W Glenn McCluggage

Summary

Affiliation: New South Wales
Country: Australia

Publications

  1. doi request reprint Prognostic factors in prostate cancer. Key elements in structured histopathology reporting of radical prostatectomy specimens
    James G Kench
    Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, Sydney, Australia
    Pathology 43:410-9. 2011
  2. doi request reprint Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, United Kingdom
    Pathology 43:420-32. 2011
  3. doi request reprint Mesonephric adenocarcinomas of the uterine cervix and corpus: HPV-negative neoplasms that are commonly PAX8, CA125, and HMGA2 positive and that may be immunoreactive with TTF1 and hepatocyte nuclear factor 1-β
    Sarah L Kenny
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Am J Surg Pathol 36:799-807. 2012
  4. doi request reprint Papillary proliferation of the endometrium: a clinicopathologic study of 59 cases of simple and complex papillae without cytologic atypia
    Philip P C Ip
    Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China
    Am J Surg Pathol 37:167-77. 2013
  5. doi request reprint HMGA2 is a sensitive but not specific immunohistochemical marker of vulvovaginal aggressive angiomyxoma
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Am J Surg Pathol 34:1037-42. 2010
  6. doi request reprint Vulval intraepithelial neoplasia with mucinous differentiation: report of 2 cases of a hitherto undescribed phenomenon
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Am J Surg Pathol 33:945-9. 2009
  7. ncbi request reprint Papillary syncytial metaplasia associated with endometrial breakdown exhibits an immunophenotype that overlaps with uterine serous carcinoma
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 31:206-10. 2012
  8. doi request reprint Do FIGO stage IA and small (≤2 cm) IB1 cervical adenocarcinomas have a good prognosis and warrant less radical surgery?
    Moza Al-Kalbani
    Departments of Gynaecological Oncology, Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK
    Int J Gynecol Cancer 22:291-5. 2012
  9. doi request reprint Misplaced Skene's glands: glandular elements in the lower female genital tract that are variably immunoreactive with prostate markers and that encompass vaginal tubulosquamous polyp and cervical ectopic prostatic tissue
    Paul Kelly
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, UK
    Int J Gynecol Pathol 30:605-12. 2011
  10. ncbi request reprint Endometrial stromal sarcomas with extensive endometrioid glandular differentiation: report of a series with emphasis on the potential for misdiagnosis and discussion of the differential diagnosis
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland, UK
    Histopathology 54:365-73. 2009

Collaborators

Detail Information

Publications77

  1. doi request reprint Prognostic factors in prostate cancer. Key elements in structured histopathology reporting of radical prostatectomy specimens
    James G Kench
    Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, Sydney, Australia
    Pathology 43:410-9. 2011
    ..The review also discusses the International Society for Urological Pathology Consensus Conference recommendations which were published recently...
  2. doi request reprint Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, United Kingdom
    Pathology 43:420-32. 2011
    ..It is recommended that different subtypes of ovarian carcinoma are graded using different systems rather than employing a universal grading system...
  3. doi request reprint Mesonephric adenocarcinomas of the uterine cervix and corpus: HPV-negative neoplasms that are commonly PAX8, CA125, and HMGA2 positive and that may be immunoreactive with TTF1 and hepatocyte nuclear factor 1-β
    Sarah L Kenny
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Am J Surg Pathol 36:799-807. 2012
    ..As PAX8, CA125, HMGA2, and hepatocyte nuclear factor 1-β are commonly positive in a variety of Mullerian adenocarcinomas arising in the female genital tract, this may result in diagnostic confusion. All cases were WT1 negative...
  4. doi request reprint Papillary proliferation of the endometrium: a clinicopathologic study of 59 cases of simple and complex papillae without cytologic atypia
    Philip P C Ip
    Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China
    Am J Surg Pathol 37:167-77. 2013
    ..As the distinction between simple and complex PPE may be difficult in small endometrial aspirational samples, consideration for curettage should be given to ascertain whether the lesion has been completely removed...
  5. doi request reprint HMGA2 is a sensitive but not specific immunohistochemical marker of vulvovaginal aggressive angiomyxoma
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Am J Surg Pathol 34:1037-42. 2010
    ..As well as being of value in primary diagnosis, HMGA2 is useful in evaluating margins and in reexcision specimens of aggressive angiomyxoma in identifying foci of residual or recurrent tumor...
  6. doi request reprint Vulval intraepithelial neoplasia with mucinous differentiation: report of 2 cases of a hitherto undescribed phenomenon
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Am J Surg Pathol 33:945-9. 2009
    ..The mucinous cells are likely to be metaplastic and a result of aberrant differentiation in a premalignant squamous lesion...
  7. ncbi request reprint Papillary syncytial metaplasia associated with endometrial breakdown exhibits an immunophenotype that overlaps with uterine serous carcinoma
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 31:206-10. 2012
    ..HMGA2 is negative, and there is a low MIB1 proliferation index. In cases of PSM, which are morphologically problematic, the immunophenotype may further heighten the suspicion of serous malignancy and potentially result in a misdiagnosis...
  8. doi request reprint Do FIGO stage IA and small (≤2 cm) IB1 cervical adenocarcinomas have a good prognosis and warrant less radical surgery?
    Moza Al-Kalbani
    Departments of Gynaecological Oncology, Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK
    Int J Gynecol Cancer 22:291-5. 2012
    ..We wished to determine the risk of parametrial involvement and metastatic disease and the outcome in International Federation of Gynecology and Obstetrics (FIGO) stage IA and small (≤2 cm) stage IB1 cervical adenocarcinomas...
  9. doi request reprint Misplaced Skene's glands: glandular elements in the lower female genital tract that are variably immunoreactive with prostate markers and that encompass vaginal tubulosquamous polyp and cervical ectopic prostatic tissue
    Paul Kelly
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, UK
    Int J Gynecol Pathol 30:605-12. 2011
    ..Six cases were negative with both markers. We propose that these benign lesions in the cervix, vagina, and vulva are derived from eutopic or misplaced Skene's glands...
  10. ncbi request reprint Endometrial stromal sarcomas with extensive endometrioid glandular differentiation: report of a series with emphasis on the potential for misdiagnosis and discussion of the differential diagnosis
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland, UK
    Histopathology 54:365-73. 2009
    ..To describe a series of endometrial stromal sarcomas with large numbers of endometrioid-type glands...
  11. doi request reprint Myxoid change of the myometrium and cervical stroma: description of a hitherto unreported non-neoplastic phenomenon with discussion of myxoid uterine lesions
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 29:351-7. 2010
    ..Pathologists should be aware of this unusual pseudoneoplastic phenomenon to avoid a misdiagnosis of a neoplastic lesion...
  12. ncbi request reprint Tubulo-squamous polyp: a report of ten cases of a distinctive hitherto uncharacterized vaginal polyp
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Am J Surg Pathol 31:1013-9. 2007
    ....
  13. doi request reprint HMGA2 is commonly expressed in uterine serous carcinomas and is a useful adjunct to diagnosis
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Histopathology 60:547-53. 2012
    ....
  14. doi request reprint Myoepithelial neoplasms involving the vulva and vagina: report of 4 cases
    Meenakshi Meenakshi
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Hum Pathol 40:1747-53. 2009
    ..In reporting these cases, we discuss the criteria for diagnosis and the differential diagnosis...
  15. ncbi request reprint Primary malignant melanoma of the ovary: a report of 9 definite or probable cases with emphasis on their morphologic diversity and mimicry of other primary and secondary ovarian neoplasms
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 25:321-9. 2006
    ..This is an area where electron microscopy can still also contribute useful information...
  16. doi request reprint p16 Immunoreactivity in unusual types of cervical adenocarcinoma does not reflect human papillomavirus infection
    Oisin Houghton
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Histopathology 57:342-50. 2010
    ..The relationship between HPV and p16 immunoreactivity in these neoplasms was also investigated, as it is generally assumed that in cervical neoplasms diffuse p16 expression is predictive of the presence of high-risk HPV...
  17. doi request reprint An immunohistochemical study of cervical neuroendocrine carcinomas: Neoplasms that are commonly TTF1 positive and which may express CK20 and P63
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Am J Surg Pathol 34:525-32. 2010
    ..However, the absence of staining with CM2B4 argues against a true Merkel cell tumor. CD99 staining in a cervical neuroendocrine carcinoma should not result in misdiagnosis as a neoplasm in the Ewing family of tumors...
  18. doi request reprint Pseudoinvasion of benign squamous epithelium following cervical biopsy: a pseudoneoplastic phenomenon mimicking invasive squamous carcinoma
    David P Boyle
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    J Clin Pathol 64:1093-6. 2011
    ....
  19. doi request reprint Reactive fibroblastic and myofibroblastic proliferation of the vulva (Cyclist's Nodule): A hitherto poorly described vulval lesion occurring in cyclists
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Northern Ireland
    Am J Surg Pathol 35:110-4. 2011
    ..We term this lesion as reactive fibroblastic and myofibroblastic proliferation of the vulva or "cyclist's nodule."..
  20. doi request reprint Borderline ovarian mucinous neoplasm recurring as small cell carcinoma of hypercalcemic type: evidence for an epithelial histogenesis and relationship with ovarian mucinous tumors for this enigmatic neoplasm
    Sorsiah Mansor
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 30:380-5. 2011
    ..This was excluded by molecular studies that showed no evidence of EWS/FLI-1 or EWS/ERG translocation...
  21. doi request reprint Significant variation in the assessment of cervical involvement in endometrial carcinoma: an interobserver variation study
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Northern Ireland
    Am J Surg Pathol 35:289-94. 2011
    ..There is a need for specialist pathology groups dealing with gynecologic cancers to develop and disseminate recommendations regarding the assessment of cervical involvement in endometrial carcinoma...
  22. ncbi request reprint Paraganglioma of the ovary: report of three cases of a rare ovarian neoplasm, including two exhibiting inhibin positivity
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Grosvenor Road, Belfast, Northern Ireland
    Am J Surg Pathol 30:600-5. 2006
    ..Possible theories of histogenesis of primary ovarian paraganglioma include an origin from extra-adrenal paraganglia in the region of the ovary or unidirectional differentiation within a teratoma...
  23. doi request reprint Ovarian serous cystadenofibroma with signet ring-stromal cells: report of 2 cases
    Rajeev Shah
    Department of Pathology, Royal Group of Hospitals Trust, Grosvenor Road, Belfast, Northern Ireland
    Int J Gynecol Pathol 29:411-4. 2010
    ..In reporting these cases, we review ovarian stromal neoplasms and other lesions with signet ring cells...
  24. doi request reprint Metastatic carcinomas in the cervix mimicking primary cervical adenocarcinoma and adenocarcinoma in situ: report of a series of cases
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Am J Surg Pathol 34:735-41. 2010
    ..It is important for the pathologist to be aware of the possibility of cervical mucosal metastasis to avoid an erroneous diagnosis of a primary cervical adenocarcinoma or adenocarcinoma in situ...
  25. ncbi request reprint Ovarian sertoli-leydig cell tumors with pseudoendometrioid tubules (pseudoendometrioid sertoli-leydig cell tumors)
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Am J Surg Pathol 31:592-7. 2007
    ..The presence of more typical Sertoli cell elements and Leydig cells, an absence of squamous elements, endometriosis or associated adenofibroma, and the characteristic immunophenotype assist in diagnosis...
  26. ncbi request reprint Primary intestinal-type glandular lesions of the vagina: clinical, pathologic, and immunohistochemical features of 14 cases ranging from benign polyp to adenoma to adenocarcinoma
    Paul N Staats
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland Department of Pathology, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada
    Am J Surg Pathol 38:593-603. 2014
    ..The pertinent literature is reviewed, and the potential origin and differential diagnosis of these lesions are discussed. ..
  27. ncbi request reprint Ectodermal structures within the uterine cervix and vagina: report of a series of cases
    Aidan Brady
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 32:602-5. 2013
    ....
  28. doi request reprint Ovarian cellular fibromas lack FOXL2 mutations: a useful diagnostic adjunct in the distinction from diffuse adult granulosa cell tumor
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Belfast Department of Pathology, Barts Health NHS Trust, London, United Kingdom Centre for Translational and Applied Genomics Department of Pathology, University of British Columbia Department of Pathology, Vancouver General Hospital, Vancouver, BC, Canada
    Am J Surg Pathol 37:1450-5. 2013
    ..Mutation testing should be considered in problematic cases, as this will provide prognostic information for the patient. ..
  29. doi request reprint Uterine gestational choriocarcinoma developing after a long latent period in a postmenopausal woman: the value of DNA polymorphism studies
    Ciaran J O'Neill
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Int J Surg Pathol 16:226-9. 2008
    ..The report discusses the value of DNA polymorphism studies in distinguishing gestational from nongestational choriocarcinoma and from trophoblastic differentiation within a carcinoma...
  30. doi request reprint New developments in endocervical glandular lesions
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, UK
    Histopathology 62:138-60. 2013
    ..Recent developments in cervical neuroendocrine neoplasms are discussed, as these are associated not uncommonly with a premalignant or malignant endocervical glandular lesion...
  31. ncbi request reprint Florid vulval Paget disease exhibiting p16 immunoreactivity and mimicking classic VIN
    Shatrughan P Sah
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 32:221-7. 2013
    ..Florid vulval Paget disease may morphologically mimic vulval intraepithelial neoplasia, and this mimicry may be exacerbated by p16 immunoreactivity...
  32. doi request reprint DOG1 immunoreactivity in uterine leiomyosarcomas
    Shatrughan P Sah
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    J Clin Pathol 66:40-3. 2013
    ..Following the identification of DOG1 immunoreactivity in a uterine leiomyosarcoma, we wished to ascertain how prevalent DOG1 immunoreactivity was in this tumour type...
  33. doi request reprint Ten problematical issues identified by pathology review for multidisciplinary gynaecological oncology meetings
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Grosvenor Road, Belfast, BT126BA, Northern Ireland, UK
    J Clin Pathol 65:293-301. 2012
    ..This review is intended to be of practical use to the surgical pathologist reporting gynaecological cancer specimens...
  34. doi request reprint Low-grade ovarian serous neoplasms (low-grade serous carcinoma and serous borderline tumor) associated with high-grade serous carcinoma or undifferentiated carcinoma: report of a series of cases of an unusual phenomenon
    Clinton Boyd
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Am J Surg Pathol 36:368-75. 2012
    ..WT1 was negative in the 2 undifferentiated carcinomas, and PAX8 was positive in 1, suggesting that the latter marker is more useful in helping to confirm a Mullerian origin in dedifferentiated low-grade serous neoplasms...
  35. ncbi request reprint Uterine angioleiomyomas: a report of 3 cases of a distinctive benign leiomyoma variant
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, and University of Wales, Cardiff, UK
    Int J Surg Pathol 15:262-5. 2007
    ..Uterine angioleiomyoma has a close morphological resemblance to the similarly named skin tumor. We review uterine smooth-muscle and other mesenchymal neoplasms in which prominent vascular channels are a feature...
  36. ncbi request reprint Emergence of CA125 immunoreactivity in recurrent or metastatic primary ovarian mucinous neoplasms of the intestinal type
    Keith Miller
    Department of Pathology, Belfast Health and Social Care Trust, Grosvenor Road, Belfast, Northern Ireland
    Am J Surg Pathol 35:1331-6. 2011
    ....
  37. doi request reprint The expression and diagnostic utility of p63 in the female genital tract
    Oisin Houghton
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Adv Anat Pathol 16:316-21. 2009
    ..p63 is also positive in cervical transitional metaplasia, Walthard rests, vulval Paget disease secondary to an underlying urothelial malignancy, tubulosquamous polyp of the vagina, and ectopic prostatic tissue in the cervix...
  38. doi request reprint Unusual morphological features of uterine leiomyomas treated with progestogens
    Clinton Boyd
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    J Clin Pathol 64:485-9. 2011
    ....
  39. doi request reprint Cervical adenocarcinoma in situ recurring as vaginal adenocarcinoma 16 years after hysterectomy
    Daniel P Hurrell
    Department of Pathology, Royal Group of Hospitals, Belfast, Northern Ireland
    Int J Gynecol Pathol 28:296-300. 2009
    ..This is an extremely rare phenomenon with, as far as we are aware, only one previous report in the literature...
  40. doi request reprint Mullerian adenosarcoma of the female genital tract
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Adv Anat Pathol 17:122-9. 2010
    ..Ovarian adenosarcomas are much more likely to exhibit malignant behavior than their uterine counterparts, probably due to the lack of an anatomic barrier to peritoneal dissemination...
  41. pmc Ewing family of tumours involving the vulva and vagina: report of a series of four cases
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    J Clin Pathol 60:674-80. 2007
    ..In this study, four new cases of EFTs involving the vulva (three cases) or vagina (one case) are reported...
  42. doi request reprint Data set for reporting of endometrial carcinomas: recommendations from the International Collaboration on Cancer Reporting (ICCR) between United Kingdom, United States, Canada, and Australasia
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 32:45-65. 2013
    ..This review describes the process of development of the endometrial cancer data set...
  43. doi request reprint Immunohistochemistry in the distinction between primary and metastatic ovarian mucinous neoplasms
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    J Clin Pathol 65:596-600. 2012
    ..Mullerian type primary ovarian mucinous neoplasms also exist and exhibit distinct immunohistochemical differences to the more common intestinal type...
  44. doi request reprint Inverted papilloma of the cervix and vagina: report of 2 cases of a rare lesion associated with human papillomavirus 42
    Claire Hennell
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland BT 12 6BA
    Hum Pathol 43:435-9. 2012
    ..Our results suggest that these neoplasms when occurring in the lower female genital tract may be associated with low-risk human papillomavirus, perhaps specifically human papillomavirus 42...
  45. ncbi request reprint Immunohistochemistry as a diagnostic aid in the evaluation of ovarian tumors
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Semin Diagn Pathol 22:3-32. 2005
    ....
  46. ncbi request reprint CD56 is a sensitive and diagnostically useful immunohistochemical marker of ovarian sex cord-stromal tumors
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 26:322-7. 2007
    ....
  47. ncbi request reprint Oxyphilic adenomatoid tumor of the ovary: a case report with discussion of the differential diagnosis of ovarian tumors with vacuoles and related spaces
    Victoria Phillips
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 26:16-20. 2007
    ..In reporting this case, we focus on the differential diagnosis of ovarian neoplasms and tumorlike conditions with vacuoles and related spaces, a topic that embraces many diverse entities...
  48. doi request reprint The pathology of and controversial aspects of ovarian borderline tumours
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Grosvenor Road, Belfast, Northern Ireland, UK
    Curr Opin Oncol 22:462-72. 2010
    ..Ovarian borderline tumours are relatively uncommon, but not rare, neoplasms. Pathologists and oncologists often struggle with various aspects of borderline tumours which are sometimes controversial and poorly understood...
  49. doi request reprint Endometrial stromal sarcomas with true papillae and pseudopapillae
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 27:555-61. 2008
    ..The formation of papillae or pseudopapillae may result in diagnostic difficulty and confusion with other neoplasms, especially if the phenomenon is widespread...
  50. doi request reprint Uterine composite tumor composed of leiomyosarcoma and embryonal rhabdomyosarcoma with immature cartilage
    Monika Verma
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 28:338-42. 2009
    ..This is likely to represent rhabdomyosarcomatous differentiation in a leiomyomatous neoplasm or alternatively bidirectional differentiation from an uncommitted mesenchymal stem cell...
  51. doi request reprint Which staging system to use for gynaecological cancers: a survey with recommendations for practice in the UK
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, UK
    J Clin Pathol 63:768-70. 2010
    ..The authors wished to ascertain which staging system is most commonly used in dealing with gynaecological cancers in the UK...
  52. ncbi request reprint A Strategy for defining biologically relevant levels of p53 protein expression in clinical samples with reference to endometrial neoplasia
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 24:307-12. 2005
    ..Thirdly, standardization between laboratories is necessary if clinical utility is to be attached to markers including p53. We propose a strategy for determining the optimal p53 antibody concentration...
  53. doi request reprint Epidermal growth factor receptor (EGFR), HER2 and insulin-like growth factor-1 receptor (IGF-1R) status in ovarian adult granulosa cell tumours
    Patricia A Higgins
    Northern Ireland Molecular Pathology Laboratory, Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast Health and Social Care Trust, Belfast, UK Department of Pathology, Belfast Health and Social Care Trust, Belfast, UK
    Histopathology 64:633-8. 2014
    ....
  54. doi request reprint Peritoneal bile granulomas identified at Cesarean section and mimicking disseminated malignancy
    Gerard McVeigh
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Int J Surg Pathol 20:89-91. 2012
    ..This may become increasingly common in the future since bile leakage is more likely to occur with laparoscopic than open cholecystectomy...
  55. doi request reprint Primary vaginal mucinous adenocarcinoma of gastric type arising in adenosis: a report of 2 cases, 1 associated with uterus didelphys
    Karen L Talia
    Department of Pathology, Box Hill Hospital, Eastern Health, Melbourne, Victoria, Australia
    Int J Gynecol Pathol 31:184-191. 2012
    ....
  56. ncbi request reprint Immunohistochemical and functional biomarkers of value in female genital tract lesions
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 25:101-20. 2006
    ..It is stressed that when immunohistochemistry is used diagnostically, panels of markers provide better information than reliance on a single antibody...
  57. ncbi request reprint Immunohistochemistry as a diagnostic aid in cervical pathology
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospital Trust, Belfast, Northern Ireland
    Pathology 39:97-111. 2007
    ....
  58. doi request reprint Vascular involvement in adenomyosis: report of a large series of a common phenomenon with observations on the pathogenesis of adenomyosis
    Meenakshi Meenakshi
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland, UK
    Int J Gynecol Pathol 29:117-21. 2010
    ..The pattern of vascular involvement raises the possibility that adenomyosis develops from cells intimately associated with myometrial blood vessels, perhaps multipotential perivascular cells...
  59. ncbi request reprint Ovarian serous cystadenofibroma with stromal sex cord elements: report of a unique case
    Katrina Dillon
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 25:336-9. 2006
    ..The endometrium exhibited simple hyperplasia, perhaps secondary to estrogenic activity of the sex cord elements. We discuss the significance of CD56 positivity of the sex cord elements...
  60. ncbi request reprint Primary ovarian mucinous tumors with signet ring cells: report of 3 cases with discussion of so-called primary Krukenberg tumor
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Am J Surg Pathol 32:1373-9. 2008
    ..The tumors should be classified according to the underlying background neoplasm with a notation concerning the signet ring cell component...
  61. ncbi request reprint Postirradiation primary vaginal angiosarcoma with widespread intra-abdominal metastasis
    Aidan Brady
    Department of Pathology, Gynaecological Oncology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 30:514-7. 2011
    ..All of the earlier reported cases have been localized to the pelvis without metastatic disease...
  62. ncbi request reprint Atypical reactive proliferation of endocervix: a common lesion associated with endometrial carcinoma and likely related to prior endometrial sampling
    Michael Scott
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland, UK
    Mod Pathol 19:470-4. 2006
    ..The vimentin-negative immunophenotype may be of value in cases where the uterine carcinoma is endometrioid in type as these neoplasms are generally vimentin positive...
  63. doi request reprint Low-grade epithelial-myoepithelial carcinoma of bartholin gland: report of 2 cases of a distinctive neoplasm arising in the vulvovaginal region
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, UK
    Int J Gynecol Pathol 28:286-91. 2009
    ..We propose the term low-grade epithelial-myoepithelial carcinoma of Bartholin gland...
  64. doi request reprint Symplastic atypia in neoplastic and non-neoplastic endometrial stroma: report of 3 cases with a review of atypical symplastic cells within the female genital tract
    Rajeev Shah
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 28:334-7. 2009
    ..In reporting these cases, we review normal tissues and pathologic lesions in the female genital tract with atypical symplastic nuclei...
  65. doi request reprint Abdominal wall endometriosis associated with ventriculoperitoneal and lumboperitoneal shunts: a report of 2 cases of an extremely rare phenomenon
    Estelle G Healy
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Int J Surg Pathol 20:301-4. 2012
    ..However, it should be considered in the differential diagnosis when a mass develops at a shunt site in a woman of reproductive age...
  66. doi request reprint A detailed immunohistochemical analysis of 2 cases of papillary cystadenoma of the broad ligament: an extremely rare neoplasm characteristic of patients with von hippel-lindau disease
    Aidan Brady
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 31:133-40. 2012
    ..This is the second reported example of papillary cystadenoma in a woman not known to have VHL disease and the first in which investigations have excluded this disease...
  67. ncbi request reprint An immunohistochemical comparison between low-grade and high-grade ovarian serous carcinomas: significantly higher expression of p53, MIB1, BCL2, HER-2/neu, and C-KIT in high-grade neoplasms
    Ciaran J O'Neill
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Am J Surg Pathol 29:1034-41. 2005
    ..In particular, the differences in p53 immunoreactivity are in keeping with the observation that p53 gene mutation is more common in high-grade than low-grade OSC...
  68. ncbi request reprint Ectopic prostatic tissue in the uterine cervix and vagina: report of a series with a detailed immunohistochemical analysis
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, UK
    Am J Surg Pathol 30:209-15. 2006
    ..Possible theories of histogenesis include a developmental anomaly, metaplasia of preexisting endocervical glands, and derivation from mesonephric remnants...
  69. pmc Cervical embryonal rhabdomyosarcoma and ovarian Sertoli-Leydig cell tumour: a more than coincidental association of two rare neoplasms?
    Gareth E McClean
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    J Clin Pathol 60:326-8. 2007
    ..These were interpreted as foci of bizarre nuclei within the Sertoli-Leydig cell tumour...
  70. ncbi request reprint A critical appraisal of the value of immunohistochemistry in diagnosis of uterine neoplasms
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Adv Anat Pathol 11:162-71. 2004
    ....
  71. doi request reprint Massive vulval edema secondary to obesity and immobilization: a potential mimic of aggressive angiomyxoma
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland
    Int J Gynecol Pathol 27:447-52. 2008
    ..Clinicians and pathologists should be aware of the existence of this lesion, which is likely due to lymphatic obstruction and lymphedema secondary to immobilization and obesity...
  72. ncbi request reprint Miscellaneous disorders involving the endometrium
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Semin Diagn Pathol 27:287-310. 2010
    ..Various issues relating to endometrial polyps are also covered, as are metastatic neoplasms involving the endometrium...
  73. doi request reprint Serum CA19.9 levels are commonly elevated in primary ovarian mucinous tumours but cannot be used to predict the histological subtype
    Paul J Kelly
    Department of Pathology, Royal Group of Hospitals, Belfast, UK
    J Clin Pathol 63:169-73. 2010
    ..The aim of this study was to correlate the serum CA19.9 level with the histological features in a large series of primary ovarian mucinous neoplasms...
  74. doi request reprint Endometrial adenocarcinoma with signet ring cells: report of two cases of an extremely rare phenomenon
    Clinton Boyd
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 29:579-82. 2010
    ..One of the neoplasms arose within adenomyosis. In reporting these cases, we illustrate that the presence of signet ring cells does not preclude a primary endometrial adenocarcinoma.We discuss signet ring cells in the endometrium...
  75. doi request reprint Cervical adenocarcinoma resembling breast lobular carcinoma: a hitherto Undescribed Variant of Primary Cervical Adenocarcinoma
    Sorsiah Mansor
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Int J Gynecol Pathol 29:594-9. 2010
    ..In reporting these cases, we highlight an unusual morphologic variant of cervical adenocarcinoma closely resembling breast lobular carcinoma and which may have an aggressive behavior...
  76. doi request reprint Composite cervical adenocarcinoma composed of adenoma malignum and gastric type adenocarcinoma (dedifferentiated adenoma malignum) in a patient with Peutz Jeghers syndrome
    W Glenn McCluggage
    Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK
    J Clin Pathol 63:935-41. 2010
    ..This raises the possibility of a relationship between these two uncommon types of cervical adenocarcinoma, both of which are thought to exhibit gastric differentiation...
  77. ncbi request reprint A review and update of morphologically bland vulvovaginal mesenchymal lesions
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Grosvenor Road, Belfast, BT12 6BL, Northern Ireland
    Int J Gynecol Pathol 24:26-38. 2005
    ....