Feng Chen

Summary

Affiliation: Monash University
Country: Australia

Publications

  1. ncbi request reprint Up-regulation of cortical AMPA receptor binding in the fawn-hooded rat following ethanol withdrawal
    F Chen
    Department of Pharmacology, Monash University, Wellington Road, Clayton, Victoria, 3168, Australia
    Eur J Pharmacol 384:139-46. 1999
  2. ncbi request reprint 5-HT transporter sites and 5-HT1A and 5-HT3 receptors in Fawn-Hooded rats: a quantitative autoradiography study
    F Chen
    Department of Pharmacology, Monash University, Clayton, Victoria, Australia
    Alcohol Clin Exp Res 24:1093-102. 2000
  3. ncbi request reprint Autoradiographic quantification of neurochemical markers of serotonin, dopamine and opioid systems in rat brain mesolimbic regions following chronic St John's wort treatment
    Feng Chen
    Department of Pharmacology, Faculty of Medicine, Monash University, Wellington Road, PO Box 13E, 3800, Clayton, Victoria, Australia
    Naunyn Schmiedebergs Arch Pharmacol 367:126-33. 2003
  4. ncbi request reprint The effects of antidepressant treatment on serotonergic and dopaminergic systems in Fawn-Hooded rats: a quantitative autoradiography study
    Feng Chen
    Department of Pharmacology, Faculty of Medicine, Monash University, Clayton, Victoria 3800, Australia
    Brain Res 976:22-9. 2003
  5. doi request reprint AT1 receptors in the paraventricular nucleus mediate the hyperthermia-induced reflex reduction of renal blood flow in rats
    Feng Chen
    School of Medical Sciences, Royal Melbourne Institute of Technology University, P O Box 71, Bundoora 3083, Melbourne, Victoria, Australia
    Am J Physiol Regul Integr Comp Physiol 300:R479-85. 2011
  6. doi request reprint Inhibition of nitric oxide synthase in the paraventricular nucleus prevents the hyperthermia-induced reduction of mesenteric blood flow in rats
    Feng Chen
    School of Medical Sciences, RMIT Univ, PO Box 71, Bundoora 3083, Melbourne, Victoria, Australia
    Am J Physiol Regul Integr Comp Physiol 299:R596-602. 2010
  7. doi request reprint Long-term administration of cocaine or serotonin reuptake inhibitors results in anatomical and neurochemical changes in noradrenergic, dopaminergic, and serotonin pathways
    Malcolm K Horne
    Brain Injury and Repair, Howard Florey Institute, and Centre for Neuroscience, University of Melbourne, Parkville, Victoria, Australia
    J Neurochem 106:1731-44. 2008
  8. doi request reprint Cocaine-mediated synaptic potentiation is absent in VTA neurons from mGlu5-deficient mice
    Michael K Bird
    Howard Florey Institute, University of Melbourne, Parkville, Victoria, Australia
    Int J Neuropsychopharmacol 13:133-41. 2010
  9. doi request reprint High-fat feeding alters the cardiovascular role of the hypothalamic paraventricular nucleus
    Feng Chen
    School of Medical Sciences and Health Innovations Research Institute, RMIT University, Victoria, Australia
    Am J Physiol Regul Integr Comp Physiol 298:R799-807. 2010
  10. ncbi request reprint Increased anxiety 3 months after brief exposure to MDMA ("Ecstasy") in rats: association with altered 5-HT transporter and receptor density
    Iain S McGregor
    School of Psychology, University of Sydney, A19, NSW 2006, Australia
    Neuropsychopharmacology 28:1472-84. 2003

Collaborators

  • A J Lawrence
  • Fang Liu
  • Malcolm K Horne
  • COLIN DUCKETT
  • D H Overstreet
  • X-F Huang
  • Hua Bin Li
  • Ka Wing Cheng
  • Hyun Jin Kim
  • Meiling Lu
  • Michael K Bird
  • Marie Van De Putte
  • Feng Li
  • Mingfu Wang
  • Changqing Wu
  • Xi Wang
  • Xiao M Androulakis
  • Jia Jun Liu
  • Vincent L Cryns
  • Merideth C Kamradt
  • Toni Kwan
  • Chunjiang Yu
  • V Craig Jordan
  • Yue Jiang
  • D Siva Sundara Kumar
  • Iain S McGregor
  • Heneu O Tan
  • Steven Petrou
  • Christopher A Reid
  • Xuping Qin
  • Lanfang Li
  • Peter A M de Witte
  • Yicheng Ni
  • Linxi Chen
  • Weinan Pan
  • Fen Feng
  • Huaijun Wang
  • Herbert Tanowitz
  • Bingyan Zhu
  • Chris Albanese
  • Duanfang Liao
  • Zong Ping Zheng
  • Qingli Wu
  • Xiaofang Peng
  • James E Simon
  • Guoqing He
  • George Huang
  • Boubacar Toure
  • Stephanie J Muga
  • Vivian Haley-Zitlin
  • Michael J Wargovich
  • Ju Hee Choi
  • Youssouf Koita
  • James W Rushing
  • Mao Hong Zhang
  • Xianglin Pan
  • Albert F LoBuglio
  • Yu Qin Song
  • Shayna Oshita
  • Ren Wei Huang
  • Patsy G Oliver
  • Michael E Werner
  • J Larry Jameson
  • John C Wilkinson
  • Xiang Yuan Wu
  • Eun Jig Lee
  • Jun Peng
  • Ming Hou
  • Jennifer M Schafer
  • Dong Jun Lin
  • Bethany Freedman
  • Anne Strohecker
  • Donald J Buchsbaum
  • Qu Lin
  • Kevin D Hyde
  • Hai tao Lu
  • Chak Sing Lau
  • Hon Yeung Cheung
  • Glenn E Hunt
  • Kelly J Clemens
  • Geoffrey Van der Plasse
  • Kong M Li

Detail Information

Publications30

  1. ncbi request reprint Up-regulation of cortical AMPA receptor binding in the fawn-hooded rat following ethanol withdrawal
    F Chen
    Department of Pharmacology, Monash University, Wellington Road, Clayton, Victoria, 3168, Australia
    Eur J Pharmacol 384:139-46. 1999
    ..The findings suggest that AMPA receptors in frontal cortical regions are sensitive to ethanol and therefore may be implicated in the predisposition of alcohol preference in FH rats...
  2. ncbi request reprint 5-HT transporter sites and 5-HT1A and 5-HT3 receptors in Fawn-Hooded rats: a quantitative autoradiography study
    F Chen
    Department of Pharmacology, Monash University, Clayton, Victoria, Australia
    Alcohol Clin Exp Res 24:1093-102. 2000
    ..The neuroanatomical profiles of 5-HT1A receptors, 5-HT3 receptors, and 5-HT transporters (5-HTT) in the brain of the Fawn-Hooded (FH) rat, particularly mesocorticolimbic regions, are not fully elucidated...
  3. ncbi request reprint Autoradiographic quantification of neurochemical markers of serotonin, dopamine and opioid systems in rat brain mesolimbic regions following chronic St John's wort treatment
    Feng Chen
    Department of Pharmacology, Faculty of Medicine, Monash University, Wellington Road, PO Box 13E, 3800, Clayton, Victoria, Australia
    Naunyn Schmiedebergs Arch Pharmacol 367:126-33. 2003
    ....
  4. ncbi request reprint The effects of antidepressant treatment on serotonergic and dopaminergic systems in Fawn-Hooded rats: a quantitative autoradiography study
    Feng Chen
    Department of Pharmacology, Faculty of Medicine, Monash University, Clayton, Victoria 3800, Australia
    Brain Res 976:22-9. 2003
    ....
  5. doi request reprint AT1 receptors in the paraventricular nucleus mediate the hyperthermia-induced reflex reduction of renal blood flow in rats
    Feng Chen
    School of Medical Sciences, Royal Melbourne Institute of Technology University, P O Box 71, Bundoora 3083, Melbourne, Victoria, Australia
    Am J Physiol Regul Integr Comp Physiol 300:R479-85. 2011
    ..The results suggest that endogenous ANG II acts on AT1 receptors in the PVN to mediate the reduction in RBF induced by hyperthermia...
  6. doi request reprint Inhibition of nitric oxide synthase in the paraventricular nucleus prevents the hyperthermia-induced reduction of mesenteric blood flow in rats
    Feng Chen
    School of Medical Sciences, RMIT Univ, PO Box 71, Bundoora 3083, Melbourne, Victoria, Australia
    Am J Physiol Regul Integr Comp Physiol 299:R596-602. 2010
    ..In the absence of hyperthermia, however, endogenous NO in the PVN may play a role in maintaining mesenteric vasodilation...
  7. doi request reprint Long-term administration of cocaine or serotonin reuptake inhibitors results in anatomical and neurochemical changes in noradrenergic, dopaminergic, and serotonin pathways
    Malcolm K Horne
    Brain Injury and Repair, Howard Florey Institute, and Centre for Neuroscience, University of Melbourne, Parkville, Victoria, Australia
    J Neurochem 106:1731-44. 2008
    ..Moreover, our data suggest that drug-induced plastic adaptation is anatomically widespread and consequently, likely to have multiple and complex consequences...
  8. doi request reprint Cocaine-mediated synaptic potentiation is absent in VTA neurons from mGlu5-deficient mice
    Michael K Bird
    Howard Florey Institute, University of Melbourne, Parkville, Victoria, Australia
    Int J Neuropsychopharmacol 13:133-41. 2010
    ..In contrast, the mGlu5 receptor may not be essential for psychostimulant behavioural sensitization; although it probably impacts other aspects drug addiction, such as motivation to self-administer...
  9. doi request reprint High-fat feeding alters the cardiovascular role of the hypothalamic paraventricular nucleus
    Feng Chen
    School of Medical Sciences and Health Innovations Research Institute, RMIT University, Victoria, Australia
    Am J Physiol Regul Integr Comp Physiol 298:R799-807. 2010
    ..In conclusion, the role of the paraventricular nucleus in cardiovascular regulation can be altered by a diet high in fat, even when hypertension and obesity are absent...
  10. ncbi request reprint Increased anxiety 3 months after brief exposure to MDMA ("Ecstasy") in rats: association with altered 5-HT transporter and receptor density
    Iain S McGregor
    School of Psychology, University of Sydney, A19, NSW 2006, Australia
    Neuropsychopharmacology 28:1472-84. 2003
    ..Interestingly, long-term 5-HT depletion may not be necessary to produce lasting effects on anxiety-like behavior after low-dose MDMA...
  11. ncbi request reprint 5-HT2A/2C receptor and 5-HT transporter densities in mice prone or resistant to chronic high-fat diet-induced obesity: a quantitative autoradiography study
    Xu Feng Huang
    Molecular Neurobiology Laboratory, Smart Food Center, Department of Biomedical Science, University of Wollongong, Northfield Avenue, Wollongong, NSW 2522, Australia
    Brain Res 1018:227-35. 2004
    ..It provides neural anatomical bases by which genetic variability in 5-HT2A/2C receptors and 5-HT transporter may influence satiety and sensory aspects of energy balance...
  12. ncbi request reprint Chronic antidepressant treatment causes a selective reduction of mu-opioid receptor binding and functional coupling to G Proteins in the amygdala of fawn-hooded rats
    Feng Chen
    Howard Florey Institute, The University of Melbourne, Parkville, Victoria 3010, Australia
    J Pharmacol Exp Ther 310:1020-6. 2004
    ....
  13. ncbi request reprint Effect of methyl jasmonate on phenolics, isothiocyanate, and metabolic enzymes in radish sprout (Raphanus sativus L.)
    Hyun Jin Kim
    Department of Food Science and Human Nutrition, Clemson University, Clemson, South Carolina 29634, USA
    J Agric Food Chem 54:7263-9. 2006
    ..However, the same treatment decreased the amount of 4-methylthio-3-butenylisothiocyanate (MTBITC), a major isothiocyanate in radish sprout and the activity of myrosinase, an enzyme related to produce isothiocyanates...
  14. ncbi request reprint Heterocyclic amines: chemistry and health
    Ka Wing Cheng
    Department of Botany, The University of Hong Kong, Hong Kong, PR China
    Mol Nutr Food Res 50:1150-70. 2006
    ..Various inhibitory strategies, ranging from modifying cooking conditions to incorporation of different modulators, have been developed. This will remain one of the foremost areas of research in the field of food chemistry and safety...
  15. ncbi request reprint Preparative purification of glycyrrhizin extracted from the root of liquorice using high-speed counter-current chromatography
    Yue Jiang
    Department of Biology, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
    J Chromatogr A 1033:183-6. 2004
    ..The lower phase was used as the mobile phase in the head-to-tail elution mode. The present method yielded 42.2 mg glycyrrhizin at 96.8% purity from 130 mg of the crude exact with 95.2% recovery as determined by HPLC analysis...
  16. ncbi request reprint Inhibitory effect of fruit extracts on the formation of heterocyclic amines
    Ka Wing Cheng
    School of Biological Sciences, The University of Hong Kong, Pokfulam Road, Hong Kong, P R China
    J Agric Food Chem 55:10359-65. 2007
    ..The findings provide valuable information for the development of effective strategies to minimize HA content of cooked meats and to identify several new natural products that may have new applications in the food industry...
  17. ncbi request reprint Hypericin as a marker for determination of tissue viability after radiofrequency ablation in a murine liver tumor model
    Marie Van De Putte
    Laboratory for Pharmaceutical Biology, Faculty of Pharmaceutical Sciences, B 3000 Leuven, Belgium
    Oncol Rep 19:927-32. 2008
    ..The results suggest that hypericin offers significant potential in the early assessment of response following necrosis-inducing antineoplastic treatments such as RFA...
  18. ncbi request reprint Apelin-induced vascular smooth muscle cell proliferation: the regulation of cyclin D1
    Feng Li
    Institute of Pharmacology and Pharmacy, Nanhua University, Hengyang, China
    Front Biosci 13:3786-92. 2008
    ..Taken together, these data established that apelin-13 stimulates vascular smooth muscle cell proliferation by promoting the G1-S phase transition, and that this effect is mediated in part by an apelin-pERK1/2-cyclin D1 signal cascade...
  19. ncbi request reprint Modulation of high alcohol drinking in the inbred Fawn-Hooded (FH/Wjd) rat strain: implications for treatment
    David H Overstreet
    Bowles Center for Alcohol Studies and Department of Psychiatry, University of North Carolina at Chapel Hill, USA
    Addict Biol 11:356-73. 2006
    ....
  20. ncbi request reprint Chemopreventive effects of Khaya senegalensis bark extract on human colorectal cancer
    Xiao M Androulakis
    Department of Pathology and Microbiology, School of Medicine, University of South Carolina, South Carolina Cancer Center, Columbia, SC 29203, USA
    Anticancer Res 26:2397-405. 2006
    ..Since all three cell lines, irrespective of COX-2 status (HCT-15 is COX-2-deficient), were affected by the treatment, it can be concluded that both COX-dependent and COX-independent pathways are activated by KSBE...
  21. ncbi request reprint Proteolysis of the mismatch repair protein MLH1 by caspase-3 promotes DNA damage-induced apoptosis
    Feng Chen
    Cell Death Regulation Laboratory, Department of Medicine, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    J Biol Chem 279:27542-8. 2004
    ..These results indicate that the proteolysis of MLH1 by caspase-3 plays a functionally important and previously unrecognized role in the execution of DNA damage-induced apoptosis...
  22. ncbi request reprint In vitro studies of endophytic fungi from Tripterygium wilfordii with anti-proliferative activity on human peripheral blood mononuclear cells
    D Siva Sundara Kumar
    Department of Ecology and Biodiversity, Centre for Research in Fungal Diversity, The University of Hong Kong, Hong Kong SAR, PR China
    J Ethnopharmacol 94:295-300. 2004
    ..A and C, Pestalotiopsis suffocata, Morphotype sp. 4 and 5 show a much higher cytotoxic effects on PBMC. Our results indicate that some fungal extracts contain significant amount of immunomodulatory principles...
  23. ncbi request reprint Preparative isolation and purification of chuanxiongzine from the medicinal plant Ligusticum chuanxiong by high-speed counter-current chromatography
    Hua Bin Li
    Department of Botany, University of Hong Kong, Hong Kong, China
    J Chromatogr A 1047:249-53. 2004
    ..5 mg chuanxiongzine at 96.8% purity from 300 mg of the crude extract (4.2% chuanxiongzine) with the recovery of 91% in a one-step separation...
  24. ncbi request reprint Peroxisome proliferator-activated receptor gamma agonists promote TRAIL-induced apoptosis by reducing survivin levels via cyclin D3 repression and cell cycle arrest
    Meiling Lu
    Cell Death Regulation Laboratory, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    J Biol Chem 280:6742-51. 2005
    ..We also demonstrate for the first time that TZDs promote TRAIL-induced apoptosis of breast cancer in vivo, suggesting that this combination may be an effective therapy for cancer...
  25. ncbi request reprint The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3
    Merideth C Kamradt
    Cell Death Regulation Laboratory, Department of Medicine and Cell, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611
    J Biol Chem 280:11059-66. 2005
    ..Moreover, these results demonstrate that targeted inhibition of alpha B-crystallin promotes TRAIL-induced apoptosis, thereby suggesting a novel strategy to overcome TRAIL resistance in cancer...
  26. ncbi request reprint Antiproliferation effects of ponicidin on human myeloid leukemia cells in vitro
    Jia Jun Liu
    Sun Yat Sen University, Department of Haematology and Oncology, The Third Affiliated Hospital of Sun Yat Sen University, Tian He Road 600, Guangzhou, Guangdong 510630, PR China
    Oncol Rep 13:653-7. 2005
    ..The results suggest that ponicidin may serve as a potential therapeutic agent for leukemia...
  27. ncbi request reprint Simultaneous separation and purification of five bioactive coumarins from the Chinese medicinal plant Cnidium monnieri by high-speed counter-current chromatography
    Hua Bin Li
    Department of Botany, University of Hong Kong, Pokfulam Road, Hong Kong
    J Sep Sci 28:268-72. 2005
    ..The five relatively pure coumarins were obtained from 500 mg of the crude extract in a single run. Their purities were 90.6-98.9%, and the recoveries were 85.7-94.2%...
  28. ncbi request reprint Antiproliferative activities of parthenolide and golden feverfew extract against three human cancer cell lines
    Changqing Wu
    Department of Food Science and Human Nutrition, Clemson University, Clemson, South Carolina 29634, USA
    J Med Food 9:55-61. 2006
    ..The results revealed that apigenin and luteolin might have moderate to weak synergistic effects with parthenolide on the inhibition of cancer cell growth of Hs605T, MCF-7, and SiHa...
  29. ncbi request reprint Reductions in levels of the Alzheimer's amyloid beta peptide after oral administration of ginsenosides
    Feng Chen
    Mayo Clinic College of Medicine, Department of Pharmacology, Birdsall Bldg Rm 327, 4500 San Pablo Rd, Jacksonville, Florida 32224, USA
    FASEB J 20:1269-71. 2006
    ..The results indicate that ginseng itself, or purified ginsenosides, may have similarly useful effects in human disease...
  30. ncbi request reprint Preparative isolation and purification of phillyrin from the medicinal plant Forsythia suspensa by high-speed counter-current chromatography
    Hua Bin Li
    Department of Botany, The University of Hong Kong, Pokfulam Road, Hong Kong, China
    J Chromatogr A 1083:102-5. 2005
    ..The method yielded 5.6 mg phillyrin at 98.6% purity from 500 mg of the crude extract (1.2% phillyrin) with the recovery of 92% in a one-step separation...