Ana Traven

Summary

Affiliation: Monash University
Country: Australia

Publications

  1. pmc The functions of Mediator in Candida albicans support a role in shaping species-specific gene expression
    Nathalie Uwamahoro
    Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia
    PLoS Genet 8:e1002613. 2012
  2. pmc Transcriptional profiling of a yeast colony provides new insight into the heterogeneity of multicellular fungal communities
    Ana Traven
    Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia
    PLoS ONE 7:e46243. 2012
  3. pmc Mitochondrial sorting and assembly machinery subunit Sam37 in Candida albicans: insight into the roles of mitochondria in fitness, cell wall integrity, and virulence
    Yue Qu
    Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, Australia
    Eukaryot Cell 11:532-44. 2012
  4. pmc A model system for mitochondrial biogenesis reveals evolutionary rewiring of protein import and membrane assembly pathways
    Victoria L Hewitt
    Department of Biochemistry and Molecular Biology and Victorian Bioinformatics Consortium, Monash University, Melbourne, VIC 3800, Australia
    Proc Natl Acad Sci U S A 109:E3358-66. 2012
  5. doi request reprint Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2
    Michael J Dagley
    Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia
    Mol Microbiol 79:968-89. 2011
  6. pmc The mRNA decay pathway regulates the expression of the Flo11 adhesin and biofilm formation in Saccharomyces cerevisiae
    Tricia L Lo
    Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia
    Genetics 191:1387-91. 2012
  7. doi request reprint The ins and outs of the intermembrane space: diverse mechanisms and evolutionary rewiring of mitochondrial protein import routes
    Victoria L Hewitt
    Department of Biochemistry and Molecular Biology, Building 77, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne 3800, Australia Electronic address
    Biochim Biophys Acta 1840:1246-53. 2014
  8. pmc ifet-1 is a broad-scale translational repressor required for normal P granule formation in C. elegans
    Madhu S Sengupta
    Department of Biochemistry and Molecular Biology, Monash University, Victoria 3800, Australia
    J Cell Sci 126:850-9. 2013
  9. ncbi request reprint Guanylated polymethacrylates: a class of potent antimicrobial polymers with low hemolytic activity
    Katherine E S Locock
    CSIRO Materials Science and Engineering, Bayview Avenue, Clayton, Victoria 3168, Australia
    Biomacromolecules 14:4021-31. 2013
  10. pmc Identification and mechanism of action of the plant defensin NaD1 as a new member of the antifungal drug arsenal against Candida albicans
    Brigitte M E Hayes
    La Trobe Institute for Molecular Science, Melbourne, Victoria, Australia
    Antimicrob Agents Chemother 57:3667-75. 2013

Collaborators

Detail Information

Publications15

  1. pmc The functions of Mediator in Candida albicans support a role in shaping species-specific gene expression
    Nathalie Uwamahoro
    Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia
    PLoS Genet 8:e1002613. 2012
    ..cerevisiae and are activators of the ALS genes in C. albicans. This suggests that Mediator subunits regulate adhesion in a distinct manner between these two distantly related fungal species...
  2. pmc Transcriptional profiling of a yeast colony provides new insight into the heterogeneity of multicellular fungal communities
    Ana Traven
    Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia
    PLoS ONE 7:e46243. 2012
    ....
  3. pmc Mitochondrial sorting and assembly machinery subunit Sam37 in Candida albicans: insight into the roles of mitochondria in fitness, cell wall integrity, and virulence
    Yue Qu
    Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, Australia
    Eukaryot Cell 11:532-44. 2012
    ..Beyond the relevance to fungal pathogenesis, this work also provides new insight into the mitochondrial and cellular roles of the SAM complex in fungi...
  4. pmc A model system for mitochondrial biogenesis reveals evolutionary rewiring of protein import and membrane assembly pathways
    Victoria L Hewitt
    Department of Biochemistry and Molecular Biology and Victorian Bioinformatics Consortium, Monash University, Melbourne, VIC 3800, Australia
    Proc Natl Acad Sci U S A 109:E3358-66. 2012
    ..We suggest that studies using this pathogen as a model system for mitochondrial biogenesis will greatly enhance our knowledge of how mitochondria are made and controlled through the course of the cell-division cycle...
  5. doi request reprint Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2
    Michael J Dagley
    Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia
    Mol Microbiol 79:968-89. 2011
    ..Moreover, in C. albicans also Sam37 is essential for caspofungin tolerance. Our study provides the basis for an integrative view of mitochondrial function in fungal cell wall biogenesis and resistance to echinocandin antifungal drugs...
  6. pmc The mRNA decay pathway regulates the expression of the Flo11 adhesin and biofilm formation in Saccharomyces cerevisiae
    Tricia L Lo
    Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia
    Genetics 191:1387-91. 2012
    ..We establish that the major mRNA decay pathway regulates FLO11 expression. mRNA deadenylation of transcriptional repressors of FLO11 by the exonuclease Ccr4 keeps their levels low, thereby allowing FLO11 transcription...
  7. doi request reprint The ins and outs of the intermembrane space: diverse mechanisms and evolutionary rewiring of mitochondrial protein import routes
    Victoria L Hewitt
    Department of Biochemistry and Molecular Biology, Building 77, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne 3800, Australia Electronic address
    Biochim Biophys Acta 1840:1246-53. 2014
    ..Examples of this process so far involve proteins destined to the mitochondrial intermembrane space (IMS)...
  8. pmc ifet-1 is a broad-scale translational repressor required for normal P granule formation in C. elegans
    Madhu S Sengupta
    Department of Biochemistry and Molecular Biology, Monash University, Victoria 3800, Australia
    J Cell Sci 126:850-9. 2013
    ..Our findings suggest that IFET-1 is a key translational regulator and is required for normal P granule formation...
  9. ncbi request reprint Guanylated polymethacrylates: a class of potent antimicrobial polymers with low hemolytic activity
    Katherine E S Locock
    CSIRO Materials Science and Engineering, Bayview Avenue, Clayton, Victoria 3168, Australia
    Biomacromolecules 14:4021-31. 2013
    ..In conclusion, a suite of guanidine copolymers has been identified that represent a new class of antimicrobial polymers with high potency and low toxicity. ..
  10. pmc Identification and mechanism of action of the plant defensin NaD1 as a new member of the antifungal drug arsenal against Candida albicans
    Brigitte M E Hayes
    La Trobe Institute for Molecular Science, Melbourne, Victoria, Australia
    Antimicrob Agents Chemother 57:3667-75. 2013
    ..albicans. ..
  11. pmc The yeast PUF protein Puf5 has Pop2-independent roles in response to DNA replication stress
    Ana Traven
    Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria, Australia
    PLoS ONE 5:e10651. 2010
    ..The Pop2-independent roles for Puf5 could involve spatial control of gene expression, a proposition supported by our data indicating that the active form of Puf5 is localised to cytoplasmic foci...
  12. pmc Mitochondria and fungal pathogenesis: drug tolerance, virulence, and potential for antifungal therapy
    Miguel Shingú-Vázquez
    Department of Biochemistry and Molecular Biology, Monash University, Clayton 3800, Victoria, Australia
    Eukaryot Cell 10:1376-83. 2011
    ..We discuss how the contrasting effects of mitochondrial dysfunction on fungal drug tolerance and virulence could be explained and the potential for targeting mitochondrial factors for future antifungal drug development...
  13. pmc ePAT: a simple method to tag adenylated RNA to measure poly(A)-tail length and other 3' RACE applications
    Amrei Jänicke
    Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia
    RNA 18:1289-95. 2012
    ....
  14. doi request reprint PUF proteins: repression, activation and mRNA localization
    Tara Quenault
    Department of Biochemistry and Molecular Biology, Monash University, Clayton, 3800 Victoria, Australia
    Trends Cell Biol 21:104-12. 2011
    ....
  15. doi request reprint A small Tim homohexamer in the relict mitochondrion of Cryptosporidium
    Felicity Alcock
    Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia
    Mol Biol Evol 29:113-22. 2012
    ..We show that the atypical CpTimS exists as a relatively unstable homohexamer, shedding light both on the early evolution of the small Tim protein family and on small Tim hexamer formation in contemporary eukaryotes...