Research Topics
| Paul M MiddletonSummaryAffiliation: New South Wales Country: Australia Publications
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Detail Information
Publications
Relationship between the population incidence of febrile convulsions in young children in Sydney, Australia and seasonal epidemics of influenza and respiratory syncytial virus, 2003-2010: a time series analysisBenjamin G Polkinghorne
Public Health Officer Training Program, New South Wales Ministry of Health, Miller Street, North Sydney, 2059, Australia
BMC Infect Dis 11:291. 2011....
Fingertip photoplethysmographic waveform variability and systemic vascular resistance in intensive care unit patientsPaul M Middleton
Ambulance Research Institute, Ambulance Service of New South Wales, Sydney, NSW 2039, Australia
Med Biol Eng Comput 49:859-66. 2011....- Effectiveness of morphine, fentanyl, and methoxyflurane in the prehospital settingPaul M Middleton
The Ambulance Research Institute PMM, PMS, gs, JCB, Ambulance Service of NSW, Rozelle, New South Wales, Australia
Prehosp Emerg Care 14:439-47. 2010..To compare the effectiveness of intravenous (IV) morphine, intranasal (IN) fentanyl, and inhaled methoxyflurane when administered by paramedics to patients with moderate to severe pain... - Identification of high-risk acute coronary syndromes by spectral analysis of ear photoplethysmographic waveform variabilityPaul M Middleton
Ambulance Research Institute, Ambulance Service of New South Wales, Rozelle, Sydney, NSW 2039, Australia
Physiol Meas 32:1181-92. 2011..93. The results demonstrate the potential use of ear PPG waveform to identify high-risk heart disease patients, and further highlight the utility of frequency spectrum analysis of PPGV in critical care... - Noninvasive hemodynamic monitoring in the emergency departmentP M Middleton
Ambulance Research Institute, Ambulance Service of New South Wales, Sydney, Australia
Curr Opin Crit Care 17:342-50. 2011..This review analyses recent literature, which describes innovation in the range of noninvasive monitoring tools and places them in the emergency medicine context... - Peripheral photoplethysmography variability analysis of sepsis patientsPaul M Middleton
Prince of Wales Clinical School, University of New South Wales, Kensington, NSW, 2031, Australia
Med Biol Eng Comput 49:337-47. 2011..The study highlighted the value of PPG spectral analysis in the non-invasive assessment of peripheral vascular regulation in sepsis patients, with potential implications in monitoring the progression of sepsis... - Changes in left ventricular ejection time and pulse transit time derived from finger photoplethysmogram and electrocardiogram during moderate haemorrhagePaul M Middleton
Emergency Department, Prince of Wales Hospital, Sydney, NSW, Australia
Clin Physiol Funct Imaging 29:163-9. 2009.... - Spectral analysis of finger photoplethysmographic waveform variability in a model of mild to moderate haemorrhagePaul M Middleton
Emergency Department, Prince of Wales Hospital, Sydney, NSW, Australia
J Clin Monit Comput 22:343-53. 2008.... - Changes in the spectral powers of finger photoplethysmographic waveform variability in hemodialysis patientsFaizan Javed
School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, NSW, 2052, Australia
Conf Proc IEEE Eng Med Biol Soc 2009:3999-4002. 2009.... - Multivariate classification of systemic vascular resistance using photoplethysmographyQim Y Lee
Biomedical Systems Laboratory, School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, NSW 2052, Australia
Physiol Meas 32:1117-32. 2011..The results highlight the feasibility of deploying a multivariate statistical approach of SVR classification in the clinical setting, simply using a non-invasive and easy-to-measure PPG waveform signal... - RBF kernel based support vector regression to estimate the blood volume and heart rate responses during hemodialysisFaizan Javed
School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, NSW, 2052, Australia
Conf Proc IEEE Eng Med Biol Soc 2009:4352-5. 2009..4) compared to linear regression (AMSE=1.8 and 1.5). SVR also provided a better fit for HR with RBV for both training as well as testing data (AMSE=15.8 and 16.4) compared to linear regression (AMSE=25.2 and 20.1)... - Assessing the blood volume and heart rate responses during haemodialysis in fluid overloaded patients using support vector regressionFaizan Javed
School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, NSW 2052, Australia
Physiol Meas 30:1251-66. 2009..These modelled curves can be used as references to a controller that can be designed to regulate the haemodynamic variables to ensure the stability of patients undergoing haemodialysis... - Augmented photoplethysmographic low frequency waves at the onset of endotoxic shock in rabbitsGregory S H Chan
Biomedical Systems Laboratory, School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, NSW 2052, Australia
Physiol Meas 31:1605-21. 2010..01, HYPO1 versus EDTX1). The results demonstrate the value of PPGV in characterizing regional vascular control and provide important insights into the physiological mechanisms of endotoxic shock... - Pulse transit time variability analysis in an animal model of endotoxic shockCollin H H Tang
School of Electrical Engineering and Telecommunications, UNSW, Sydney, NSW 2052, Australia
Conf Proc IEEE Eng Med Biol Soc 2010:2849-52. 2010..84 with phase shift less than one cardiac beat). These results highlighted the potential value of PTT and its respiratory variation in characterizing the pathophysioloigcal hemodynamic change in endotoxic shock... 
Automatic detection of left ventricular ejection time from a finger photoplethysmographic pulse oximetry waveform: comparison with Doppler aortic measurementGregory S H Chan
Biomedical Systems Laboratory, School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, NSW, 2052, Australia
Physiol Meas 28:439-52. 2007..More extensive investigation is necessary to evaluate the applicability of the present approach in clinical care monitoring...- Detecting change in left ventricular ejection time during head-up tilt-induced progressive central hypovolemia using a finger photoplethysmographic pulse oximetry wave formGregory S H Chan
Biomedical Systems Laboratory, School of Electrical Engineering and Telecommunications, Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia
J Trauma 64:390-7. 2008.... - Frequency spectrum analysis of finger photoplethysmographic waveform variability during haemodialysisFaizan Javed
School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, NSW 2052, Australia
Physiol Meas 31:1203-16. 2010.... - Change in pulse transit time and pre-ejection period during head-up tilt-induced progressive central hypovolaemiaGregory S H Chan
Biomedical Systems Laboratory, School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, NSW 2052, Australia
J Clin Monit Comput 21:283-93. 2007.... - Spontaneous fluctuations in the peripheral photoplethysmographic waveform: roles of arterial pressure and muscle sympathetic nerve activityGregory S H Chan
1School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, New South Wales
Am J Physiol Heart Circ Physiol 302:H826-36. 2012..Spontaneous PPG variability in the ear includes a major contribution from arterial pressure and MSNA, which may provide a rationale for its clinical utility... - Non-invasive classification of severe sepsis and systemic inflammatory response syndrome using a nonlinear support vector machine: a preliminary studyCollin H H Tang
School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, NSW 2052, Australia
Physiol Meas 31:775-93. 2010.... - Respiration-induced changes in ear photoplethysmography relates to relative blood volume during hemodialysisFaizan Javed
School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, 2052, Australia
Conf Proc IEEE Eng Med Biol Soc 2010:859-62. 2010..64, p 〈 0.05). This study suggests that ear PPG may be a suitable monitor of the systemic circulation and can provide a non-invasive tool to detect blood volume loss... - Model predictive control of relative blood volume and heart rate during hemodialysisFaizan Javed
School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, NSW, Australia
Med Biol Eng Comput 48:389-97. 2010..The results show that adjusting UFR may improve the stability of patient during dialysis when compared to conventional hemodialysis with constant UFR... - Prehospital vital signs can predict pain severity: analysis using ordinal logistic regressionJason C Bendall
Ambulance Research Institute, Ambulance Service of New South Wales, Rozelle, Australia
Eur J Emerg Med 18:334-9. 2011..To determine whether vital signs in patients suffering from acute pain in the out-of-hospital setting have any association with pain severity measured using an ordinal pain scale... - Transfer function analysis of baroreflex function in a rabbit model of endotoxic shockCollin H H Tang
School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, NSW 2052, Australia
Conf Proc IEEE Eng Med Biol Soc 2009:1848-51. 2009.... - Classification of low systemic vascular resistance using photoplethysmogram and routine cardiovascular measurementsQim Y Lee
Biomedical Systems Laboratory, School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, 2052, Australia
Conf Proc IEEE Eng Med Biol Soc 2010:1930-3. 2010..43) alone showed inferior performance. Discrimination of patients with and without low SVR can be achieved with reasonable accuracy using multiple features derived from the PPG combined with routine cardiovascular measurements... - Effectiveness of prehospital morphine, fentanyl, and methoxyflurane in pediatric patientsJason C Bendall
Ambulance Research Institute, Ambulance Service of NSW, Rozelle, New South Wales, Australia
Prehosp Emerg Care 15:158-65. 2011..To compare the effectiveness of intravenous morphine, intranasal (IN) fentanyl, and inhaled methoxyflurane for managing moderate to severe pain in pediatric patients in the out-of-hospital setting... - Prehospital analgesia in New South Wales, AustraliaJason C Bendall
Ambulance Research Institute, Ambulance Service of New South Wales, Rozelle NSW, Australia
Prehosp Disaster Med 26:422-6. 2011..The objective of this study was to describe the use of intravenous morphine, inhaled methoxyflurane, and intranasal fentanyl when administered in the out-of-hospital setting by paramedics within a large Australian ambulance service... - Photoplethysmographic variability analysis in critical care--current progress and future challengesGregory S H Chan
School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, NSW 2052, Australia
Conf Proc IEEE Eng Med Biol Soc 2011:5507-10. 2011.... - Spectral analysis of heart period and pulse transit time derived from electrocardiogram and photoplethysmogram in sepsis patientsCollin H H Tang
School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, NSW 2052, Australia
Conf Proc IEEE Eng Med Biol Soc 2009:1781-4. 2009..The results have highlighted the potential value of spectral analysis of RRi and PTT variabilities as a non-invasive tool for clinical evaluation of cardiac autonomic regulation in sepsis patients... - Beliefs and expectations of paramedics towards evidence-based practice and researchPaul M Simpson
Ambulance Service of New South Wales Biostatistical Training Program, New South Wales Department of Health, Sydney, New South Wales, Australia
Int J Evid Based Healthc 10:197-203. 2012..The objective of this cross-sectional online survey was to better understand the beliefs of paramedics towards research and evidence-based practice and their expectations regarding its impact on their ability to provide patient care... - Review article: Prophylactic metoclopramide for patients receiving intravenous morphine in the emergency setting: a systematic review and meta-analysis of randomized controlled trialsPaul M Simpson
Ambulance Research Institute, Ambulance Service of New South Wales, Rozelle, New South Wales, Australia
Emerg Med Australas 23:452-7. 2011..v. morphine for acute pain management in the emergency setting is clinically beneficial. Routine metoclopramide administration might expose patients to a risk of harm which is not justifiable given a lack of evidence of benefit... - Characteristics of fall-related injuries attended by an ambulance in Sydney, Australia: a surveillance summarySusan L Thomas
NSW Public Health Officer Training Program, NSW Department of Health, Australia
N S W Public Health Bull 22:49-54. 2011..Expansion of data linkage to emergency department and admitted patient databases would provide information to further describe the epidemiology of falls in NSW... - Paramedic-performed digital nerve block to facilitate field reduction of a dislocated fingerPaul M Simpson
Ambulance Service of New South Wales, New South Wales, Australia
Prehosp Emerg Care 16:415-7. 2012..With appropriate training, prehospital digital nerve blocks may be a feasible option to supplement existing paramedic analgesic options... - Do clinical safety charts improve paramedic key performance indicator results? (A clinical improvement programme evaluation)Phillip Ebbs
Ambulance Service of NSW, 1 Central Road, Port Macquarie, NSW 2444, Australia
Emerg Med J 29:596-7. 2012..Is the Clinical Safety Chart clinical improvement programme (CIP) effective at improving paramedic key performance indicator (KPI) results within the Ambulance Service of New South Wales?.. - An investigation into the cost, coverage and activities of Helicopter Emergency Medical Services in the state of New South Wales, AustraliaColman B Taylor
The George Institute for Global Health, Camperdown, NSW, 2050, Australia
Injury 42:1088-94. 2011..The aim of this study was to assess the cost of HEMS in NSW and investigate the factors linked with the variation in the costs, coverage and activities of HEMS... - The rural Prehospital Acute Stroke Triage (PAST) trial protocol: a controlled trial for rapid facilitated transport of rural acute stroke patients to a regional stroke centreAshley R Garnett
Stroke Program, Centre for Brain and Mental Health Research, John Hunter Hospital, University of Newcastle and Hunter Medical Research Institute, Lookout Road, New Lambton Heights 2305, NSW, Australia
Int J Stroke 5:506-13. 2010..The trial has relevance to stroke clinicians, health service managers and planners responsible for rural populations...