P B Fitzgerald

Summary

Affiliation: Monash University
Country: Australia

Publications

  1. ncbi request reprint A functional magnetic resonance imaging study of the effects of low frequency right prefrontal transcranial magnetic stimulation in depression
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Melbourne, Victoria, Australia
    J Clin Psychopharmacol 27:488-92. 2007
  2. ncbi request reprint A review of repetitive transcranial magnetic stimulation use in the treatment of schizophrenia
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology, Psychiatry and Psychological Medicine, Melbourne, Victoria, Australia
    Can J Psychiatry 53:567-76. 2008
  3. doi request reprint A randomized trial of unilateral and bilateral prefrontal cortex transcranial magnetic stimulation in treatment-resistant major depression
    P B Fitzgerald
    The Alfred and Monash University School of Psychology and Psychiatry, Melbourne, Victoria, Australia
    Psychol Med 41:1187-96. 2011
  4. ncbi request reprint Repetitive transcranial magnetic stimulation and electroconvulsive therapy: complementary or competitive therapeutic options in depression?
    Paul Fitzgerald
    Alfred Psychiatry Research Centre, Alfred and Monash University Department of Psychological Medicine, Vic, Australia
    Australas Psychiatry 12:234-8. 2004
  5. ncbi request reprint Victimization of patients with schizophrenia and related disorders
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred Hospital and Monash University Department of Psychological Medicine, Melbourne, Australia
    Aust N Z J Psychiatry 39:169-74. 2005
  6. ncbi request reprint An fMRI study of prefrontal brain activation during multiple tasks in patients with major depressive disorder
    Paul B Fitzgerald
    Department of Psychological Medicine, Alfred Psychiatry Research Centre, The Alfred and Monash University, Melbourne, Victoria, Australia
    Hum Brain Mapp 29:490-501. 2008
  7. pmc A meta-analytic study of changes in brain activation in depression
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Commercial Rd Melbourne, Victoria, Australia
    Hum Brain Mapp 29:683-95. 2008
  8. ncbi request reprint Motor cortical excitability and clinical response to rTMS in depression
    Paul B Fitzgerald
    Alfred Psychiatry Research Center, The Alfred and Monash University, Department of Psychological Medicine, Level 2, Old Baker Building, Commercial Road, Melbourne, VIC 3004, Australia
    J Affect Disord 82:71-6. 2004
  9. ncbi request reprint Reduced plastic brain responses in schizophrenia: a transcranial magnetic stimulation study
    Paul B Fitzgerald
    Department of Psychological Medicine, Alfred Psychiatry Research Centre, The Alfred and Monash University, Department of Psychological Medicine, Commercial Rd Melbourne, Victoria 3004, Australia
    Schizophr Res 71:17-26. 2004
  10. doi request reprint A study of the effectiveness of bilateral transcranial magnetic stimulation in the treatment of the negative symptoms of schizophrenia
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Melbourne, Victoria, Australia
    Brain Stimul 1:27-32. 2008

Detail Information

Publications89

  1. ncbi request reprint A functional magnetic resonance imaging study of the effects of low frequency right prefrontal transcranial magnetic stimulation in depression
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Melbourne, Victoria, Australia
    J Clin Psychopharmacol 27:488-92. 2007
    ..Response to LFR-TMS is associated with a bilateral reduction in frontal activation that does not seem to be a nonspecific effect of treatment and differs from the response to HFL-TMS...
  2. ncbi request reprint A review of repetitive transcranial magnetic stimulation use in the treatment of schizophrenia
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology, Psychiatry and Psychological Medicine, Melbourne, Victoria, Australia
    Can J Psychiatry 53:567-76. 2008
    ..These findings also highlight the pressing need for further research including multisite studies to confirm the value of these options...
  3. doi request reprint A randomized trial of unilateral and bilateral prefrontal cortex transcranial magnetic stimulation in treatment-resistant major depression
    P B Fitzgerald
    The Alfred and Monash University School of Psychology and Psychiatry, Melbourne, Victoria, Australia
    Psychol Med 41:1187-96. 2011
    ....
  4. ncbi request reprint Repetitive transcranial magnetic stimulation and electroconvulsive therapy: complementary or competitive therapeutic options in depression?
    Paul Fitzgerald
    Alfred Psychiatry Research Centre, Alfred and Monash University Department of Psychological Medicine, Vic, Australia
    Australas Psychiatry 12:234-8. 2004
    ..To examine issues pertaining to the potential clinical roles of repetitive transcranial magnetic stimulation (rTMS) and the relationship of these to the use of electroconvulsive therapy (ECT)...
  5. ncbi request reprint Victimization of patients with schizophrenia and related disorders
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred Hospital and Monash University Department of Psychological Medicine, Melbourne, Australia
    Aust N Z J Psychiatry 39:169-74. 2005
    ..We aimed to establish the 1-month prevalence of violent and non-violent victimization in a sample of patients with schizophrenia spectrum disorders and to investigate the determinants of victimization...
  6. ncbi request reprint An fMRI study of prefrontal brain activation during multiple tasks in patients with major depressive disorder
    Paul B Fitzgerald
    Department of Psychological Medicine, Alfred Psychiatry Research Centre, The Alfred and Monash University, Melbourne, Victoria, Australia
    Hum Brain Mapp 29:490-501. 2008
    ..We aimed to assess brain activation related to cognitive performance during planning and working memory tasks...
  7. pmc A meta-analytic study of changes in brain activation in depression
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Commercial Rd Melbourne, Victoria, Australia
    Hum Brain Mapp 29:683-95. 2008
    ..The aim of this study was to use a quantitative meta-analytic technique to synthesise the results of much of this research...
  8. ncbi request reprint Motor cortical excitability and clinical response to rTMS in depression
    Paul B Fitzgerald
    Alfred Psychiatry Research Center, The Alfred and Monash University, Department of Psychological Medicine, Level 2, Old Baker Building, Commercial Road, Melbourne, VIC 3004, Australia
    J Affect Disord 82:71-6. 2004
    ....
  9. ncbi request reprint Reduced plastic brain responses in schizophrenia: a transcranial magnetic stimulation study
    Paul B Fitzgerald
    Department of Psychological Medicine, Alfred Psychiatry Research Centre, The Alfred and Monash University, Department of Psychological Medicine, Commercial Rd Melbourne, Victoria 3004, Australia
    Schizophr Res 71:17-26. 2004
    ..We aimed to determine whether patients with schizophrenia would exhibit an abnormal response to repetitive TMS (rTMS) applied to the motor cortex and whether this would relate to deficient cortical inhibition...
  10. doi request reprint A study of the effectiveness of bilateral transcranial magnetic stimulation in the treatment of the negative symptoms of schizophrenia
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Melbourne, Victoria, Australia
    Brain Stimul 1:27-32. 2008
    ..The study therefore aimed to assess the efficacy of bilateral high-frequency rTMS in the treatment of negative symptoms...
  11. ncbi request reprint A double-blind sham-controlled trial of repetitive transcranial magnetic stimulation in the treatment of refractory auditory hallucinations
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Commercial Road, Melbourne, Victoria 3004, Australia
    J Clin Psychopharmacol 25:358-62. 2005
    ..We aimed to test this hypothesis in a randomized double-blind trial...
  12. ncbi request reprint A study of the effects of lorazepam and dextromethorphan on the response to cortical 1 Hz repetitive transcranial magnetic stimulation
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Commercial Road Melbourne, Victoria 3004, Australia
    Neuroreport 16:1525-8. 2005
    ..These results suggest that cortical responses to 1 Hz repetitive transcranial magnetic stimulation are dependent on activity at both gamma-aminobutyric acid and N-methyl-D-asparate receptor systems...
  13. ncbi request reprint A preliminary fMRI study of the effects on cortical activation of the treatment of refractory auditory hallucinations with rTMS
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Commercial Rd, Melbourne, Victoria 3004, Australia
    Psychiatry Res 155:83-8. 2007
    ..There was a significant increase and more normal task related brain activation in brain areas involved in language processing including left temporoparietal cortex after rTMS treatment...
  14. doi request reprint A transcranial magnetic stimulation study of the effects of cannabis use on motor cortical inhibition and excitability
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology, Psychiatry and Psychological Medicine, Commercial Rd Melbourne, Victoria, Australia
    Neuropsychopharmacology 34:2368-75. 2009
    ..Further research is required to explore whether this results from chronic cannabis use or reflects an underlying predisposition to developing chronic substance use problems...
  15. ncbi request reprint Naturalistic study of the use of transcranial magnetic stimulation in the treatment of depressive relapse
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, Department of Psychological Medicine, Monash University, Melbourne, Victoria, Australia
    Aust N Z J Psychiatry 40:764-8. 2006
    ..Little is known about the long-term impact of the treatment on the disorder and its effectiveness when applied for repeated relapses of depression over time...
  16. ncbi request reprint A comprehensive review of the effects of rTMS on motor cortical excitability and inhibition
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychiatry, Psychology and Psychological Medicine, Commercial Rd Melbourne, VIC 3004, Australia
    Clin Neurophysiol 117:2584-96. 2006
    ..Further research is required, however, before these paradigms can be more widely adopted...
  17. ncbi request reprint An analysis of functional neuroimaging studies of dorsolateral prefrontal cortical activity in depression
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University, Department of Psychological Medicine, Melbourne, Victoria 3004, Australia
    Psychiatry Res 148:33-45. 2006
    ..At this stage, the results of imaging studies published to date have limited capacity to inform the choice of optimal prefrontal cortical region for the use in rTMS treatment studies...
  18. ncbi request reprint The treatment of recurring auditory hallucinations in schizophrenia with rTMS
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Victoria, Australia
    World J Biol Psychiatry 7:119-22. 2006
    ..These studies have generally been positive, but treatment has only been provided for short periods of time and little is known about the longer-term impact of TMS on the course of hallucinations...
  19. doi request reprint A study of the effectiveness of high-frequency left prefrontal cortex transcranial magnetic stimulation in major depression in patients who have not responded to right-sided stimulation
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Commercial Road, Melbourne, Victoria 3004, Australia
    Psychiatry Res 169:12-5. 2009
    ..There appears to be a significant but modest likelihood of response to left-sided TMS in patients who fail right-sided stimulation, but there is no difference in efficacy between 5- and 10-Hz stimulation...
  20. doi request reprint A randomized trial of rTMS targeted with MRI based neuro-navigation in treatment-resistant depression
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology, Psychiatry and Psychological Medicine, Commercial Rd Melbourne, Victoria, Australia
    Neuropsychopharmacology 34:1255-62. 2009
    ..Further research is required to confirm this in larger samples, or to establish whether an alternate method based on surface anatomy, including measurement from motor cortex, can be substituted for the standard 5 cm method...
  21. ncbi request reprint A randomized, controlled trial of sequential bilateral repetitive transcranial magnetic stimulation for treatment-resistant depression
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Melbourne, Victoria, Australia
    Am J Psychiatry 163:88-94. 2006
    ..The authors evaluated sequentially combined high-frequency left-side rTMS and low-frequency rTMS to the right prefrontal cortex for treatment-resistant depression...
  22. ncbi request reprint A randomized trial of low-frequency right-prefrontal-cortex transcranial magnetic stimulation as augmentation in treatment-resistant major depression
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Melbourne, Victoria, Australia
    Int J Neuropsychopharmacol 9:655-66. 2006
    ..2-Hz right PFC rTMS has antidepressant properties but offers no advantage over 1 Hz despite doubling pulse number...
  23. doi request reprint Exploring the optimal site for the localization of dorsolateral prefrontal cortex in brain stimulation experiments
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology, Psychiatry and Psychological Medicine, Melbourne, Victoria, Australia
    Brain Stimul 2:234-7. 2009
    ..Dorsolateral prefrontal cortex (DLPFC) is a common target for repetitive transcranial magnetic stimulation (rTMS) experiments and therapeutic protocols...
  24. ncbi request reprint Transcranial magnetic stimulation in the treatment of depression: a double-blind, placebo-controlled trial
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred Hospital, and the Department of Psychological Medicine, Monash University, Australia
    Arch Gen Psychiatry 60:1002-8. 2003
    ..Low-frequency stimulation to the right prefrontal cortex (LFR-TMS) has also shown promise, although it has not been assessed in treatment-resistant depression and its effects have not been compared with those of HFL-TMS...
  25. ncbi request reprint Intensity-dependent effects of 1 Hz rTMS on human corticospinal excitability
    Paul B Fitzgerald
    Department of Psychological Medicine, Dandenong Psychiatry Research Centre, Monash University, P O Box 956, Victoria 3175, Australia
    Clin Neurophysiol 113:1136-41. 2002
    ..This study explored whether the effects of repetitive transcranial magnetic stimulation (rTMS) on corticospinal excitability are dependent on the stimulation intensity and examined the effect of rTMS on inhibitory function...
  26. doi request reprint GABA and cortical inhibition in motor and non-motor regions using combined TMS-EEG: a time analysis
    Paul B Fitzgerald
    Monash Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology, Psychiatry and Psychological Medicine, Melbourne, VIC 3004, Australia
    Clin Neurophysiol 120:1706-10. 2009
    ..This study aimed to further evaluate recent methods of the assessment of LICI in non motor regions with ppTMS and electroencephalography (EEG)...
  27. ncbi request reprint Depressive, positive, negative and parkinsonian symptomsin schizophrenia
    Paul B Fitzgerald
    Dandenong Psychiatry Research Centre, Monash University, Department of Psychosocial Medicine, Victoria 3175, Australia
    Aust N Z J Psychiatry 36:340-6. 2002
    ..The aim of this study was to investigate the relationship of depressive to positive, negative and parkinsonian symptoms using the recent adaptation of the Positive and Negative Syndrome Scale (PANSS)...
  28. ncbi request reprint The role of early warning symptoms in the detection and prevention of relapse in schizophrenia
    P B Fitzgerald
    Dandenong Psychiatry Research Centre, Monash University Department of Psychological Medicine, Victoria, Australia
    Aust N Z J Psychiatry 35:758-64. 2001
    ..The aim of this paper is to review the literature on the detection of relapse in schizophrenia and to draw conclusions that may be of use in the implementation of clinical programs...
  29. ncbi request reprint The application of transcranial magnetic stimulation in psychiatry and neurosciences research
    P B Fitzgerald
    Dandenong Psychiatry Research Centre, Department of Psychological Medicine, Monash University, PO Box 956, Dandenong, Victoria 3175, Australia
    Acta Psychiatr Scand 105:324-40. 2002
    ..The aim of this article is to review the application of TMS as an investigative tool and as a potential therapeutic modality in psychiatric disorders...
  30. doi request reprint The use of repetitive transcranial magnetic stimulation and vagal nerve stimulation in the treatment of depression
    Paul B Fitzgerald
    The Alfred and Monash University School of Psychology, Psychiatry and Psychological Medicine, Victoria, Australia
    Curr Opin Psychiatry 21:25-9. 2008
    ..The aim of this paper is to review recent therapeutic trials of these techniques...
  31. ncbi request reprint A transcranial magnetic stimulation study of inhibitory deficits in the motor cortex in patients with schizophrenia
    Paul B Fitzgerald
    Dandenong Psychiatric Research Centre, Monash University, Department of Psychological Medicine and Dandenong Area Mental Health Service, P O Box 956, Victoria, 3175, Dandenong, Australia
    Psychiatry Res 114:11-22. 2002
    ..These deficits appear to be of cortical origin. Their relationship to dysfunction in other cortical networks requires further elucidation...
  32. doi request reprint Priming stimulation enhances the effectiveness of low-frequency right prefrontal cortex transcranial magnetic stimulation in major depression
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Melbourne, Victoria, Australia
    J Clin Psychopharmacol 28:52-8. 2008
    ..The aim of this study was to investigate whether priming stimulation would enhance therapeutic response to low-frequency rTMS in patients with depression...
  33. ncbi request reprint A transcranial magnetic stimulation study of the effects of olanzapine and risperidone on motor cortical excitability in patients with schizophrenia
    Paul B Fitzgerald
    Dandenong Psychiatry Research Centre, Monash University School of Psychology, Psychiatry and Psychological Medicine, P O Box 956, Dandenong, Victoria 3175, Australia
    Psychopharmacology (Berl) 162:74-81. 2002
    ..Limited information is available as to how these neurotransmitters are affected by commonly prescribed antipsychotic agents...
  34. ncbi request reprint The relationship of changes in leptin, neuropeptide Y and reproductive hormones to antipsychotic induced weight gain
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, Monash University, Department of Psychological Medicine, Victoria, Australia
    Hum Psychopharmacol 18:551-7. 2003
    ..The aim was to investigate whether AP-induced weight gain was related to leptin and NPY abnormalities and whether these were associated with a disruption of gonadal steroid production...
  35. doi request reprint The effects of repetitive transcranial magnetic stimulation in the treatment of depression
    Paul B Fitzgerald
    Monash Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology and Psychiatry, First Floor Old Baker Building, Commercial Road Melbourne, 3004, Victoria 3181 Australia
    Expert Rev Med Devices 8:85-95. 2011
    ..Research is also required to evaluate the long-term effects of rTMS treatment, its use as a maintenance therapy and to establish reliable predictors of response to treatment...
  36. ncbi request reprint A longitudinal study of patient- and observer-rated quality of life in schizophrenia
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Melbourne, VIC 3004, Australia
    Psychiatry Res 119:55-62. 2003
    ..They should be considered as separate and complementary outcome variables and utilized accordingly...
  37. ncbi request reprint A transcranial magnetic stimulation study of abnormal cortical inhibition in schizophrenia
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Commercial Rd, Victoria 3004, Melbourne, Australia
    Psychiatry Res 118:197-207. 2003
    ..Increased I-wave facilitation suggests deficient function of cortical inhibitory GABAergic activity. This is consistent with previous research that has found deficient cortical inhibition in patients with schizophrenia...
  38. ncbi request reprint A comparative study of the effects of repetitive paired transcranial magnetic stimulation on motor cortical excitability
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychiatry, Psychology and Psychological Medicine, Commercial Road, Melbourne, Victoria 3004, Australia
    J Neurosci Methods 165:265-9. 2007
    ..We aimed to compare the post-train effects of 15 min trains of rppTMS to investigate the potential therapeutic application of this technique as well as to compare it to a standard high frequency repetitive TMS paradigm...
  39. ncbi request reprint Is it time to introduce repetitive transcranial magnetic stimulation into standard clinical practice for the treatment of depressive disorders?
    Paul Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Prahan, Victoria, Australia
    Aust N Z J Psychiatry 37:5-11; discussion 12-4. 2003
    ..To examine issues relating to the potential introduction of repetitive transcranial magnetic stimulation (rTMS) into clinical practice as a treatment for depression...
  40. ncbi request reprint Australian Schizophrenia Care and Assessment Programme: real-world schizophrenia: economics
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, Monash University School of Psychology, Psychiatry and Psychological Medicine, Alfred Hospital, Melbourne, Vic, Australia
    Aust N Z J Psychiatry 41:819-29. 2007
    ....
  41. ncbi request reprint Cortical inhibition in motor and non-motor regions: a combined TMS-EEG study
    Paul B Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology, Psychiatry and Psychological Medicine, Victoria, Australia
    Clin EEG Neurosci 39:112-7. 2008
    ..These data suggest that CI can be recorded by combining TMS with EEG and may facilitate future research attempting to ascertain the role of CI in the pathophysiology of several neurologic and psychiatric disorders...
  42. ncbi request reprint A confirmatory factor analytic evaluation of the pentagonal PANSS model
    Paul B Fitzgerald
    Dandenong Psychiatry Research Centre, Department of Psychological Medicine, Monash University, PO Box 956, 3175, Dandenong, Victoria, Australia
    Schizophr Res 61:97-104. 2003
    ..The use of the pentagonal model has similar difficulties as earlier models and more research is required to ascertain the optimal method for measuring symptom dimensions in research and clinical settings...
  43. ncbi request reprint Estrogen - a potential treatment for schizophrenia
    J Kulkarni
    Dandenong Psychiatry Research Centre, Monash University Department of Psychological Medicine, David St, Dandenong, Victoria 3175, Melbourne, Australia
    Schizophr Res 48:137-44. 2001
    ..The positive impact of estrogen treatment on psychotic symptoms by a direct effect on dopamine and serotonin systems or via an indirect prolactin-mediated effect may be very useful in the overall treatment of women with schizophrenia...
  44. ncbi request reprint Subject and observer-rated quality of life in schizophrenia
    P B Fitzgerald
    Dandenong Psychiatry Research Centre, Monash University and Dandenong Area Mental Health Service, Victoria, Australia
    Acta Psychiatr Scand 103:387-92. 2001
    ..CONCLUSION: Life satisfaction and objectively rated quality of life are not closely related and appear to have different determinants in patients with schizophrenia...
  45. doi request reprint Emotive interference during cognitive processing in major depression: an investigation of lower alpha 1 activity
    R A Segrave
    Monash Alfred Psychiatry Research Centre, The Alfred and Monash University Central Clinical School, Victoria, Australia
    J Affect Disord 141:185-93. 2012
    ..The current study investigated the electrophysiological correlates of competing cognitive and emotional processing demands in MDD...
  46. doi request reprint Upper alpha activity during working memory processing reflects abnormal inhibition in major depression
    R A Segrave
    Monash Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology and Psychiatry, Victoria, Australia
    J Affect Disord 127:191-8. 2010
    ..Moreover, it has been suggested that alpha activity reflects internally mediated inhibitory process and attenuated inhibition has been suggested to contribute to WM inefficacy...
  47. ncbi request reprint A study of transcallosal inhibition in schizophrenia using transcranial magnetic stimulation
    P B Fitzgerald
    Dandenong Psychiatry Research Centre, Monash University and Dandenong Area Mental Health Service, P O Box 956, Dandenong, VIC 3175, Australia
    Schizophr Res 56:199-209. 2002
    ..The latency of TCI is not altered in the patient group suggesting that cortical inhibitory mechanisms, rather than corpus callosal ones, are likely to be the cause of these TCI alterations...
  48. ncbi request reprint Negative symptoms: A review of schizophrenia, melancholic depression and Parkinson's disease
    C Winograd-Gurvich
    Experimental Neuropsychology Research Unit, Psychology Department, Monash University, Melbourne, Victoria 3800, Australia
    Brain Res Bull 70:312-21. 2006
    ....
  49. ncbi request reprint Self-paced saccades and saccades to oddball targets in Parkinson's disease
    C Winograd-Gurvich
    Experimental Neuropsychology Research Unit, School of Psychology, Psychiatry and Psychological Medicine, Monash University, Clayton, Victoria 3800, Australia
    Brain Res 1106:134-41. 2006
    ..Additionally, responding to changes in saccade direction (but not amplitude) may rely on basal ganglia circuitry...
  50. ncbi request reprint Individualized alpha activity and frontal asymmetry in major depression
    R A Segrave
    Monash Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology, Psychiatry and Psychological Medicine, Melbourne, Victoria, Australia
    Clin EEG Neurosci 42:45-52. 2011
    ..The relevance of this finding is discussed in relation to the electrophysiological correlates of antidepressant medication use, lateralized differences in affective processing and treatment resistant MDD...
  51. ncbi request reprint Effects of rTMS on an auditory oddball task: a pilot study of cortical plasticity and the EEG
    N R Cooper
    Alfred Psychiatry Research Centre, Department of Psychological Medicine, Monash University, Melbourne, Australia
    Clin EEG Neurosci 39:139-43. 2008
    ..No changes were found to oddball-P300 amplitudes or latencies. In conclusion, the findings of less alpha desynchronization post-TMS are compatible with notions of slow rTMS causing a decrease in cortical excitation...
  52. ncbi request reprint A clinical trial of adjunctive oestrogen treatment in women with schizophrenia
    J Kulkarni
    Dandenong Psychiatry Research Centre, Monash University Department of Psychological Medicine, Melbourne, Australia
    Arch Womens Ment Health 5:99-104. 2002
    ..The positive impact of oestrogen treatment on psychotic symptoms via a multiplicity of possible actions (see accompanying articles in this issue) may prove clinically useful in the overall treatment of women with schizophrenia...
  53. doi request reprint A prospective study of the impact of subthreshold mixed states on the 24-month clinical outcomes of bipolar I disorder or schizoaffective disorder
    S Dodd
    Department of Clinical and Biomedical Sciences Barwon Health, The University of Melbourne, Geelong, Victoria, Australia
    J Affect Disord 124:22-8. 2010
    ..This study investigated the clinical outcomes in participants with bipolar I disorder or schizoaffective disorder, using the Cassidy and Benazzi criteria for manic and depressive mixed states, respectively...
  54. ncbi request reprint Ocular motor differences between melancholic and non-melancholic depression
    C Winograd-Gurvich
    Experimental Neuropsychology Research Unit, School of Psychology, Psychiatry and Psychological Medicine, Monash University, Melbourne 3800, Australia
    J Affect Disord 93:193-203. 2006
    ..Eye movement studies in depression are infrequent and findings are inconclusive...
  55. ncbi request reprint A pilot study of hormone modulation as a new treatment for mania in women with bipolar affective disorder
    Jayashri Kulkarni
    Alfred Psychiatry Research Centre, The Alfred Hospital, Commercial Road, Melbourne, Victoria 3004, Australia
    Psychoneuroendocrinology 31:543-7. 2006
    ..The MPA group improved more than the placebo group. Further exploration of tamoxifen as a useful adjunct in the treatment of acute manic symptoms in women with Bipolar Affective Disorder is warranted...
  56. ncbi request reprint Preliminary findings from the National Register of Antipsychotic Medication in Pregnancy
    Jayashri Kulkarni
    Alfred Psychiatry Research Centre, Level 1, Old Baker Building, Alfred Hospital, Melbourne, Vic, Australia 3004
    Aust N Z J Psychiatry 42:38-44. 2008
    ....
  57. pmc Motor overflow in Huntington's disease
    N Georgiou-Karistianis
    Experimental Neuropsychology Research Unit, Psychology Department, School of Psychology, Psychiatry and Psychological Medicine, Monash University, Clayton, Victoria, Australia
    J Neurol Neurosurg Psychiatry 75:904-6. 2004
    ..The presence of exacerbated motor overflow in HD, and its correlation with symptom severity, is an important finding worthy of further investigation...
  58. doi request reprint Concurrent cognitive control training augments the antidepressant efficacy of tDCS: a pilot study
    R A Segrave
    Monash University, Central Clinical School, Monash Alfred Psychiatry Research Centre, Level 4, 607 St Kilda Rd, Prahran, VIC 3004, Australia Electronic address
    Brain Stimul 7:325-31. 2014
    ..Concurrent cognitive activity has been shown to enhance tDCS induced stimulation effects. Cognitive control training (CCT) is a new cognitive therapy for MDD that aims to enhance DLPFC activity via behavioral methods...
  59. doi request reprint The cost of relapse in schizophrenia and schizoaffective disorder
    Paul Fitzgerald
    The Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology, Psychiatry and Psychological Medicine, Prahran, Vic, Australia
    Australas Psychiatry 17:265-72. 2009
    ..The aim of this study was to quantify the costs and resource utilization associated with a relapse of schizophrenia or schizoaffective disorder...
  60. doi request reprint Brain stimulation techniques for the treatment of depression and other psychiatric disorders
    Paul Fitzgerald
    Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology, Psychiatry and Psychological Medicine, Vic, Australia
    Australas Psychiatry 16:183-90. 2008
    ....
  61. ncbi request reprint Australian Schizophrenia Care and Assessment Programme: real-world schizophrenia: outcomes
    Jayashri Kulkarni
    Alfred Psychiatry Research Centre, Alfred and Monash University School of Psychology, Psychiatry and Psychological Medicine, Alfred Hospital, Melbourne, Vic, Australia
    Aust N Z J Psychiatry 41:969-79. 2007
    ....
  62. ncbi request reprint Self-paced and reprogrammed saccades: differences between melancholic and non-melancholic depression
    Caroline Winograd-Gurvich
    Experimental Neuropsychology Research Unit, School of Psychology, Psychiatry and Psychological Medicine, Monash University, Clayton, Victoria 3800, Australia
    Neurosci Res 56:253-60. 2006
    ..These findings provide further support for distinct motor impairments associated with melancholia that may reflect frontostriatal abnormalities...
  63. ncbi request reprint Using transcranial magnetic stimulation to investigate the cortical origins of motor overflow: a study in schizophrenia and healthy controls
    Kate E Hoy
    Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology, Psychiatry and Psychological Medicine, Melbourne, Australia
    Psychol Med 37:583-94. 2007
    ..In contrast, bilaterally active corticospinal tracts accounting for overflow probably represent a naturally occurring response during fatiguing contractions...
  64. ncbi request reprint The effects of repetitive transcranial magnetic stimulation on cortical inhibition in healthy human subjects
    Zafiris J Daskalakis
    Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, Canada
    Exp Brain Res 174:403-12. 2006
    ..Baseline physiological characteristics may be further explored as a method to select patients who may benefit from rTMS treatment...
  65. ncbi request reprint Reduced cerebellar inhibition in schizophrenia: a preliminary study
    Zafiris J Daskalakis
    Schizophrenia Program, Centre for Addiction and Mental Health, University of Toronto, Ont M5T 1R8, Canada
    Am J Psychiatry 162:1203-5. 2005
    ..The authors' goal was to use transcranial magnetic stimulation to measure cerebellar inhibition, a proxy of cerebellar activity, as the principal output of the cerebellum is inhibitory...
  66. ncbi request reprint Investigating the cortical origins of motor overflow
    Kate E Hoy
    Experimental Neuropsychology Research Unit, Psychology Department, Monash University, Clayton 3800, Victoria, Australia
    Brain Res Brain Res Rev 46:315-27. 2004
    ..This exploration is done in the context of a range of neurological and psychiatric disorders, in order to elucidate the possible underlying mechanisms of overflow...
  67. ncbi request reprint Repetitive transcranial magnetic stimulation reveals abnormal plastic response to premotor cortex stimulation in schizophrenia
    Tom Oxley
    Alfred Psychiatry Research Centre, Department of Psychological Medicine, The Alfred and Monash University, Melbourne, Victoria, Australia 3004
    Biol Psychiatry 56:628-33. 2004
    ..We hypothesized that premotor rTMS would cause less suppression of motor cortical excitability in patients with schizophrenia than in control subjects...
  68. ncbi request reprint Transcranial magnetic stimulation: a new investigational and treatment tool in psychiatry
    Zafiris J Daskalakis
    Schizophrenia and Continuing Care Program, Centre for Addiction and Mental Health, 7th Floor Clarke Division, University of Toronto, 250 College Street, Toronto, Ontario, Canada
    J Neuropsychiatry Clin Neurosci 14:406-15. 2002
    ..The most serious side effect of high-frequency rTMS is seizures. TMS represents an exciting new frontier in neuroscience research, providing insights into the pathophysiology and treatment of various neuropsychiatric disorders...
  69. pmc Exploring the connectivity between the cerebellum and motor cortex in humans
    Zafiris J Daskalakis
    Schizophrenia Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    J Physiol 557:689-700. 2004
    ..The third experiment showed that the interaction between CBI and LICI reduced CBI. Collectively, these findings suggest that cerebellar stimulation results in changes to both inhibitory and excitatory neurones in the human motor cortex...
  70. ncbi request reprint Motor overflow in schizophrenia
    Kate E Hoy
    Experimental Neuropsychology Research Unit, Psychology Department, Monash University, Clayton 3800, Victoria, Australia
    Psychiatry Res 125:129-37. 2004
    ..In summary, patients differed significantly from controls in both the degree and pattern of overflow exhibited...
  71. ncbi request reprint Effect of antipsychotics on cortical inhibition using transcranial magnetic stimulation
    Zafiris J Daskalakis
    Schizophrenia Program, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Psychopharmacology (Berl) 170:255-62. 2003
    ..Therefore, single administration of an antipsychotic has no effect on CI or resting motor threshold. Whether chronic, repeated administration of antipsychotics has effects on CI requires further investigation...
  72. pmc The mechanisms of interhemispheric inhibition in the human motor cortex
    Zafiris J Daskalakis
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    J Physiol 543:317-26. 2002
    ..In contrast, the mechanisms mediating short interval intracortical inhibition are probably different from those mediating long interval intracortical inhibition and interhemispheric inhibition although these systems appear to interact...
  73. ncbi request reprint Evidence for impaired cortical inhibition in schizophrenia using transcranial magnetic stimulation
    Zafiris J Daskalakis
    Schizophrenia and Continuing Care Program, Centre for Addiction and Mental Health, Department of Psychiatry, Toronto Western General Hospital, University of Toronto, Ontario, Canada
    Arch Gen Psychiatry 59:347-54. 2002
    ....
  74. ncbi request reprint Inhibitory control and spatial working memory in Parkinson's disease
    Caroline Gurvich
    Experimental Neuropsychology Research Unit, School of Psychology, Psychiatry and Psychological Medicine, Monash University, Clayton, Victoria, Australia
    Mov Disord 22:1444-50. 2007
    ..These findings are consistent with dysfunction within fronto-striatal and prefrontal-collicular pathways influencing suppression and selection of eye movements...
  75. doi request reprint Saccadic impairment in schizophrenia with prominent negative symptoms
    Caroline T Gurvich
    Monash Alfred Psychiatry Research Centre, Alfred Hospital, Monash University School of Psychology, Psychiatry and Psychological Medicine, Prahran, Victoria 3004, Australia
    Neuroreport 19:1435-9. 2008
    ..It is possible that increased variability may reflect frontostriatal impairments and increased peak velocity may reflect serotonin changes or prefrontal cortex dysfunction...
  76. ncbi request reprint The use of tDCS and CVS as methods of non-invasive brain stimulation
    Gregory Been
    Alfred Psychiatry Research Centre, The Alfred Hospital and Monash University School of Psychology, Psychiatry and Psychological Medicine, Commercial Rd, Melbourne, VIC 3004, Australia
    Brain Res Rev 56:346-61. 2007
    ..Importantly, they are both inexpensive relative to other brain stimulation techniques such as electroconvulsive therapy (ECT) and transcranial magnetic stimulation (TMS)...
  77. ncbi request reprint Inhibitory control and spatial working memory: a saccadic eye movement study of negative symptoms in schizophrenia
    Caroline Winograd-Gurvich
    Experimental Neuropsychology Research Unit, School of Psychology, Psychiatry and Psychological Medicine, Monash University, Clayton, Victoria, 3800, Australia
    Psychiatry Res 157:9-19. 2008
    ..Collectively, these findings provide further support for the proposed association between prefrontal dysfunction and negative symptoms...
  78. ncbi request reprint The Bipolar Comprehensive Outcomes Study (BCOS): baseline findings of an Australian cohort study
    Jayashri Kulkarni
    Alfred Psychiatry Research Centre, The Alfred and Monash University, School of Psychology, Psychiatry and Psychological Medicine, Commercial Road, Melbourne VIC 3004, Australia
    J Affect Disord 107:135-44. 2008
    ..The Bipolar Comprehensive Outcomes Study (BCOS) is a 2-year, observational study of participants with bipolar I or schizoaffective disorder examining clinical, functional, and economic outcomes associated with naturalistic treatment...
  79. doi request reprint Increased cortical inhibition in persons with schizophrenia treated with clozapine
    Zafiris J Daskalakis
    Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada
    J Psychopharmacol 22:203-9. 2008
    ..Our results also confirm previous findings suggesting that deficits in CI are related to the severity of psychotic symptoms in persons with schizophrenia...
  80. doi request reprint Dysfunctional neural plasticity in patients with schizophrenia
    Zafiris J Daskalakis
    Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Arch Gen Psychiatry 65:378-85. 2008
    ..In schizophrenia, dysfunctional neural plasticity has been proposed as a key pathophysiological mechanism...
  81. doi request reprint Reduced motor facilitation during action observation in schizophrenia: a mirror neuron deficit?
    Peter G Enticott
    Alfred Psychiatry Research Centre, School of Psychology, Psychiatry and Psychological Medicine, Monash University and the Alfred, Australia
    Schizophr Res 102:116-21. 2008
    ..Dysfunction within the mirror neuron system may contribute to the pathophysiology of schizophrenia...
  82. doi request reprint A magnetic resonance imaging study of the entorhinal cortex in treatment-resistant depression
    Christina P Furtado
    Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology, Psychiatry and Psychological Medicine, Melbourne, Victoria 3004, Australia
    Psychiatry Res 163:133-42. 2008
    ..Confirmatory longitudinal studies are required to determine whether these abnormalities predate the onset of depression or are the result of a more chronic, treatment-resistant course of illness...
  83. ncbi request reprint Cortical inhibitory dysfunction in bipolar disorder: a study using transcranial magnetic stimulation
    Andrea J Levinson
    Mood and Anxiety Division, Centre for Addiction and Mental Health, University of Toronto, Ontario, Canada
    J Clin Psychopharmacol 27:493-7. 2007
    ..Using 3 transcranial magnetic stimulation paradigms, known as short-interval CI (SICI), cortical silent period (SP), and interhemispheric inhibition (IHI), the authors measured inhibition in the motor cortex...
  84. doi request reprint Estrogen in severe mental illness: a potential new treatment approach
    Jayashri Kulkarni
    Alfred Psychiatry Research Centre, The Alfred and Monash University, School of Psychology, Psychiatry, and Psychological Medicine, The Alfred Hospital, Melbourne, Victoria 3004, Australia
    Arch Gen Psychiatry 65:955-60. 2008
    ..Accumulating evidence suggests that estrogens may have therapeutic effects in severe mental illnesses, including schizophrenia, via neuromodulatory and neuroprotective activity...
  85. ncbi request reprint Evidence for impaired long-term potentiation in schizophrenia and its relationship to motor skill learning
    Marina V Frantseva
    Schizophrenia Program, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Cereb Cortex 18:990-6. 2008
    ..These data provide evidence for disrupted LTP in SCZ, whereas the association between LTP with motor skill learning suggests that the deficits in learning and memory in SCZ may be mediated through disordered LTP...
  86. ncbi request reprint Long-term effects of left frontal rTMS on EEG and ERPs in patients with depression
    Desirée Spronk
    Brainclinics Diagnostics B V, Nijmegen, The Netherlands
    Clin EEG Neurosci 39:118-24. 2008
    ..The findings from this pilot study require future replication with larger sample sizes...
  87. ncbi request reprint Relationship between P50 suppression and the cortical silent period
    Bertram Moller
    Schizophrenia Program, Centre for Addiction and Mental Health, Universty of Toronto, 250 College Street, M5T IR8, Toronto, Ontario, Canada
    Neuroreport 18:1503-6. 2007
    ....
  88. ncbi request reprint Evaluating the relationship between long interval cortical inhibition, working memory and gamma band activity in the dorsolateral prefrontal cortex
    Zafiris J Daskalakis
    Centre for Addiction and Mental Health, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    Clin EEG Neurosci 39:150-5. 2008
    ..However, our data does suggest that LICI was related to 3-back performance providing evidence implicating DLPFC GABAergic inhibitory neurotransmission in WM performance...
  89. doi request reprint Mirror neuron activation is associated with facial emotion processing
    Peter G Enticott
    Alfred Psychiatry Research Centre, School of Psychology, Psychiatry and Psychological Medicine, Monash University and the Alfred, Melbourne, Victoria 3004, Australia
    Neuropsychologia 46:2851-4. 2008
    ..We discuss the mechanism by which mirror neurons might facilitate facial emotion recognition...