- Angiotensin-converting enzyme-2: a molecular and cellular perspectiveF J Warner
School of Biochemistry and Microbiology, University of Leeds, Leeds LS2 9JT, United Kingdom
Cell Mol Life Sci 61:2704-13. 2004....
- Membrane-associated zinc peptidase families: comparing ACE and ACE2J L Guy
Proteolysis Research Group, School of Biochemistry and Microbiology, University of Leeds, Leeds, LS2 9JT, UK
Biochim Biophys Acta 1751:2-8. 2005..As the complexity of this crucial pathway is unravelled, there is a growing interest in the therapeutic potential of agents that modulate the activity of ACE2...
- Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2G Paizis
University of Melbourne, Department of Medicine, Austin Health, Heidelberg, Victoria, Australia
Gut 54:1790-6. 2005..CONCLUSIONS: ACE2 expression is significantly increased in liver injury in both humans and rat, possibly in response to increasing hepatocellular hypoxia, and may modulate RAS activity in cirrhosis...