Zhi Cheng Xiao


Affiliation: Monash University
Country: Australia


  1. Qiu C, Liu Z, Zhang F, Zhang L, Li F, Liu S, et al. Post-stroke gastrodin treatment ameliorates ischemic injury and increases neurogenesis and restores the Wnt/β-Catenin signaling in focal cerebral ischemia in mice. Brain Res. 2019;1712:7-15 pubmed publisher
    ..Our findings suggest that gastrodin treatment following ischemic injury can induce neuroprotection, promote neurogenesis and restored the Wnt /β-Catenin signaling pathway. ..
  2. Qiu C, Liu Z, Hou K, Liu S, Hu Y, Zhang L, et al. Wip1 knockout inhibits neurogenesis by affecting the Wnt/β-catenin signaling pathway in focal cerebral ischemia in mice. Exp Neurol. 2018;309:44-53 pubmed publisher
    ..These findings indicate that WIP1 is essential for neurogenesis after brain injury by activating the Wnt/β-Catenin signaling pathway. ..
  3. Wang W, Lu L, Bao T, Zhang H, Yuan J, Miao W, et al. Scutellarin Alleviates Behavioral Deficits in a Mouse Model of Multiple Sclerosis, Possibly Through Protecting Neural Stem Cells. J Mol Neurosci. 2016;58:210-20 pubmed publisher
    ..In summary, scutellarin could alleviate motor deficits in a mouse model for MS, possibly by inhibiting NSC apoptosis and promoting differentiation of NSCs to myelin-producing oligodendrocytes. ..
  4. Liu C, Tan F, Xiao Z, Dawe G. Amyloid precursor protein enhances Nav1.6 sodium channel cell surface expression. J Biol Chem. 2015;290:12048-57 pubmed publisher
    ..Phosphorylation of APP695 at Thr-668 enhanced its interaction with Nav1.6. Therefore, we show that APP enhances Nav1.6 sodium channel cell surface expression through a Go-coupled JNK pathway. ..
  5. Liu C, Zhang C, Zhou Y, Wong W, Lee L, Ong W, et al. APP upregulation contributes to retinal ganglion cell degeneration via JNK3. Cell Death Differ. 2018;25:661-676 pubmed publisher
    ..This pathway may be a novel target for neuronal protection in optic neuropathies and other forms of neurotrauma. ..