Paul M Middleton

Summary

Affiliation: New South Wales
Country: Australia

Publications

  1. pmc Relationship between the population incidence of febrile convulsions in young children in Sydney, Australia and seasonal epidemics of influenza and respiratory syncytial virus, 2003-2010: a time series analysis
    Benjamin G Polkinghorne
    Public Health Officer Training Program, New South Wales Ministry of Health, Miller Street, North Sydney, 2059, Australia
    BMC Infect Dis 11:291. 2011
  2. doi request reprint Fingertip photoplethysmographic waveform variability and systemic vascular resistance in intensive care unit patients
    Paul M Middleton
    Ambulance Research Institute, Ambulance Service of New South Wales, Sydney, NSW 2039, Australia
    Med Biol Eng Comput 49:859-66. 2011
  3. doi request reprint Effectiveness of morphine, fentanyl, and methoxyflurane in the prehospital setting
    Paul M Middleton
    The Ambulance Research Institute PMM, PMS, gs, JCB, Ambulance Service of NSW, Rozelle, New South Wales, Australia
    Prehosp Emerg Care 14:439-47. 2010
  4. doi request reprint Identification of high-risk acute coronary syndromes by spectral analysis of ear photoplethysmographic waveform variability
    Paul M Middleton
    Ambulance Research Institute, Ambulance Service of New South Wales, Rozelle, Sydney, NSW 2039, Australia
    Physiol Meas 32:1181-92. 2011
  5. doi request reprint Noninvasive hemodynamic monitoring in the emergency department
    P M Middleton
    Ambulance Research Institute, Ambulance Service of New South Wales, Sydney, Australia
    Curr Opin Crit Care 17:342-50. 2011
  6. doi request reprint Peripheral photoplethysmography variability analysis of sepsis patients
    Paul M Middleton
    Prince of Wales Clinical School, University of New South Wales, Kensington, NSW, 2031, Australia
    Med Biol Eng Comput 49:337-47. 2011
  7. doi request reprint Changes in left ventricular ejection time and pulse transit time derived from finger photoplethysmogram and electrocardiogram during moderate haemorrhage
    Paul M Middleton
    Emergency Department, Prince of Wales Hospital, Sydney, NSW, Australia
    Clin Physiol Funct Imaging 29:163-9. 2009
  8. doi request reprint Spectral analysis of finger photoplethysmographic waveform variability in a model of mild to moderate haemorrhage
    Paul M Middleton
    Emergency Department, Prince of Wales Hospital, Sydney, NSW, Australia
    J Clin Monit Comput 22:343-53. 2008
  9. pmc Estimation of cardiac output and systemic vascular resistance using a multivariate regression model with features selected from the finger photoplethysmogram and routine cardiovascular measurements
    Qim Y Lee
    School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, NSW, Australia
    Biomed Eng Online 12:19. 2013
  10. doi request reprint Changes in the spectral powers of finger photoplethysmographic waveform variability in hemodialysis patients
    Faizan Javed
    School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, NSW, 2052, Australia
    Conf Proc IEEE Eng Med Biol Soc 2009:3999-4002. 2009

Collaborators

Detail Information

Publications39

  1. pmc Relationship between the population incidence of febrile convulsions in young children in Sydney, Australia and seasonal epidemics of influenza and respiratory syncytial virus, 2003-2010: a time series analysis
    Benjamin G Polkinghorne
    Public Health Officer Training Program, New South Wales Ministry of Health, Miller Street, North Sydney, 2059, Australia
    BMC Infect Dis 11:291. 2011
    ....
  2. doi request reprint Fingertip photoplethysmographic waveform variability and systemic vascular resistance in intensive care unit patients
    Paul M Middleton
    Ambulance Research Institute, Ambulance Service of New South Wales, Sydney, NSW 2039, Australia
    Med Biol Eng Comput 49:859-66. 2011
    ....
  3. doi request reprint Effectiveness of morphine, fentanyl, and methoxyflurane in the prehospital setting
    Paul M Middleton
    The Ambulance Research Institute PMM, PMS, gs, JCB, Ambulance Service of NSW, Rozelle, New South Wales, Australia
    Prehosp Emerg Care 14:439-47. 2010
    ..To compare the effectiveness of intravenous (IV) morphine, intranasal (IN) fentanyl, and inhaled methoxyflurane when administered by paramedics to patients with moderate to severe pain...
  4. doi request reprint Identification of high-risk acute coronary syndromes by spectral analysis of ear photoplethysmographic waveform variability
    Paul M Middleton
    Ambulance Research Institute, Ambulance Service of New South Wales, Rozelle, Sydney, NSW 2039, Australia
    Physiol Meas 32:1181-92. 2011
    ..93. The results demonstrate the potential use of ear PPG waveform to identify high-risk heart disease patients, and further highlight the utility of frequency spectrum analysis of PPGV in critical care...
  5. doi request reprint Noninvasive hemodynamic monitoring in the emergency department
    P M Middleton
    Ambulance Research Institute, Ambulance Service of New South Wales, Sydney, Australia
    Curr Opin Crit Care 17:342-50. 2011
    ..This review analyses recent literature, which describes innovation in the range of noninvasive monitoring tools and places them in the emergency medicine context...
  6. doi request reprint Peripheral photoplethysmography variability analysis of sepsis patients
    Paul M Middleton
    Prince of Wales Clinical School, University of New South Wales, Kensington, NSW, 2031, Australia
    Med Biol Eng Comput 49:337-47. 2011
    ..The study highlighted the value of PPG spectral analysis in the non-invasive assessment of peripheral vascular regulation in sepsis patients, with potential implications in monitoring the progression of sepsis...
  7. doi request reprint Changes in left ventricular ejection time and pulse transit time derived from finger photoplethysmogram and electrocardiogram during moderate haemorrhage
    Paul M Middleton
    Emergency Department, Prince of Wales Hospital, Sydney, NSW, Australia
    Clin Physiol Funct Imaging 29:163-9. 2009
    ....
  8. doi request reprint Spectral analysis of finger photoplethysmographic waveform variability in a model of mild to moderate haemorrhage
    Paul M Middleton
    Emergency Department, Prince of Wales Hospital, Sydney, NSW, Australia
    J Clin Monit Comput 22:343-53. 2008
    ....
  9. pmc Estimation of cardiac output and systemic vascular resistance using a multivariate regression model with features selected from the finger photoplethysmogram and routine cardiovascular measurements
    Qim Y Lee
    School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, NSW, Australia
    Biomed Eng Online 12:19. 2013
    ..In this study, a method is proposed to estimate both the CO and SVR of a heterogeneous cohort of intensive care unit patients (N=48)...
  10. doi request reprint Changes in the spectral powers of finger photoplethysmographic waveform variability in hemodialysis patients
    Faizan Javed
    School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, NSW, 2052, Australia
    Conf Proc IEEE Eng Med Biol Soc 2009:3999-4002. 2009
    ....
  11. doi request reprint Multivariate classification of systemic vascular resistance using photoplethysmography
    Qim Y Lee
    Biomedical Systems Laboratory, School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, NSW 2052, Australia
    Physiol Meas 32:1117-32. 2011
    ..The results highlight the feasibility of deploying a multivariate statistical approach of SVR classification in the clinical setting, simply using a non-invasive and easy-to-measure PPG waveform signal...
  12. doi request reprint RBF kernel based support vector regression to estimate the blood volume and heart rate responses during hemodialysis
    Faizan Javed
    School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, NSW, 2052, Australia
    Conf Proc IEEE Eng Med Biol Soc 2009:4352-5. 2009
    ..4) compared to linear regression (AMSE=1.8 and 1.5). SVR also provided a better fit for HR with RBV for both training as well as testing data (AMSE=15.8 and 16.4) compared to linear regression (AMSE=25.2 and 20.1)...
  13. ncbi request reprint Assessing the blood volume and heart rate responses during haemodialysis in fluid overloaded patients using support vector regression
    Faizan Javed
    School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, NSW 2052, Australia
    Physiol Meas 30:1251-66. 2009
    ..These modelled curves can be used as references to a controller that can be designed to regulate the haemodynamic variables to ensure the stability of patients undergoing haemodialysis...
  14. doi request reprint Augmented photoplethysmographic low frequency waves at the onset of endotoxic shock in rabbits
    Gregory S H Chan
    Biomedical Systems Laboratory, School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, NSW 2052, Australia
    Physiol Meas 31:1605-21. 2010
    ..01, HYPO1 versus EDTX1). The results demonstrate the value of PPGV in characterizing regional vascular control and provide important insights into the physiological mechanisms of endotoxic shock...
  15. doi request reprint Pulse transit time variability analysis in an animal model of endotoxic shock
    Collin H H Tang
    School of Electrical Engineering and Telecommunications, UNSW, Sydney, NSW 2052, Australia
    Conf Proc IEEE Eng Med Biol Soc 2010:2849-52. 2010
    ..84 with phase shift less than one cardiac beat). These results highlighted the potential value of PTT and its respiratory variation in characterizing the pathophysioloigcal hemodynamic change in endotoxic shock...
  16. doi request reprint Detecting change in left ventricular ejection time during head-up tilt-induced progressive central hypovolemia using a finger photoplethysmographic pulse oximetry wave form
    Gregory S H Chan
    Biomedical Systems Laboratory, School of Electrical Engineering and Telecommunications, Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia
    J Trauma 64:390-7. 2008
    ....
  17. doi request reprint Frequency spectrum analysis of finger photoplethysmographic waveform variability during haemodialysis
    Faizan Javed
    School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, NSW 2052, Australia
    Physiol Meas 31:1203-16. 2010
    ....
  18. ncbi request reprint Automatic detection of left ventricular ejection time from a finger photoplethysmographic pulse oximetry waveform: comparison with Doppler aortic measurement
    Gregory S H Chan
    Biomedical Systems Laboratory, School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, NSW, 2052, Australia
    Physiol Meas 28:439-52. 2007
    ..More extensive investigation is necessary to evaluate the applicability of the present approach in clinical care monitoring...
  19. ncbi request reprint Change in pulse transit time and pre-ejection period during head-up tilt-induced progressive central hypovolaemia
    Gregory S H Chan
    Biomedical Systems Laboratory, School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, NSW 2052, Australia
    J Clin Monit Comput 21:283-93. 2007
    ....
  20. doi request reprint Epidemiology of ambulance responses to older people who have fallen in New South Wales, Australia
    Paul M Simpson
    Ambulance Service of New South Wales, Sydney, New South Wales, Australia School of Public Health and Community Medicine, University of New South Wales, Sydney, New South Wales, Australia
    Australas J Ageing 32:171-6. 2013
    ..To quantify the size and scope of the operational burden for a large ambulance service arising from older people who have fallen and to describe this population...
  21. doi request reprint Spontaneous fluctuations in the peripheral photoplethysmographic waveform: roles of arterial pressure and muscle sympathetic nerve activity
    Gregory S H Chan
    1School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, New South Wales
    Am J Physiol Heart Circ Physiol 302:H826-36. 2012
    ..Spontaneous PPG variability in the ear includes a major contribution from arterial pressure and MSNA, which may provide a rationale for its clinical utility...
  22. doi request reprint Respiration-induced changes in ear photoplethysmography relates to relative blood volume during hemodialysis
    Faizan Javed
    School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, 2052, Australia
    Conf Proc IEEE Eng Med Biol Soc 2010:859-62. 2010
    ..64, p 〈 0.05). This study suggests that ear PPG may be a suitable monitor of the systemic circulation and can provide a non-invasive tool to detect blood volume loss...
  23. doi request reprint Model predictive control of relative blood volume and heart rate during hemodialysis
    Faizan Javed
    School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, NSW, Australia
    Med Biol Eng Comput 48:389-97. 2010
    ..The results show that adjusting UFR may improve the stability of patient during dialysis when compared to conventional hemodialysis with constant UFR...
  24. doi request reprint Non-invasive classification of severe sepsis and systemic inflammatory response syndrome using a nonlinear support vector machine: a preliminary study
    Collin H H Tang
    School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, NSW 2052, Australia
    Physiol Meas 31:775-93. 2010
    ....
  25. doi request reprint Prehospital vital signs can predict pain severity: analysis using ordinal logistic regression
    Jason C Bendall
    Ambulance Research Institute, Ambulance Service of New South Wales, Rozelle, Australia
    Eur J Emerg Med 18:334-9. 2011
    ..To determine whether vital signs in patients suffering from acute pain in the out-of-hospital setting have any association with pain severity measured using an ordinal pain scale...
  26. doi request reprint Transfer function analysis of baroreflex function in a rabbit model of endotoxic shock
    Collin H H Tang
    School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, NSW 2052, Australia
    Conf Proc IEEE Eng Med Biol Soc 2009:1848-51. 2009
    ....
  27. doi request reprint Classification of low systemic vascular resistance using photoplethysmogram and routine cardiovascular measurements
    Qim Y Lee
    Biomedical Systems Laboratory, School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, 2052, Australia
    Conf Proc IEEE Eng Med Biol Soc 2010:1930-3. 2010
    ..43) alone showed inferior performance. Discrimination of patients with and without low SVR can be achieved with reasonable accuracy using multiple features derived from the PPG combined with routine cardiovascular measurements...
  28. doi request reprint Effectiveness of prehospital morphine, fentanyl, and methoxyflurane in pediatric patients
    Jason C Bendall
    Ambulance Research Institute, Ambulance Service of NSW, Rozelle, New South Wales, Australia
    Prehosp Emerg Care 15:158-65. 2011
    ..To compare the effectiveness of intravenous morphine, intranasal (IN) fentanyl, and inhaled methoxyflurane for managing moderate to severe pain in pediatric patients in the out-of-hospital setting...
  29. ncbi request reprint Prehospital analgesia in New South Wales, Australia
    Jason C Bendall
    Ambulance Research Institute, Ambulance Service of New South Wales, Rozelle NSW, Australia
    Prehosp Disaster Med 26:422-6. 2011
    ..The objective of this study was to describe the use of intravenous morphine, inhaled methoxyflurane, and intranasal fentanyl when administered in the out-of-hospital setting by paramedics within a large Australian ambulance service...
  30. doi request reprint Photoplethysmographic variability analysis in critical care--current progress and future challenges
    Gregory S H Chan
    School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, NSW 2052, Australia
    Conf Proc IEEE Eng Med Biol Soc 2011:5507-10. 2011
    ....
  31. doi request reprint Spectral analysis of heart period and pulse transit time derived from electrocardiogram and photoplethysmogram in sepsis patients
    Collin H H Tang
    School of Electrical Engineering and Telecommunications, The University of New South Wales, Sydney, NSW 2052, Australia
    Conf Proc IEEE Eng Med Biol Soc 2009:1781-4. 2009
    ..The results have highlighted the potential value of spectral analysis of RRi and PTT variabilities as a non-invasive tool for clinical evaluation of cardiac autonomic regulation in sepsis patients...
  32. ncbi request reprint What causes adverse events in prehospital care? A human-factors approach
    Roger Price
    Ambulance Research Institute, Ambulance Service of New South Wales, Locked Bag 105, Rozelle, NSW 2039, Australia
    Emerg Med J 30:583-8. 2013
    ..We hypothesised that adverse patient events occurring during the prehospital phase may fall into discernible patterns, and that an understanding of these patterns would be valuable in the development of mitigation strategies...
  33. doi request reprint Beliefs and expectations of paramedics towards evidence-based practice and research
    Paul M Simpson
    Ambulance Service of New South Wales Biostatistical Training Program, New South Wales Department of Health, Sydney, New South Wales, Australia
    Int J Evid Based Healthc 10:197-203. 2012
    ..The objective of this cross-sectional online survey was to better understand the beliefs of paramedics towards research and evidence-based practice and their expectations regarding its impact on their ability to provide patient care...
  34. ncbi request reprint Review article: Prophylactic metoclopramide for patients receiving intravenous morphine in the emergency setting: a systematic review and meta-analysis of randomized controlled trials
    Paul M Simpson
    Ambulance Research Institute, Ambulance Service of New South Wales, Rozelle, New South Wales, Australia
    Emerg Med Australas 23:452-7. 2011
    ..v. morphine for acute pain management in the emergency setting is clinically beneficial. Routine metoclopramide administration might expose patients to a risk of harm which is not justifiable given a lack of evidence of benefit...
  35. doi request reprint Characteristics of fall-related injuries attended by an ambulance in Sydney, Australia: a surveillance summary
    Susan L Thomas
    NSW Public Health Officer Training Program, NSW Department of Health, Australia
    N S W Public Health Bull 22:49-54. 2011
    ..Expansion of data linkage to emergency department and admitted patient databases would provide information to further describe the epidemiology of falls in NSW...
  36. doi request reprint Paramedic-performed digital nerve block to facilitate field reduction of a dislocated finger
    Paul M Simpson
    Ambulance Service of New South Wales, New South Wales, Australia
    Prehosp Emerg Care 16:415-7. 2012
    ..With appropriate training, prehospital digital nerve blocks may be a feasible option to supplement existing paramedic analgesic options...
  37. doi request reprint Do clinical safety charts improve paramedic key performance indicator results? (A clinical improvement programme evaluation)
    Phillip Ebbs
    Ambulance Service of NSW, 1 Central Road, Port Macquarie, NSW 2444, Australia
    Emerg Med J 29:596-7. 2012
    ..Is the Clinical Safety Chart clinical improvement programme (CIP) effective at improving paramedic key performance indicator (KPI) results within the Ambulance Service of New South Wales?..
  38. doi request reprint An investigation into the cost, coverage and activities of Helicopter Emergency Medical Services in the state of New South Wales, Australia
    Colman B Taylor
    The George Institute for Global Health, Camperdown, NSW, 2050, Australia
    Injury 42:1088-94. 2011
    ..The aim of this study was to assess the cost of HEMS in NSW and investigate the factors linked with the variation in the costs, coverage and activities of HEMS...
  39. doi request reprint The rural Prehospital Acute Stroke Triage (PAST) trial protocol: a controlled trial for rapid facilitated transport of rural acute stroke patients to a regional stroke centre
    Ashley R Garnett
    Stroke Program, Centre for Brain and Mental Health Research, John Hunter Hospital, University of Newcastle and Hunter Medical Research Institute, Lookout Road, New Lambton Heights 2305, NSW, Australia
    Int J Stroke 5:506-13. 2010
    ..The trial has relevance to stroke clinicians, health service managers and planners responsible for rural populations...