Jennifer M Rolland

Summary

Affiliation: Monash University
Country: Australia

Publications

  1. ncbi request reprint T cell targeted strategies for improved efficacy and safety of specific immunotherapy for allergic disease
    Jennifer M Rolland
    Department of Immunology, AMREP, Monash University, Commercial Road, Melbourne, VIC 3004, Australia
    Antiinflamm Antiallergy Agents Med Chem 12:201-22. 2013
  2. doi request reprint Unique and cross-reactive T cell epitope peptides of the major Bahia grass pollen allergen, Pas n 1
    Tamara Etto
    Department of Immunology, Monash University, Melbourne, Vic, Australia
    Int Arch Allergy Immunol 159:355-66. 2012
  3. doi request reprint TLR ligands of ryegrass pollen microbial contaminants enhance Th1 and Th2 responses and decrease induction of Foxp3(hi) regulatory T cells
    Diana Mittag
    Department of Immunology, Monash University, Melbourne, Australia
    Eur J Immunol 43:723-33. 2013
  4. doi request reprint Clinical allergy to hazelnut and peanut: identification of T cell cross-reactive allergens
    Ian N Glaspole
    Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Melbourne, Vic, Australia
    Int Arch Allergy Immunol 155:345-54. 2011
  5. doi request reprint The activin A antagonist follistatin inhibits asthmatic airway remodelling
    Charles Linton Hardy
    Department of Immunology, Monash University, Melbourne, Victoria, Australia
    Thorax 68:9-18. 2013
  6. doi request reprint House dust mite sublingual immunotherapy: the role for transforming growth factor-beta and functional regulatory T cells
    Robyn E O'Hehir
    Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Commercial Road, Melbourne, VIC 3004, Australia
    Am J Respir Crit Care Med 180:936-47. 2009
  7. doi request reprint Inert 50-nm polystyrene nanoparticles that modify pulmonary dendritic cell function and inhibit allergic airway inflammation
    Charles L Hardy
    Department of Immunology, Monash University, Melbourne, Victoria 3004, Australia
    J Immunol 188:1431-41. 2012
  8. doi request reprint Functional regulatory T cells and allergen immunotherapy
    Jennifer M Rolland
    Department of Immunology, Monash University, Melbourne, Victoria, Australia
    Curr Opin Allergy Clin Immunol 10:559-66. 2010
  9. doi request reprint Ara h 2 peptides containing dominant CD4+ T-cell epitopes: candidates for a peanut allergy therapeutic
    Sara R Prickett
    Department of Immunology, Monash University, Melbourne, Australia
    J Allergy Clin Immunol 127:608-15.e1-5. 2011
  10. doi request reprint The effector T cell response to ryegrass pollen is counterregulated by simultaneous induction of regulatory T cells
    Diana Mittag
    Department of Immunology, Monash University, Australia
    J Immunol 184:4708-16. 2010

Collaborators

Detail Information

Publications12

  1. ncbi request reprint T cell targeted strategies for improved efficacy and safety of specific immunotherapy for allergic disease
    Jennifer M Rolland
    Department of Immunology, AMREP, Monash University, Commercial Road, Melbourne, VIC 3004, Australia
    Antiinflamm Antiallergy Agents Med Chem 12:201-22. 2013
    ..T cell targeted strategies will facilitate wider clinical application of SIT and reliable laboratory assays for monitoring treatment. ..
  2. doi request reprint Unique and cross-reactive T cell epitope peptides of the major Bahia grass pollen allergen, Pas n 1
    Tamara Etto
    Department of Immunology, Monash University, Melbourne, Vic, Australia
    Int Arch Allergy Immunol 159:355-66. 2012
    ..T cell-reactive but IgE nonreactive peptides provide a safer treatment option. This study aimed to identify and characterize dominant CD4(+) T cell epitope peptides of the major BaGP allergen, Pas n 1...
  3. doi request reprint TLR ligands of ryegrass pollen microbial contaminants enhance Th1 and Th2 responses and decrease induction of Foxp3(hi) regulatory T cells
    Diana Mittag
    Department of Immunology, Monash University, Melbourne, Australia
    Eur J Immunol 43:723-33. 2013
    ..These findings show that adjuvants for specific immunotherapy should enhance Treg cells rather than target immune deviation from Th2 to Th1...
  4. doi request reprint Clinical allergy to hazelnut and peanut: identification of T cell cross-reactive allergens
    Ian N Glaspole
    Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Melbourne, Vic, Australia
    Int Arch Allergy Immunol 155:345-54. 2011
    ..Currently there is no cure. While co-allergy to peanut and tree nuts is a common clinical observation, and IgE cross-reactivity between peanut and tree nuts is reported, T cell cross-reactivity is poorly defined...
  5. doi request reprint The activin A antagonist follistatin inhibits asthmatic airway remodelling
    Charles Linton Hardy
    Department of Immunology, Monash University, Melbourne, Victoria, Australia
    Thorax 68:9-18. 2013
    ..The aim of this study was to test the potential of follistatin as a therapeutic agent to inhibit airway remodelling in an experimental model of chronic allergic airway inflammation...
  6. doi request reprint House dust mite sublingual immunotherapy: the role for transforming growth factor-beta and functional regulatory T cells
    Robyn E O'Hehir
    Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Commercial Road, Melbourne, VIC 3004, Australia
    Am J Respir Crit Care Med 180:936-47. 2009
    ..Sublingual allergen-specific immunotherapy is gaining popularity for treatment of allergic diseases, but underlying immunological mechanisms are unresolved...
  7. doi request reprint Inert 50-nm polystyrene nanoparticles that modify pulmonary dendritic cell function and inhibit allergic airway inflammation
    Charles L Hardy
    Department of Immunology, Monash University, Melbourne, Victoria 3004, Australia
    J Immunol 188:1431-41. 2012
    ..The discovery that a defined type of nanoparticle can inhibit, rather than promote, lung inflammation via modulation of DC function opens the door to the discovery of other nanoparticle types with exciting beneficial properties...
  8. doi request reprint Functional regulatory T cells and allergen immunotherapy
    Jennifer M Rolland
    Department of Immunology, Monash University, Melbourne, Victoria, Australia
    Curr Opin Allergy Clin Immunol 10:559-66. 2010
    ..This review examines evidence for functional Treg in controlling immune responses to allergen with particular focus on allergen-specific immunotherapy...
  9. doi request reprint Ara h 2 peptides containing dominant CD4+ T-cell epitopes: candidates for a peanut allergy therapeutic
    Sara R Prickett
    Department of Immunology, Monash University, Melbourne, Australia
    J Allergy Clin Immunol 127:608-15.e1-5. 2011
    ..Peanut allergy is a life-threatening condition; there is currently no cure. Although whole allergen extracts are used for specific immunotherapy for many allergies, they can cause severe reactions, and even fatalities, in peanut allergy...
  10. doi request reprint The effector T cell response to ryegrass pollen is counterregulated by simultaneous induction of regulatory T cells
    Diana Mittag
    Department of Immunology, Monash University, Australia
    J Immunol 184:4708-16. 2010
    ..These results indicate that the cogeneration of Foxp3(hi) Tregs in response to allergen may be a mechanism for controlling allergic reactions in healthy individuals, which is impaired in those with allergies...
  11. doi request reprint Interleukin-13 regulates secretion of the tumor growth factor-{beta} superfamily cytokine activin A in allergic airway inflammation
    Charles L Hardy
    Department of Immunology, Monash University, Commercial Road, Melbourne, VIC 3004 Australia
    Am J Respir Cell Mol Biol 42:667-75. 2010
    ..Given the immunomodulatory and fibrogenic effects of activin A, our findings suggest an important role for IL-13 regulation of activin A in asthma pathogenesis...
  12. doi request reprint Allergen-related approaches to immunotherapy
    Jennifer M Rolland
    Department of Immunology, Monash University, Commercial Road, Melbourne VIC 3004, Australia
    Pharmacol Ther 121:273-84. 2009
    ..Adjunct therapies such as anti-IgE antibody and corticosteroids may minimize the likelihood of adverse reactions in those with severe allergic disease who would most benefit from this treatment...