Research Topics
| David GoldsteinSummaryAffiliation: New South Wales Country: Australia Publications
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Detail Information
Publications
The GOFURTGO Study: AGITG phase II study of fixed dose rate gemcitabine-oxaliplatin integrated with concomitant 5FU and 3-D conformal radiotherapy for the treatment of localised pancreatic cancerD Goldstein
Department of Medical Oncology, Prince of Wales Hospital, High Street, Randwick, New South Wales 2031, Australia
Br J Cancer 106:61-9. 2012....- Gemcitabine with a specific conformal 3D 5FU radiochemotherapy technique is safe and effective in the definitive management of locally advanced pancreatic cancerD Goldstein
Department of Medical Oncology, Prince of Wales Hospital, Barker Street, Randwick, New South Wales 2031, Australia
Br J Cancer 97:464-71. 2007..This approach to treatment of locally advanced pancreatic cancer is safe and promising, with good local control for a substantial proportion of patients, and merits testing in a randomised trial... 
Oxaliplatin-induced neurotoxicity: changes in axonal excitability precede development of neuropathySusanna B Park
Prince of Wales Medical Research Institute, Barker Street, Randwick, Sydney, NSW 2031, Australia
Brain 132:2712-23. 2009..05) than those left with mild or moderate neurotoxicity, suggesting that assessment of sensory excitability parameters may provide a sensitive biomarker of severity for oxaliplatin-induced neurotoxicity...- Utilizing natural activity to dissect the pathophysiology of acute oxaliplatin-induced neuropathySusanna B Park
Prince of Wales Clinical School, Barker Street, Randwick, Sydney, NSW 2063, Australia
Exp Neurol 227:120-7. 2011..Findings from the present series suggest that oxaliplatin affects nerve excitability through voltage-dependent mechanisms, with specific effects mediated through axonal Na(+) channel inactivation... - Acute abnormalities of sensory nerve function associated with oxaliplatin-induced neurotoxicitySusanna B Park
Prince of Wales Medical Research Institute, Barker St, Randwick, Sydney, New South Wales 2031
J Clin Oncol 27:1243-9. 2009..Because the mechanism of oxaliplatin-induced neurotoxicity remains unclear, the present study investigated the potential of axonal excitability techniques in identifying pathophysiologic mechanisms and early markers of nerve dysfunction... 
The experience of cancer-related fatigue and chronic fatigue syndrome: a qualitative and comparative studyBarbara Bennett
Department of Medical Oncology, Prince of Wales Hospital, Sydney, Australia
J Pain Symptom Manage 34:126-35. 2007..Qualitatively, CRF appears closely related to CFS. These findings raise the emergent hypothesis of a conserved neurobehavioral symptom complex, which results from diverse triggering insults...- Impact of gemcitabine chemotherapy and 3-dimensional conformal radiation therapy/5-fluorouracil on quality of life of patients managed for pancreatic cancerMichala Short
Discipline of Medical Radiation Sciences, University of Sydney, and Department of Medical Oncology, Prince of Wales Hospital, Sydney, New South Wales, Australia
Int J Radiat Oncol Biol Phys 85:157-62. 2013..To report quality of life (QOL) results for patients receiving chemoradiation therapy for pancreatic cancer... - Cancer-related fatigue in women with breast cancer: outcomes of a 5-year prospective cohort studyDavid Goldstein
Prince of Wales Hospital, Randwick, Australia
J Clin Oncol 30:1805-12. 2012..Hence, relationships to cancer, surgery, and adjuvant therapy are unclear... - Modification of leucovorin dose within a simplified FOLFOX regimen improves tolerability without compromising efficacyStephen Clarke
Department of Medical Oncology, Royal Prince Alfred Hospital Sydney Cancer Centre, Sydney, Australia
Clin Colorectal Cancer 6:578-82. 2007..This analysis assesses the efficacy and safety of a modified FOLFOX (oxaliplatin/leucovorin [LV]/5-fluorouracil [5-FU]) regimen given with a low dose of LV... - If I am in the mood, I enjoy it: an exploration of cancer-related fatigue and sexual functioning in women with breast cancerKate Webber
Department of Medical Oncology, Prince of Wales Hospital, High Street, Randwick, New South Wales 2031, Australia
Oncologist 16:1333-44. 2011..The current paper describes sexual functioning (SF) and its relationship to CRF, mood disorder, and quality of life (QOL) over the first year after completion of adjuvant therapy... - Fatigue states after cancer treatment occur both in association with, and independent of, mood disorder: a longitudinal studyDavid Goldstein
Department of Medical Oncology, Prince of Wales Hospital, Sydney, Australia
BMC Cancer 6:240. 2006..We sought to examine the longitudinal relationships between fatigue and mood disorder in women treated with adjuvant therapy for early stage breast cancer... - Oxaliplatin and axonal Na+ channel function in vivoArun V Krishnan
Institute of Neurological Sciences, Prince of Wales Hospital, Sydney, New South Wales, Australia
Clin Cancer Res 12:4481-4. 2006..Clinical nerve excitability techniques may prove beneficial in monitoring for early signs of neurotoxicity and in the assessment of future prophylactic therapies... - A serious complication of selected internal radiation therapy: case report and literature reviewKatrin M Sjoquist
Department of Medical Oncology, Prince of Wales Hospital, High Street, Randwick, NSW Australia
Oncologist 15:830-5. 2010..The characteristic endoscopic, radiologic, and histopathologic findings are illustrated and recommendations are reviewed with regard to the current literature... - Fixed-dose-rate gemcitabine combined with cisplatin in patients with inoperable biliary tract carcinomasDavid Goldstein
Department of Medical Oncology, Prince of Wales Hospital, Randwick, NSW, Australia
Cancer Chemother Pharmacol 67:519-25. 2011..Biliary tract cancers (BTC) have a poor prognosis, and there is no consensus on the best chemotherapy regimen. This study determined the response rate for fixed-dose-rate (FDR) gemcitabine combined with cisplatin... - Reaching further with online education? The development of an effective online program in palliative oncologyBogda Koczwara
Department of Medical Oncology, Flinders Medical Centre, Bedford Park, SA 5042, Australia
J Cancer Educ 25:317-23. 2010..Sixty-five (75%) respondents planned to review or change their practice as a result. The online program is effective in meeting learning needs of Australian health providers, reaching high numbers with high acceptability... - Clinical supervision and education via videoconference: a feasibility projectKristina Xavier
Department of Medical Oncology, Prince of Wales Hospital, Randwick, NSW, Australia
J Telemed Telecare 13:206-9. 2007..3 out of 10). With regard to telephone supervision, most (80%) were very or extremely satisfied. The feedback indicated that remote supervision was well received and that participants were keen to continue their involvement... - Primary pancreatic lymphoma--pancreatic tumours that are potentially curable without resection, a retrospective review of four casesPeter S Grimison
Institute of Oncology, Prince of Wales Hospital, Sydney, Australia
BMC Cancer 6:117. 2006..Symptoms, imaging and tumour markers can mimic pancreatic adenocarcinoma, but they are much more amenable to treatment. Treatment for PPL remains controversial, particularly the role of surgical resection...