell cycle machinery may improve the response and duration of BRAFi, and investigation of the mechanisms of apoptosis may provide additional therapeutic targets. ..
  16. doi request reprint Lactate dehydrogenase 5 expression in melanoma increases with disease progression and is associated with expression of Bcl-XL and Mcl-1, but not Bcl-2 proteins
    Liqing Zhuang
    Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Mod Pathol 23:45-53. 2010
    ..The strong correlation of LDH-5 expression with Mcl-1 expression suggests that treatment strategies inhibiting the activity of Mcl-1 in melanoma patients should be investigated...
  17. ncbi request reprint Progression in melanoma is associated with decreased expression of death receptors for tumor necrosis factor-related apoptosis-inducing ligand
    Liqing Zhuang
    Discipline of Pathology, Faculty of Medicine, University of Sydney, Sydney, New South Wales 2006, Australia
    Hum Pathol 37:1286-94. 2006
    ..This suggests that melanoma may not respond to treatment with TRAIL unless given with agents that increase the expression of TRAIL death receptors...
  18. doi request reprint Clinical and pathologic factors associated with distant metastasis and survival in patients with thin primary cutaneous melanoma
    Rajmohan Murali
    Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Ann Surg Oncol 19:1782-9. 2012
    ..We sought to identify clinical and pathologic factors associated with distant metastasis and survival in a large number of patients with thin melanoma treated at a single institution...
  19. pmc Diagnostic accuracy of fine needle biopsy for metastatic melanoma and its implications for patient management
    Anna Doubrovsky
    Sydney Melanoma Unit, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, NSW, 2050, Australia
    Ann Surg Oncol 15:323-32. 2008
    ..In this study, the accuracy of FNB for the diagnosis of metastatic melanoma was investigated...
  20. ncbi request reprint The site of infection and ethnicity of the patient influence the biological pathways to HPV-induced mucosal cancer
    Wei Li
    Sydney Head and Neck Cancer Institute, Royal Prince Alfred Hospital, Sydney, Australia
    Mod Pathol 17:1031-7. 2004
    ..These findings represent new evidence that the molecular pathways to human papillomavirus-induced mucosal cancer may be influenced by anatomic location and ethnicity...
  21. ncbi request reprint Outcome in 846 cutaneous melanoma patients from a single center after a negative sentinel node biopsy
    Vivian S K Yee
    Sydney Melanoma Unit, Sydney Cancer Centre, Gloucester House, Royal Prince Alfred Hospital, Missenden Road, Camperdown, 2050 New South Wales, Australia
    Ann Surg Oncol 12:429-39. 2005
    ..A negative sentinel node biopsy (SNB) implies a good prognosis for melanoma patients. The purpose of this study was to determine the long-term outcome for melanoma patients with a negative SNB...
  22. pmc Confirmation of sentinel lymph node identity by analysis of fine-needle biopsy samples using inductively coupled plasma-mass spectrometry
    Alison Beavis
    Department of Chemistry, Materials and Forensic Science, University of Technology, Sydney, New South Wales, Australia
    Ann Surg Oncol 15:934-40. 2008
    ..This involved the use of inductively coupled plasma-mass spectrometry (ICP-MS) to analyze antimony concentrations in fine-needle biopsy (FNB) samples from surgically procured lymph nodes...
  23. doi request reprint The importance of adequate primary tumor excision margins and sentinel node biopsy in achieving optimal locoregional control for patients with thick primary melanomas
    Sandro Pasquali
    Melanoma Institute Australia, Sydney, NSW, Australia
    Ann Surg 258:152-7. 2013
    ..This study sought to investigate the impact of histopathologically measured excision margins and SNB on local and locoregional disease control in patients with primary cutaneous melanomas more than 4 mm thick...
  24. doi request reprint Sentinel lymph nodes containing very small (<0.1 mm) deposits of metastatic melanoma cannot be safely regarded as tumor-negative
    Rajmohan Murali
    Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, and Discipline of Pathology, Sydney Medical School, The University of Sydney, Sydney, NSW, Australia
    Ann Surg Oncol 19:1089-99. 2012
    ....
  25. doi request reprint Targeted high-resolution ultrasound is not an effective substitute for sentinel lymph node biopsy in patients with primary cutaneous melanoma
    Amira Sanki
    Melanoma Institute Australia and Sydney Melanoma Unit, Royal Prince Alfred and Mater Hospitals, Sydney, New South Wales, Australia
    J Clin Oncol 27:5614-9. 2009
    ....
  26. ncbi request reprint The expression of key cell cycle markers and presence of human papillomavirus in squamous cell carcinoma of the tonsil
    Wei Li
    Sydney Head and Neck Cancer Institute, PO Box M 142, Missenden Road, Camperdown, NSW 2050, Australia
    Head Neck 26:1-9. 2004
    ..Human papillomavirus (HPV) might have an etiologic role in these cancers at particular sites. Few studies have compared cell cycle protein expression in HPV-positive and HPV-negative tumors in this region...
  27. ncbi request reprint Subungual melanoma: a study of 124 cases highlighting features of early lesions, potential pitfalls in diagnosis, and guidelines for histologic reporting
    Kong Bing Tan
    Department of Anatomical Pathology, Royal Prince Alfred Hospital, Camperdown, Australia
    Am J Surg Pathol 31:1902-12. 2007
    ..Guidelines for the reporting of SUMs are also presented. Knowledge and recognition of the pathologic features of SUMs and the important features that distinguish them from nevi should reduce the frequency of misdiagnosis...
  28. ncbi request reprint Sentinel lymph node biopsy in pediatric and adolescent cutaneous melanoma patients
    Robert Howman-Giles
    Sydney Melanoma Unit and Melanoma Institute Australia, Royal Prince Alfred and Mater Hospitals, Sydney, NSW, Australia
    Ann Surg Oncol 17:138-43. 2010
    ..The present study takes advantage of the large Sydney Melanoma Unit (SMU) database to clarify this issue...
  29. ncbi request reprint Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma
    Liqing Zhuang
    Discipline of Pathology, Faculty of Medicine, The University of Sydney, Sydney, NSW, Australia
    Mod Pathol 20:416-26. 2007
    ..These findings have important implications for the development of treatments targeting antiapoptotic proteins in patients with melanoma...
  30. ncbi request reprint Histomorphologic assessment and interobserver diagnostic reproducibility of atypical spitzoid melanocytic neoplasms with long-term follow-up
    Pedram Gerami
    Department of Dermatology Robert H Lurie Cancer Center Department of Preventive Medicine and the Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Il Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY Department of Pathology and Laboratory Medicine, Dermatopathology, UCLA Medical Center, Los Angeles Departments of Pathology and Dermatology, University of California, San Francisco, San Francisco, CA Pathology Service, Massachusetts General Hospital, Boston, MA Department of Pathology, University of Pennsylvania, Philadelphia Rabkin Dermatopathology Laboratory, P C, Tarentum, PA Departments of Pathology Dermatology, University of Michigan Medical Center, Ann Arbor, MI Department of Pathology, Section of Dermatopathology Department of Dermatology, The University of Texas MD Anderson Cancer Center, Houston, TX Department of Histopathology, Royal Surrey County Hospital and Division of Clinical Medicine, University of Surrey, Guildford, Surrey, UK Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Melanoma Institute Australia and The University of Sydney, NSW, Australia Departments of Dermatology, Chonnam National University Medical School, Gwangju, Korea
    Am J Surg Pathol 38:934-40. 2014
    ..This study may provide some guidance regarding histologic assessment of these enigmatic tumors...
  31. ncbi request reprint Argyrophilic staining of nucleolar organizer region count and morphometry in benign and malignant melanocytic lesions
    Ling Xi L Li
    Melanoma and Skin Cancer Research Institute, Sydney Melanoma Unit, Royal Prince Alfred Hospital, Camperdown, New South Wales 2050, Australia
    Am J Dermatopathol 25:190-7. 2003
    ..The results suggest that both AgNOR count and morphology help to separate benign and malignant melanocytic lesions and that the combination of both sets of parameters improves their discriminating ability...
  32. ncbi request reprint A sentinel node biopsy does not increase the incidence of in-transit metastasis in patients with primary cutaneous melanoma
    Daan van Poll
    Sydney Melanoma Unit, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, New South Wales 2050, Australia
    Ann Surg Oncol 12:597-608. 2005
    ..It has been suggested that performing a sentinel node biopsy (SNB) in patients with cutaneous melanoma increases the incidence of in-transit metastasis (ITM)...
  33. pmc Oncogenic B-RAF(V600E) signaling induces the T-Box3 transcriptional repressor to repress E-cadherin and enhance melanoma cell invasion
    Suzanah C Boyd
    University of Sydney at Westmead Millennium Institute, Westmead Hospital, Westmead, New South Wales, Australia
    J Invest Dermatol 133:1269-77. 2013
    ..We propose that this B-RAF/Tbx3/E-cadherin pathway has a critical role in promoting the metastasis of B-RAF-mutant melanomas...
  34. doi request reprint Sentinel lymph node biopsy in patients with thin primary cutaneous melanoma
    Rajmohan Murali
    Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
    Ann Surg 255:128-33. 2012
    ....
  35. ncbi request reprint Sentinel lymph node biopsy in histologically ambiguous melanocytic tumors with spitzoid features (so-called atypical spitzoid tumors)
    Rajmohan Murali
    Sydney Melanoma Unit, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, 2050, Australia
    Ann Surg Oncol 15:302-9. 2008
    ..The current study evaluated the role of sentinel lymph node (SLN) biopsy in patients with such atypical spitzoid tumors...
  36. doi request reprint Expression of glucose-regulated stress protein GRP78 is related to progression of melanoma
    Liquing Zhuang
    Department of Anatomical Pathology, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Histopathology 54:462-70. 2009
    ..The aim of this study was to investigate its expression and role in the development and progression of human melanoma...
  37. ncbi request reprint New evidence for geographic variation in the role of human papillomavirus in tonsillar carcinogenesis
    Wei Li
    Sydney Head and Neck Cancer Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, Australia
    Pathology 39:217-22. 2007
    ..This study provides the first data on HPV in tonsillar cancers from Hong Kong...
  38. ncbi request reprint The role of cell cycle regulatory proteins in the pathogenesis of melanoma
    Wei Li
    The Sydney Melanoma Unit, Royal Prince Alfred Hospital, Camperdown, Australia
    Pathology 38:287-301. 2006
    ..However, large validation studies linked to comprehensive clinical follow up data are necessary to clarify the prognostic significance of cell cycle regulatory proteins in individual patients...
  39. ncbi request reprint Management of merkel cell carcinoma: the roles of lymphoscintigraphy, sentinel lymph node biopsy and adjuvant radiotherapy
    Ross E Warner
    Sydney Melanoma Unit, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, 2050, Australia
    Ann Surg Oncol 15:2509-18. 2008
    ..However, its optimal treatment is uncertain. In this study, we aimed to assess the roles of lymphoscintigraphy and sentinel node (SN) biopsy, as well as radiotherapy, in the treatment of MCC...
  40. ncbi request reprint Diagnosis of metastatic melanoma by fine-needle biopsy: analysis of 2,204 cases
    Rajmohan Murali
    Department of Anatomical Pathology, Sydney Cancer Centre, Australia
    Am J Clin Pathol 127:385-97. 2007
    ..FNB is a highly accurate, rapid, and cost-effective procedure for the diagnosis of metastatic melanoma and should be considered as the initial diagnostic procedure of choice in patients with melanoma with clinically suspected metastases...
  41. doi request reprint Synchronous and metachronous malignancies in patients with melanoma: a clinicopathologic study highlighting the role of fine-needle biopsy cytology and potential diagnostic pitfalls
    Caroline L Cooper
    Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia
    Melanoma Res 20:203-11. 2010
    ..Careful assessment of the FNB cytologic features and directed use of ancillary studies should enable accurate diagnosis in most cases and facilitate appropriate patient management...
  42. ncbi request reprint Pathologic review of negative sentinel lymph nodes in melanoma patients with regional recurrence: a clinicopathologic study of 1152 patients undergoing sentinel lymph node biopsy
    Ling Xi L Li
    Melanoma and Skin Cancer Research Institute, Sydney Melanoma Unit, Royal Prince Alfred Hospital, Camperdown, NWS, Australia
    Am J Surg Pathol 27:1197-202. 2003
    ....
  43. doi request reprint Dynamics of chemokine, cytokine, and growth factor serum levels in BRAF-mutant melanoma patients during BRAF inhibitor treatment
    James S Wilmott
    Melanoma Institute Australia, Sydney, New South Wales 2060, Australia
    J Immunol 192:2505-13. 2014
    ..Further studies are needed to determine if CXCL8 is predictive of response and to confirm the functions of these chemokine and cytokine in BRAF-mutant melanoma under BRAF inhibition. ..
  44. ncbi request reprint Disturbed protein-protein interaction networks in metastatic melanoma are associated with worse prognosis and increased functional mutation burden
    Sarah Jane Schramm
    Sydney Medical School, The University of Sydney at Westmead Millennium Institute for Medical Research, Sydney, NSW, Australia
    Pigment Cell Melanoma Res 26:708-22. 2013
    ..The disturbed regions of networks are therefore markers of clinically relevant, selectable tumor evolution in melanoma which may carry driver mutations. ..
  45. ncbi request reprint Antimony by ICP-MS as a marker for sentinel lymph nodes in melanoma patients
    Michael Dawson
    Department of Chemistry, Materials and Forensic Science, University of Technology, Sydney, 1 Broadway, Broadway, NSW 2007, Australia
    Analyst 128:217-9. 2003
    ..A sensitive, accurate and specific method for the analysis of antimony by ICP-MS is presented as a marker of the sentinel lymph node in melanoma patients...
  46. doi request reprint Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanoma
    James S Wilmott
    Melanoma Institute Australia, Sydney, NSW, Australia
    Clin Cancer Res 18:1386-94. 2012
    ..To evaluate the effects of treatment with the potent mutant BRAF inhibitors GSK2118436 or vemurafenib (PLX4720) on immune responses to metastatic melanoma in tissues taken before and after treatment...
  47. ncbi request reprint Use of multiple cytometric markers improves discrimination between benign and malignant melanocytic lesions: a study of DNA microdensitometry, karyometry, argyrophilic staining of nucleolar organizer regions and MIB1-Ki67 immunoreactivity
    Ling Xi L Li
    Melanoma and Skin Cancer Research Institute, Sydney Melanoma Unit and Department of Anatomical Pathology, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia
    Melanoma Res 13:581-6. 2003
    ..This may be of particular significance in the diagnosis of melanocytic lesions whose biological behaviour cannot be confidently predicted by their histological features using conventional microscopy...
  48. ncbi request reprint Reduced expression of p16 and p27 is correlated with tumour progression in cutaneous melanoma
    Amira Sanki
    Sydney Melanoma Unit, Sydney Cancer Centre, Department of Anatomical Pathology, Royal Prince Alfred Hospital, and Discipline of Surgery, University of Sydney, NSW, Australia
    Pathology 39:551-7. 2007
    ..To determine if the cyclin dependent kinase inhibitors (CDKIs) p16 and p27 show reduced expression in the progression from benign to malignant melanocytic tumours, and to correlate these findings with patient prognosis...
  49. doi request reprint Prognostic factors in cutaneous desmoplastic melanoma: a study of 252 patients
    Rajmohan Murali
    Diagnostic Oncology and Tissue Pathology, Royal Prince Alfred Hospital, Camperdown, Sydney, New South Wales, Australia
    Cancer 116:4130-8. 2010
    ..Primary melanomas either may be entirely desmoplastic or almost entirely desmoplastic (pure DM [pDM]) or may exhibit a desmoplastic component admixed with a nondesmoplastic component (combined DM [cDM])...
  50. ncbi request reprint The prognostic importance of tumor mitotic rate confirmed in 1317 patients with primary cutaneous melanoma and long follow-up
    Anne Brecht Francken
    Sydney Melanoma Unit, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Ann Surg Oncol 11:426-33. 2004
    ..Data for a large cohort of patients, now with extended follow-up, whose tumors had been assessed by Dr. McGovern were analyzed to reassess the independent prognostic value of TMR in primary localized, cutaneous melanoma...
  51. doi request reprint Incidence of new primary melanomas after diagnosis of stage III and IV melanoma
    Lisa Zimmer
    Lisa Zimmer and Dirk Schadendorf, University Hospital, University Duisburg Essen, Essen, Germany Lauren E Haydu, Alexander M Menzies, Richard A Scolyer, Richard F Kefford, John F Thompson, and Georgina V Long, Melanoma Institute Australia Alexander M Menzies, Richard A Scolyer, Richard F Kefford, and Georgina V Long, Sydney Medical School, The University of Sydney Richard A Scolyer and John F Thompson, Royal Prince Alfred Hospital Lauren E Haydu and John F Thompson, The University of Sydney John F Thompson, Mater Hospital, Sydney Richard F Kefford and Georgina V Long, Westmead Institute for Cancer Research, Westmead Hospital, Westmead, New South Wales, Australia
    J Clin Oncol 32:816-23. 2014
    ..We sought to determine the background incidence of spontaneous NPMs after a diagnosis of American Joint Committee on Cancer/International Union Against Cancer stage III or IV melanoma in patients not treated with a BRAF inhibitor...
  52. ncbi request reprint Intrapatient homogeneity of BRAFV600E expression in melanoma
    Alexander M Menzies
    Melanoma Institute Australia Discipline of Medicine Pathology Surgery, The University of Sydney Departments of Melanoma and Surgical Oncology Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital Department of Medicine, Westmead Hospital Westmead Institute for Cancer Research, Westmead Hospital The Kinghorn Cancer Centre, Garvan Institute of Medical Research St Vincent s Clinical School, University of New South Wales, Sydney, Australia
    Am J Surg Pathol 38:377-82. 2014
    ....
  53. doi request reprint Outcomes of atypical spitz tumors with chromosomal copy number aberrations and conventional melanomas in children
    Pedram Gerami
    Department of Dermatology Robert H Lurie Cancer Center Department of Pediatric Dermatology, Ann and Robert H Lurie Children s Hospital of Chicago, Feinberg School of Medicine, Northwestern University, Chicago Abbott Molecular Laboratories, Des Plaines, IL Departments of Pathology Dermatology, University of Michigan Medical Center, Ann Arbor, MI Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY Department of Pathology, University of Pennsylvania, Philadelphia, PA Department of Pathology, Section of Dermatopathology Department of Dermatology, The University of Texas MD Anderson Cancer Center, Houston, TX Department of Pathology and Laboratory Medicine, Dermatopathology, UCLA Medical Center, Los Angeles, CA Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, The University of Sydney, NSW, Australia
    Am J Surg Pathol 37:1387-94. 2013
    ..Characteristic chromosomal copy number aberrations may occur in specific subtypes of melanocytic neoplasms in children and may help with the classification and prognostication of these rare tumors. ..
  54. ncbi request reprint p16(INK) (4a) deficiency promotes DNA hyper-replication and genetic instability in melanocytes
    Carina Fung
    Westmead Institute for Cancer Research, The University of Sydney at Westmead Millennium Institute, Westmead Hospital, Westmead, NSW, Australia
    Pigment Cell Melanoma Res 26:236-46. 2013
    ..Thus, we propose that loss of p16(INK) (4a) facilitates tumourigenesis by promoting the proliferation of genetically unstable cells...
  55. ncbi request reprint Margins of excision and prognostic factors for cutaneous eyelid melanomas
    Varun Harish
    Department of Melanoma and Surgical Oncology, Royal Prince Alfred Hospital, Sydney, Australia
    J Plast Reconstr Aesthet Surg 66:1066-73. 2013
    ..No consensus exists regarding appropriate excision margins for these tumours. This study sought to determine whether excision margins influenced locoregional recurrence, and to identify prognostic factors for survival in these patients...
  56. doi request reprint BRAF mutation, NRAS mutation, and the absence of an immune-related expressed gene profile predict poor outcome in patients with stage III melanoma
    Graham J Mann
    The University of Sydney at Westmead Millennium Institute, Westmead, New South Wales, Australia
    J Invest Dermatol 133:509-17. 2013
    ..We conclude that the presence of BRAF mutation, NRAS mutation, and the absence of an immune-related expressed gene profile predict poor outcome in melanoma patients with macroscopic stage III disease...
  57. doi request reprint Increasing tumor thickness is associated with recurrence and poorer survival in patients with Merkel cell carcinoma
    Cathy S Lim
    Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Ann Surg Oncol 19:3325-34. 2012
    ..Clinical and pathologic factors associated with disease progression and mortality in patients with MCC are poorly defined. Recently, it has been reported that p63 expression in primary MCC is strongly associated with clinical outcome...
  58. ncbi request reprint Distinguishing clinicopathologic features of patients with V600E and V600K BRAF-mutant metastatic melanoma
    Alexander M Menzies
    Melanoma Institute Australia, Disciplines of Medicine, Surgery, Pathology, and Westmead Institute for Cancer Research, Westmead Millennium Institute, The University of Sydney, Sydney, New South Wales, Australia
    Clin Cancer Res 18:3242-9. 2012
    ..This study sought to determine the BRAF mutation status by age-decade and whether BRAF-mutant genotypes correlated with clinicopathologic features and outcome in patients with metastatic melanoma...
  59. doi request reprint Desmoplastic neurotropic melanoma: a clinicopathologic analysis of 128 cases
    James Y Chen
    Department of Radiation Oncology, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Cancer 113:2770-8. 2008
    ..The authors investigated the local recurrence rates for patients with DNM after surgery alone or surgery followed by radiotherapy (RT)...
  60. doi request reprint Clinical and pathological features of metastases of primary cutaneous desmoplastic melanoma
    Rajmohan Murali
    Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Histopathology 58:886-95. 2011
    ..Our aim was to describe the histological features of metastases of primary DM and to determine whether they were predictive of outcome...
  61. ncbi request reprint Sentinel lymph node biopsy for melanoma: aspects of pathologic assessment
    Rajmohan Murali
    Royal Prince Alfred Hospital, Department of Anatomical Pathology, Camperdown, Sydney, NSW 2050, Australia
    Future Oncol 4:535-51. 2008
    ..Several non-histopathologic methods of SLN evaluation have been investigated, and while some of them show promise for the future, excision and histopathologic examination currently remains the gold standard for the evaluation of SLNs...
  62. ncbi request reprint Differentiating benign nevi from malignant melanoma using DNA microdensitometry and karyometry and maturation: a zonal comparison, correlation and multivariate analysis
    Ling Xi L Li
    Melanoma and Skin Cancer Research Institute, and Department of Anatomical Pathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Anal Quant Cytol Histol 24:234-43. 2002
    ..To evaluate the diagnostic effectiveness of cytometric features of DNA microdensitometry, karyometry (nuclear morphometry) and maturation and their combinations in separating benign nevi from malignant melanomas...
  63. doi request reprint Factors predicting recurrence and survival in sentinel lymph node-positive melanoma patients
    Rajmohan Murali
    Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Ann Surg 253:1155-64. 2011
    ..We investigated in detail the influence of SN tumor characteristics and clinical and primary tumor parameters on clinical outcomes in a large cohort of patients treated in a single center...
  64. doi request reprint Interobserver variation in the histopathologic reporting of key prognostic parameters, particularly clark level, affects pathologic staging of primary cutaneous melanoma
    Rajmohan Murali
    Department of Anatomical Pathology, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia
    Ann Surg 249:641-7. 2009
    ..However, detailed quantification of the magnitude of variation between observers and its effect on melanoma staging has not been reported...
  65. ncbi request reprint The history and future of melanoma staging
    John F Thompson
    Sydney Melanoma Unit, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    J Surg Oncol 86:224-35. 2004
    ..A further advantage would be that because there would be a direct link between staging and prognostic estimate, such a system would be more readily able to be understood in an intuitive fashion...
  66. doi request reprint The impact of in vivo reflectance confocal microscopy on the diagnostic accuracy of lentigo maligna and equivocal pigmented and nonpigmented macules of the face
    Pascale Guitera
    Sydney Melanoma Diagnostic Centre and Dermatology Department, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    J Invest Dermatol 130:2080-91. 2010
    ..In a test set of 29 LMs and 44 BMs, the OR for LM was 60.7 (confidence interval: 11.9-309) (93% sensitivity, 82% specificity)...
  67. doi request reprint p16 and pRb immunohistochemical expression increases with increasing tumour grade in mammary phyllodes tumours
    Rooshdiya Z Karim
    Department of Anatomical Pathology, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Histopathology 56:868-75. 2010
    ....
  68. pmc Absence of human papillomavirus in tonsillar squamous cell carcinomas from Chinese patients
    Wei Li
    Sydney Head and Neck Cancer Institute, Royal Prince Alfred Hospital, Sydney, Australia
    Am J Pathol 163:2185-9. 2003
    ..They also support the hypothesis that molecular pathways to tonsil cancer mediated by HPV are distinct from those induced by mutagens present in cigarette smoke or alcohol...
  69. doi request reprint In vivo confocal microscopy for diagnosis of melanoma and basal cell carcinoma using a two-step method: analysis of 710 consecutive clinically equivocal cases
    Pascale Guitera
    Department of Dermatology, Sydney Melanoma Diagnostic Centre, Royal Prince Alfred Hospital, University of Sydney, Sydney, Australia
    J Invest Dermatol 132:2386-94. 2012
    ..RCM is a highly accurate non-invasive technique for BCC diagnosis. Good diagnostic accuracy was achieved also for MM diagnosis, although rare variants of melanocytic tumors may limit the strict application of the algorithm...
  70. ncbi request reprint Absence of distinguishing senescence traits in human melanocytic nevi
    Sieu L Tran
    Westmead Institute for Cancer Research, University of Sydney at Westmead Millennium Institute, Westmead Hospital, Westmead, New South Wales, Australia
    J Invest Dermatol 132:2226-34. 2012
    ..We conclude that on the basis of current evidence it cannot be reasonably inferred that nevi are permanently growth arrested via senescence...
  71. pmc Interobserver reproducibility of histologic parameters of melanoma deposits in sentinel lymph nodes: implications for management of patients with melanoma
    Rajmohan Murali
    Department of Anatomical Pathology, Royal Prince Alfred Hospital, Sydney, Australia
    Cancer 115:5026-37. 2009
    ....
  72. ncbi request reprint Diagnostic value of 8.5 T magnetic resonance spectroscopy of benign and malignant skin lesion biopsies
    Pascale Guitera
    Sydney Melanoma Unit, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Melanoma Res 20:311-7. 2010
    ....
  73. doi request reprint Prognostic and clinicopathologic associations of oncogenic BRAF in metastatic melanoma
    Georgina V Long
    Melanoma Institute Australia, 40 Rocklands Rd, North Sydney, New South Wales, 2060, Australia
    J Clin Oncol 29:1239-46. 2011
    ..To assess the frequency and type of oncogenic BRAF mutations in metastatic melanoma and correlate BRAF status with clinicopathologic features and outcome...
  74. ncbi request reprint The complex relationships between sentinel node positivity, patient age, and primary tumor desmoplasia: analysis of 2303 melanoma patients treated at a single center
    Sander Sassen
    Sydney Melanoma Unit, Sydney Cancer Centre, Gloucester House, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia
    Ann Surg Oncol 15:630-7. 2008
    ..In addition, desmoplastic melanomas are associated with a lower frequency of SN positivity, although this is less well documented...
  75. ncbi request reprint Micromorphometric features of positive sentinel lymph nodes predict involvement of nonsentinel nodes in patients with melanoma
    Richard A Scolyer
    Melanoma and Skin Cancer Research Institute, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Am J Clin Pathol 122:532-9. 2004
    ..05). Our results indicate that some morphologic features of melanoma metastases in SLNs predict the likelihood of further nodal involvement in CLND specimens...
  76. ncbi request reprint Selective sentinel lymphadenectomy: progress to date and prospects for the future
    John F Thompson
    Sydney Melanoma Unit, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, NSW, 2050, Australia
    Cancer Treat Res 127:269-87. 2005
    ....
  77. ncbi request reprint Melanoma - a management guide for GPs
    John F Thompson
    Surgery Melanoma and Surgical Oncology, University of Sydney, Melanoma Institute Australia and Department of Melanoma and Surgical Oncology, Royal Prince Alfred Hospital, New South Wales
    Aust Fam Physician 41:470-3. 2012
    ..The incidence of melanoma in Australia continues to rise. Early diagnosis and management before the melanoma has metastasised provides the best opportunity for a favourable outcome...
  78. doi request reprint Treatment and prognostic significance of positive interval sentinel nodes in patients with primary cutaneous melanoma
    Nick Verwer
    Melanoma Institute Australia, Sydney, Australia
    Ann Surg Oncol 18:3292-9. 2011
    ..In this study, the incidence, location, and treatment of interval SNs in melanoma patients were analyzed to develop recommendations regarding the treatment of patients with interval SNs...
  79. ncbi request reprint Ultrasound examination of sentinel nodes in the initial assessment of patients with primary cutaneous melanoma
    Emma C Starritt
    Sydney Melanoma Unit, Sydney Cancer Centre and Melanoma and Skin Cancer Research Institute, Royal Prince Alfred Hospital, Camperdown, New South Wales, 2050, Australia
    Ann Surg Oncol 12:18-23. 2005
    ..The aim of this study was to determine the threshold size of metastatic melanoma deposits in SLNs able to be detected by targeted US examination before initial melanoma surgery...
  80. doi request reprint The prognostic value of tumor mitotic rate and other clinicopathologic factors in patients with locoregional recurrences of melanoma
    Rajmohan Murali
    Royal Prince Alfred Hospital, Sydney, Camperdown, NSW, Australia
    Ann Surg Oncol 17:2992-9. 2010
    ..In this study, we sought to determine the prognostic value of MRR and other clinicopathologic factors in recurrent melanoma...
  81. pmc Correlation between preoperative lymphoscintigraphy and metastatic nodal disease sites in 362 patients with cutaneous melanomas of the head and neck
    Johannes H W de Wilt
    Sydney Melanoma Unit and the Melanoma and Skin Cancer Research Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, New South Wales, Australia
    Ann Surg 239:544-52. 2004
    ..To assess the clinical relevance of these discordant node fields, the lymphoscintigrams of patients with head and neck melanomas were analyzed and correlated with the sites of metastatic nodal disease...
  82. ncbi request reprint Sentinel node biopsy for melanoma: Where have we been and where are we going?
    John F Thompson
    Sydney Melanoma Unit and the Melanoma and Skin Cancer Research Institute, Royal Prince Alfred Hospital, New South Wales, Australia
    Ann Surg Oncol 11:147S-51S. 2004
    ..Techniques such as in vivo proton magnetic resonance spectroscopy hold great promise and suggest that this goal might be achievable...
  83. ncbi request reprint Melanoma metastases in regional lymph nodes are accurately detected by proton magnetic resonance spectroscopy of fine-needle aspirate biopsy samples
    Jonathan R Stretch
    Sydney Melanoma Unit and Melanoma and Skin Cancer Research Institute, Royal Prince Alfred Hospital, Camperdown, New South Wales 2050, Australia
    Ann Surg Oncol 12:943-9. 2005
    ..This study was undertaken to determine the accuracy of the MRS method and thereby establish a basis for the future development of a nonsurgical technique for assessing SNs...
  84. doi request reprint Non-Sentinel Node Risk Score (N-SNORE): a scoring system for accurately stratifying risk of non-sentinel node positivity in patients with cutaneous melanoma with positive sentinel lymph nodes
    Rajmohan Murali
    Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    J Clin Oncol 28:4441-9. 2010
    ..We investigated clinicopathologic factors that predict NSN positivity in an attempt to identify patients who may be safely spared completion lymph node dissection (CLND)...
  85. ncbi request reprint Angiotropism is an independent predictor of local recurrence and in-transit metastasis in primary cutaneous melanoma
    Simone L Van Es
    Department of Anatomical Pathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Am J Surg Pathol 32:1396-403. 2008
    ..Our findings support the hypothesis that angiotropism represents a pathogenic mechanism for metastasis in patients with PCM...
  86. ncbi request reprint Myxoid variant of adrenocortical carcinoma: report of a unique case
    Rooshdiya Z Karim
    Department of Anatomical Pathology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Pathol Int 56:89-94. 2006
    ..Clinicoradiological correlation may be helpful, but special stains, immunohistochemistry and ultrastructural examination may be necessary to establish the diagnosis...
  87. doi request reprint Histologically ambiguous ("borderline") primary cutaneous melanocytic tumors: approaches to patient management including the roles of molecular testing and sentinel lymph node biopsy
    Richard A Scolyer
    Melanoma Institute Australia, Sydney, NSW, Australia
    Arch Pathol Lab Med 134:1770-7. 2010
    ....
  88. ncbi request reprint Surgical management of primary cutaneous melanoma: excision margins and the role of sentinel lymph node examination
    John F Thompson
    Sydney Melanoma Unit, Level 3, Gloucester House, Sydney Cancer Centre, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2006, Australia
    Surg Oncol Clin N Am 15:301-18. 2006
    ..Minimally invasive and noninvasive methods of SN assessment, such as magnetic resonance spectroscopy, are being evaluated...
  89. ncbi request reprint Fine-needle biopsy of metastatic melanoma: clinical use and new applications
    Rajmohan Murali
    Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Lancet Oncol 11:391-400. 2010
    ..In this review, the role of FNB as an important diagnostic modality in the management of suspected metastatic melanoma is described and other diagnostic and research applications of FNB are discussed...
  90. ncbi request reprint Quality of histopathological reporting on melanoma and influence of use of a synoptic template
    Lauren E Haydu
    The University of Sydney, Sydney, NSW, Australia
    Histopathology 56:768-74. 2010
    ....
  91. ncbi request reprint Elemental bio-imaging of melanoma in lymph node biopsies
    Dominic Hare
    Elemental Bio imaging Facility, University of Technology, Department of Chemistry and Forensic Science, Sydney, Broadway, New South Wales, Australia
    Analyst 134:450-3. 2009
    ..Further enhancement of the tumour boundary was achieved by imaging the (31)P/(34)S ratio. (31)P/(66)Zn ratio images showed a decreasing ratio beyond the tumour boundary that extended into peritumour normal lymph node tissue...
  92. ncbi request reprint Spitz naevus versus Spitzoid melanoma: when and how can they be distinguished?
    Kerry A Crotty
    Department of Anatomical Pathology, Melanoma and Skin Cancer Research Institute, Sydney, NSW, Australia
    Pathology 34:6-12. 2002
    ..This report highlights these new data and speculates on their possible future role in the diagnosis of borderline lesions...
  93. ncbi request reprint Cutaneous melanoma
    John F Thompson
    Sydney Melanoma Unit, University of Sydney at Royal Prince Alfred Hospital, Sydney, Camperdown, New South Wales, Australia
    Lancet 365:687-701. 2005
    ....
  94. ncbi request reprint Melanin bleaching in argyrophilic staining of AgNORs in pigmented lesions: a morphometric evaluation
    Ling Xi L Li
    Melanoma and Skin Cancer Research Institute, Department of Anatomical Pathology, Royal Prince Alfred Hospital, Camperdown, Australia
    Anal Quant Cytol Histol 24:166-72. 2002
    ..To establish a procedure that can effectively bleach melanin from pigmented lesions without affecting quantification of argyrophilic staining of nucleolar organizer regions (AgNORs)...
  95. doi request reprint Diagnosis of cutaneous melanocytic tumours by four-colour fluorescence in situ hybridisation
    Adrienne L Morey
    Department of Anatomical Pathology, St Vincent s Hospital, Darlinghurst, NSW, Australia
    Pathology 41:383-7. 2009
    ..We performed four-colour fluorescence in situ hybridisation (FISH) analysis of melanocytic tumours to determine the accuracy of the technique in classifying melanocytic tumours as benign or malignant...
  96. ncbi request reprint Histological expression of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) in human primary melanoma
    Luc P Bron
    Sydney Head and Neck Cancer Institute, Royal Prince Alfred Hospital, Sydney, Australia
    Pathology 36:561-5. 2004
    ..This study was designed to attempt to clarify the role of TRAIL in the biology of human melanoma...
  97. ncbi request reprint Cytoplasmic expression of nm23 predicts the potential for cerebral metastasis in patients with primary cutaneous melanoma
    Maria Sarris
    Neuroscience Institute of Schizophrenia and Allied Disorders, Darlinghurst, New South Wales, Australia
    Melanoma Res 14:23-7. 2004
    ..Patients with cutaneous melanomas with a low expression of nm23 appear to be more at risk of developing brain metastases...
  98. ncbi request reprint Increased expression of apoptotic markers in melanoma
    Michael Slater
    Institute for Biomedical Research, Department of Anatomy and Histology, The University of Sydney, Sydney, NSW 2006, Australia
    Melanoma Res 13:137-45. 2003
    ..In addition, keratinocyte regulation of the epidermis and dermis is severely compromised by the loss of E-cadherin and P2X(1-3) and P2Y(2) receptors, resulting in a lesion that is aggressive and malignant...
  99. doi request reprint Sentinel node positive melanoma patients: prediction and prognostic significance of nonsentinel node metastases and development of a survival tree model
    Martin Wiener
    Melanoma Institute Australia formerly Sydney Melanoma Unit, Sydney, NSW, Australia
    Ann Surg Oncol 17:1995-2005. 2010
    ..This study aimed to establish whether NSN status can be predicted, to determine its effect on survival, and to develop survival tree models for the sentinel node (SN) positive population...
  100. ncbi request reprint Frontiers in melanocytic pathology
    Richard A Scolyer
    Pathology 36:385-6. 2004
  101. ncbi request reprint Test and teach. Diagnosis: Subcutaneous Rosai-Dorfman disease
    Rooshdiya Karim
    Department of Anatomical Pathology, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Pathology 34:466-70. 2002