Peter J Fuller

Summary

Affiliation: Monash University
Country: Australia

Publications

  1. ncbi request reprint Cortisol resistance in the New World revisited
    Peter J Fuller
    Prince Henry s Institute of Medical Research, Clayton and Walter and Eliza Hall Institute, Parkville, Victoria, Australia
    Trends Endocrinol Metab 15:296-9. 2004
  2. ncbi request reprint Mechanisms of mineralocorticoid action
    Peter J Fuller
    Prince Henry s Institute of Medical Research, Clayton, Victoria, Australia
    Hypertension 46:1227-35. 2005
  3. ncbi request reprint Seladin-1/DHCR24 expression in normal ovary, ovarian epithelial and granulosa tumours
    Peter J Fuller
    Prince Henry s Institute of Medical Research, Department of Gynaecology Oncology, Monash Medical Centre, Clayton, Victoria 3168, Australia
    Clin Endocrinol (Oxf) 63:111-5. 2005
  4. ncbi request reprint Aldosterone and DNA: the 50th anniversary
    Peter J Fuller
    Prince Henry s Institute of Medical Research, Clayton, Victoria 3168, Australia
    Trends Endocrinol Metab 15:143-6. 2004
  5. ncbi request reprint Signalling pathways in the molecular pathogenesis of ovarian granulosa cell tumours
    Peter J Fuller
    Prince Henry s Institute of Medical Research, PO Box 5152 Clayton, VIC 3168, Australia
    Trends Endocrinol Metab 15:122-8. 2004
  6. pmc Structural and functional characterization of the interdomain interaction in the mineralocorticoid receptor
    Jyotsna B Pippal
    Prince Henry s Institute of Medical Research, P O Box 5152, Clayton 3168, Victoria, Australia
    Mol Endocrinol 23:1360-70. 2009
  7. doi request reprint Deletion of mineralocorticoid receptors from macrophages protects against deoxycorticosterone/salt-induced cardiac fibrosis and increased blood pressure
    Amanda J Rickard
    Prince Henry s Institute of Medical Research, Clayton 3168, Australia
    Hypertension 54:537-43. 2009
  8. doi request reprint Mediators of mineralocorticoid receptor-induced profibrotic inflammatory responses in the heart
    Peter Wilson
    Prince Henry s Institute of Medical Research, P O Box 5152 Clayton, Melbourne, Vic, Australia
    Clin Sci (Lond) 116:731-9. 2009
  9. doi request reprint Colostrum supplementation restores insulin-like growth factor -1 levels and alters muscle morphology following massive small bowel resection
    Prue M Pereira-Fantini
    Intestinal Failure and Clinical Nutrition Group, Murdoch Childrens Research Institute, Atlantic Philanthropy Building, Flemington Road, Parkville 3052, Victoria, Australia
    JPEN J Parenter Enteral Nutr 32:266-75. 2008
  10. doi request reprint Activation of mineralocorticoid receptors by exogenous glucocorticoids and the development of cardiovascular inflammatory responses in adrenalectomized rats
    Morag J Young
    P O Box 5152, Clayton 3168, Victoria, Australia
    Endocrinology 151:2622-8. 2010

Collaborators

Detail Information

Publications62

  1. ncbi request reprint Cortisol resistance in the New World revisited
    Peter J Fuller
    Prince Henry s Institute of Medical Research, Clayton and Walter and Eliza Hall Institute, Parkville, Victoria, Australia
    Trends Endocrinol Metab 15:296-9. 2004
    ..We hypothesize that this region might be the site of interaction between the co-chaperones and the GR, and hence that the resistance occurs through the same mechanism, albeit from opposite sides...
  2. ncbi request reprint Mechanisms of mineralocorticoid action
    Peter J Fuller
    Prince Henry s Institute of Medical Research, Clayton, Victoria, Australia
    Hypertension 46:1227-35. 2005
    ..It is these nonepithelial actions of MR activation that need to be exploited for the development of antagonists that target the cardiovascular system while avoiding the undesirable side effects of renal MR blockade...
  3. ncbi request reprint Seladin-1/DHCR24 expression in normal ovary, ovarian epithelial and granulosa tumours
    Peter J Fuller
    Prince Henry s Institute of Medical Research, Department of Gynaecology Oncology, Monash Medical Centre, Clayton, Victoria 3168, Australia
    Clin Endocrinol (Oxf) 63:111-5. 2005
    ..Granulosa cell tumours of the ovary (GCT) as with adrenocortical adenomas arise from a steroidogenic tissue, respond to pituitary hormone stimulation and synthesize steroid hormones...
  4. ncbi request reprint Aldosterone and DNA: the 50th anniversary
    Peter J Fuller
    Prince Henry s Institute of Medical Research, Clayton, Victoria 3168, Australia
    Trends Endocrinol Metab 15:143-6. 2004
  5. ncbi request reprint Signalling pathways in the molecular pathogenesis of ovarian granulosa cell tumours
    Peter J Fuller
    Prince Henry s Institute of Medical Research, PO Box 5152 Clayton, VIC 3168, Australia
    Trends Endocrinol Metab 15:122-8. 2004
    ..The identification of these changes might lead not only to improved diagnosis, management and treatment of granulosa cell tumours, but could also offer new insights into normal granulosa cell biology...
  6. pmc Structural and functional characterization of the interdomain interaction in the mineralocorticoid receptor
    Jyotsna B Pippal
    Prince Henry s Institute of Medical Research, P O Box 5152, Clayton 3168, Victoria, Australia
    Mol Endocrinol 23:1360-70. 2009
    ....
  7. doi request reprint Deletion of mineralocorticoid receptors from macrophages protects against deoxycorticosterone/salt-induced cardiac fibrosis and increased blood pressure
    Amanda J Rickard
    Prince Henry s Institute of Medical Research, Clayton 3168, Australia
    Hypertension 54:537-43. 2009
    ....
  8. doi request reprint Mediators of mineralocorticoid receptor-induced profibrotic inflammatory responses in the heart
    Peter Wilson
    Prince Henry s Institute of Medical Research, P O Box 5152 Clayton, Melbourne, Vic, Australia
    Clin Sci (Lond) 116:731-9. 2009
    ....
  9. doi request reprint Colostrum supplementation restores insulin-like growth factor -1 levels and alters muscle morphology following massive small bowel resection
    Prue M Pereira-Fantini
    Intestinal Failure and Clinical Nutrition Group, Murdoch Childrens Research Institute, Atlantic Philanthropy Building, Flemington Road, Parkville 3052, Victoria, Australia
    JPEN J Parenter Enteral Nutr 32:266-75. 2008
    ....
  10. doi request reprint Activation of mineralocorticoid receptors by exogenous glucocorticoids and the development of cardiovascular inflammatory responses in adrenalectomized rats
    Morag J Young
    P O Box 5152, Clayton 3168, Victoria, Australia
    Endocrinology 151:2622-8. 2010
    ....
  11. ncbi request reprint Differences in the determinants of eplerenone, spironolactone and aldosterone binding to the mineralocorticoid receptor
    Fraser M Rogerson
    Prince Henry s Institute of Medical Research, Clayton, Victoria, Australia
    Clin Exp Pharmacol Physiol 31:704-9. 2004
    ....
  12. ncbi request reprint Does glucocorticoid receptor blockade exacerbate tissue damage after mineralocorticoid/salt administration?
    Amanda J Rickard
    Prince Henry s Institute of Medical Research, Clayton 3168, Australia
    Endocrinology 148:4829-35. 2007
    ....
  13. ncbi request reprint 17Beta-estradiol up-regulates vascular endothelial growth factor receptor-2 expression in human myometrial microvascular endothelial cells: role of estrogen receptor-alpha and -beta
    Caroline E Gargett
    Centre for Women s Health Research, Monash University Department of Obstetrics and Gynaecology, Monash Medical Centre, Clayton, Victoria 3168, Australia
    J Clin Endocrinol Metab 87:4341-9. 2002
    ..These observations suggest that 17beta-estradiol increases VEGFR-2 expression on human myometrial MEC promoting endothelial cell proliferation, an effect that varies between subjects and appears to be mediated primarily by ERalpha...
  14. doi request reprint Proteasome inhibition by bortezomib decreases proliferation and increases apoptosis in ovarian granulosa cell tumors
    Simon Chu
    Prince Henry s Institute of Medical Research, Victoria, Australia
    Reprod Sci 16:397-407. 2009
    ..This study suggests that advanced granulosa cell tumors, as represented by the cell lines, may respond to bortezomib either alone or in combination with other agents...
  15. doi request reprint Ovarian actions of estrogen receptor-β: an update
    Ann E Drummond
    Prince Henry s Institute of Medical Research, Clayton, Victoria, Australia
    Semin Reprod Med 30:32-8. 2012
    ..In this review, we examine the models that have been used to elucidate the roles ERβ plays in the ovary and consider the clinical consequences of altered ERβ expression or inappropriate activation of ERβ signaling...
  16. ncbi request reprint Expression status and mutational analysis of the ras and B-raf genes in ovarian granulosa cell and epithelial tumors
    Stacey Jamieson
    Prince Henry s Institute of Medical Research, Clayton, Victoria 3168, Australia
    Gynecol Oncol 95:603-9. 2004
    ..Furthermore, an apparent association has recently been reported between the presence of ras and B-raf mutations in the same cancer types. Activation of the ras/raf pathway would be predicted to be tumorigenic in granulosa cells...
  17. doi request reprint Nuclear receptor profiling of ovarian granulosa cell tumors
    Maria Alexiadis
    Prince Henry s Institute of Medical Research, Institute of Medical Research, Clayton, Victoria 3168, Australia
    Horm Cancer 2:157-69. 2011
    ..These findings provide a full profile of NR expression in GCT which will enable full characterization of their roles and potential as therapeutic targets...
  18. ncbi request reprint Molecular pathogenesis of granulosa cell tumours
    Peter J Fuller
    Prince Henry s Institute of Medical Research, PO Box 5152, Clayton, VIC 3168, Australia
    Mol Cell Endocrinol 191:89-96. 2002
    ..These observations provide a basis for future studies of GCT, including further characterisation of signalling pathways known to be important in the regulation of granulosa cell growth and differentiation...
  19. doi request reprint Liver receptor homologue-1 expression in ovarian epithelial and granulosa cell tumours
    Ashwini L Chand
    Prince Henry s Institute, PO Box 5152, Clayton, Victoria, Australia
    Steroids 78:700-6. 2013
    ..Its role in this disease therefore warrants further investigation...
  20. doi request reprint Characterization of the zebrafish (Danio rerio) mineralocorticoid receptor
    Jyotsna B Pippal
    Prince Henry s Institute of Medical Research, Monash University, Clayton, VIC 3168, Australia
    Mol Cell Endocrinol 332:58-66. 2011
    ..Conservation of the N/C-interaction between evolutionarily distant MR provides evidence of functional significance...
  21. doi request reprint Identification of ligand-selective peptide antagonists of the mineralocorticoid receptor using phage display
    Jun Yang
    Prince Henry s Institute of Medical Research, Clayton, Victoria 3168, Australia
    Mol Endocrinol 25:32-43. 2011
    ..This represents a novel mechanism of MR antagonism that may be manipulated in the rational design of a ligand- or tissue-selective MR modulator to treat diseases like heart failure without side effects such as hyperkalemia...
  22. ncbi request reprint Expression, mutational analysis and in vitro response of imatinib mesylate and nilotinib target genes in ovarian granulosa cell tumors
    Simon Chu
    Prince Henry s Institute of Medical Research, Clayton, Victoria, Australia
    Gynecol Oncol 108:182-90. 2008
    ..A recent case report of a patient with advanced recurrent GCT responding to the tyrosine kinase inhibitor, imatinib mesylate prompted us to explore a role for these therapies in GCT...
  23. ncbi request reprint Mineralocorticoid receptor binding, structure and function
    Fraser M Rogerson
    Prince Henry s Institute of Medical Research, P O Box 5152, Clayton, Victoria 3168, Australia
    Mol Cell Endocrinol 217:203-12. 2004
    ..These studies have been extended to an analysis of the interactions between the N-terminal and ligand-binding domains of the MR. In the last decade, AIP have been identified; the regulation of the genes encoding these AIP are discussed...
  24. doi request reprint Proteomic analysis of the intestinal adaptation response reveals altered expression of fatty acid binding proteins following massive small bowel resection
    Andrew N Stephens
    Prince Henry s Institute of Medical Research, Monash Medical Centre, Clayton, Victoria, Australia
    J Proteome Res 9:1437-49. 2010
    ..The observed FABP expression changes in the ileal epithelium occur as part of the intestinal adaptation response and could provide a clinically useful marker to evaluate adaptation following MSBR...
  25. ncbi request reprint A critical region in the mineralocorticoid receptor for aldosterone binding and activation by cortisol: evidence for a common mechanism governing ligand binding specificity in steroid hormone receptors
    Fraser M Rogerson
    Prince Henry s Institute of Medical Research, P O Box 5152, Clayton 3168, Victoria, Australia
    Mol Endocrinol 21:817-28. 2007
    ....
  26. doi request reprint Interactions of the mineralocorticoid receptor--within and without
    Jun Yang
    Department of Medicine, Prince Henry s Institute of Medical Research, Monash University, Clayton, Victoria 3168, Australia
    Mol Cell Endocrinol 350:196-205. 2012
    ..This review will discuss the current understanding of interactions involving the MR and highlight their relevance to ligand- or tissue-specificity as well as their suitability as therapeutic targets...
  27. doi request reprint The FOXL2 C134W mutation is characteristic of adult granulosa cell tumors of the ovary
    Stacey Jamieson
    Prince Henry s Institute of Medical Research, Clayton, Victoria, Australia
    Mod Pathol 23:1477-85. 2010
    ..This unique FOXL2 mutation appears to be characteristic of adult granulosa cell tumors...
  28. ncbi request reprint A direct effect of aldosterone on endothelin-1 gene expression in vivo
    Stephen Wong
    Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia
    Endocrinology 148:1511-7. 2007
    ..5-fold after 1 h in the kidney and colon, respectively. These results suggest that ET-1 is a direct aldosterone gene target in the kidney and colon and may play an important role in aldosterone-regulated ion homeostasis...
  29. doi request reprint Expression status and mutational analysis of the PTEN and P13K subunit genes in ovarian granulosa cell tumors
    Sophie Bittinger
    Prince Henry s Institute of Medical Research, Victoria, Australia
    Int J Gynecol Cancer 19:339-42. 2009
    ..These findings suggest that activation of PI3K signaling through PI3K/PTEN mutation or altered expression, in contrast to many other types of solid tumor, is not associated with GCT...
  30. ncbi request reprint Mammalian K-ras2 is a corticosteroid-induced gene in vivo
    Francine E Brennan
    Prince Henry s Institute of Medical Research, Clayton, Victoria 3168, Australia
    Endocrinology 147:2809-16. 2006
    ..In contrast to the documented up-regulation in the amphibian kidney, we did not observe regulation by corticosteroids in the kidney. However, regulation in a subpopulation of cells cannot be excluded...
  31. ncbi request reprint Transrepression of estrogen receptor beta signaling by nuclear factor-kappab in ovarian granulosa cells
    Simon Chu
    Prince Henry s Institute of Medical Research, P O Box 5152, Clayton, Victoria 3168, Australia
    Mol Endocrinol 18:1919-28. 2004
    ..Recent evidence suggests that ERbeta may function to promote differentiation. The inhibition of ERbeta in combination with the antiapoptotic properties of NF-kappaB may therefore contribute to pathogenesis of GCT...
  32. ncbi request reprint Expression of steroid receptor coactivators in cultured cells from paired myometrial and fibroid tissues
    Sonay Hussein-Fikret
    Prince Henry s Institute of Medical Research and Monash University Department of MedicineClayton, Victoria, Australia
    J Soc Gynecol Investig 12:445-51. 2005
    ....
  33. ncbi request reprint Dissecting mineralocorticoid receptor structure and function
    Fraser M Rogerson
    Prince Henry s Institute of Medical Research, P O Box 5152, Clayton, Victoria 3168, Australia
    J Steroid Biochem Mol Biol 85:389-96. 2003
    ..These studies provide insights into the molecular pathways that mediate aldosterone-induced amiloride-sensitive epithelial sodium transport...
  34. ncbi request reprint The role of the glucocorticoid receptor in mineralocorticoid/salt-mediated cardiac fibrosis
    Amanda J Rickard
    Dr Prince Henry s Institute of Medical Research, Endocrine Genetics, P O Box 5152, Clayton, Victoria 3168, Australia
    Endocrinology 147:5901-6. 2006
    ..Thus, blocking agonist activity at the GR neither enhances nor attenuates the fibrotic response, although it may modulate systolic blood pressure and macrophage recruitment in the mineralocorticoid/salt model...
  35. doi request reprint The importance of ERbeta signalling in the ovary
    Ann E Drummond
    Prince Henry s Institute of Medical Research, Victoria, Australia
    J Endocrinol 205:15-23. 2010
    ..It remains to be established as to what genes are regulated by ERbeta in the ovary. Finally, ERbeta has been shown to be regulated by gonadotrophins, the pituitary hormones mediating ovarian function...
  36. pmc Aromatase is a direct target of FOXL2: C134W in granulosa cell tumors via a single highly conserved binding site in the ovarian specific promoter
    Nicholas I Fleming
    Prince Henry s Institute of Medical Research, Clayton, Victoria, Australia
    PLoS ONE 5:e14389. 2010
    ..Recently, it has been reported that FOXL2 forms a complex with steroidogenic factor 1 (SF-1) which is a known regulator of aromatase in granulosa cells...
  37. ncbi request reprint Betaglycan alters NFκB-TGFβ2 cross talk to reduce survival of human granulosa tumor cells
    Maree Bilandzic
    Prince Henry s Institute, Department of Developmental Biology and Anatomy, Monash University, Clayton, Victoria 3168, Australia
    Mol Endocrinol 27:466-79. 2013
    ..Furthermore, our data suggest that loss of betaglycan during tumor progression in GCT alters the functional outcomes generated by NFκB and TGFβ pathway cross talk...
  38. doi request reprint Activin and inhibin, estrogens and NFκB, play roles in ovarian tumourigenesis is there crosstalk?
    Ann E Drummond
    Prince Henry s Institute of Medical Research, PO Box 5152, Clayton, Victoria 3168, Australia
    Mol Cell Endocrinol 359:85-91. 2012
    ..In this review we will highlight the roles that inhibin/activin, estrogen and NFκB, have been attributed within carcinogenesis and examine the potential for crosstalk between these pathways in ovarian cancer pathogenesis...
  39. doi request reprint Mechanisms of ligand specificity of the mineralocorticoid receptor
    Peter J Fuller
    Prince Henry s Institute and the Monash University, Department of Medicine, Clayton, Victoria 3168, Australia
    J Endocrinol 213:15-24. 2012
    ..The successful identification of ligand-specific interactions of the MR may provide the basis for the development of novel MR ligands with tissue specificity...
  40. pmc Purification and characterization of recombinant human mineralocorticoid receptor
    Colin D Clyne
    Prince Henry s Institute of Medical Research, Clayton, Melbourne, Victoria 3168, Australia
    Mol Cell Endocrinol 302:81-5. 2009
    ....
  41. ncbi request reprint Interdomain interactions in the mineralocorticoid receptor
    Fraser M Rogerson
    Prince Henry s Institute of Medical Research, P O Box 5152, Clayton, VIC 3168, Australia
    Mol Cell Endocrinol 200:45-55. 2003
    ..Interestingly, cortisol produces a much weaker N/C-interaction than aldosterone, and it is possible that the N/C-interaction may contribute to observed functional differences in the MR bound to the two ligands...
  42. doi request reprint 6th International Symposium on Aldosterone and ENaC: from gene to disease. 3-7 October 2007, Zermatt, Switzerland
    Peter J Fuller
    Prince Henry s Institute of Medical Research, P O Box 5152, Clayton, Victoria 3168, Australia
    Expert Opin Ther Targets 12:377-82. 2008
    ..As such the pathways involved in sodium homeostasis are now well recognised as important therapeutic targets...
  43. ncbi request reprint Inhibin-activin receptor subunit gene expression in ovarian tumors
    Peter J Fuller
    Prince Henry s Institute of Medical Research and Monash University, Department of Obstetrics and Gynecology, Monash Medical Center, Clayton, Victoria 3168, Australia
    J Clin Endocrinol Metab 87:1395-401. 2002
    ..Expression of betaglycan and p120 in most GCT argues against the hypothesis, but does not exclude the possibility that low or absent expression of p120 might be significant in a subset of these tumors...
  44. ncbi request reprint International congress on hormonal steroids and hormones in cancer
    Peter J Fuller
    Prince Henry s Institute of Medical Research, P O Box 5152, Clayton Victoria 3168, Australia
    Expert Opin Investig Drugs 12:293-6. 2003
  45. ncbi request reprint PRMT2 and RORγ Expression Are Associated With Breast Cancer Survival Outcomes
    Tae Gyu Oh
    Institute for Molecular Bioscience T G O, P B, J G, N E, S G, D H D, G E O M and School of Biomedical Science A G S, The University of Queensland, Brisbane, Queensland 4072, Australia Institute of Health and Biomedical Innovation E D, Queensland University of Technology, Translational Research Institute, Brisbane, Queensland 4102, Australia Prince Henry s Institute of Medical Research J W F, P J F, E R S, Clayton, Victoria 3168, Australia Dame Roma Mitchell Cancer Research Laboratory W D T, School of Medicine, The University of Adelaide, Adelaide 5005, South Australia, Australia Western Australian Institute for Medical Research P J L, University of Western Australia, Perth, Western Australia 6009, Australia Westmead Millennium Institute C L C, Sydney Medical School, Westmead, University of Sydney, New South Wales 2006, Australia and Department of Molecular and Clinical Medicine Wallenberg Laboratory G E O M, University of Gothenburg, S 405 30 Gothenburg, Sweden
    Mol Endocrinol 28:1166-85. 2014
    ..This study demonstrates the role and significant correlation between a histone methyltransferase (PRMT2)-dependent signature, RORγ, the cell-cycle regulation, DNA repair circuits, and breast cancer survival outcomes. ..
  46. ncbi request reprint Characterization of the inhibitor of kappaB kinase (IKK) complex in granulosa cell tumors of the ovary and granulosa cell tumor-derived cell lines
    Stacey Jamieson
    Steroid Receptor Biology Laboratory, Prince Henry s Institute of Medical Research, Melbourne, Vic, 3168, Australia
    Horm Cancer 4:277-92. 2013
    ..This study highlights unresolved issues in understanding the pathogenesis of GCT and in the use of the COV434 and KGN cells lines as model systems. ..
  47. doi request reprint High-temperature requirement factor A3 (Htra3): a novel serine protease and its potential role in ovarian function and ovarian cancers
    Marissa A Bowden
    Prince Henry s Institute of Medical Research, Clayton, Victoria, Australia
    Mol Cell Endocrinol 327:13-8. 2010
    ..The role of the PDZ domain, specific to the long form Htra3, and the specific substrates of Htra3 in vivo, need to be defined to better understand the roles of HtrA3 in the normal and malignant ovary...
  48. doi request reprint Management of granulosa cell tumour of the ovary
    Stacey Jamieson
    Prince Henry s Institute of Medical Research and Department of Medicine, Monash University, Monash Medical Centre, Clayton, Victoria, Australia
    Curr Opin Oncol 20:560-4. 2008
    ..The purpose of this review is to provide the clinician with an update on recent research relevant to granulosa cell tumours...
  49. doi request reprint Structure-function relationships in the mineralocorticoid receptor
    Jyotsna B Pippal
    Steroid Receptor Biology Laboratory, Prince Henry s Institute of Medical Research, PO Box 5152, Clayton, Victoria 3168, Australia
    J Mol Endocrinol 41:405-13. 2008
    ..The structural and functional determinants of MR function are described and their significance is discussed...
  50. ncbi request reprint Pseudohypoaldosteronism: kidney, lungs and colon
    Peter J Fuller
    Prince Henry s Institute of Medical Research, Clayton, Victoria 3168, Australia
    Clin Endocrinol (Oxf) 56:571-2. 2002
  51. ncbi request reprint Mineralocorticoid receptor blockade but not steroid withdrawal reverses renal fibrosis in deoxycorticosterone/salt rats
    Emily Y M Lam
    Prince Henry s Institute of Medical Research, Endocrine Genetics, Clayton, Victoria 3168, Australia
    Endocrinology 147:3623-9. 2006
    ..We hypothesize that continuing tubular inflammation and fibrosis despite DOC withdrawal indicates that the renal tissue may reflect MR activation in the context of tissue damage...
  52. ncbi request reprint Nuclear receptor expression in human differentiated thyroid tumors
    Michael Mond
    1 Prince Henry s Institute of Medical Research, Clayton, Australia
    Thyroid 24:1000-11. 2014
    ....
  53. pmc HtrA3 Is Downregulated in Cancer Cell Lines and Significantly Reduced in Primary Serous and Granulosa Cell Ovarian Tumors
    Harmeet Singh
    Prince Henry s Institute of Medical Research, Clayton, Victoria 3168, Australia
    J Cancer 4:152-64. 2013
    ..HtrA3, but not HtrA1 or HtrA2, was decreased in primary ovarian serous cystadenocarcinoma and granulosa cell tumors. This study provides evidence that HtrA3 may be the most relevant HtrA associated with ovarian malignancy...
  54. ncbi request reprint Estrogen receptor-alpha and -beta expression in microvascular endothelial cells and smooth muscle cells of myometrium and leiomyoma
    Caroline E Gargett
    Centre for Women s Health Research, Monash University Department of Obstetrics and Gynaecology, Monash Medical Centre, Clayton, Victoria, Australia
    Mol Hum Reprod 8:770-5. 2002
    ..Since ERalpha and ERbeta mediate opposing transcriptional activities, any effect of estrogen on the growth and development of fibroids is likely to be complex and may involve both SMC and MEC...
  55. ncbi request reprint Gene expression in the adapting small bowel after massive small bowel resection
    Lyrissa Baksheev
    Prince Henry s Institute of Medical Research, PO Box 5152, Clayton 3168, Victoria, Australia
    J Gastroenterol 41:1041-52. 2006
    ..The time points were chosen to reflect changes in gene expression early on in the response, because these are the genes that alter to initiate and maximize the response observed during adaptation...
  56. doi request reprint Molecular pathogenesis of granulosa cell tumors of the ovary
    Stacey Jamieson
    Prince Henry s Institute of Medical Research and Department of Medicine, Monash University, Clayton 3168, Australia
    Endocr Rev 33:109-44. 2012
    ..In this review, we explore the implications of this finding and the most recent work characterizing molecular pathways of potential pathogenetic significance in GCT...
  57. ncbi request reprint 3rd PacRim Breast and Prostate Cancer Meeting. 31 October-4 November 2006, Fraser Island, Queensland, Australia
    Peter J Fuller
    Prince Henry s Institute of Medical Research, PO Box 5152, Clayton, Victoria 3168, Australia
    Expert Opin Investig Drugs 16:397-401. 2007
    ....
  58. ncbi request reprint GLP-2 administration results in increased proliferation but paradoxically an adverse outcome in a juvenile piglet model of short bowel syndrome
    Prue M Pereira-Fantini
    Intestinal Failure and Clinical Nutrition Group, Murdoch Children s Research Institute, Royal Children s Hospital, Flemington Road, Parkville, Victoria 3052, Australia
    J Pediatr Gastroenterol Nutr 46:20-8. 2008
    ..The objective of the present study was to examine the effect of glucagon-like peptide-2 (GLP-2) administration in a piglet, juvenile model of short bowel syndrome...
  59. doi request reprint Minireview: stem cells in endocrine research: more than just Dolly
    Peter J Fuller
    Prince Henry s Institute of Medical Research, P O Box 5152, Clayton, Victoria 3168, Australia
    Endocrinology 149:4301-2. 2008
  60. ncbi request reprint Endocrine disorders of sodium regulation. Role of adrenal steroids in genetic defects causing sodium loss or sodium retention
    Ursula Kuhnle
    Center for Child and Adolescent Health, München Gauting, Heidelberg, Germany
    Horm Res 61:68-83. 2004
    ..Further syndromes may exist which once identified will help to better understand the basic physiology of aldosterone action...
  61. ncbi request reprint International Union of Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors
    Nick Z Lu
    Molecular Endocrinology Group, Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Pharmacol Rev 58:782-97. 2006
  62. ncbi request reprint Sertoli-Leydig cell tumor of the ovary, a rare cause of precocious puberty in a 12-month-old infant
    Catherine S Choong
    Department of Pediatric Endocrinology, Mater Misericordiae Hospitals, South Brisbane, Queensland 4104, Australia
    J Clin Endocrinol Metab 87:49-56. 2002
    ....