Research Topics
| Pradeep J NathanSummaryAffiliation: Monash University Country: Australia Publications
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Publications
The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agentPradeep J Nathan
Behavioural Neuroscience Laboratory, Department of Physiology, Monash Center for Brain and Behaviour, Monash University, Australia
J Herb Pharmacother 6:21-30. 2006..Overall, L-theanine displays a neuropharmacology suggestive of a possible neuroprotective and cognitive enhancing agent and warrants further investigation in animals and humans...
Evidence for modulation of facial emotional processing bias during emotional expression decoding by serotonergic and noradrenergic antidepressants: an event-related potential (ERP) studyRebecca Kerestes
Behavioural Neuroscience Laboratory, School of Psychology, Psychiatry and Psychological Medicine, Monash University, Melbourne, Australia
Psychopharmacology (Berl) 202:621-34. 2009....- Differential effects of acute serotonin and dopamine depletion on prepulse inhibition and p50 suppression measures of sensorimotor and sensory gating in humansCollette Mann
Behavioural Neuroscience Laboratory, School of Psychology, Psychiatry and Psychological Medicine, Monash University, Melbourne, Vic, Australia
Neuropsychopharmacology 33:1653-66. 2008.... - Evidence for sex differences in the loudness dependence of the auditory evoked potential in humansJessica L Oliva
School of Psychology and Psychiatry, Monash University, Melbourne, Vic, Australia
Hum Psychopharmacol 26:172-6. 2011..Given the reported sex dichotomy in serotonin neurotransmission, this study examined if there are sex differences in the LDAEP... - The cognitive effects of modulating the glycine site of the NMDA receptor with high-dose glycine in healthy controlsColin Palmer
Behavioural Neuroscience Laboratory, School of Psychology, Psychiatry and Psychological Medicine, Monash University, Victoria, Australia
Hum Psychopharmacol 23:151-9. 2008.... - The loudness dependence auditory evoked potential is insensitive to acute changes in serotonergic and noradrenergic neurotransmissionJessica Oliva
School of Psychology and Psychiatry, Monash University, Melbourne, Vic, Australia
Hum Psychopharmacol 25:423-7. 2010..The current study examined the effects of noradrenergic modulation as well as serotonergic modulation on the LDAEP... - Direct evidence that acutely enhancing serotonin with the selective serotonin reuptake inhibitor citalopram modulates the loudness dependence of the auditory evoked potential (LDAEP) marker of central serotonin functionPradeep J Nathan
Behavioural Neuroscience Laboratory, Department of Physiology, Monash Centre for Brain and Behaviour, Monash University, Melbourne, Australia
Hum Psychopharmacol 21:47-52. 2006..Together the results provide further support for the validity of the LDAEP as a non-invasive in vivo measure of central serotonin function in humans... 
Oxytocin attenuates amygdala reactivity to fear in generalized social anxiety disorderIzelle Labuschagne
School of Psychology and Psychiatry, Monash University, Melbourne, Australia
Neuropsychopharmacology 35:2403-13. 2010....- Acute serotonin and dopamine depletion improves attentional control: findings from the stroop taskKirsty E Scholes
Behavioural Neuroscience Laboratory, Department of Physiology, Monash Centre for Brain and Behavior, Monash University, Melbourne, Vic, Australia
Neuropsychopharmacology 32:1600-10. 2007..These findings enhance our understanding of the neurochemical basis of attentional control and the possible cause of attentional control deficits in schizophrenia... - Molecular imaging of the dopaminergic system and its association with human cognitive functionVanessa L Cropley
Department of Physiology, Behavioural Neuroscience Laboratory, Monash Centre for Brain and Behaviour, Monash University, Victoria, Australia
Biol Psychiatry 59:898-907. 2006.... - Estrogen prevents 5-HT1A receptor-induced disruptions of prepulse inhibition in healthy womenAndrea Gogos
Behavioural Neuroscience Laboratory, Mental Health Research Institute of Victoria, Parkville, Vic, Australia
Neuropsychopharmacology 31:885-9. 2006..Estrogen treatment, administered in the appropriate experimental conditions, prevented PPI deficits induced by 5-HT(1A) receptor activation and may therefore also play a protective role in sensorimotor gating deficits in schizophrenia... - Muscarinic and nicotinic receptor modulation of object and spatial n-back working memory in humansAmity Green
Behavioural Neuroscience Laboratory, Department of Physiology, Monash Centre for Brain and Behaviour, PO Box 13F, Monash University, Melbourne, VIC 3800, Australia
Pharmacol Biochem Behav 81:575-84. 2005.... - Muscarinic and nicotinic receptors synergistically modulate working memory and attention in humansJulia R Ellis
Behavioural Neuroscience Laboratory, Department of Physiology, Monash Centre for Brain and Behaviour, Monash University, Melbourne Australia
Int J Neuropsychopharmacol 9:175-89. 2006.... - Combined D1/D2 receptor stimulation under conditions of dopamine depletion impairs spatial working memory performance in humansKathryn A Ellis
Brain Sciences Institute, Swinburne University of Technology, Melbourne, Australia
Psychopharmacology (Berl) 181:771-80. 2005.... - An examination of acute changes in serotonergic neurotransmission using the loudness dependence measure of auditory cortex evoked activity: effects of citalopram, escitalopram and sertralineValérie Guille
Biological Psychiatry Research Unit, Brain Sciences Institute, Swinburne University of Technology, Melbourne, Vic, Australia
Hum Psychopharmacol 23:231-41. 2008..The aim of this study was to assess the sensitivity of the LDAEP to acute augmentation in central serotonergic neurotransmission in humans... - Effects of selective and combined serotonin and dopamine depletion on the loudness dependence of the auditory evoked potential (LDAEP) in humansBarry V O'Neill
Biological Psychiatry Research Unit, Brain Sciences Institute, Swinburne University of Technology, Melbourne, Australia
Hum Psychopharmacol 23:301-12. 2008..Accordingly we further examined the effects of selective serotonin, dopamine and simultaneous serotonin and dopamine depletion on the LDAEP in healthy subjects... - Small effect of dopamine release and no effect of dopamine depletion on [18F]fallypride binding in healthy humansVanessa L Cropley
Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 0135, USA
Synapse 62:399-408. 2008..These findings indicate that [18F]fallypride is useful for measuring amphetamine-induced dopamine release, but may be unreliable for estimating tonic dopamine levels, in striatum and extrastriatal regions of healthy humans... - The loudness dependence of the auditory evoked potential (LDAEP) as an in vivo biomarker of central serotonergic function in humans: rationale, evaluation and review of findingsBarry V O'Neill
Biological Psychiatry Research Unit, Brain Sciences Institute, Swinburne University of Technology, Melbourne, Australia
Hum Psychopharmacol 23:355-70. 2008..Subsequently, this review was undertaken in an attempt to critically evaluate the potential role of the LDAEP as a marker of the central 5-HT function... - Pre- and post-synaptic dopamine imaging and its relation with frontostriatal cognitive function in Parkinson disease: PET studies with [11C]NNC 112 and [18F]FDOPAVanessa L Cropley
Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 0135, USA
Psychiatry Res 163:171-82. 2008..These results suggest that striatal dopamine denervation may contribute to some frontostriatal cognitive impairment in moderate stage PD... - L-tryptophan challenge and cognitive deficits in bipolar disorder: evidence for hyperserotonergic and hypodopaminergic mechanismsPradeep J Nathan
Neuropsychopharmacology 28:2212-3; author reply 2214-6. 2003 - Brain monoamines and early visual information-processing speedBen J Harrison
Neuropharmacology Laboratory, Brain Sciences Institute, Swinburne University of Technology Melbourne, Australia
Int J Neuropsychopharmacol 5:295-300. 2002..These findings suggest that monoamines, whilst implicated in various forms of cognition are not central to IT, which measures the efficiency of perceptual intake and information-processing speed... - The acute nootropic effects of Ginkgo biloba in healthy older human subjects: a preliminary investigationPradeep J Nathan
Neuropharmacology Laboratory, Brain Sciences Institute, Swinburne University of Technology, Australia
Hum Psychopharmacol 17:45-9. 2002..No acute effects of Ginkgo biloba were found for any of the memory tests examined. The findings suggest that 120 mg of Ginkgo biloba has no acute nootropic effects in healthy older humans... - Acute augmentation of serotonin suppresses cardiovascular responses to emotional valenceAndrew H Kemp
Neuropsychopharmacology Laboratory, Brain Sciences Institute, Swinburne University of Technology, Hawthorn, Victoria VIC 3122, Australia
Int J Neuropsychopharmacol 7:65-70. 2004..These results suggest that 5-HT may modulate the cardiovascular HR response to visual emotional stimuli and indicate that 5-HT may have a protective effect on the cardiovascular responses to emotional stimuli... - Simultaneous depletion of serotonin and catecholamines impairs sustained attention in healthy female subjects without affecting learning and memoryCathy Matrenza
Neuropsychopharmacology Laboratory, Brain Sciences Institute, Swinburne University of Technology, Melbourne, Australia
J Psychopharmacol 18:21-31. 2004..These findings suggest that simultaneously depleting the availability of brain serotonin and catecholamines in healthy female subjects selectively impairs sustained attention, without affecting other cognitive domains... - Is the loudness dependence of the auditory evoked potential a sensitive and selective in vivo marker of central serotonergic function?Pradeep J Nathan
Neuropsychopharmacology 30:1584-5; author reply 1586-7. 2005 - The acute effects of L-theanine in comparison with alprazolam on anticipatory anxiety in humansKristy Lu
Neuropsychopharmacology Laboratory, Brain Sciences Institute, Swinburne, University of Technology, Victoria, Australia
Hum Psychopharmacol 19:457-65. 2004..The findings suggest that while L-theanine may have some relaxing effects under resting conditions, neither L-theanine not alprazolam demonstrate any acute anxiolytic effects under conditions of increased anxiety in the AA model... - Augmentation of serotonin enhances pleasant and suppresses unpleasant cortical electrophysiological responses to visual emotional stimuli in humansAndrew H Kemp
Neuropsychopharmacology Laboratory, Brain Sciences Institute, Swinburne University of Technology, Hawthorn VIC 3122, Australia
Neuroimage 22:1084-96. 2004..The findings suggest a possible neurophysiological mechanism underlying antidepressant drug action on emotion... - Pindolol does not augment central serotonin function increases to citalopram in humans: an auditory evoked potential investigationRebecca Segrave
Brain Sciences Institute, Swinburne University of Technology, Melbourne, Australia
Pharmacol Biochem Behav 85:82-90. 2006..The findings may provide further support for why pindolol may not be an effective therapeutic strategy to augment serotonin function and antidepressant response... - First-episode psychosis after taking an extract of Hypericum perforatum (St John's Wort)Ken Shimizu
Hum Psychopharmacol 19:275-6. 2004 - Selective effects of acute serotonin and catecholamine depletion on memory in healthy womenBen J Harrison
Neuropsychopharmacology Laboratory, Brain Sciences Institute, Swinburne University of Technology, Melbourne Australia
J Psychopharmacol 18:32-40. 2004..This may shed light on the role of these neurotransmitters in disorders that are characterized by significant memory impairment... - Sex differences in the effect of acute tryptophan depletion on declarative episodic memory: a pooled analysis of nine studiesAnke Sambeth
Department of Neurocognition, Faculty of Psychology, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
Neurosci Biobehav Rev 31:516-29. 2007..The findings provide further support for a critical role of serotonin in declarative episodic memory... - Tyrosine depletion alters cortical and limbic blood flow but does not modulate spatial working memory performance or task-related blood flow in humansKathryn A Ellis
Brain Sciences Institute, Swinburne University of Technology, Melbourne, Australia
Hum Brain Mapp 28:1136-49. 2007..These findings question the capacity of TPD to consistently modulate dopamine function and SWM neural networks in humans... - Effects of serotonin and catecholamine depletion on interleukin-6 activation and mood in human volunteersBen J Harrison
Brain Sciences Institute, Swinburne University of Technology, Melbourne, Australia
Hum Psychopharmacol 17:293-7. 2002..These findings indicate that a transient disruption in global monoamine function does not stimulate a proinflammatory response of IL-6 in normal volunteers...