Paul T King

Summary

Affiliation: Monash University
Country: Australia

Publications

  1. pmc Role of arformoterol in the management of COPD
    Paul King
    Monash University Department of Medicine, Monash Medical Centre, Australia
    Int J Chron Obstruct Pulmon Dis 3:385-91. 2008
  2. doi Phenotypes of adult bronchiectasis: onset of productive cough in childhood and adulthood
    Paul T King
    Respiratory and Sleep Medicine, Monash Medical Centre Southern Health, Melbourne, Australia
    COPD 6:130-6. 2009
  3. ncbi Bactericidal activity of neutrophils with reduced oxidative burst from adults with bronchiectasis
    Paul King
    Monash University Department of Medicine, Monash Medical Centre, 246 Clayton Road, Clayton, Melbourne, 3168 Australia
    APMIS 117:133-9. 2009
  4. doi Effect of interferon gamma and CD40 ligation on intracellular monocyte survival of nontypeable Haemophilus influenzae
    Paul King
    Monash University Department of Medicine, Monash Medical Centre, Melbourne, Australia
    APMIS 116:1043-9. 2008
  5. ncbi Lung diffusing capacity in adult bronchiectasis: a longitudinal study
    Paul T King
    Department of Respiratory and Sleep Medicine, Monash Medical Centre, 246 Clayton Road, Clayton, Melbourne 3168, Australia
    Respir Care 55:1686-92. 2010
  6. pmc Systemic humoral immunity to non-typeable Haemophilus influenzae
    P T King
    Monash University Department of Medicine, Monash Medical Centre, Melbourne, Australia
    Clin Exp Immunol 153:376-84. 2008
  7. pmc Cytotoxic T lymphocyte and natural killer cell responses to non-typeable Haemophilus influenzae
    P T King
    Monash University Department of Medicine, and Department of Respiratory and Sleep Medicine, Monash Medical Centre, Melbourne, Victoria, Australia
    Clin Exp Immunol 152:542-51. 2008
  8. ncbi Is there a role for inhaled corticosteroids and macrolide therapy in bronchiectasis?
    Paul King
    Monash University, Department of Medicine, Monash Medical Centre, Melbourne, Victoria, Australia
    Drugs 67:965-74. 2007
  9. ncbi Microbiologic follow-up study in adult bronchiectasis
    Paul T King
    Department of Respiratory and Sleep Medicine, Monash Medical Centre, Clayton, Melbourne 3168, Australia
    Respir Med 101:1633-8. 2007
  10. ncbi Outcome in adult bronchiectasis
    Paul T King
    Department of Respiratory Medicine, Monash Medical Centre, 246 Clayton Rd, Clayton, Melbourne, Victoria, Australia
    COPD 2:27-34. 2005

Detail Information

Publications18

  1. pmc Role of arformoterol in the management of COPD
    Paul King
    Monash University Department of Medicine, Monash Medical Centre, Australia
    Int J Chron Obstruct Pulmon Dis 3:385-91. 2008
    ..It can only be given in nebulized form. Arformoterol can potentially be given with other inhaled medications...
  2. doi Phenotypes of adult bronchiectasis: onset of productive cough in childhood and adulthood
    Paul T King
    Respiratory and Sleep Medicine, Monash Medical Centre Southern Health, Melbourne, Australia
    COPD 6:130-6. 2009
    ..In conclusion there were a number of significant differences between the child onset and adult onset group that may reflect different phenotypes of bronchiectasis...
  3. ncbi Bactericidal activity of neutrophils with reduced oxidative burst from adults with bronchiectasis
    Paul King
    Monash University Department of Medicine, Monash Medical Centre, 246 Clayton Road, Clayton, Melbourne, 3168 Australia
    APMIS 117:133-9. 2009
    ..The addition of interferon-gamma enhanced oxidative burst in both groups. Abnormal neutrophil function in some subjects with bronchiectasis may account for their high rate of infection...
  4. doi Effect of interferon gamma and CD40 ligation on intracellular monocyte survival of nontypeable Haemophilus influenzae
    Paul King
    Monash University Department of Medicine, Monash Medical Centre, Melbourne, Australia
    APMIS 116:1043-9. 2008
    ..Killing of one strain of NTHi could be enhanced by the addition of interferon gamma and CD40 ligation in both control and bronchiectasis subjects. Other strains were more resistant...
  5. ncbi Lung diffusing capacity in adult bronchiectasis: a longitudinal study
    Paul T King
    Department of Respiratory and Sleep Medicine, Monash Medical Centre, 246 Clayton Road, Clayton, Melbourne 3168, Australia
    Respir Care 55:1686-92. 2010
    ..Interstitial lung disease is also a feature of bronchiectasis, but whether this is associated with a decline in lung diffusing capacity (measured as the diffusing capacity of the lung for carbon monoxide [D(LCO)]) is not well known...
  6. pmc Systemic humoral immunity to non-typeable Haemophilus influenzae
    P T King
    Monash University Department of Medicine, Monash Medical Centre, Melbourne, Australia
    Clin Exp Immunol 153:376-84. 2008
    ..These findings may explain why NTHi rarely causes systemic disease in patients with chronic respiratory mucosal infection and emphasize the potential importance of cellular immunity against this bacterium...
  7. pmc Cytotoxic T lymphocyte and natural killer cell responses to non-typeable Haemophilus influenzae
    P T King
    Monash University Department of Medicine, and Department of Respiratory and Sleep Medicine, Monash Medical Centre, Melbourne, Victoria, Australia
    Clin Exp Immunol 152:542-51. 2008
    ..influenzae stimulation were the CTL and NK cells. The results suggest that CTL and NK cell responses may be important in preventing disease from nontypeable H. influenzae infection...
  8. ncbi Is there a role for inhaled corticosteroids and macrolide therapy in bronchiectasis?
    Paul King
    Monash University, Department of Medicine, Monash Medical Centre, Melbourne, Victoria, Australia
    Drugs 67:965-74. 2007
    ..The evidence available suggests that both medications have a role in the management of bronchiectasis. More definitive trials of ICS and macrolides in bronchiectasis will clarify the likely benefit of these therapies...
  9. ncbi Microbiologic follow-up study in adult bronchiectasis
    Paul T King
    Department of Respiratory and Sleep Medicine, Monash Medical Centre, Clayton, Melbourne 3168, Australia
    Respir Med 101:1633-8. 2007
    ..aeruginosa had the most severe bronchiectasis. Many subjects with bronchiectasis are colonized with the same bacterium over an average follow-up of 5 years. Different pathogens are associated with different patterns of clinical disease...
  10. ncbi Outcome in adult bronchiectasis
    Paul T King
    Department of Respiratory Medicine, Monash Medical Centre, 246 Clayton Rd, Clayton, Melbourne, Victoria, Australia
    COPD 2:27-34. 2005
    ..This study showed in this group of predominantly female adult patients with bronchiectasis followed up for 8 years, patients had persistent symptoms and an excess loss in FEV1...
  11. ncbi Bronchiectasis
    P King
    Department of Respiratory and Sleep Medicine, Monash Medical Centre, Melbourne, Victoria, Australia
    Intern Med J 36:729-37. 2006
    ..There may be considerable overlap with other chronic airway diseases. Treatment regimens are still not well defined. Patients tend to have ongoing symptoms and decline in respiratory function despite treatment...
  12. pmc Assessing immune function in adult bronchiectasis
    P T King
    Monash University Department of Medicine, Monash Medical Centre, Melbourne, Australia
    Clin Exp Immunol 144:440-6. 2006
    ..The findings of low B cells, Th cells and oxidative burst in bronchiectasis are novel. The results emphasize the importance of immune function assessment for adult bronchiectasis...
  13. ncbi Characterisation of the onset and presenting clinical features of adult bronchiectasis
    Paul T King
    Department of Respiratory Medicine, Monash Medical Centre, Monash University, Melbourne, Australia
    Respir Med 100:2183-9. 2006
    ..Therefore a study was performed on a large cohort of adult patients presenting to Monash Medical Centre (MMC) to survey the course of their disease up to the time of diagnosis...
  14. pmc The pathophysiology of bronchiectasis
    Paul T King
    Department of Medicine, Monash University, Monash Medical Centre, Melbourne, Victoria, Australia
    Int J Chron Obstruct Pulmon Dis 4:411-9. 2009
    ..The bacterial flora appears to change with progression of disease...
  15. ncbi Adaptive immunity to nontypeable Haemophilus influenzae
    Paul T King
    Department of Respiratory Medicine, Monash Medical Centre, Monash University, Melbourne
    Am J Respir Crit Care Med 167:587-92. 2003
    ..Therefore, chronic infection with NTHi in bronchiectasis is associated with a change in adaptive immunity that may be important in the pathogenesis of bronchial infection...
  16. ncbi Lung T-cell responses to nontypeable Haemophilus influenzae in patients with chronic obstructive pulmonary disease
    Paul T King
    Monash University Department of Medicine, Monash Medical Centre, Melbourne, Australia
    J Allergy Clin Immunol 131:1314-21.e14. 2013
    ..The antigens that activate lung T cells have not been clearly defined. Nontypeable Haemophilus influenzae (NTHi) is the dominant bacterium isolated from the lungs of patients with COPD...
  17. pmc Chest pain and exacerbations of bronchiectasis
    Paul T King
    Department of Respiratory and Sleep Medicine, Monash Medical Centre, Melbourne, Victoria, Australia Monash University Department of Medicine, Monash Medical Centre, Melbourne, Victoria, Australia
    Int J Gen Med 5:1019-24. 2012
    ..This study was performed to describe the characteristics of chest pain in adult bronchiectasis and to define the relationship of this pain to exacerbations...
  18. ncbi Use of antibiotics in bronchiectasis
    Paul T King
    Department of Respiratory Sleep Medicine, Monash Medical Centre, Clayton, 246 Clayton Rd, Clayton, Melbourne 3168, Australia
    Rev Recent Clin Trials 7:24-30. 2012
    ..It should be emphasized that nearly all of the trials in the literature have only had small numbers of subjects. The data that is available describing the use of antibiotics in bronchiectasis can generally be regarded as preliminary...