E W Wolvetang
Affiliation: Monash University
- The chromosome 21 transcription factor ETS2 transactivates the beta-APP promoter: implications for Down syndromeE W Wolvetang
Centre for Functional Genomics and Human Disease, Monash Institute of Reproduction and Development, Monash University, Monash Medical Center, 246 Clayton Road, 3168, Clayton, Australia
Biochim Biophys Acta 1628:105-10. 2003..We conclude that ETS2 is a transcriptional regulator of beta-APP and that overexpression of ETS2 in DS may play a role in the pathogenesis of the brain abnormalities in DS and possibly AD...
- Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosisE J Wolvetang
Monash Institute of Reproduction and Development, Monash University, Monash Medical Center, 246 Clayton Road, 3168 Clayton, Australia
Neurobiol Dis 14:349-56. 2003..Our data therefore suggest that overexpression of ETS2 may contribute to the increased rate of apoptosis of neurons in Down syndrome...
- Gap junction mediated transport of shRNA between human embryonic stem cellsErnst J Wolvetang
The Australian Stem Cell Centre and Department of Anatomy and Cell Biology, Monash University, Building 75 STRIP, Wellington Road, Clayton, VIC 3800, Australia
Biochem Biophys Res Commun 363:610-5. 2007..This novel intercellular gene expression regulatory mechanism may offer new approaches to manipulation of hESC...
- Essential roles of sphingosine-1-phosphate and platelet-derived growth factor in the maintenance of human embryonic stem cellsAlice Pebay
Monash Institute of Medical Research, Laboratory of Embryonic Stem Cell Biology, Australian Stem Cell Centre, STRIP Monash University, Clayton VIC 3800, Australia
Stem Cells 23:1541-8. 2005..This study is the first demonstration of a role for lysophospholipid receptor signaling in the maintenance of stem cell pluri-potentiality...