Daniel Thomas Malone

Summary

Affiliation: Monash University
Country: Australia

Publications

  1. doi request reprint Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9)-tetrahydrocannabinol in rats
    Daniel Thomas Malone
    Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Victoria, Australia
    Pharmacol Biochem Behav 93:91-6. 2009
  2. doi request reprint A two-hit model: behavioural investigation of the effect of combined neonatal MK-801 administration and isolation rearing in the rat
    Ann Li Lim
    Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic, Australia
    J Psychopharmacol 26:1252-64. 2012
  3. doi request reprint Effect of cannabidiol in a MK-801-rodent model of aspects of schizophrenia
    Anand Gururajan
    Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria, 3052, Australia
    Behav Brain Res 222:299-308. 2011
  4. doi request reprint Isolation rearing in rats: effect on expression of synaptic, myelin and GABA-related immunoreactivity and its utility for drug screening via the subchronic parenteral route
    Ann Li Lim
    Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Victoria, Australia
    Brain Res 1381:52-65. 2011
  5. doi request reprint Consequences of early life MK-801 administration: long-term behavioural effects and relevance to schizophrenia research
    Ann Li Lim
    Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville 3052, Victoria, Australia
    Behav Brain Res 227:276-86. 2012
  6. doi request reprint Effect of testing conditions on the propsychotic action of MK-801 on prepulse inhibition, social behaviour and locomotor activity
    Anand Gururajan
    Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, 3052, Victoria, Australia
    Physiol Behav 99:131-8. 2010
  7. ncbi request reprint The effect of Delta9-tetrahydrocannabinol on sensorimotor gating in socially isolated rats
    Daniel Thomas Malone
    Department of Pharmaceutical Biology and Pharmacology, Victorian College of Pharmacy, Monash University, Parkville 3052, Vic, Australia
    Behav Brain Res 166:101-9. 2006

Detail Information

Publications7

  1. doi request reprint Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9)-tetrahydrocannabinol in rats
    Daniel Thomas Malone
    Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Victoria, Australia
    Pharmacol Biochem Behav 93:91-6. 2009
    ..This data suggests that CBD can reverse social withdrawal induced by low dose THC, but the combination of high dose THC and CBD impairs social interaction, possibly by decreasing locomotor activity...
  2. doi request reprint A two-hit model: behavioural investigation of the effect of combined neonatal MK-801 administration and isolation rearing in the rat
    Ann Li Lim
    Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic, Australia
    J Psychopharmacol 26:1252-64. 2012
    ..The preliminary predictive validity shown with clozapine suggests this model may be useful for predicting the efficacy of putative antipsychotics...
  3. doi request reprint Effect of cannabidiol in a MK-801-rodent model of aspects of schizophrenia
    Anand Gururajan
    Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria, 3052, Australia
    Behav Brain Res 222:299-308. 2011
    ..Further behavioural studies would be required using a range of species, strains, animal models and testing paradigms to conclusively establish the antipsychotic potential of cannabidiol...
  4. doi request reprint Isolation rearing in rats: effect on expression of synaptic, myelin and GABA-related immunoreactivity and its utility for drug screening via the subchronic parenteral route
    Ann Li Lim
    Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Victoria, Australia
    Brain Res 1381:52-65. 2011
    ....
  5. doi request reprint Consequences of early life MK-801 administration: long-term behavioural effects and relevance to schizophrenia research
    Ann Li Lim
    Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville 3052, Victoria, Australia
    Behav Brain Res 227:276-86. 2012
    ..Although this method may be suitable to model some aspects of schizophrenia in rodents, there are unmet areas which need to be addressed, notably the characterisation of its predictive value...
  6. doi request reprint Effect of testing conditions on the propsychotic action of MK-801 on prepulse inhibition, social behaviour and locomotor activity
    Anand Gururajan
    Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, 3052, Victoria, Australia
    Physiol Behav 99:131-8. 2010
    ..Based on these results, the testing conditions appear to have a significant influence on the outcome of experiments aimed at observing the propsychotic action of MK-801...
  7. ncbi request reprint The effect of Delta9-tetrahydrocannabinol on sensorimotor gating in socially isolated rats
    Daniel Thomas Malone
    Department of Pharmaceutical Biology and Pharmacology, Victorian College of Pharmacy, Monash University, Parkville 3052, Vic, Australia
    Behav Brain Res 166:101-9. 2006
    ..The lack of effect of SR 141716 in either grouped or isolated rats suggests that normal endocannabinoid function is not critical in sensorimotor gating processes...