Harold A Coleman

Summary

Affiliation: Monash University
Country: Australia

Publications

  1. ncbi request reprint Endothelial potassium channels, endothelium-dependent hyperpolarization and the regulation of vascular tone in health and disease
    Harold A Coleman
    Department of Physiology, Monash University, Melbourne, Victoria, Australia
    Clin Exp Pharmacol Physiol 31:641-9. 2004
  2. pmc Vitamin D insufficiency is associated with impaired vascular endothelial and smooth muscle function and hypertension in young rats
    Marianne Tare
    Department of Physiology, Monash University, Victoria 3800, Australia
    J Physiol 589:4777-86. 2011
  3. pmc Role for endothelium-derived hyperpolarizing factor in vascular tone in rat mesenteric and hindlimb circulations in vivo
    Helena C Parkington
    Department of Physiology, Monash University, Clayton, Victoria 3800, Australia
    J Physiol 542:929-37. 2002
  4. pmc Comparative study on the therapeutic potential of neurally differentiated stem cells in a mouse model of multiple sclerosis
    Natalie L Payne
    Monash Immunology and Stem Cell Laboratories, Monash University, Clayton, Victoria, Australia
    PLoS ONE 7:e35093. 2012
  5. doi request reprint Prenatal alcohol exposure: implications for cardiovascular function in the fetus and beyond
    Helena C Parkington
    Department of Physiology, Monash University, Melbourne, Victoria, Australia
    Clin Exp Pharmacol Physiol 37:e91-8. 2010
  6. ncbi request reprint Myoendothelial electrical coupling in arteries and arterioles and its implications for endothelium-derived hyperpolarizing factor
    Harold A Coleman
    Department of Physiology, Monash University, Melbourne, Victoria, Australia
    Clin Exp Pharmacol Physiol 29:630-7. 2002
  7. ncbi request reprint Selective increase in renal arcuate innervation density and neurogenic constriction in chronic angiotensin II-infused rats
    Helena C Parkington
    Department of Physiology, Monash University, Victoria, 3800, Australia
    Hypertension 43:643-8. 2004
  8. ncbi request reprint Prostacyclin and endothelium-dependent hyperpolarization
    Helena C Parkington
    Department of Physiology, Monash University, Victoria 3800, Australia
    Pharmacol Res 49:509-14. 2004
  9. doi request reprint Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory
    Katherine R Martin
    Department of Biochemistry and Molecular Biology, Monash University, Clayton, 3168 Victoria, Australia
    Hum Mol Genet 21:3025-41. 2012
  10. doi request reprint Effect of maternal administration of allopregnanolone before birth asphyxia on neonatal hippocampal function in the spiny mouse
    Bobbi Fleiss
    Department of Physiology, Monash University, Clayton, Victoria 3800, Australia
    Brain Res 1433:9-19. 2012

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Endothelial potassium channels, endothelium-dependent hyperpolarization and the regulation of vascular tone in health and disease
    Harold A Coleman
    Department of Physiology, Monash University, Melbourne, Victoria, Australia
    Clin Exp Pharmacol Physiol 31:641-9. 2004
    ..The resulting endothelial hyperpolarization spreads via myoendothelial gap junctions to result in the EDHF-attributed hyperpolarization and relaxation of the smooth muscle...
  2. pmc Vitamin D insufficiency is associated with impaired vascular endothelial and smooth muscle function and hypertension in young rats
    Marianne Tare
    Department of Physiology, Monash University, Victoria 3800, Australia
    J Physiol 589:4777-86. 2011
    ..In conclusion, early life vitamin D deficiency is associated with endothelial vasodilator dysfunction, and this is likely to contribute to the accompanying elevation in blood pressure and an increased cardiovascular disease risk...
  3. pmc Role for endothelium-derived hyperpolarizing factor in vascular tone in rat mesenteric and hindlimb circulations in vivo
    Helena C Parkington
    Department of Physiology, Monash University, Clayton, Victoria 3800, Australia
    J Physiol 542:929-37. 2002
    ..However, EDHF accounts for a significant component of the conductance increase during endothelial stimulation by ACh and BK. In these beds, intermediate- and small-conductance K(Ca) channels underpin EDHF-mediated vasodilatation...
  4. pmc Comparative study on the therapeutic potential of neurally differentiated stem cells in a mouse model of multiple sclerosis
    Natalie L Payne
    Monash Immunology and Stem Cell Laboratories, Monash University, Clayton, Victoria, Australia
    PLoS ONE 7:e35093. 2012
    ....
  5. doi request reprint Prenatal alcohol exposure: implications for cardiovascular function in the fetus and beyond
    Helena C Parkington
    Department of Physiology, Monash University, Melbourne, Victoria, Australia
    Clin Exp Pharmacol Physiol 37:e91-8. 2010
    ..4. It is envisaged that the culmination of reduced renal and vascular capacity will render the offspring more vulnerable to cardiovascular disease with ageing and exposure to additional insults and lifestyle factors...
  6. ncbi request reprint Myoendothelial electrical coupling in arteries and arterioles and its implications for endothelium-derived hyperpolarizing factor
    Harold A Coleman
    Department of Physiology, Monash University, Melbourne, Victoria, Australia
    Clin Exp Pharmacol Physiol 29:630-7. 2002
    ..Because this hyperpolarization can evoke considerable relaxation of the smooth muscle, myoendothelial electrical coupling has important implications for endothelial regulation of the contractile activity of blood vessels...
  7. ncbi request reprint Selective increase in renal arcuate innervation density and neurogenic constriction in chronic angiotensin II-infused rats
    Helena C Parkington
    Department of Physiology, Monash University, Victoria, 3800, Australia
    Hypertension 43:643-8. 2004
    ..These changes appear early and occur before changes in renal endothelial function are apparent. Thus, "slow pressor" angiotensin II hypertension is associated with increased renal innervation, compatible with a pathogenetic role...
  8. ncbi request reprint Prostacyclin and endothelium-dependent hyperpolarization
    Helena C Parkington
    Department of Physiology, Monash University, Victoria 3800, Australia
    Pharmacol Res 49:509-14. 2004
    ..Emerging information suggests that these drugs may impact on endothelial prostacyclin production, with less than optimal consequences for thrombus formation and vasodilation...
  9. doi request reprint Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory
    Katherine R Martin
    Department of Biochemistry and Molecular Biology, Monash University, Clayton, 3168 Victoria, Australia
    Hum Mol Genet 21:3025-41. 2012
    ..Our data strongly suggest that RCAN1 plays an important role in normal brain development and function and its up-regulation likely contributes to the neural deficits associated with DS...
  10. doi request reprint Effect of maternal administration of allopregnanolone before birth asphyxia on neonatal hippocampal function in the spiny mouse
    Bobbi Fleiss
    Department of Physiology, Monash University, Clayton, Victoria 3800, Australia
    Brain Res 1433:9-19. 2012
    ..Best practice for treatment dose and timing of treatment will need to be carefully considered...
  11. doi request reprint Estradiol-17beta inhibits gonadotropin-releasing hormone-induced Ca2+ in gonadotropes to regulate negative feedback on luteinizing hormone release
    Javed Iqbal
    Department of Physiology, Monash University, Clayton, Victoria 3800, Australia
    Endocrinology 150:4213-20. 2009
    ..Activation of the MAPK pathway by E(2) may be the mechanism for the time-delayed positive feedback effect on LH secretion at the level of the gonadotrope...
  12. ncbi request reprint Involvement of myoendothelial gap junctions in the actions of endothelium-derived hyperpolarizing factor
    Shaun L Sandow
    Department of Physiology, Monash University, Clayton, Victoria, Australia
    Circ Res 90:1108-13. 2002
    ..These results show that transfer of EC hyperpolarization or of a small molecule to SMCs through MEGJs is essential and sufficient to explain EDHF...
  13. ncbi request reprint Null mutation of the alpha4 nicotinic receptor subunit increases the propensity of muscarinic-mediated neuronal bursting in mouse hippocampal slices
    Christopher A Reid
    Department of Medicine, Monash Medical Centre, Monash University, Melbourne, VIC 3800, Australia
    Neuropharmacology 51:587-96. 2006
    ....
  14. ncbi request reprint Transthyretin oligomers induce calcium influx via voltage-gated calcium channels
    Xu Hou
    Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia
    J Neurochem 100:446-57. 2007
    ..These results suggest that increasing [Ca(2+)](i) via VGCCs may be an important early event which contributes to TTR-induced cytotoxicity, and that TTR oligomers, rather than mature fibrils, may be the major cytotoxic form of TTR...
  15. pmc Pulmonary delivery of an ultra-fine oxytocin dry powder formulation: potential for treatment of postpartum haemorrhage in developing countries
    Richard J Prankerd
    Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia
    PLoS ONE 8:e82965. 2013
    ..Aerosolised oxytocin has the potential to provide a stable and easy to administer delivery system for effective prevention and treatment of postpartum haemorrhage in resource-poor settings in the developing world. ..
  16. doi request reprint Neural differentiation of patient specific iPS cells as a novel approach to study the pathophysiology of multiple sclerosis
    Bi Song
    Monash Immunology and Stem Cell Laboratories, Monash University, Wellington Road, Clayton, Victoria 3800, Australia
    Stem Cell Res 8:259-73. 2012
    ..This represents an important step in a novel approach for the study of MS pathophysiology and potential drug discovery...
  17. doi request reprint Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells
    Maria Kaparakis
    Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia
    Cell Microbiol 12:372-85. 2010
    ..We propose that OMVs released by bacteria in vivo may promote inflammation and pathology in infected hosts...
  18. ncbi request reprint Evidence for the involvement of myoendothelial gap junctions in EDHF-mediated relaxation in the rat middle cerebral artery
    Elke M Sokoya
    Department of Anesthesiology, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Physiol Heart Circ Physiol 291:H385-93. 2006
    ..The total number of myoendothelial junctions per 5 microm of MCA sectioned was 2.5 +/- 0.5. Our results suggest that myoendothelial communication contributes to smooth muscle cell hyperpolarization and EDHF dilation in male rat MCA...
  19. pmc Reduced vascular reactivity after chronic nitroglycerine administration: EDHF mechanism is also downregulated
    Pierre Yves von der Weid
    Mucosal Inflammation and Smooth Muscle Research Groups, Department of Physiology and Biophysics, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    Br J Pharmacol 146:479-80. 2005
  20. doi request reprint The EDHF story: the plot thickens
    Helena C Parkington
    Circ Res 102:1148-50. 2008