Jo Dee L Lattimore
Affiliation: New South Wales
- Obstructive sleep apnea and cardiovascular diseaseJo Dee L Lattimore
Department of Cardiology, Royal Prince Alfred Hospital, NSW, Sydney, Australia
J Am Coll Cardiol 41:1429-37. 2003..Despite the availability of effective therapy, OSA remains an underdiagnosed and undertreated condition. A lack of physician awareness is one of the primary reasons for this deficit in diagnosis and treatment...
- Repetitive hypoxia increases lipid loading in human macrophages-a potentially atherogenic effectJo Dee L Lattimore
Department of Cardiology, Royal Prince Alfred Hospital, Missenden Road, Camperdown, Sydney, NSW 2050, Australia
Atherosclerosis 179:255-9. 2005..1). Repetitive hypoxia, at levels relevant to tissues such as the arterial wall, enhances lipid uptake into human macrophages. This may contribute to accelerated atherosclerosis in OSA patients...
- Treatment of obstructive sleep apnoea leads to improved microvascular endothelial function in the systemic circulationJ L Lattimore
Department of Cardiology, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2050, and Department of Medicine, University of Sydney, Australia
Thorax 61:491-5. 2006..Microvascular arterial endothelial and smooth muscle function was assessed in subjects with OSA before and after treatment with continuous positive airways pressure (CPAP)...
- Treatment of obstructive sleep apnoea leads to enhanced pulmonary vascular nitric oxide releaseJo Dee L Lattimore
Department of Cardiology, Royal Prince Alfred Hospital Sydney, NSW, Australia
Int J Cardiol 126:229-33. 2008..Obstructive sleep apnoea (OSA) is associated with pulmonary hypertension, however neither the pathogenesis of pulmonary vascular disease nor the effect of successful treatment of OSA on pulmonary vascular physiology has been characterised...