Research Topics
| H J TeedeSummaryAffiliation: Monash Medical Centre Country: Australia Publications
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Publications
Dietary soy containing phytoestrogens does not have detectable estrogenic effects on hepatic protein synthesis in postmenopausal womenHelena J Teede
Vascular Research Group, Department of Medicine, Monash University, Clayton, Australia
Am J Clin Nutr 79:396-401. 2004..Dietary phytoestrogens are ligands for the estrogen receptor and may mimic estrogenic effects in vivo...
Effects of oral combined hormone replacement therapy on platelet aggregation in postmenopausal womenH J Teede
Vascular Medicine Unit, Department of Medicine, Dandenong Hospital, David St, Dandenong, Victoria 3175, Australia
Clin Sci (Lond) 100:207-13. 2001..The endogenous platelet nitric oxide system did not appear to affect aggregation in either group...
The menopause and HRT. Hormone replacement therapy, cardiovascular and cerebrovascular diseaseHelena J Teede
Monash University Department of Medicine, Vascular Medicine and Sciences Unit, Dandenong Hospital, David Street, Dandenong, Victoria 3175, Australia
Best Pract Res Clin Endocrinol Metab 17:73-90. 2003..However, the apparent lack of HRT effectiveness in the prevention of vascular disease should not deter enthusiasm for the use of established preventive therapies, especially lifestyle measures...
Dietary soy has both beneficial and potentially adverse cardiovascular effects: a placebo-controlled study in men and postmenopausal womenH J Teede
Cardiovascular Research Group, Department of Medicine, Monash University, Clayton
J Clin Endocrinol Metab 86:3053-60. 2001..Potential adverse effects were noted, with a decline in endothelial function (in males only) and an increase in Lp(a). Further research in hypertensive and hyperlipidemic populations is needed...
A placebo-controlled trial of long-term oral combined continuous hormone replacement therapy in postmenopausal women: effects on arterial compliance and endothelial functionH J Teede
Department of Medicine, Monash University, Dandenong Hospital, Victoria, Australia
Clin Endocrinol (Oxf) 55:673-82. 2001..To study the effects of long-term combined continuous oral hormone replacement therapy (HRT) on vascular function in healthy postmenopausal women...
Controversies in HRTHelena J Teede
Department of Medicine, Monash University
Aust Fam Physician 31:413-8. 2002..Short term hormone replacement therapy (HRT) use is well established for menopausal symptom relief. However, the rates and duration of HRT use are increasing in Australia while the benefits and risks of long term HRT remain controversial...
Isoflavones reduce arterial stiffness: a placebo-controlled study in men and postmenopausal womenHelena J Teede
Vascular Research Group, Department of Medicine, Monash University, Clayton, Australia
Arterioscler Thromb Vasc Biol 23:1066-71. 2003..This study was undertaken to address the vascular effects of isolated isoflavones as potential contributors to their cardioprotective properties, focusing on biochanin and formononetin...
Hormone replacement therapy and the prevention of cardiovascular diseaseHelena J Teede
Monash University Department of Medicine, Dandenong Hospital, Victoria, Australia
Hum Reprod Update 8:201-15. 2002....
Overweight women with polycystic ovary syndrome have evidence of subclinical cardiovascular diseaseC Meyer
Monash University Department of Medicine, Dandenong Hospital, Melbourne, Victoria 3175, Australia
J Clin Endocrinol Metab 90:5711-6. 2005..CONCLUSION: Overweight women with PCOS have increased cardiovascular risk factors and evidence of early CVD, compared with weight-matched controls, potentially related to IR...
Placebo-controlled trial of transdermal estrogen therapy alone in postmenopausal women: effects on arterial compliance and endothelial functionH J Teede
Department of Medicine, Monash University, Dandenong Hospital, Dandenong, Australia
Climacteric 5:160-9. 2002..These results would suggest that there might not be a beneficial effect of transdermal HRT on the vasculature in postmenopausal women...
Effect of exercise training on insulin sensitivity, mitochondria and computed tomography muscle attenuation in overweight women with and without polycystic ovary syndromeS K Hutchison
Jean Hailes Foundation Research, School of Public Health and Preventative Medicine, Monash University, Melbourne, Vic, Australia
Diabetologia 55:1424-34. 2012..We investigated whether differences in these variables explain the IR of women affected by PCOS and whether improvements in IR with exercise are reflected by changes in these variables...
Psychological parameters in the reproductive phenotypes of polycystic ovary syndromeL J Moran
Women s Public Health Research, School of Public Health and Preventive Medicine, Monash University, Clayton, Victoria 3168, Australia
Hum Reprod 27:2082-8. 2012..The aim of this study was to assess the psychological features in women with different polycystic ovary syndrome (PCOS) phenotypes [National Institute of Health (NIH) and non-NIH diagnostic criteria] and women without PCOS...
Hormone replacement therapy in postmenopausal women protects against smoking-induced changes in vascular structure and functionH J Teede
Department of Medicine, Monash University, Monash Medical Centre, Clayton, Victoria, Australia
J Am Coll Cardiol 34:131-7. 1999..The purpose of this study was to investigate the role of hormone replacement therapy (HRT) in postmenopausal women who smoke...
Vascular dysfunction and metabolic parameters in polycystic ovary syndromeC Meyer
Monash University Department of Medicine, Dandenong Hospital, Melbourne, Victoria, Australia
J Clin Endocrinol Metab 90:4630-5. 2005..DHEAS correlated inversely with arterial structure, suggesting possible cardioprotective effects of endogenous DHEAS in women with PCOS. Additional research is needed to clarify these findings...
Effects of combined oral hormone replacement therapy on tissue factor pathway inhibitor and factor VIIR E Peverill
Centre for Heart and Chest Research, Department of Medicine, Monash Medical Centre and Monash University, 246 Clayton Road, Clayton, Victoria 3168, Australia
Clin Sci (Lond) 101:93-9. 2001....
Sex hormones and the cardiovascular system: effects on arterial function in womenH J Teede
The Jean Hailes Foundation for Women s Health, Monash Institute for Health Services Research and Diabetes Unit, Southern Health, Melbourne, Victoria, Australia
Clin Exp Pharmacol Physiol 34:672-6. 2007..The data on arterial function reviewed herein, along with emerging interventional human studies, suggest that the cardiovascular effects of this practice are not adverse...
Obesity, metabolic complications and the menopause: an opportunity for preventionH J Teede
The Jean Hailes Foundation for Women s Health Research Group, Centre for Women s Health, Monash Institute of Medical Research, Clayton, Victoria
Climacteric 13:203-9. 2010..Accurate risk perception, education and translation programs highlighting obesity risks and supporting sustainable lifestyle changes are needed, particularly around menopause...
Novel inflammatory markers in overweight women with and without polycystic ovary syndrome and following pharmacological interventionL J Moran
The Jean Hailes Foundation for Women s Health, Monash Institute of Health Services Research, Monash University, Clayton, Victoria 3168, Australia
J Endocrinol Invest 33:258-65. 2010..Polycystic ovary syndrome (PCOS) is associated with reproductive and metabolic abnormalities...
Advanced chronic kidney disease, cardiovascular events and the effect of diabetes: data from the Atherosclerosis and Folic Acid Supplementation TrialS Zoungas
School of Public Health, Monash University, Melbourne, Victoria, Australia
Intern Med J 41:825-32. 2011..Here we examine whether diabetes is independently associated with an increased risk of major cardiovascular events and death in patients with advanced chronic kidney disease (CKD)...
Vascular dysfunction and autonomic neuropathy in Type 2 diabetesC Meyer
Monash University Department of Medicine, Dandenong Hospital, David Street, Dandenong, Victoria 3175, Australia
Diabet Med 21:746-51. 2004..This may help to explain the excess cardiovascular mortality seen in diabetic subjects with autonomic neuropathy...
Exercise decreases anti-müllerian hormone in anovulatory overweight women with polycystic ovary syndrome: a pilot studyL J Moran
The Jean Hailes Foundation for Women s Health Research Unit, School of Public Health and Preventive Medicine, Monash University, Clayton, Victoria, Australia
Horm Metab Res 43:977-9. 2011..2±11.7 pmol/l, p=0.025). Exercise is associated with improvements in ovarian hormones in women with abnormal ovarian function. This suggests that mechanisms associated with ovarian dysfunction can be improved by exercise in PCOS...
Fracture prevention strategies in patients presenting to Australian hospitals with minimal-trauma fractures: a major treatment gapH J Teede
Department of Endocrinology and Diabetes Southern Health, Monash Institute of Public Health Research, Melbourne, Victoria, Australia
Intern Med J 37:674-9. 2007..The aim of this study was to examine current fracture prevention strategies through the recognition, investigation and treatment of osteoporosis in patients presenting to acute hospitals with minimal-trauma fracture...
Is having polycystic ovary syndrome a predictor of poor psychological function including anxiety and depression?A A Deeks
The Jean Hailes Research Unit, School of Public Health and Preventive Medicine, Monash University, Locked Bag 29, Clayton, Victoria 3168, Australia
Hum Reprod 26:1399-407. 2011..We investigated factors associated with negative psychological functioning to determine whether they were predictive of anxiety and depression in PCOS...
Understanding health behaviours in a cohort of pregnant women at risk of gestational diabetes mellitus: an observational studyC L Harrison
School of Public Health and Preventive Medicine, Monash University, Clayton, Victoria, Australia
BJOG 119:731-8. 2012..To assess health behaviours, physical activity levels, weight gain and development of gestational diabetes mellitus (GDM) in high-risk women...
STOP fracture study: southern health osteoporotic fracture screening projectH J Teede
Jean Hailes Foundation for Women s Health Research Group, Monash University, Australia
Intern Med J 42:e74-9. 2012..Osteoporosis is a major healthcare issue with over 50% of postmenopausal women suffering an osteoporosis-related fracture. Vertebral fractures, the commonest, are often asymptomatic, unrecognised and untreated...
Hormone therapy--weighing up the evidenceHelena J Teede
Department of Medicine, Monash University, Victoria
Aust Fam Physician 33:875-80. 2004..Pharmacological therapy, with its inherent risks, even if small, should be reserved for high risk settings...
Menopause forum--a case discussion on midlife issuesHelena J Teede
The Jean Hailes Foundation, Melbourne, Victoria
Aust Fam Physician 33:903-5. 2004..The authors of our theme articles this month discuss their approach to the assessment and management of a woman presenting with issues relating to menopause and midlife...
Dietary soy containing phytoestrogens does not activate the hemostatic system in postmenopausal womenHelena J Teede
Cardiology Unit, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria, Australia
J Clin Endocrinol Metab 90:1936-41. 2005..In conclusion, the results of the current study do not support biologically significant estrogenic effects of soy/phytoestrogens on coagulation, fibrinolysis, or endothelial function...
Insulin-sensitisers in the treatment of polycystic ovary syndromeHelena J Teede
Jean Hailes Foundation, Monash Institute of Health Services Research, Monash Medical Centre, Level 1 Block E, Locked Bag 29 Clayton VIC 3168, Australia
Expert Opin Pharmacother 6:2419-27. 2005..Further research is needed to define the role of insulin sensitisers in PCOS and to determine the long-term risks and benefits of these therapies...
Randomised, controlled, cross-over trial of soy protein with isoflavones on blood pressure and arterial function in hypertensive subjectsHelena J Teede
Jean Hailes Research Group, Monash Institute of Health Services Research, Monash Medical Centre, Melbourne, Australia
J Am Coll Nutr 25:533-40. 2006....
The effects of soy protein containing isoflavones on lipids and indices of bone resorption in postmenopausal womenFabien S Dalais
Department of Epidemiology and Preventive Medicine, Monash University, The Alfred Hospital, Prahran, Australia
Clin Endocrinol (Oxf) 58:704-9. 2003..These findings suggest that soy may not have biologically significant oestrogenic effects on bone resorption and we hypothesize that the lipid effects may be mediated, at least in part, through nonoestrogenic mechanisms...
The impact of glycaemic control on outcomes in patients with end-stage renal disease and type 2 diabetesSophia Zoungas
Diabetes Clinical Services and Research Unit, Monash Medical Centre, Clayton, Victoria, Australia
Nephrology (Carlton) 13:124-7. 2008....
Oestrogen and the cardiovascular systemHelena J Teede
Department of Vascular Sciences and Medicine, Monash University, Dandenong Hospital, Dandenong, Victoria 3175, Australia
Clin Sci (Lond) 105:9-10. 2003
Relationship of waist and hip circumference with coagulation and fibrinolysis in postmenopausal womenRoger E Peverill
Monash Cardiovascular Research Centre, Southern Health and Monash University, Clayton, Victoria 3168, Australia
Clin Sci (Lond) 113:383-91. 2007..In contrast, a larger hip circumference appears to have a protective affect against coagulation activation...
