Paul E O'Brien

Summary

Affiliation: Monash University
Country: Australia

Publications

  1. doi request reprint Intensive medical weight loss or laparoscopic adjustable gastric banding in the treatment of mild to moderate obesity: long-term follow-up of a prospective randomised trial
    Paul E O'Brien
    Centre for Obesity Research and Education, Monash University, Melbourne, Australia
    Obes Surg 23:1345-53. 2013
  2. doi request reprint Long-term outcomes after bariatric surgery: fifteen-year follow-up of adjustable gastric banding and a systematic review of the bariatric surgical literature
    Paul E O'Brien
    Centre for Obesity Research and Education CORE, Monash University, Melbourne, Victoria, Australia
    Ann Surg 257:87-94. 2013
  3. doi request reprint Bariatric surgery: mechanisms, indications and outcomes
    Paul E O'Brien
    Centre for Obesity Research and Education, Monash University, The Alfred Hospital, Melbourne, Victoria, Australia
    J Gastroenterol Hepatol 25:1358-65. 2010
  4. doi request reprint Pathophysiology of laparoscopic adjustable gastric bands: analysis and classification using high-resolution video manometry and a stress barium protocol
    Paul Robert Burton
    Centre for Obesity Research and Education, Monash University, Melbourne, Australia
    Obes Surg 20:19-29. 2010
  5. ncbi request reprint Sustained weight loss in obese subjects has benefits that are independent of attained weight
    John B Dixon
    Monash University Department of Surgery, Alfred Hospital, Melbourne, Victoria 3181, Australia
    Obes Res 12:1895-902. 2004
  6. doi request reprint The effect of laparoscopic adjustable gastric bands on esophageal motility and the gastroesophageal junction: analysis using high-resolution video manometry
    Paul R Burton
    Centre for Obesity Research and Education, Monash University, The Alfred Hospital, Melbourne, 3004, Victoria, Australia
    Obes Surg 19:905-14. 2009
  7. doi request reprint Criteria for assessing esophageal motility in laparoscopic adjustable gastric band patients: the importance of the lower esophageal contractile segment
    Paul Robert Burton
    Centre for Obesity Research and Education CORE, Monash Medical School, The Alfred Hospital, Commercial RD Prahran, 3181, Melbourne, Australia
    Obes Surg 20:316-25. 2010
  8. doi request reprint Laparoscopic adjustable gastric banding in severely obese adolescents: a randomized trial
    Paul E O'Brien
    Centre for Obesity Research and Education, Monash University Medical School, Alfred Hospital, Melbourne, 3004, Australia
    JAMA 303:519-26. 2010
  9. doi request reprint Effects of adjustable gastric bands on gastric emptying, supra- and infraband transit and satiety: a randomized double-blind crossover trial using a new technique of band visualization
    Paul Robert Burton
    Centre for Obesity Research and Education CORE, Monash University, The Alfred Hospital, Melbourne, Australia
    Obes Surg 20:1690-7. 2010
  10. doi request reprint Outcomes, satiety, and adverse upper gastrointestinal symptoms following laparoscopic adjustable gastric banding
    Paul R Burton
    Centre for Obesity Research and Education CORE, Monash University, Melbourne, Australia
    Obes Surg 21:574-81. 2011

Detail Information

Publications74

  1. doi request reprint Intensive medical weight loss or laparoscopic adjustable gastric banding in the treatment of mild to moderate obesity: long-term follow-up of a prospective randomised trial
    Paul E O'Brien
    Centre for Obesity Research and Education, Monash University, Melbourne, Australia
    Obes Surg 23:1345-53. 2013
    ..Proven short-term effectiveness of obesity therapy should be re-evaluated in the long-term. The objective of this paper is to determine the long-term (10 years) outcome for patients from a randomised controlled trial (RCT)...
  2. doi request reprint Long-term outcomes after bariatric surgery: fifteen-year follow-up of adjustable gastric banding and a systematic review of the bariatric surgical literature
    Paul E O'Brien
    Centre for Obesity Research and Education CORE, Monash University, Melbourne, Victoria, Australia
    Ann Surg 257:87-94. 2013
    ..To describe the long-term outcomes after laparoscopic adjustable gastric banding (LAGB) and compare these with the published literature on bariatric surgery...
  3. doi request reprint Bariatric surgery: mechanisms, indications and outcomes
    Paul E O'Brien
    Centre for Obesity Research and Education, Monash University, The Alfred Hospital, Melbourne, Victoria, Australia
    J Gastroenterol Hepatol 25:1358-65. 2010
    ..Gastric bypass or biliopancreatic diversion should be considered in those with BMI greater than 35 if banding is contraindicated or has been unsuccessful...
  4. doi request reprint Pathophysiology of laparoscopic adjustable gastric bands: analysis and classification using high-resolution video manometry and a stress barium protocol
    Paul Robert Burton
    Centre for Obesity Research and Education, Monash University, Melbourne, Australia
    Obes Surg 20:19-29. 2010
    ..There is a need for a better understanding of the pathophysiology of LAGBs and more sensitive diagnostic tests...
  5. ncbi request reprint Sustained weight loss in obese subjects has benefits that are independent of attained weight
    John B Dixon
    Monash University Department of Surgery, Alfred Hospital, Melbourne, Victoria 3181, Australia
    Obes Res 12:1895-902. 2004
    ..To explore the hypothesis that sustained weight loss in severely obese patients may have benefits that are independent of their attained BMI...
  6. doi request reprint The effect of laparoscopic adjustable gastric bands on esophageal motility and the gastroesophageal junction: analysis using high-resolution video manometry
    Paul R Burton
    Centre for Obesity Research and Education, Monash University, The Alfred Hospital, Melbourne, 3004, Victoria, Australia
    Obes Surg 19:905-14. 2009
    ..Conflicting data exist concerning their effect on the esophagus, gastroesophageal junction, and mechanism of action. These patients will increasingly require accurate assessment of their esophageal function...
  7. doi request reprint Criteria for assessing esophageal motility in laparoscopic adjustable gastric band patients: the importance of the lower esophageal contractile segment
    Paul Robert Burton
    Centre for Obesity Research and Education CORE, Monash Medical School, The Alfred Hospital, Commercial RD Prahran, 3181, Melbourne, Australia
    Obes Surg 20:316-25. 2010
    ..Recent combined video fluoroscopic and high-resolution manometric studies have identified important components of esophageal function in LAGB patients...
  8. doi request reprint Laparoscopic adjustable gastric banding in severely obese adolescents: a randomized trial
    Paul E O'Brien
    Centre for Obesity Research and Education, Monash University Medical School, Alfred Hospital, Melbourne, 3004, Australia
    JAMA 303:519-26. 2010
    ..Bariatric surgery is being evaluated as a possible treatment option. Laparoscopic adjustable gastric banding (gastric banding) has the potential to provide a safe and effective treatment...
  9. doi request reprint Effects of adjustable gastric bands on gastric emptying, supra- and infraband transit and satiety: a randomized double-blind crossover trial using a new technique of band visualization
    Paul Robert Burton
    Centre for Obesity Research and Education CORE, Monash University, The Alfred Hospital, Melbourne, Australia
    Obes Surg 20:1690-7. 2010
    ..Recently, the key mechanism has been hypothesized to be the induction of satiety without restriction. Effects can be controlled by modifying LAGB volume, possibly as a result of effects on gastric emptying or transit through the LAGB...
  10. doi request reprint Outcomes, satiety, and adverse upper gastrointestinal symptoms following laparoscopic adjustable gastric banding
    Paul R Burton
    Centre for Obesity Research and Education CORE, Monash University, Melbourne, Australia
    Obes Surg 21:574-81. 2011
    ..Follow-up is critical to the success of laparoscopic adjustable gastric banding (LAGB). Few data guide this and expected norms of satiety, adverse symptoms, and outcomes have not been defined...
  11. doi request reprint Loss of control is central to psychological disturbance associated with binge eating disorder
    Susan L Colles
    Centre for Obesity Research and Education CORE, Monash University, The Alfred Hospital, Melbourne, Victoria, Australia
    Obesity (Silver Spring) 16:608-14. 2008
    ..The primary aim of this study was to investigate which core behavioral features of binge eating are most strongly related to psychological disturbance...
  12. doi request reprint Motivation, readiness to change, and weight loss following adjustable gastric band surgery
    John B Dixon
    Centre for Obesity Research and Education, Monash University, Victoria, Australia
    Obesity (Silver Spring) 17:698-705. 2009
    ..Measures of RTC did not predict weight loss, compliance, or surgical complications. Caution is advised when using assessments of RTC to predict outcomes of bariatric surgery...
  13. ncbi request reprint Treatment of mild to moderate obesity with laparoscopic adjustable gastric banding or an intensive medical program: a randomized trial
    Paul E O'Brien
    Centre for Obesity Research and Education, Monash University Medical School, The Alfred Hospital, Melbourne, Victoria, Australia
    Ann Intern Med 144:625-33. 2006
    ..Obesity is a major, growing health problem. Observational studies suggest that bariatric surgery is more effective than nonsurgical therapy, but no randomized, controlled trials have confirmed this...
  14. ncbi request reprint Weight loss and non-alcoholic fatty liver disease: falls in gamma-glutamyl transferase concentrations are associated with histologic improvement
    John B Dixon
    Centre for Obesity Research and Education, Monash University, Alfred Hospital, Melbourne, Australia
    Obes Surg 16:1278-86. 2006
    ..The ability for aminotransferase levels to track histological features of non-alcoholic fatty liver disease (NAFLD) with weight loss has not been examined...
  15. doi request reprint Adjustable gastric banding and conventional therapy for type 2 diabetes: a randomized controlled trial
    John B Dixon
    Centre for Obesity Research and Education, Monash University Medical School, The Alfred Hospital, Melbourne, Victoria, Australia
    JAMA 299:316-23. 2008
    ..Observational studies suggest that surgically induced loss of weight may be effective therapy for type 2 diabetes...
  16. doi request reprint Effects of gastric band adjustments on intraluminal pressure
    Paul Robert Burton
    Centre for Obesity Research and Education, Monash University, Melbourne, Australia
    Obes Surg 19:1508-14. 2009
    ..Changes in intraluminal pressure may be important and explain patients reporting a tighter LAGB after saline is removed and an identical volume replaced...
  17. ncbi request reprint Laparoscopic adjustable gastric banding induces prolonged satiety: a randomized blind crossover study
    Andrew F R Dixon
    Centre for Obesity Research and Education, Monash University, Alfred Hospital, Prahran 3181, Vic, Australia
    J Clin Endocrinol Metab 90:813-9. 2005
    ..Identifying the mechanisms underlying LAGB-induced satiety may assist the understanding of human energy homeostasis and obesity...
  18. doi request reprint Changes in satiety, supra- and infraband transit, and gastric emptying following laparoscopic adjustable gastric banding: a prospective follow-up study
    Paul Robert Burton
    Centre for Obesity Research and Education CORE, Monash University, The Alfred Hospital, Melbourne, Vic, Australia
    Obes Surg 21:217-23. 2011
    ..How transit and gastric emptying change following LAGB and correlate with satiety and weight loss have not been adequately defined...
  19. ncbi request reprint Depression in association with severe obesity: changes with weight loss
    John B Dixon
    Department of Surgery, Monash University, Alfred Hospital, Melbourne, Victoria, Australia
    Arch Intern Med 163:2058-65. 2003
    ..The relationship between depression and severe obesity is unclear. We examined depression before and after surgically induced weight loss...
  20. doi request reprint Hunger control and regular physical activity facilitate weight loss after laparoscopic adjustable gastric banding
    Susan L Colles
    Centre for Obesity Research and Education, Alfred Hospital, Monash University, Melbourne, Victoria, 3181, Australia
    Obes Surg 18:833-40. 2008
    ..This study aimed to assess the extent and nature of change in energy intake and physical activity and identify factors associated with percentage weight loss (%WL) 12 months after laparoscopic adjustable gastric banding (LAGB)...
  21. ncbi request reprint Obesity and the white blood cell count: changes with sustained weight loss
    John B Dixon
    Australian Centre for Obesity Research and Education, Monash Medical School, The Alfred Hospital, Melbourne, Victoria, Australia
    Obes Surg 16:251-7. 2006
    ..The authors explored the relationship between the WBC and degree of obesity, basic anthropometry, and clinical and biochemical markers of the metabolic syndrome at baseline, and with weight loss following Lap-Band surgery...
  22. ncbi request reprint Alcohol consumption in the severely obese: relationship with the metabolic syndrome
    John B Dixon
    Monash University Department of Surgery, Alfred Hospital, Melbourne, Victoria, Australia
    Obes Res 10:245-52. 2002
    ..The aim of this study was to examine the association between the clinical and biochemical features of the metabolic syndrome and quantity and type of alcohol intake in the severely obese...
  23. doi request reprint Systematic review of erosion after laparoscopic adjustable gastric banding
    Kristine Egberts
    Centre for Obesity Research and Education CORE, The Alfred Centre, Monash University Melbourne, Melbourne, Australia
    Obes Surg 21:1272-9. 2011
    ..The most common treatment described in the literature is removal of the eroded band with delayed replacement. Replacement of the band is associated with maintenance of weight loss...
  24. ncbi request reprint Obesity, weight loss and bariatric surgery
    Paul E O'Brien
    Centre for Obesity Research and Education, Monash Medical School, Monash University, The Alfred Hospital, Commercial Road, Melbourne, VIC 3004, Australia
    Med J Aust 183:310-4. 2005
    ..It is effective, relatively safe and minimally invasive. The blocks to broader application of bariatric surgery should be identified and resolved...
  25. doi request reprint Symmetrical pouch dilatation after laparoscopic adjustable gastric banding: incidence and management
    Wendy A Brown
    Centre for Obesity Research and Education, Monash University, Melbourne, Australia
    Obes Surg 18:1104-8. 2008
    ..Since popularization of the pars flaccida approach and improved anterior fixation, it is our impression that the problem of symmetrical dilatation of the proximal gastric pouch has become more important...
  26. doi request reprint Predicting outcomes of intermediate term complications and revisional surgery following laparoscopic adjustable gastric banding: utility of the CORE classification and Melbourne motility criteria
    Paul Robert Burton
    Centre for Obesity Research and Education, Monash University, The Alfred Hospital, Commercial Rd Prahran 3181, Melbourne, Australia
    Obes Surg 20:1516-23. 2010
    ..Stress barium and high resolution manometry are promising investigations, however, have not yet been established as clinically useful...
  27. ncbi request reprint Changes in comorbidities and improvements in quality of life after LAP-BAND placement
    John B Dixon
    Monash University, Department of Surgery and the Alfred Hospital, Commercial Road, 3181, Melbourne, Victoria, Australia
    Am J Surg 184:51S-54S. 2002
    ..These changes provide perhaps the most compelling data regarding the value of LAP-BAND surgery and underlie the great satisfaction experienced by patients...
  28. ncbi request reprint Lipid profile in the severely obese: changes with weight loss after lap-band surgery
    John B Dixon
    Department of Surgery, Monash University, Alfred Hospital, Melbourne 3181, Victoria, Australia
    Obes Res 10:903-10. 2002
    ..To characterize dyslipidemia before and after weight loss in the severely obese...
  29. ncbi request reprint Smaller hip circumference is associated with dyslipidemia and the metabolic syndrome in obese women
    John B Dixon
    Centre for Obesity Research and Education CORE, Monash University, Melbourne, Victoria, Australia
    Obes Surg 17:770-7. 2007
    ..The authors explored the relationship between body composition measures and features of the metabolic syndrome (MtS) in women aged between 20 and 50 years with class I obesity...
  30. ncbi request reprint Daytime sleepiness in the obese: not as simple as obstructive sleep apnea
    John B Dixon
    Centre for Obesity Research and Education, Alfred Hospital, Melbourne 3181, Australia
    Obesity (Silver Spring) 15:2504-11. 2007
    ..The objective was to look for clinical, anthropometric, biochemical, and polysomnographic predictors of excessive daytime sleepiness as measured by the Epworth Sleepiness Scale (ESS) in obese patients...
  31. ncbi request reprint A prospective randomized trial of placement of the laparoscopic adjustable gastric band: comparison of the perigastric and pars flaccida pathways
    Paul E O'Brien
    The Australian Centre for Obesity Research and Education, Monash University and The Avenue Hospital, Melbourne, Victoria 3004, Australia
    Obes Surg 15:820-6. 2005
    ..We have tested this hypothesis using a randomized controlled trial format...
  32. ncbi request reprint Changes in body composition with weight loss: obese subjects randomized to surgical and medical programs
    John B Dixon
    Centre for Obesity Research and Education, Monash Medical School, The Alfred Hospital, Melbourne, Victoria, Australia 3004
    Obesity (Silver Spring) 15:1187-98. 2007
    ..To assess changes in body composition with weight loss in obese subjects randomized to a laparoscopic adjustable gastric band surgical program or a medical program using a very-low-energy diet and orlistat...
  33. ncbi request reprint Laparoscopic adjustable gastric banding in the treatment of morbid obesity
    Paul E O'Brien
    Department of Surgery, Monash University, The Alfred Hospital, Melbourne 3181, Australia
    Arch Surg 138:376-82. 2003
  34. ncbi request reprint Selecting the optimal patient for LAP-BAND placement
    John B Dixon
    Monash University Department of Surgery and the Alfred Hospital, 3181, Melbourne, Victoria, Australia
    Am J Surg 184:17S-20S. 2002
    ..The superobese (BMI >50) achieved a lower %EWL at 1 year after LAP-BAND placement compared with those with BMI <50, but there were no differences at the 2-, 3-, and 4-year follow-ups...
  35. doi request reprint Does pregnancy increase the need for revisional surgery after laparoscopic adjustable gastric banding?
    Rebecca N Haward
    The Centre for Obesity Research and Education CORE, Monash University Medical School, The Alfred Hospital, Melbourne, Australia
    Obes Surg 21:1362-9. 2011
    ..It is not known if pregnancy increases the need for revisional procedures. We compare the incidence of revisions in two matched cohorts of LAGB patients, with or without subsequent pregnancy...
  36. doi request reprint Characterization of the improvement in depressive symptoms following bariatric surgery
    Melissa J Hayden
    Centre for Obesity Research and Education, Monash University, Victoria, Australia
    Obes Surg 21:328-35. 2011
    ..Given the potential similarity in obesity-related and depressive symptoms, it is uncertain whether all components of depression would improve equally with weight loss...
  37. doi request reprint Grazing and loss of control related to eating: two high-risk factors following bariatric surgery
    Susan L Colles
    Monash University, Centre for Obesity Research and Education CORE, Alfred Hospital, Melbourne, Victoria, Australia
    Obesity (Silver Spring) 16:615-22. 2008
    ..Gastric restrictive surgery induces a marked change in eating behavior. However, the relationship between preoperative and postoperative eating behavior and weight loss outcome has received limited attention...
  38. doi request reprint Mechanisms of bolus clearance in patients with laparoscopic adjustable gastric bands
    Paul Robert Burton
    Centre for Obesity Research and Education CORE, Monash Medical School, The Alfred Hospital, Commercial Rd, Prahran, 3181, Melbourne, Australia
    Obes Surg 20:1265-72. 2010
    ..The components of esophageal function important to success with laparoscopic adjustable gastric banding (LAGB) are not well understood. A pattern of delayed, however, successful bolus transit across the LAGB is observed...
  39. ncbi request reprint Laparoscopic adjustable gastric banding
    Wendy Brown
    The Centre for Obesity Research and Education, Monash University, Department of Surgery, The Alfred Hospital and The Centre for Bariatric Surgery, Melbourne, Victoria
    Aust Fam Physician 38:972-6. 2009
    ..The laparoscopic adjustable gastric band is a useful tool in the treatment of severe obesity. It is a safe and durably effective procedure, however, optimal results depend upon the patient participating in a process of lifelong care...
  40. doi request reprint Perceived discrimination and stigmatisation against severely obese women: age and weight loss make a difference
    Melissa J Hayden
    Centre for Obesity Research and Education, School of Public Health and Preventative Medicine, Monash University, Melbourne, Australia
    Obes Facts 3:7-14. 2010
    ..Patients' perceptions about weight-related stigma and discrimination were assessed in 2 groups of patients, obese and laparoscopic adjustable gastric banding (LAGB)...
  41. ncbi request reprint Weight loss and early and late complications--the international experience
    Paul E O'Brien
    Monash University Department of Surgery and the Alfred Hospital, Commercial Road, 3181, Melbourne, Victoria, Australia
    Am J Surg 184:42S-45S. 2002
    ..In our series, %EWL at 5 years and 6 years was 54% and 57%, respectively. The LAP-BAND is proving to be extremely safe, able to facilitate good weight loss, and able to maintain weight loss over time...
  42. ncbi request reprint Patient motivation for bariatric surgery: characteristics and impact on outcomes
    Marije Libeton
    Monash University Department of Surgery, Alfred Hospital, Melbourne 3181, Victoria, Australia
    Obes Surg 14:392-8. 2004
    ..Motivation for seeking obesity surgery has not been studied. The authors explored the patient's motivation for selecting surgery and examined for a relationship between primary motivating factors and weight outcomes...
  43. doi request reprint Does exercise improve weight loss after bariatric surgery? A systematic review
    Kristine Egberts
    Centre for Obesity Research and Education CORE, School of Public Health and Preventive Medicine, Monash University, Commercial Road, Melbourne, Australia
    Obes Surg 22:335-41. 2012
    ..Observational studies suggest that exercise is associated with greater weight loss following bariatric surgery. Randomised controlled trials are required to further examine this relationship...
  44. ncbi request reprint Surgical vs conventional therapy for weight loss treatment of obstructive sleep apnea: a randomized controlled trial
    John B Dixon
    Obesity Research Unit, Department of General Practice, Monash University, Melbourne, Victoria, Australia
    JAMA 308:1142-9. 2012
    ..Obstructive sleep apnea (OSA) is strongly related to obesity. Weight loss is recommended as part of the overall management plan for obese patients diagnosed with OSA...
  45. doi request reprint Raised CRP levels in obese patients: symptoms of depression have an independent positive association
    John B Dixon
    Centre for Obesity Research and Education, Monash University, Alfred Hospital, Melbourne, Victoria, Australia
    Obesity (Silver Spring) 16:2010-5. 2008
    ..Are the effects of depression and obesity related or do they influence CRP levels independently?..
  46. ncbi request reprint Birth outcomes in obese women after laparoscopic adjustable gastric banding
    John B Dixon
    Australian Centre for Obesity Research and Education, Monash Medical School, The Alfred Hospital, Melbourne, Victoria, Australia 3004
    Obstet Gynecol 106:965-72. 2005
    ..This prospective study sought to examine the outcomes of 79 consecutive first pregnancies (> 20 weeks of gestation) in women following laparoscopic adjustable gastric banding (LAGB) for severe obesity...
  47. ncbi request reprint Preoperative weight loss with a very-low-energy diet: quantitation of changes in liver and abdominal fat by serial imaging
    Susan L Colles
    Centre for Obesity Research and Education, Monash University, Melbourne, Australia
    Am J Clin Nutr 84:304-11. 2006
    ..Despite its growing popularity, a VLED in this setting has received little attention...
  48. doi request reprint Confirmatory factor analysis of the Beck Depression Inventory in obese individuals seeking surgery
    Melissa J Hayden
    Centre for Obesity Research and Education, Monash University, Victoria, Australia
    Obes Surg 20:432-9. 2010
    ..The Beck Depression Inventory (BDI) is frequently employed as measure of depression in studies of obesity. The aim of the study was to assess the factorial structure of the BDI in obese patients prior to bariatric surgery...
  49. ncbi request reprint Health outcomes of severely obese type 2 diabetic subjects 1 year after laparoscopic adjustable gastric banding
    John B Dixon
    Department of Surgery, Monash University, Alfred Hospital, Melbourne 3181, Victoria, Australia
    Diabetes Care 25:358-63. 2002
    ..To prospectively examine the effect of weight loss 1 year after laparoscopic adjustable gastric band surgery on a broad range of health outcomes in 50 diabetic subjects...
  50. doi request reprint Laparoscopic adjustable gastric banding and progression from impaired fasting glucose to diabetes
    John M Wentworth
    Centre for Obesity Research and Education CORE, Monash University at The Alfred Centre, 99 Commercial Road, Melbourne, Vic, 3004, Australia
    Diabetologia 57:463-8. 2014
    ..Obesity and dysglycaemia are major risk factors for type 2 diabetes. We determined if obese people undergoing laparoscopic adjustable gastric banding (LAGB) had a reduced risk of progressing from impaired fasting glucose (IFG) to diabetes...
  51. doi request reprint Increased Smad signaling and reduced MRF expression in skeletal muscle from obese subjects
    Rani Watts
    School of Exercise and Nutrition Sciences, Deakin University, Melbourne, Australia
    Obesity (Silver Spring) 21:525-8. 2013
    ....
  52. ncbi request reprint Obesity is a surgical disease: overview of obesity and bariatric surgery
    Paul E O'Brien
    The Centre for Obesity Research and Education CORE, Monash University Department of Surgery, Melbourne, Victoria, Australia
    ANZ J Surg 74:200-4. 2004
  53. doi request reprint Validity of the Beck Depression Inventory as a screening tool for a clinical mood disorder in bariatric surgery candidates
    Melissa J Hayden
    Centre for Obesity Research and Education CORE, The Alfred Centre, The Alfred Hospital, Monash University, Level 6, 99 Commercial Road, Melbourne, Victoria, 3004, Australia
    Obes Surg 22:1666-75. 2012
    ..This study aimed to investigate the validity and reliability of the BDI-IA and BDI-II in severely obese bariatric surgery candidates...
  54. ncbi request reprint Permeability of the silicone membrane in laparoscopic adjustable gastric bands has important clinical implications
    John B Dixon
    Australian Centre for Obesity Research and Education, Monash Medical School, The Alfred Hospital, Melbourne, Australia
    Obes Surg 15:624-9. 2005
    ..We observe a small reduction of the satiety-promoting effect with time. The characteristics and clinical relevance of volume change have not been adequately investigated...
  55. ncbi request reprint A rational approach to cholelithiasis in bariatric surgery: its application to the laparoscopically placed adjustable gastric band
    Paul E O'Brien
    Monash University Department of Surgery, The Alfred Hospital, Melbourne, Victoria
    Arch Surg 138:908-12. 2003
    ..We analyzed the outcomes of a noninterventionist policy on 1000 patients undergoing laparoscopic adjustable gastric banding...
  56. ncbi request reprint The extent of the problem of obesity
    Paul E O'Brien
    Monash University Department of Surgery and the Alfred Hospital, Commercial Road, 3181, Melbourne, Victoria, Australia
    Am J Surg 184:4S-8S. 2002
    ..The quality of life of the obese is markedly reduced, and the costs to health care systems are great. Preventive programs have yet to affect the rising prevalence. An effective solution is needed...
  57. pmc Pro-inflammatory CD11c+CD206+ adipose tissue macrophages are associated with insulin resistance in human obesity
    John M Wentworth
    Autoimmunity and Transplantation Division, Walter and Eliza Hall Institute of Medical Research, Victoria, Australia
    Diabetes 59:1648-56. 2010
    ..We aimed to characterize macrophage phenotype and function in human subcutaneous and omental adipose tissue in relation to insulin resistance in obesity...
  58. ncbi request reprint Lap-band: outcomes and results
    Paul E O'Brien
    Monash University, Department of Surgery, The Alfred Hospital, Melbourne, Victoria, Australia
    J Laparoendosc Adv Surg Tech A 13:265-70. 2003
    ..After 10 years of experience in treating more than 100000 patients with the Lap-Band, it is timely for us to review the outcomes...
  59. ncbi request reprint Predicting sleep apnea and excessive day sleepiness in the severely obese: indicators for polysomnography
    John B Dixon
    Monash University Department of Surgery, Alfred Hospital, Melbourne, Australia
    Chest 123:1134-41. 2003
    ..Selection of patients for OPS would be enhanced if we could better predict those likely to have clinically significant OSA...
  60. ncbi request reprint Pro-fibrotic polymorphisms predictive of advanced liver fibrosis in the severely obese
    John B Dixon
    Monash University Department of Surgery, Alfred Hospital, Melbourne, VIC 3181, Australia
    J Hepatol 39:967-71. 2003
    ..Genetic factors may also be important. We hypothesize that high angiotensinogen (AT) and transforming growth factor-beta1 (TGF-beta1) producing genotypes increase the risk of liver fibrosis in obese subjects with NAFLD...
  61. pmc Cost-effectiveness of surgically induced weight loss for the management of type 2 diabetes: modeled lifetime analysis
    Catherine L Keating
    1Centre for Obesity Research and Education, Monash University, Melbourne, Australia
    Diabetes Care 32:567-74. 2009
    ..To estimate the cost-effectiveness of surgically induced weight loss relative to conventional therapy for the management of recently diagnosed type 2 diabetes in class I/II obese patients...
  62. ncbi request reprint Bariatric surgery provides unparalleled metabolic benefits
    John B Dixon
    Centre for Obesity Research and Education, Monash University, The Alfred Hospital, Melbourne, Australia
    Obes Surg 17:193-4. 2007
  63. ncbi request reprint A prospective, randomized, controlled clinical trial of placement of the artificial bowel sphincter (Acticon Neosphincter) for the control of fecal incontinence
    Paul E O'Brien
    Department of Surgery, Monash University, The Alfred Hospital, Melbourne, Australia
    Dis Colon Rectum 47:1852-60. 2004
    ..We have performed a prospective, randomized, controlled trial to evaluate the effect of placement of an artificial bowel sphincter (Acticon Neosphincter) on continence and quality of life in a group of severely incontinent adults...
  64. ncbi request reprint Surgery as an effective early intervention for diabesity: why the reluctance?
    John B Dixon
    Centre for Obesity Research and Education, Monash University, Alfred Hospital, Melbourne 3181, Australia
    Diabetes Care 28:472-4. 2005
  65. ncbi request reprint Sweet eating is not a predictor of outcome after Lap-Band placement. Can we finally bury the myth?
    Steven M Hudson
    Monash University Department of Surgery, Alfred Hospital, Melbourne, Victoria 3181, Australia
    Obes Surg 12:789-94. 2002
    ..Preoperative and current sweet eating behavior was assessed in subjects who have had Lap-Band surgery, to find if this influenced weight outcomes...
  66. ncbi request reprint Minimal reporting requirements for weight loss: current methods not ideal
    John B Dixon
    Australian Centre for Obesity Research and Education, Monash Medical School, The Alfred Hospital, Melbourne, Victoria, Australia
    Obes Surg 15:1034-9. 2005
    ..Our aim is to compare methods of reporting weight loss in surgical and medical studies, and in addition look for a minimal reporting requirement that allows meaningful comparison...
  67. ncbi request reprint Cardiovascular benefit of light to moderate alcohol consumption
    Andrew F Dixon
    Monash University, Alfred Hospital, Melbourne, Victoria
    Aust Fam Physician 32:649-52. 2003
    ..With Australian levels of obesity and type 2 diabetes now reaching epidemic proportions, lifestyle factors that can reduce cardiovascular risk are of critical importance...
  68. ncbi request reprint Nonalcoholic fatty liver disease: Improvement in liver histological analysis with weight loss
    John B Dixon
    Monash University Department of Surgery, Alfred Hospital, University of Melbourne, Melbourne, Victoria, Australia
    Hepatology 39:1647-54. 2004
    ..In conclusion, weight loss after surgery provides major improvement or resolution of obesity and metabolic syndrome-associated abnormal liver histological features in severely obese subjects...
  69. ncbi request reprint Neck circumference a good predictor of raised insulin and free androgen index in obese premenopausal women: changes with weight loss
    John B Dixon
    Monash University Department of Surgery, Alfred Hospital, Melbourne, Victoria, Australia
    Clin Endocrinol (Oxf) 57:769-78. 2002
    ..In this study, we examined the association between clinical and biochemical features of these syndromes and assess changes with weight loss...
  70. ncbi request reprint Systematic review of medium-term weight loss after bariatric operations
    Paul E O'Brien
    The Centre for Obesity Research and Education, Monash University, Melbourne, Victoria, Australia
    Obes Surg 16:1032-40. 2006
    ..The authors studied the durability of weight loss after bariatric surgery based on a systematic review of the published literature...
  71. ncbi request reprint Preoxygenation is more effective in the 25 degrees head-up position than in the supine position in severely obese patients: a randomized controlled study
    Benjamin J Dixon
    Australian Center for Obesity Research and Education, Monash University, Alfred Hospital, Melbourne 3181, Victoria, Australia
    Anesthesiology 102:1110-5; discussion 5A. 2005
    ..The authors explored the hypothesis that preoxygenation in the 25 degrees head-up position allows a greater safety margin for induction of anesthesia than the supine position...
  72. ncbi request reprint Shoulder pain is a common problem following laparoscopic adjustable gastric band surgery
    John B Dixon
    Australian Centre for Obesity Research and Education, Monash Medical School, The Alfred Hospital, Melbourne, Australia
    Obes Surg 15:1111-7. 2005
    ..Shoulder-tip pain is commonly reported following laparoscopic adjustable gastric band (LAGB) placement. The incidence, nature and factors that may increase the risk of pain have not been explored...
  73. ncbi request reprint Body image: appearance orientation and evaluation in the severely obese. Changes with weight loss
    John B Dixon
    Monash University, Department of Surgery, Alfred Hospital, Melbourne 3181, Victoria, Australia
    Obes Surg 12:65-71. 2002
    ..We assessed the importance of appearance, presentation and self-evaluation of appearance before and after weight loss, in severely obese subjects (BMI > 35 kg/m2)...
  74. doi request reprint Identification and functional characterization of protein kinase A phosphorylation sites in the major lipolytic protein, adipose triglyceride lipase
    Joanne Pagnon
    Department of Physiology, Monash University, Clayton, 3800 Victoria, Australia
    Endocrinology 153:4278-89. 2012
    ..Our studies suggest that β-adrenergic activation can result in PKA-mediated phosphorylation of ATGL Ser(406), to moderately increase ATGL-mediated lipolysis...