Research Topics
Species | Jason GillSummaryAffiliation: Monash University Country: Australia Publications
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Detail Information
Publications
Generation of a complete thymic microenvironment by MTS24(+) thymic epithelial cellsJason Gill
Department of Pathology and Immunology, Monash University Medical School, Commercial Road, Prahran, Melbourne 3181, Australia
Nat Immunol 3:635-42. 2002..These cells contained epithelial progenitor cells that were competent and sufficient to fully reconstitute the complex thymic epithelial microenvironment that supported normal T cell development...
Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude miceGina Balciunaite
Pediatric Immunology, Department of Research and Clinical biological Sciences, and The Children s Hospital, University of Basel, Basel, Switzerland
Nat Immunol 3:1102-8. 2002..Wnt molecules therefore provide regulatory signals critical for thymic function...
Donor T-cell alloreactivity against host thymic epithelium limits T-cell development after bone marrow transplantationMathias M Hauri Hohl
Department of Clinical Biological Sciences, Laboratory of Pediatric Immunology, University of Basel Children s Hospital, Mattenstrasse 28, 4058 Basel, Switzerland
Blood 109:4080-8. 2007..Hence, strategies that protect TECs may be necessary to improve immune reconstitution following allogeneic bone marrow transplantation...
Thymic generation and regenerationJason Gill
Department of Pathology and Immunology, Monash University, Faculty of Medicine, Nursing and Health Sciences, Alfred Medical Research and Education Precinct, Prahran, Australia
Immunol Rev 195:28-50. 2003....
Thymic regeneration: teaching an old immune system new tricksStuart P Berzins
Section on Immunology and Immunogenetics, Joslin Diabetes Center, Brigham and Women s Hospital, Dept of Medicine, Harvard Medical School, 1 Joslin Place, Boston, MA 02215, USA
Trends Mol Med 8:469-76. 2002..In the future, thymic regeneration might become a feasible and potentially powerful approach to rejuvenating a depleted peripheral T-cell pool...
Cellular and molecular events during early thymus developmentGeorg Hollander
Pediatric Immunology, The Center for Biomedicine, Department of Clinical Biological Sciences, University of Basel, and The University Children s Hospital of Basel, Basel, Switzerland
Immunol Rev 209:28-46. 2006..This review highlights recent findings related to the genetic control of early thymus organogenesis and provides insight into the molecular basis by which lymphocyte precursors are attracted to the thymus...
Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularityMagali Irla
University of Geneva Medical School, CMU, 1 rue Michel Servet, CH 1211, Geneva, Switzerland
Immunity 29:451-63. 2008....
Thymic selection threshold defined by compartmentalization of Ras/MAPK signallingMark A Daniels
Laboratory of Transplantation Immunology and Nephrology, Department of Research, University Hospital Basel, Hebelstrasse 20, 4031 Basel, Switzerland
Nature 444:724-9. 2006....
Deletion of PKBalpha/Akt1 affects thymic developmentElisabeth Fayard
Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland
PLoS ONE 2:e992. 2007..Defects in single components of this pathway prevent thymocytes from progressing beyond early T cell developmental stages. Protein kinase B (PKB) is the main effector of the PI3K pathway...
