David R Williams

Summary

Affiliation: Monash University
Country: Australia

Publications

  1. ncbi request reprint Progressive supranuclear palsy: clinicopathological concepts and diagnostic challenges
    David R Williams
    Faculty of Medicine Neurosciences, Monash University, Melbourne, Australia
    Lancet Neurol 8:270-9. 2009
  2. ncbi request reprint Influence of single nucleotide polymorphisms in COMT, MAO-A and BDNF genes on dyskinesias and levodopa use in Parkinson's disease
    Perdita Cheshire
    Department of Medicine Neuroscience, Monash University Alfred Hospital, Melbourne, Vic, Australia
    Neurodegener Dis 13:24-8. 2014
  3. doi request reprint What features improve the accuracy of the clinical diagnosis of progressive supranuclear palsy-parkinsonism (PSP-P)?
    David R Williams
    Van Cleef Roet Centre for Nervous Diseases, Monash University, Melbourne, Victoria, Australia
    Mov Disord 25:357-62. 2010
  4. doi request reprint Biological fluid biomarkers in neurodegenerative parkinsonism
    Michael Eller
    Department of Neurosciences, Alfred Hospital, Melbourne, Victoria, Australia
    Nat Rev Neurol 5:561-70. 2009
  5. doi request reprint Characterising the uncommon corticobasal syndrome presentation of sporadic Creutzfeldt-Jakob disease
    Will Lee
    Department of Neuroscience, The Alfred Hospital, Commercial Road, Melbourne, Victoria 3004, Australia
    Parkinsonism Relat Disord 19:81-5. 2013
  6. doi request reprint J. Clifford Richardson and 50 years of progressive supranuclear palsy
    David R Williams
    Faculty of Medicine, Monash University, Alfred Hospital Campus, Melbourne, Australia
    Neurology 70:566-73. 2008
  7. doi request reprint α-Synuclein in Parkinson disease and other neurodegenerative disorders
    Michael Eller
    Department of Neurosciences, Alfred Hospital, Melbourne, Australia
    Clin Chem Lab Med 49:403-8. 2011
  8. ncbi request reprint Clinical, laboratory and electrophysiological features of Morvan's fibrillary chorea
    Will Lee
    Department of Neuroscience, Alfred Hospital, Commercial Road, Melbourne, Victoria 3004, Australia
    J Clin Neurosci 20:1246-9. 2013
  9. doi request reprint Cognitive testing in the diagnosis of parkinsonian disorders: a critical appraisal of the literature
    Will Lee
    Department of Neuroscience, The Alfred Hospital, Melbourne, Victoria, Australia
    Mov Disord 27:1243-54. 2012
  10. doi request reprint Serotonergic involvement in levodopa-induced dyskinesias in Parkinson's disease
    Perdita A Cheshire
    Van Cleef Roet Centre for Nervous Diseases, 4th Floor, Monash University, Alfred Hospital, 89 Commercial Road, Melbourne, Victoria 3004, Australia
    J Clin Neurosci 19:343-8. 2012

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Progressive supranuclear palsy: clinicopathological concepts and diagnostic challenges
    David R Williams
    Faculty of Medicine Neurosciences, Monash University, Melbourne, Australia
    Lancet Neurol 8:270-9. 2009
    ..In this way, the development of the clinical features can be informative in assigning less common nosological categories that give clues to the underlying pathology and an understanding of the expected clinical course...
  2. ncbi request reprint Influence of single nucleotide polymorphisms in COMT, MAO-A and BDNF genes on dyskinesias and levodopa use in Parkinson's disease
    Perdita Cheshire
    Department of Medicine Neuroscience, Monash University Alfred Hospital, Melbourne, Vic, Australia
    Neurodegener Dis 13:24-8. 2014
    ..Clinical heterogeneity in the development of levodopa-induced dyskinesias (LID) suggests endogenous factors play a significant role in determining their overall prevalence...
  3. doi request reprint What features improve the accuracy of the clinical diagnosis of progressive supranuclear palsy-parkinsonism (PSP-P)?
    David R Williams
    Van Cleef Roet Centre for Nervous Diseases, Monash University, Melbourne, Victoria, Australia
    Mov Disord 25:357-62. 2010
    ..PSP-P shares many clinical features with PD and DLB, MSA and VP, but visual hallucinations, drug induced dyskinesias and autonomic dysfunction are very uncommon and may be helpful exclusion criteria...
  4. doi request reprint Biological fluid biomarkers in neurodegenerative parkinsonism
    Michael Eller
    Department of Neurosciences, Alfred Hospital, Melbourne, Victoria, Australia
    Nat Rev Neurol 5:561-70. 2009
    ..Despite such difficulties, improved technology, in conjunction with advances in nosology and pathology, means that biomarkers are poised to enter routine clinical practice to aid the differentiation of parkinsonian disorders...
  5. doi request reprint Characterising the uncommon corticobasal syndrome presentation of sporadic Creutzfeldt-Jakob disease
    Will Lee
    Department of Neuroscience, The Alfred Hospital, Commercial Road, Melbourne, Victoria 3004, Australia
    Parkinsonism Relat Disord 19:81-5. 2013
    ..It may occur in other neurodegenerative disorders including sporadic Creutzfeldt-Jakob disease (sCJD). Current CBD diagnostic criteria outline features of CBS but fail to distinguish CBD from other causative pathologies...
  6. doi request reprint J. Clifford Richardson and 50 years of progressive supranuclear palsy
    David R Williams
    Faculty of Medicine, Monash University, Alfred Hospital Campus, Melbourne, Australia
    Neurology 70:566-73. 2008
    ..To trace the historical events leading to Richardson's clinical description of progressive supranuclear palsy (PSP) in the context of subsequent observations of its clinical heterogeneity and pathologic overlap with other tauopathies...
  7. doi request reprint α-Synuclein in Parkinson disease and other neurodegenerative disorders
    Michael Eller
    Department of Neurosciences, Alfred Hospital, Melbourne, Australia
    Clin Chem Lab Med 49:403-8. 2011
    ..Future studies using standardized techniques and larger patient numbers are awaited to realise the full potential of αS as a more definitive diagnostic biomarker...
  8. ncbi request reprint Clinical, laboratory and electrophysiological features of Morvan's fibrillary chorea
    Will Lee
    Department of Neuroscience, Alfred Hospital, Commercial Road, Melbourne, Victoria 3004, Australia
    J Clin Neurosci 20:1246-9. 2013
    ..Early initiation of immunotherapies and malignancy screening are important to prevent adverse outcomes in a condition that generally responds favourably to treatment. ..
  9. doi request reprint Cognitive testing in the diagnosis of parkinsonian disorders: a critical appraisal of the literature
    Will Lee
    Department of Neuroscience, The Alfred Hospital, Melbourne, Victoria, Australia
    Mov Disord 27:1243-54. 2012
    ..Even these features must be interpreted in conjunction with other clinical characteristics to be helpful diagnostically. © 2012 Movement Disorder Society...
  10. doi request reprint Serotonergic involvement in levodopa-induced dyskinesias in Parkinson's disease
    Perdita A Cheshire
    Van Cleef Roet Centre for Nervous Diseases, 4th Floor, Monash University, Alfred Hospital, 89 Commercial Road, Melbourne, Victoria 3004, Australia
    J Clin Neurosci 19:343-8. 2012
    ....
  11. pmc Visual hallucinations in the differential diagnosis of parkinsonism
    Kelly Bertram
    Neurology Department, Alfred Hospital, Melbourne, Victoria, Australia
    J Neurol Neurosurg Psychiatry 83:448-52. 2012
    ..In this review, the published frequencies of VH in these different conditions are compared to put into context the notion of VH as a clinical clue to underlying Lewy body pathology...
  12. doi request reprint Inhibitory control during smooth pursuit in Parkinson's disease and Huntington's disease
    Tracy Henderson
    School of Psychology and Psychiatry, Clayton Campus, Monash University, Victoria, Australia
    Mov Disord 26:1893-9. 2011
    ..This suggests that ocular motility may provide a sensitive marker of clinical disease progression in Huntington's disease...
  13. ncbi request reprint My hands shake--classification and treatment of tremor
    Dharshana Sirisena
    Van Cleef Roet Centre for Nervous Diseases, Monash University, Melbourne, Victoria
    Aust Fam Physician 38:678-83. 2009
    ..Most tremors can be separated according to the state in which they occur, that is, during rest or action. Other clinical features, including frequency, amplitude and associated neurological signs, further define tremor...
  14. ncbi request reprint Pure akinesia with gait freezing: a third clinical phenotype of progressive supranuclear palsy
    David R Williams
    Faculty of Medicine Neurosciences, Monash University Alfred Hospital Campus, Melbourne, Australia
    Mov Disord 22:2235-41. 2007
    ..This relatively uncommon presentation of PSP-tau pathology has less severe tau accumulation than in the more common, "classic" PSP clinical phenotype: Richardson's disease...