D M Robertson

Summary

Affiliation: Monash University
Country: Australia

Publications

  1. ncbi request reprint Characterization of inhibin forms and their measurement by an inhibin alpha-subunit ELISA in serum from postmenopausal women with ovarian cancer
    D M Robertson
    Prince Henry s Institute of Medical Research, Clayton, Victoria 3168, Australia
    J Clin Endocrinol Metab 87:816-24. 2002
  2. ncbi request reprint Sensitive LH and FSH assays for monitoring low serum levels in men undergoing steroidal contraception
    D M Robertson
    Prince Henry s Institute of Medical Research, Monash Medical Centre, Clayton, Victoria, Australia
    Clin Endocrinol (Oxf) 55:331-9. 2001
  3. ncbi request reprint Development of an inhibin alpha subunit ELISA with broad specificity
    D M Robertson
    Prince Henry s Institute of Medical Research, P O Box 5152, VIC 3168, Clayton, Australia
    Mol Cell Endocrinol 180:79-86. 2001
  4. ncbi request reprint Inhibins/activins as diagnostic markers for ovarian cancer
    D M Robertson
    Prince Henry s Institute of Medical Research, PO Box 5152, Clayton, VIC 3168, Australia
    Mol Cell Endocrinol 191:97-103. 2002
  5. ncbi request reprint Reproductive hormones: ageing and the perimenopause
    David M Robertson
    Prince Henry s Institute of Medical Research, Monash Medical Center, Clayton, Victoria, Australia
    Acta Obstet Gynecol Scand 81:612-6. 2002
  6. ncbi request reprint Characterization of plasma inhibin forms in fertile and infertile men
    D M Robertson
    Prince Henry s Institute of Medical Research, PO Box 5152, Clayton, Victoria, 3168, Australia
    Hum Reprod 18:1047-54. 2003
  7. ncbi request reprint Inhibin/activin and ovarian cancer
    D M Robertson
    Prince Henry s Institute of Medical Research, PO 5152, Clayton, Victoria 3168, Australia
    Endocr Relat Cancer 11:35-49. 2004
  8. ncbi request reprint Combined inhibin and CA125 assays in the detection of ovarian cancer
    D M Robertson
    Prince Henry s Institute of Medical Research, Clayton, Victoria 3168, Australia
    Clin Chem 45:651-8. 1999
  9. ncbi request reprint Differential regulation of rat testicular 5alpha-reductase type 1 and 2 isoforms by testosterone and FSH
    K Pratis
    Prince Henry s Institute of Medical Research, PO Box 5152, Clayton, Victoria 3168, Australia
    J Endocrinol 176:393-403. 2003
  10. ncbi request reprint Effects of 31 kDa bovine inhibin on FSH and LH in rat pituitary cells in vitro: antagonism of gonadotrophin-releasing hormone agonists
    P G Farnworth
    Medical Research Centre, Prince Henry s Hospital, Melbourne, Victoria, Australia
    J Endocrinol 119:233-41. 1988

Collaborators

Detail Information

Publications58

  1. ncbi request reprint Characterization of inhibin forms and their measurement by an inhibin alpha-subunit ELISA in serum from postmenopausal women with ovarian cancer
    D M Robertson
    Prince Henry s Institute of Medical Research, Clayton, Victoria 3168, Australia
    J Clin Endocrinol Metab 87:816-24. 2002
    ..These new monoclonal antibody-based inhibin alphaC ELISAs now provide practical and sensitive assays suitable for evaluation as diagnostic tests for monitoring ovarian cancers...
  2. ncbi request reprint Sensitive LH and FSH assays for monitoring low serum levels in men undergoing steroidal contraception
    D M Robertson
    Prince Henry s Institute of Medical Research, Monash Medical Centre, Clayton, Victoria, Australia
    Clin Endocrinol (Oxf) 55:331-9. 2001
    ....
  3. ncbi request reprint Development of an inhibin alpha subunit ELISA with broad specificity
    D M Robertson
    Prince Henry s Institute of Medical Research, P O Box 5152, VIC 3168, Clayton, Australia
    Mol Cell Endocrinol 180:79-86. 2001
    ..A combination of Mabs in an ELISA was identified which provided data which matched that obtained with the alphaC IFMA and which may be useful as a replacement inhibin assay in clinical studies...
  4. ncbi request reprint Inhibins/activins as diagnostic markers for ovarian cancer
    D M Robertson
    Prince Henry s Institute of Medical Research, PO Box 5152, Clayton, VIC 3168, Australia
    Mol Cell Endocrinol 191:97-103. 2002
    ..Furthermore, based on the high sensitivity/specificity characteristics of the respective assays for the various types of ovarian cancer, the combination of the inhibin assay with CA125 detects the majority of all ovarian cancers...
  5. ncbi request reprint Reproductive hormones: ageing and the perimenopause
    David M Robertson
    Prince Henry s Institute of Medical Research, Monash Medical Center, Clayton, Victoria, Australia
    Acta Obstet Gynecol Scand 81:612-6. 2002
    ..Hormonal patterns during the luteal phase of the menstrual cycle also show changes with age but these changes are poorly understood...
  6. ncbi request reprint Characterization of plasma inhibin forms in fertile and infertile men
    D M Robertson
    Prince Henry s Institute of Medical Research, PO Box 5152, Clayton, Victoria, 3168, Australia
    Hum Reprod 18:1047-54. 2003
    ..The aim of this study was to establish if the inhibin B mol wt distribution was altered in men with infertility...
  7. ncbi request reprint Inhibin/activin and ovarian cancer
    D M Robertson
    Prince Henry s Institute of Medical Research, PO 5152, Clayton, Victoria 3168, Australia
    Endocr Relat Cancer 11:35-49. 2004
    ..In order to place these findings into perspective the biology of inhibin/activin and of other members of the TGFbeta superfamily is also discussed...
  8. ncbi request reprint Combined inhibin and CA125 assays in the detection of ovarian cancer
    D M Robertson
    Prince Henry s Institute of Medical Research, Clayton, Victoria 3168, Australia
    Clin Chem 45:651-8. 1999
    ....
  9. ncbi request reprint Differential regulation of rat testicular 5alpha-reductase type 1 and 2 isoforms by testosterone and FSH
    K Pratis
    Prince Henry s Institute of Medical Research, PO Box 5152, Clayton, Victoria 3168, Australia
    J Endocrinol 176:393-403. 2003
    ....
  10. ncbi request reprint Effects of 31 kDa bovine inhibin on FSH and LH in rat pituitary cells in vitro: antagonism of gonadotrophin-releasing hormone agonists
    P G Farnworth
    Medical Research Centre, Prince Henry s Hospital, Melbourne, Victoria, Australia
    J Endocrinol 119:233-41. 1988
    ..After a 3-day pretreatment, inhibin inhibited gonadotrophin release by buserelin less effectively than that by GnRH, but the pattern of antagonism was the same.(ABSTRACT TRUNCATED AT 250 WORDS)..
  11. ncbi request reprint Impairment of spermatogonial development and spermiation after testosterone-induced gonadotropin suppression in adult monkeys (Macaca fascicularis)
    L O'DONNELL
    Prince Henry s Institute of Medical Research, Clayton, Victoria 3168, Australia
    J Clin Endocrinol Metab 86:1814-22. 2001
    ....
  12. ncbi request reprint Inhibin binding sites and proteins in pituitary, gonadal, adrenal and bone cells
    P G Farnworth
    Prince Henry s Institute of Medical Research, P O Box 5152, 3168, Victoria, Clayton, Australia
    Mol Cell Endocrinol 180:63-71. 2001
    ..Novel inhibin binding proteins of around 41 and 124 kDa were implicated in the high affinity binding of inhibin to cells from several sources...
  13. ncbi request reprint Temporal and hormonal regulation of inhibin protein and subunit mRNA expression by post-natal and immature rat ovaries
    A E Drummond
    Prince Henry s Institute of Medical Research, PO Box 5152, Clayton, Victoria 3168, Australia
    J Endocrinol 166:339-54. 2000
    ....
  14. ncbi request reprint Inhibin forms in serum from postmenopausal women with ovarian cancers
    D M Robertson
    Prince Henry s Institute of Medical Research, Clayton, Victoria, Australia
    Clin Endocrinol (Oxf) 50:381-6. 1999
    ..The aim of the study was to identify the forms of inhibin found in a range of ovarian cancers using a range of inhibin assays with varying specificities...
  15. ncbi request reprint Identification of specific sites of hormonal regulation in spermatogenesis in rats, monkeys, and man
    R I McLachlan
    Prince Henry s Institute of Medical Research, Monash Medical Centre, Clayton, Victoria, Australia
    Recent Prog Horm Res 57:149-79. 2002
    ..These concepts are also discussed in the context of male hormonal contraceptive development...
  16. ncbi request reprint The inhibins and ovarian cancer
    H G Burger
    Prince Henry s Institute of Medical Research, PO Box 5152, VIC 3168, Clayton, Australia
    Mol Cell Endocrinol 180:145-8. 2001
    ..Findings to date have been largely negative with no evidence for activating mutations of the FSH receptor or of the post-receptor signalling pathway proteins...
  17. ncbi request reprint Production and actions of inhibin and activin during folliculogenesis in the rat
    J K Findlay
    Prince Henry s Institute of Medical Research, P O Box 5152, VIC 3168, Clayton, Australia
    Mol Cell Endocrinol 180:139-44. 2001
    ..Our hypothesis that inhibin and activin play important and changing autocrine/paracrine roles in the growth and differentiation of follicles, including the oocyte, has been supported by these studies...
  18. ncbi request reprint The roles of activins, inhibins and estrogen in early committed follicles
    J K Findlay
    Prince Henry s Institute of Medical Research, P O Box 5152, VIC 3168, Clayton, Australia
    Mol Cell Endocrinol 163:81-7. 2000
    ..These data are consistent with autocrine/paracrine actions of activin in the early growth of committed follicles and estrogen in follicular maturation...
  19. ncbi request reprint Placental, maternal serum and amniotic fluid molecular weight forms of inhibin A and pro-alphaC
    P Thirunavukarasu
    Prince Henry s Institute of Medical Research, Southern Health, Clayton, Victoria, 3168, Australia
    Placenta 24:370-7. 2003
    ..We conclude that inhibin A and pro-alphaC inhibins in maternal serum are processed in late pregnancy by more than one mechanism to form low mol wt circulating forms of, as yet, undetermined structure...
  20. ncbi request reprint Identification of specific inhibin A-binding proteins on mouse Leydig (TM3) and sertoli (TM4) cell lines
    C A Harrison
    Prince Henry's Institute of Medical Research, Clayton 3168, Victoria, Australia
    Endocrinology 142:1393-402. 2001
    ..It is concluded that the high affinity binding complex for inhibin A found in these cell lines consists of betaglycan and several proteins of unknown identity and may represent the putative inhibin receptor complex...
  21. ncbi request reprint Efficacy and acceptability of testosterone implants, alone or in combination with a 5alpha-reductase inhibitor, for male hormonal contraception
    R I McLachlan
    Prince Henry s Institute of Medical Research, Monash Medical Centre, Clayton Road, Clayton, Victoria, Australia
    Contraception 62:73-8. 2000
    ....
  22. ncbi request reprint A review of hormonal changes during the menopausal transition: focus on findings from the Melbourne Women's Midlife Health Project
    H G Burger
    Prince Henry s Institute of Medical Research, Monash Medical Centre, Clayton, Victoria, Australia
    Hum Reprod Update 13:559-65. 2007
    ..This review provides the background for an accompanying manuscript in which a novel approach to modelling the hormonal changes during the transition is described...
  23. ncbi request reprint Effects of bovine 35 kDa FSH-suppressing protein on FSH and LH in rat pituitary cells in vitro: comparison with bovine 31 kDa inhibin
    D M Robertson
    Department of Anatomy, Monash University, Clayton, Victoria, Australia
    J Endocrinol 124:417-23. 1990
    ..The effect of FSP on FSH cell content after 3 days in culture was insensitive to the neutralizing effects of an inhibin antiserum.(ABSTRACT TRUNCATED AT 250 WORDS)..
  24. ncbi request reprint Sertoli cell ectoplasmic specializations in the seminiferous epithelium of the testosterone-suppressed adult rat
    L O'DONNELL
    Prince Henry s Institute of Medical Research, Monash Medical Centre, Clayton, Victoria 3168, Australia
    Biol Reprod 63:99-108. 2000
    ..We suggest that defects in adhesion molecules between round spermatids and Sertoli cells are likely to be involved in the testosterone-dependent detachment of round spermatids from the seminiferous epithelium...
  25. ncbi request reprint Both inhibin A and B respond to exogenous follicle-stimulating hormone in the follicular phase of the human menstrual cycle
    H G Burger
    Prince Henry s Institute of Medical Research, Monash Medical Center, Clayton, Victoria, Australia
    J Clin Endocrinol Metab 83:4167-9. 1998
    ....
  26. ncbi request reprint Molecular weight forms of inhibin A, inhibin B and pro-alphaC in maternal serum, amniotic fluid and placental extracts of normal and Down syndrome pregnancies
    P P Thirunavukarasu
    Centre for Women s Health Research, Monash University, Clayton, Victoria, Australia
    Prenat Diagn 22:1086-92. 2002
    ..The present study explored whether specific inhibin A isoforms may be selectively increased in DS, offering the prospect of improved marker performance...
  27. ncbi request reprint Serum immunoactive inhibin levels in early pregnancy after in vitro fertilization and embryo transfer
    T Yohkaichiya
    Monash University, Prince Henry s Institute of Medical Research, Monash Medical Centre, Melbourne, Victoria, Australia
    Fertil Steril 59:1081-9. 1993
    ..To determine the maternal serum concentrations of inhibin, E2, P, and hCG in early pregnancies arising from IVF and ET or GIFT and to assess the value of these hormone measurements in determining outcome of pregnancy...
  28. ncbi request reprint Activins and inhibins in endocrine and other tumors
    G P Risbridger
    Centre for Urological Research, Institute of Reproduction and Development, Monash University, Melbourne, Victoria 3168, Australia
    Endocr Rev 22:836-58. 2001
    ..Future studies will define the mechanisms by which inhibins and activins contribute to the process of initiation, promotion, or progression of endocrine-related cancers...
  29. ncbi request reprint Pachytene spermatocytes in co-culture inhibit rat Sertoli cell synthesis of inhibin beta B-subunit and inhibin B but not the inhibin alpha-subunit
    R J Clifton
    Department of Obstetrics and Gynecology, Monash University, Clayton 3168, Victoria, Australia
    J Endocrinol 172:565-74. 2002
    ..These findings support the hypothesis that specific germ cell types can influence inhibin B secretion by the testis independent of FSH regulation...
  30. ncbi request reprint Testosterone withdrawal promotes stage-specific detachment of round spermatids from the rat seminiferous epithelium
    L O'DONNELL
    Prince Henry s Institute of Medical Research, Monash Medical Centre, Clayton, Australia
    Biol Reprod 55:895-901. 1996
    ..We conclude that the failure of round spermatids to complete spermiogenesis following T withdrawal is due to stage-specific detachment of round spermatids between stages VII and VIII...
  31. ncbi request reprint Loss of the expression and localization of inhibin alpha-subunit in high grade prostate cancer
    S L Mellor
    Institute of Reproduction and Development, Monash Medical Center, Clayton, Victoria, Australia
    J Clin Endocrinol Metab 83:969-75. 1998
    ..These results demonstrate that in contrast to ovarian granulosa cell tumors, inhibin alpha gene expression is down-regulated in poorly differentiated prostate cancer...
  32. ncbi request reprint Recruitment and development of the follicle; the roles of the transforming growth factor-beta superfamily
    J K Findlay
    Prince Henry s Institute of Medical Research, P O Box 5152, Clayton, VIC 3168, Australia
    Mol Cell Endocrinol 191:35-43. 2002
    ....
  33. ncbi request reprint Rodent adrenocortical cells display high affinity binding sites and proteins for inhibin A, and express components required for autocrine signalling by activins and bone morphogenetic proteins
    Paul G Farnworth
    Prince Henry s Institute of Medical Research, PO Box 5152, Clayton, 3168 Victoria, Australia
    J Endocrinol 188:451-65. 2006
    ....
  34. ncbi request reprint Oestrogen does not affect the restoration of spermatogenesis in the gonadotrophin-releasing hormone-immunised adult rat
    Sarah J Meachem
    Prince Henry s Institute of Medical Research Block E, Level 4, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia
    J Endocrinol 185:529-38. 2005
    ..Co-administration of ICI 182780 had no effect on any of these germ cell numbers. We conclude that oestrogen action plays no role in the short-term restoration of spermatogenesis by testosterone in the GnRH-immunised rat...
  35. ncbi request reprint The relative roles of follicle-stimulating hormone and luteinizing hormone in maintaining spermatogonial maturation and spermiation in normal men
    Kati L Matthiesson
    Prince Henry s Institute, and Departments of Obstetrics and Gynaecology, Monash University, P O Box 5152, Monash Medical Center, Clayton, Victoria 3168, Australia
    J Clin Endocrinol Metab 91:3962-9. 2006
    ..Male hormonal contraception via gonadotropin and intratesticular androgen withdrawal disrupts spermatogenesis at two principal sites: 1) spermatogonial maturation, and 2) spermiation...
  36. ncbi request reprint Inhibin as a diagnostic marker for ovarian cancer
    David M Robertson
    Prince Henry s Institute of Medical Research, P O Box 5152, Clayton, 3168 Vic, Australia
    Cancer Lett 249:14-7. 2007
    ..In some published studies, the two markers together have detected up to 95% of ovarian cancers with 95% specificity...
  37. ncbi request reprint A complex containing alpha6beta1-integrin and phosphorylated focal adhesion kinase between Sertoli cells and elongated spermatids during spermatid release from the seminiferous epithelium
    Amanda Beardsley
    Prince Henry s Institute of Medical Research, Monash Medical Centre, Clayton, Victoria 3168, Australia
    J Endocrinol 190:759-70. 2006
    ..We conclude that spermatid release during spermiation is mediated by a 'disengagement complex' containing alpha(6)beta(1)-integrin and phospho-FAK, the function of which can be affected by gonadotrophin suppression...
  38. ncbi request reprint Inhibin A and B in vitro bioactivities are modified by their degree of glycosylation and their affinities to betaglycan
    Yogeshwar Makanji
    Prince Henry s Institute of Medical Research, Monash University, PO Box 5152, Clayton, Victoria 3168, Australia
    Endocrinology 148:2309-16. 2007
    ..It is concluded that glycosylation of Asn(302) of the alpha-subunit of inhibin A and B results in a decrease in bioactivity, and the effect on inhibin A, at least, is explained by its reduced affinity to betaglycan...
  39. doi request reprint Cycle and hormone changes during perimenopause: the key role of ovarian function
    Henry G Burger
    Prince Henry s Institute of Medical Research, Monash Medical Centre, Clayton, Victoria, Australia
    Menopause 15:603-12. 2008
    ..There is no specific endocrine marker of the early or late transition, making measurements of FSH or E2 unreliable in attempting to stage an individual with regard to approaching menopause...
  40. ncbi request reprint Endocrine features of menstrual cycles in middle and late reproductive age and the menopausal transition classified according to the Staging of Reproductive Aging Workshop (STRAW) staging system
    Georgina E Hale
    Department of Obstetrics and Gynecology, University of Sydney, New South Wales, Australia 2006
    J Clin Endocrinol Metab 92:3060-7. 2007
    ..Female reproductive aging based on changes in menstrual cycle length and frequency progresses through a number of stages as defined by the Stages of Reproductive Aging Workshop (STRAW) staging criteria...
  41. doi request reprint Suppression of inhibin A biological activity by alterations in the binding site for betaglycan
    Yogeshwar Makanji
    Prince Henry s Institute of Medical Research, Clayton, Victoria 3168, Australia
    J Biol Chem 283:16743-51. 2008
    ..Together these results indicate that a high affinity interaction between betaglycan and residues Val(108)-Tyr(120) of the inhibin alpha-subunit mediate inhibin A biological activity...
  42. ncbi request reprint Functional analysis of the human inhibin alpha subunit variant A257T and its potential role in premature ovarian failure
    Ashwini L Chand
    Prince Henry s Institute of Medical Research, PO Box 5152, Clayton, Victoria 3168, Australia
    Hum Reprod 22:3241-8. 2007
    ..We hypothesize this mutation causes a reduction in inhibin bioactivity, removing its suppression on the pituitary FSH secretion. The aim of this study is to establish if A257T inhibin has reduced bioactivity...
  43. ncbi request reprint The relationship between the endocrine characteristics and the regularity of menstrual cycles in the approach to menopause
    Henry G Burger
    Prince Henry s Institute of Medical Research, Clayton, Victoria, Australia
    Menopause 12:267-74. 2005
    ..We sought to determine whether the onset of irregular menses, marking the menopause transition, signifies the occurrence of anovulatory, potentially infertile cycles...
  44. ncbi request reprint Antagonists of activin signaling: mechanisms and potential biological applications
    Craig A Harrison
    Prince Henry s Institute of Medical Research, 246 Clayton Road, Clayton, VIC 3168, Australia
    Trends Endocrinol Metab 16:73-8. 2005
    ..Understanding how activin signaling is controlled extracellularly is the first step in providing treatment for wound healing and for disorders such as cachexia and cancer, which result from a deregulated activin pathway...
  45. ncbi request reprint Inhibins and ovarian cancer
    David M Robertson
    Prince Henry s Institute of Medical Research, Monash Medical Centre, P O Box 5152, Clayton, VIC 3168, Australia
    Mol Cell Endocrinol 225:65-71. 2004
    ..These studies are providing a platform for the introduction of the test into clinical practice...
  46. ncbi request reprint Effects of testosterone plus medroxyprogesterone acetate on semen quality, reproductive hormones, and germ cell populations in normal young men
    Robert I McLachlan
    Prince Henry s Institute of Medical Research, Monash Medical Centre, Clayton, Victoria, Australia 3168
    J Clin Endocrinol Metab 87:546-56. 2002
    ....
  47. ncbi request reprint Hormonal regulation of spermatogenesis in primates and man: insights for development of the male hormonal contraceptive
    Robert I McLachlan
    Prince Henry s Institute of Medical Research, Monash Medical Centre, Clayton, Victoria, Australia
    J Androl 23:149-62. 2002
  48. ncbi request reprint Hormonal changes in the menopause transition
    Henry G Burger
    Prince Henry s Institute of Medical Research at Monash Medical Centre, Clayton, Victoria, Australia
    Recent Prog Horm Res 57:257-75. 2002
    ....
  49. ncbi request reprint Variability in sperm suppression during testosterone administration to adult monkeys is related to follicle stimulating hormone suppression and not to intratesticular androgens
    Anita Narula
    Population Center for Research in Reproduction, Department of Medicine, University of Washington, Seattle, WA 98195, USA
    J Clin Endocrinol Metab 87:3399-406. 2002
    ....
  50. ncbi request reprint 5alpha-reductase isoenzymes 1 and 2 in the rat testis during postnatal development
    Jessica Killian
    Prince Henry s Institute of Medical Research, Clayton, Victoria 3168, Australia
    Biol Reprod 68:1711-8. 2003
    ..We conclude that both 5alphaR1 and 5alphaR2 isoenzymes are involved in the peak of 5alpha-reduced androgen biosynthesis in the testis during the pubertal initiation of spermatogenesis...
  51. ncbi request reprint Sertoli-Leydig cell tumor of the ovary, a rare cause of precocious puberty in a 12-month-old infant
    Catherine S Choong
    Department of Pediatric Endocrinology, Mater Misericordiae Hospitals, South Brisbane, Queensland 4104, Australia
    J Clin Endocrinol Metab 87:49-56. 2002
    ....
  52. ncbi request reprint Response of serum inhibin B and pro-alphaC levels to gonadotrophic stimulation in normal men before and after steroidal contraceptive treatment
    Kati L Matthiesson
    Prince Henry s Institute of Medical Research, Monash Medical Centre, Monash University, Clayton, Victoria 3168, Australia
    Hum Reprod 18:734-43. 2003
    ..Testicular regulation of inhibin B may be influenced by the germ cell complement...
  53. ncbi request reprint Relationship between serum gonadotropins and spermatogenic suppression in men undergoing steroidal contraceptive treatment
    Robert I McLachlan
    Prince Henry s Institute of Medical Research, Monash Medical Center, Clayton, Victoria 3168, Australia
    J Clin Endocrinol Metab 89:142-9. 2004
    ..On the other hand, the greater spermatogenic suppression in regimens containing DSG or CPA suggests that these progestins have additional actions to suppress spermatogenesis via a gonadotropin-independent mechanism(s)..
  54. ncbi request reprint Menopause transition: Annual changes in serum hormonal patterns over the menstrual cycle in women during a nine-year period prior to menopause
    Britt Marie Landgren
    Department of Clinical Science, Division of Obstetrics and Gynaecology, Karolinska Institutet, Huddinge University Hospital, SE 14186 Stockholm, Sweden
    J Clin Endocrinol Metab 89:2763-9. 2004
    ..The data amplify and clarify current concepts of the endocrine basis of the menopause transition...
  55. ncbi request reprint Activin-A binds follistatin and type II receptors through overlapping binding sites: generation of mutants with isolated binding activities
    Craig A Harrison
    Prince Henry s Institute of Medical Research, Clayton, Victoria 3168, Australia
    Endocrinology 147:2744-53. 2006
    ..These reagents could be used to modulate follistatin antagonism of activin and related ligands in processes such as cancer, wound healing, and reproduction...
  56. ncbi request reprint Activin A and inhibin A differentially regulate human uterine matrix metalloproteinases: potential interactions during decidualization and trophoblast invasion
    Rebecca L Jones
    Prince Henry s Institute of Medical Research, Clayton, Victoria, Australia
    Endocrinology 147:724-32. 2006
    ..This suggests that inhibin may have a role in the cessation of vascular invasion. These data support that activin, via effects on MMPs, is an important factor in the maternal-fetal dialog regulating implantation...
  57. ncbi request reprint Inhibins as biomarkers for reproductive cancers
    David M Robertson
    Prince Henry s Institute of Medical Research and Department of Obstetrics and Gynecology, Monash University, Clayton, Victoria, Australia
    Semin Reprod Med 22:219-25. 2004
    ..Although serum inhibins are elevated in prostatic and testicular cancers, this is of little diagnostic value at the present time...
  58. ncbi request reprint Serum inhibin A and B concentrations during the menstrual cycle in mothers of spontaneous dizygotic twins
    Christopher P Gilfillan
    Prince Henry s Institute of Medical Research, Clayton, Victoria, Australia
    Twin Res 6:27-33. 2003
    ..These data suggest that the genetic cause of twinning is not associated with changes in FSH concentrations or recognised feedback mechanisms regulating FSH release...