Research Topics
Species | Anthony S McLeanSummaryAffiliation: New South Wales Country: Australia Publications
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Publications
The confounding effects of age, gender, serum creatinine, and electrolyte concentrations on plasma B-type natriuretic peptide concentrations in critically ill patientsAnthony S McLean
Department of Intensive Care Medicine, Nepean Hospital, University of Sydney, Penrith, NSW, Australia
Crit Care Med 31:2611-8. 2003..To investigate the confounding effects of age, gender, serum creatinine, and electrolyte concentrations on plasma B-type natriuretic peptide (BNP) concentrations in critically ill patients...
Duration of the beneficial effects of levosimendan in decompensated heart failure as measured by echocardiographic indices and B-type natriuretic peptideAnthony S McLean
Department of Intensive Care Medicine, University of Sydney, Nepean Hospital, Penrith, New South Wales 2750, Australia
J Cardiovasc Pharmacol 46:830-5. 2005..In conclusion, LS transiently improved the cardiac function, and the effects lasted for at least 7 days after discontinuation of infusion. Most effects, except LVEF, were not significantly different from baseline on day 30...
Accuracy of procalcitonin for sepsis diagnosis in critically ill patients: systematic review and meta-analysisBenjamin M P Tang
Department of Intensive Care Medicine, Nepean Hospital, Penrith, New South Wales, Australia
Lancet Infect Dis 7:210-7. 2007..The findings from this study do not lend support to the widespread use of the procalcitonin test in critical care settings...
Gene-expression profiling of gram-positive and gram-negative sepsis in critically ill patientsBenjamin M P Tang
Department of Intensive Care Medicine, Nepean Hospital and Western Clinical School, University of Sydney, Penrith, NSW 2750, Australia
Crit Care Med 36:1125-8. 2008..Using microarray technology, we compared the gene-expression profiles of gram-positive sepsis and gram-negative sepsis in critically ill patients...
Use of corticosteroids in acute lung injury and acute respiratory distress syndrome: a systematic review and meta-analysisBenjamin M P Tang
Department of Intensive Care Medicine, Nepean Hospital, Penrith, New South Wales, Australia
Crit Care Med 37:1594-603. 2009..We aimed to evaluate all studies investigating prolonged corticosteroids in low-to-moderate dose in ALI or ARDS...
Prognostic values of B-type natriuretic peptide in severe sepsis and septic shockAnthony S McLean
Department of Intensive Care Medicine, University of Sydney, Nepean Hospital, Sydney, NSW, Australia
Crit Care Med 35:1019-26. 2007..To investigate the changes in B-type natriuretic peptide concentrations in patients with severe sepsis and septic shock and to investigate the value of B-type natriuretic peptide in predicting intensive care unit outcomes...
Gene-expression profiling of peripheral blood mononuclear cells in sepsisBenjamin M P Tang
Department of Intensive Care Medicine, Nepean Hospital and Western Clinical School, University of Sydney, Penrith, NSW, Australia
Crit Care Med 37:882-8. 2009....
Bench-to-bedside review: the value of cardiac biomarkers in the intensive care patientAnthony S McLean
Department of Intensive Care Medicine, Nepean Hospital, University of Sydney, Sydney, NSW 2750, Australia
Crit Care 12:215. 2008..The present review summarizes the available biomarkers for different cardiac conditions. Potential biomarkers under evaluation are also briefly discussed...
The applications of B-type natriuretic peptide measurement in the intensive care unitAnthony S McLean
Department of Intensive Care Medicine, Nepean Hospital, University of Sydney, Sydney, Australia
Curr Opin Crit Care 11:406-12. 2005..This review summarizes the recent advances in the application of B-type natriuretic peptide measurement in the intensive care unit...
Genome-wide transcription profiling of human sepsis: a systematic reviewBenjamin M Tang
Department of Intensive Care Medicine, Nepean Hospital and Nepean Clinical School, University of Sydney, Penrith, NSW 2750, Australia
Crit Care 14:R237. 2010..We, therefore, synthesized current genomic studies that examined the host response of circulating leukocytes to human sepsis...
The use of the right ventricular diameter and tricuspid annular tissue Doppler velocity parameter to predict the presence of pulmonary hypertensionAnthony S McLean
Cardiovascular Ultrasound Laboratory, Department of Intensive Care Medicine, Nepean Hospital, University of Sydney, Great Western Highway, Penrith, NSW 2750, Australia
Eur J Echocardiogr 8:128-36. 2007..This however relies on the presence of tricuspid regurgitation (TR). We examined if the presence of PH can be predicted echocardiographically without relying on TR...
The use of gene-expression profiling to identify candidate genes in human sepsisBenjamin M P Tang
Department of Intensive Care Medicine, Nepean Hospital and Western Clinical School, University of Sydney, Penrith, Australia
Am J Respir Crit Care Med 176:676-84. 2007..Genomewide study offers an unbiased, system biology approach to examine the expression patterns of circulating leukocytes and may reveal novel insights into the host response to sepsis...
"Host tissue damage" signal ATP impairs IL-12 and IFNgamma secretion in LPS stimulated whole human bloodMarek Nalos
Department of Intensive Care, Nepean Hospital, University of Sydney, P O Box 63, Penrith, NSW 2750, Australia
Intensive Care Med 34:1891-7. 2008..We hypothesized that extracellular nucleotides in concentrations similar to those found near injured and ischemic tissues will modulate cytokine secretion...
Diagnoses of right-sided empyema complicating tricuspid valve endocarditis during transesophageal echocardiographyMarek Nalos
Department of Intensive Care Medicine, Nepean Hospital, University of Sydney, PO Box 63, Penrith NSW 2751, Australia
J Am Soc Echocardiogr 17:464-5. 2004..The simultaneous visualization of right-sided empyema, previously undiagnosed, by transesophageal echocardiography, led to operative treatment by thoracoscopy and right lung decortication...
Cardiovascular responses to short-term head-down positioning in healthy young and older adultsJustine M Naylor
School of Exercise and Sport Sciences, University of Sydney, NSW, Australia
Physiother Res Int 10:32-47. 2005..The present study documents the cardiovascular responses t short-term 30 degrees head-down positioning in healthy subjects. The results are a point of reference for respiratory patients with and without cardiovascular disease...
The epidemiology of heart failure in AustraliaAnthony S McLean
Department of Intensive Care Medicine, Nepean Hospital, The University of Sydney, Penrith, New South Wales, Australia
Int J Cardiol 118:370-4. 2007..Australia has one of the highest rates of cardiovascular disease in the world with heart failure representing a large proportion of this group, yet there is minimal data on the incidence or prevalence...
Cardiac biomarkers in the intensive care unitAnthony S McLean
Department of Intensive Care Medicine, Nepean Hospital, Sydney Medical School, Penrith, NSW 2750, Australia
Ann Intensive Care 2:8. 2012..This article discusses the properties and the uses of common CB, with special reference to the intensive care setting. The potential utility of "multimarkers" approach and microRNA as the future CB are also briefly discussed...
Appreciating the strengths and weaknesses of transthoracic echocardiography in hemodynamic assessmentsStephen J Huang
Department of Critical Care Medicine, Nepean Hospital, Sydney Medical School, Penrith, NSW 2750, Australia
Cardiol Res Pract 2012:894308. 2012..Various methods of hemodynamic assessments, such as cardiac output measurements, estimation of preload, and assessment of fluid responsiveness, will be discussed...
Survey of the current status of teaching intensive care medicine in Australia and New Zealand medical schoolsSarah E Whereat
Intensive Care Unit, Nepean Hospital, and Sydney Medical School, Sydney, Australia
Crit Care Med 40:430-4. 2012..The place of Intensive Care Medicine education within Medical Schools in Australia and New Zealand was investigated by survey in 2009...
International recommendations on competency in critical care ultrasound: pertinence to Australia and New ZealandAnthony S McLean
Department of Intensive Care Medicine, Nepean Hospital, University of Sydney, Sydney, NSW, Australia
Crit Care Resusc 13:56-8. 2011..Formal structures to aid the physician have been developed in Australia and New Zealand...
Predictive value of N-terminal pro-brain natriuretic peptide in sepsisBenjamin M P Tang
Crit Care Med 35:2464. 2007
