Jennifer M Rolland

Summary

Affiliation: Monash University
Country: Australia

Publications

  1. ncbi request reprint T cell targeted strategies for improved efficacy and safety of specific immunotherapy for allergic disease
    Jennifer M Rolland
    Department of Immunology, AMREP, Monash University, Commercial Road, Melbourne, VIC 3004, Australia
    Antiinflamm Antiallergy Agents Med Chem 12:201-22. 2013
  2. doi request reprint TLR ligands of ryegrass pollen microbial contaminants enhance Th1 and Th2 responses and decrease induction of Foxp3(hi) regulatory T cells
    Diana Mittag
    Department of Immunology, Monash University, Melbourne, Australia
    Eur J Immunol 43:723-33. 2013
  3. doi request reprint Differential uptake of nanoparticles and microparticles by pulmonary APC subsets induces discrete immunological imprints
    Charles L Hardy
    Department of Immunology, Monash University, Melbourne, Victoria 3004, Australia
    J Immunol 191:5278-90. 2013
  4. doi request reprint Clinical allergy to hazelnut and peanut: identification of T cell cross-reactive allergens
    Ian N Glaspole
    Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Melbourne, Vic, Australia
    Int Arch Allergy Immunol 155:345-54. 2011
  5. doi request reprint Unique and cross-reactive T cell epitope peptides of the major Bahia grass pollen allergen, Pas n 1
    Tamara Etto
    Department of Immunology, Monash University, Melbourne, Vic, Australia
    Int Arch Allergy Immunol 159:355-66. 2012
  6. doi request reprint The activin A antagonist follistatin inhibits asthmatic airway remodelling
    Charles Linton Hardy
    Department of Immunology, Monash University, Melbourne, Victoria, Australia
    Thorax 68:9-18. 2013
  7. doi request reprint Allergen-related approaches to immunotherapy
    Jennifer M Rolland
    Department of Immunology, Monash University, Commercial Road, Melbourne VIC 3004, Australia
    Pharmacol Ther 121:273-84. 2009
  8. doi request reprint House dust mite sublingual immunotherapy: the role for transforming growth factor-beta and functional regulatory T cells
    Robyn E O'Hehir
    Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Commercial Road, Melbourne, VIC 3004, Australia
    Am J Respir Crit Care Med 180:936-47. 2009
  9. ncbi request reprint Advances in development of hypoallergenic latex immunotherapy
    Jennifer M Rolland
    Cooperative Research Centre for Asthma, Sydney, New South Wales, and Department of Immunology, Monash University, Melbourne, Victoria, Australia
    Curr Opin Allergy Clin Immunol 5:544-51. 2005
  10. doi request reprint Interleukin-13 regulates secretion of the tumor growth factor-{beta} superfamily cytokine activin A in allergic airway inflammation
    Charles L Hardy
    Department of Immunology, Monash University, Commercial Road, Melbourne, VIC 3004 Australia
    Am J Respir Cell Mol Biol 42:667-75. 2010

Collaborators

Detail Information

Publications21

  1. ncbi request reprint T cell targeted strategies for improved efficacy and safety of specific immunotherapy for allergic disease
    Jennifer M Rolland
    Department of Immunology, AMREP, Monash University, Commercial Road, Melbourne, VIC 3004, Australia
    Antiinflamm Antiallergy Agents Med Chem 12:201-22. 2013
    ..T cell targeted strategies will facilitate wider clinical application of SIT and reliable laboratory assays for monitoring treatment. ..
  2. doi request reprint TLR ligands of ryegrass pollen microbial contaminants enhance Th1 and Th2 responses and decrease induction of Foxp3(hi) regulatory T cells
    Diana Mittag
    Department of Immunology, Monash University, Melbourne, Australia
    Eur J Immunol 43:723-33. 2013
    ..These findings show that adjuvants for specific immunotherapy should enhance Treg cells rather than target immune deviation from Th2 to Th1...
  3. doi request reprint Differential uptake of nanoparticles and microparticles by pulmonary APC subsets induces discrete immunological imprints
    Charles L Hardy
    Department of Immunology, Monash University, Melbourne, Victoria 3004, Australia
    J Immunol 191:5278-90. 2013
    ..These findings support the development of lung-specific particulate vaccines, drug delivery systems, and immunomodulators. ..
  4. doi request reprint Clinical allergy to hazelnut and peanut: identification of T cell cross-reactive allergens
    Ian N Glaspole
    Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Melbourne, Vic, Australia
    Int Arch Allergy Immunol 155:345-54. 2011
    ..Currently there is no cure. While co-allergy to peanut and tree nuts is a common clinical observation, and IgE cross-reactivity between peanut and tree nuts is reported, T cell cross-reactivity is poorly defined...
  5. doi request reprint Unique and cross-reactive T cell epitope peptides of the major Bahia grass pollen allergen, Pas n 1
    Tamara Etto
    Department of Immunology, Monash University, Melbourne, Vic, Australia
    Int Arch Allergy Immunol 159:355-66. 2012
    ..T cell-reactive but IgE nonreactive peptides provide a safer treatment option. This study aimed to identify and characterize dominant CD4(+) T cell epitope peptides of the major BaGP allergen, Pas n 1...
  6. doi request reprint The activin A antagonist follistatin inhibits asthmatic airway remodelling
    Charles Linton Hardy
    Department of Immunology, Monash University, Melbourne, Victoria, Australia
    Thorax 68:9-18. 2013
    ..The aim of this study was to test the potential of follistatin as a therapeutic agent to inhibit airway remodelling in an experimental model of chronic allergic airway inflammation...
  7. doi request reprint Allergen-related approaches to immunotherapy
    Jennifer M Rolland
    Department of Immunology, Monash University, Commercial Road, Melbourne VIC 3004, Australia
    Pharmacol Ther 121:273-84. 2009
    ..Adjunct therapies such as anti-IgE antibody and corticosteroids may minimize the likelihood of adverse reactions in those with severe allergic disease who would most benefit from this treatment...
  8. doi request reprint House dust mite sublingual immunotherapy: the role for transforming growth factor-beta and functional regulatory T cells
    Robyn E O'Hehir
    Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Commercial Road, Melbourne, VIC 3004, Australia
    Am J Respir Crit Care Med 180:936-47. 2009
    ..Sublingual allergen-specific immunotherapy is gaining popularity for treatment of allergic diseases, but underlying immunological mechanisms are unresolved...
  9. ncbi request reprint Advances in development of hypoallergenic latex immunotherapy
    Jennifer M Rolland
    Cooperative Research Centre for Asthma, Sydney, New South Wales, and Department of Immunology, Monash University, Melbourne, Victoria, Australia
    Curr Opin Allergy Clin Immunol 5:544-51. 2005
    ....
  10. doi request reprint Interleukin-13 regulates secretion of the tumor growth factor-{beta} superfamily cytokine activin A in allergic airway inflammation
    Charles L Hardy
    Department of Immunology, Monash University, Commercial Road, Melbourne, VIC 3004 Australia
    Am J Respir Cell Mol Biol 42:667-75. 2010
    ..Given the immunomodulatory and fibrogenic effects of activin A, our findings suggest an important role for IL-13 regulation of activin A in asthma pathogenesis...
  11. doi request reprint The effector T cell response to ryegrass pollen is counterregulated by simultaneous induction of regulatory T cells
    Diana Mittag
    Department of Immunology, Monash University, Australia
    J Immunol 184:4708-16. 2010
    ..These results indicate that the cogeneration of Foxp3(hi) Tregs in response to allergen may be a mechanism for controlling allergic reactions in healthy individuals, which is impaired in those with allergies...
  12. ncbi request reprint Anaphylaxis to lemon soap: citrus seed and peanut allergen cross-reactivity
    Ian N Glaspole
    Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Melbourne, Australia
    Ann Allergy Asthma Immunol 98:286-9. 2007
    ..Many individuals allergic to peanuts have multiple allergen sensitivity...
  13. doi request reprint Specific and sensitive enzyme-linked immunosorbent assays for analysis of residual allergenic food proteins in commercial bottled wine fined with egg white, milk, and nongrape-derived tannins
    Jennifer M Rolland
    Department of Immunology, Monash University, The Alfred, Commercial Road, Melbourne, Victoria, Australia 3004
    J Agric Food Chem 56:349-54. 2008
    ....
  14. doi request reprint Inert 50-nm polystyrene nanoparticles that modify pulmonary dendritic cell function and inhibit allergic airway inflammation
    Charles L Hardy
    Department of Immunology, Monash University, Melbourne, Victoria 3004, Australia
    J Immunol 188:1431-41. 2012
    ..The discovery that a defined type of nanoparticle can inhibit, rather than promote, lung inflammation via modulation of DC function opens the door to the discovery of other nanoparticle types with exciting beneficial properties...
  15. doi request reprint Ara h 2 peptides containing dominant CD4+ T-cell epitopes: candidates for a peanut allergy therapeutic
    Sara R Prickett
    Department of Immunology, Monash University, Melbourne, Australia
    J Allergy Clin Immunol 127:608-15.e1-5. 2011
    ..Peanut allergy is a life-threatening condition; there is currently no cure. Although whole allergen extracts are used for specific immunotherapy for many allergies, they can cause severe reactions, and even fatalities, in peanut allergy...
  16. ncbi request reprint High dose allergen stimulation of T cells from house dust mite-allergic subjects induces expansion of IFN-gamma+ T Cells, apoptosis of CD4+IL-4+ T cells and T cell anergy
    Leanne M Gardner
    Department of Pathology and Immunology, Monash University, Alfred Hospital, Melbourne, Vic, Australia
    Int Arch Allergy Immunol 133:1-13. 2004
    ....
  17. doi request reprint Functional regulatory T cells and allergen immunotherapy
    Jennifer M Rolland
    Department of Immunology, Monash University, Melbourne, Victoria, Australia
    Curr Opin Allergy Clin Immunol 10:559-66. 2010
    ..This review examines evidence for functional Treg in controlling immune responses to allergen with particular focus on allergen-specific immunotherapy...
  18. pmc MHC class II expression in human basophils: induction and lack of functional significance
    Astrid L Voskamp
    Department of Immunology, Monash University, Melbourne, Victoria, Australia Department of Allergy, Immunology and Respiratory Medicine, The Alfred Hospital and Monash University, Melbourne, Victoria, Australia
    PLoS ONE 8:e81777. 2013
    ....
  19. ncbi request reprint Characterization of a mouse model of allergy to a major occupational latex glove allergen Hev b 5
    Charles L Hardy
    Cooperative Research Centre for Asthma, Department of Pathology and Immunology, Monash Medical School, Commercial Road, Melbourne, VIC 3004, Australia
    Am J Respir Crit Care Med 167:1393-9. 2003
    ..This mouse model will aid the development of potentially curative treatments for latex-sensitized individuals, including those with occupational asthma...
  20. ncbi request reprint The peanut allergy epidemic: allergen molecular characterisation and prospects for specific therapy
    Maria P de Leon
    Department of Immunology, Monash University, Melbourne, Victoria 3004, Australia
    Expert Rev Mol Med 9:1-18. 2007
    ..These include T-cell-epitope peptide and hypoallergenic mutant vaccines. Alternative routes of administration such as sublingual are also considered, and appropriate adjuvants for delivering effective treatments at these sites examined...