Robert C Atkins

Summary

Affiliation: Monash University
Country: Australia

Publications

  1. ncbi request reprint Proteinuria reduction and progression to renal failure in patients with type 2 diabetes mellitus and overt nephropathy
    Robert C Atkins
    Department of Nephrology, Monash Medical Centre, Victoria, Australia
    Am J Kidney Dis 45:281-7. 2005
  2. doi request reprint Serum 25-hydroxyvitamin D deficiency and the 5-year incidence of CKD
    Matthew J Damasiewicz
    Department of Nephrology, Monash Medical Centre, Melbourne, Australia
    Am J Kidney Dis 62:58-66. 2013
  3. ncbi request reprint Activation of the extracellular-signal regulated protein kinase pathway in human glomerulopathies
    Takao Masaki
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    J Am Soc Nephrol 15:1835-43. 2004
  4. pmc Nonalbuminuric renal impairment in type 2 diabetic patients and in the general population (national evaluation of the frequency of renal impairment cO-existing with NIDDM [NEFRON] 11)
    Merlin C Thomas
    Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Diabetes Care 32:1497-502. 2009
  5. ncbi request reprint Macrophage accumulation and renal fibrosis are independent of macrophage migration inhibitory factor in mouse obstructive nephropathy
    Edwina K Rice
    Department of Nephrology and Monash University Department of Medicine, Monash Medical Centre, Clayton, Victoria, Australia
    Nephrology (Carlton) 9:278-87. 2004
  6. ncbi request reprint Interferon-gamma induces macrophage migration inhibitory factor synthesis and secretion by tubular epithelial cells
    Edwina K Rice
    Departments of Nephrology and Medicine, Monash Medical Centre, Clayton, Victoria, Australia
    Nephrology (Carlton) 8:156-61. 2003
  7. ncbi request reprint Activation and cellular localization of the p38 and JNK MAPK pathways in rat crescentic glomerulonephritis
    Cosimo Stambe
    Department of Nephrology and Monash University Department of Medicine, Monash Medical Centre, Clayton, Melbourne, Australia
    Kidney Int 64:2121-32. 2003
  8. ncbi request reprint Macrophage-mediated renal injury is dependent on signaling via the JNK pathway
    Yohei Ikezumi
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    J Am Soc Nephrol 15:1775-84. 2004
  9. ncbi request reprint Macrophage colony-stimulating factor expression and macrophage accumulation in renal allograft rejection
    Yannick Le Meur
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Transplantation 73:1318-24. 2002
  10. ncbi request reprint Epidemiology of vascular access in the Australian hemodialysis population
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Centre, Melbourne, Victoria, Australia
    Kidney Int 64:1893-902. 2003

Detail Information

Publications70

  1. ncbi request reprint Proteinuria reduction and progression to renal failure in patients with type 2 diabetes mellitus and overt nephropathy
    Robert C Atkins
    Department of Nephrology, Monash Medical Centre, Victoria, Australia
    Am J Kidney Dis 45:281-7. 2005
    ....
  2. doi request reprint Serum 25-hydroxyvitamin D deficiency and the 5-year incidence of CKD
    Matthew J Damasiewicz
    Department of Nephrology, Monash Medical Centre, Melbourne, Australia
    Am J Kidney Dis 62:58-66. 2013
    ..Low serum 25-hydroxyvitamin D (25[OH]D) levels have been associated with chronic kidney disease in cross-sectional studies. However, this association has not been studied prospectively in a large general population-based cohort...
  3. ncbi request reprint Activation of the extracellular-signal regulated protein kinase pathway in human glomerulopathies
    Takao Masaki
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    J Am Soc Nephrol 15:1835-43. 2004
    ..ERK activation may promote renal repair through tubular proliferation while promoting renal fibrosis via proliferation of glomerular and interstitial myofibroblasts...
  4. pmc Nonalbuminuric renal impairment in type 2 diabetic patients and in the general population (national evaluation of the frequency of renal impairment cO-existing with NIDDM [NEFRON] 11)
    Merlin C Thomas
    Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Diabetes Care 32:1497-502. 2009
    ..However, its impact may be more significant. New studies are required to address the pathogenesis, prevention, and treatment of nonalbuminuric renal disease...
  5. ncbi request reprint Macrophage accumulation and renal fibrosis are independent of macrophage migration inhibitory factor in mouse obstructive nephropathy
    Edwina K Rice
    Department of Nephrology and Monash University Department of Medicine, Monash Medical Centre, Clayton, Victoria, Australia
    Nephrology (Carlton) 9:278-87. 2004
    ..Studies have identified a pathological role for MIF in immune-initiated renal injury in the rat. In this study, we examined the role of MIF in obstructive nephropathy, where renal injury is initiated by a non-immune insult...
  6. ncbi request reprint Interferon-gamma induces macrophage migration inhibitory factor synthesis and secretion by tubular epithelial cells
    Edwina K Rice
    Departments of Nephrology and Medicine, Monash Medical Centre, Clayton, Victoria, Australia
    Nephrology (Carlton) 8:156-61. 2003
    ..These findings indicate that IFN-gamma induces rapid secretion of MIF by tubular epithelial cells, and suggest that this may be an important mechanism leading to inflammatory cell accumulation and activation during kidney disease...
  7. ncbi request reprint Activation and cellular localization of the p38 and JNK MAPK pathways in rat crescentic glomerulonephritis
    Cosimo Stambe
    Department of Nephrology and Monash University Department of Medicine, Monash Medical Centre, Clayton, Melbourne, Australia
    Kidney Int 64:2121-32. 2003
    ..The aim of this study was therefore to delineate the pattern and cellular localization of p38 and JNK activation in normal rat kidney and rat acute and chronic inflammatory renal disease...
  8. ncbi request reprint Macrophage-mediated renal injury is dependent on signaling via the JNK pathway
    Yohei Ikezumi
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    J Am Soc Nephrol 15:1775-84. 2004
    ..01 versus vehicle or untreated BMM). In conclusion, this study has defined a critical role for the JNK signaling pathway in macrophage-mediated renal injury...
  9. ncbi request reprint Macrophage colony-stimulating factor expression and macrophage accumulation in renal allograft rejection
    Yannick Le Meur
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Transplantation 73:1318-24. 2002
    ..We investigated the expression of M-CSF in a model of acute rejection...
  10. ncbi request reprint Epidemiology of vascular access in the Australian hemodialysis population
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Centre, Melbourne, Victoria, Australia
    Kidney Int 64:1893-902. 2003
    ..However, no data are available regarding these factors in a hemodialysis population where AVF utilization is high...
  11. ncbi request reprint The role of p38alpha mitogen-activated protein kinase activation in renal fibrosis
    Cosimo Stambe
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    J Am Soc Nephrol 15:370-9. 2004
    ..Blockade of p38 MAPK reduces extracellular matrix production and may be considered a potential therapeutic option in the treatment of renal fibrosis...
  12. doi request reprint Extracellular signal-regulated kinase-dependent interstitial macrophage proliferation in the obstructed mouse kidney
    Yingjie Han
    Department of Nephrology, Monash Medical Centre, Melbourne, Victoria, Australia
    Nephrology (Carlton) 13:411-8. 2008
    ..The aim of this study was to determine the functional role of ERK signalling in cell proliferation in the obstructed kidney...
  13. ncbi request reprint Macrophages in mouse type 2 diabetic nephropathy: correlation with diabetic state and progressive renal injury
    Fiona Chow
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Kidney Int 65:116-28. 2004
    ..Therefore, we examined whether macrophages may promote the progression of type 2 diabetic nephropathy in db/db mice...
  14. ncbi request reprint Macrophages act as effectors of tissue damage in acute renal allograft rejection
    Matthew D Jose
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Transplantation 76:1015-22. 2003
    ..Macrophages constitute 38% to 60% of infiltrating cells during acute renal allograft rejection. Their contribution to tissue damage during acute rejection was examined by depleting macrophages in a rat model...
  15. ncbi request reprint A pathogenic role for c-Jun amino-terminal kinase signaling in renal fibrosis and tubular cell apoptosis
    Frank Y Ma
    Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia
    J Am Soc Nephrol 18:472-84. 2007
    ..Furthermore, JNK1 plays a nonredundant role in tubular cell apoptosis. These studies identify the JNK pathway as a potential therapeutic target in progressive kidney disease...
  16. pmc 25-Hydroxyvitamin D levels and chronic kidney disease in the AusDiab (Australian Diabetes, Obesity and Lifestyle) study
    Matthew J Damasiewicz
    Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, 3168, Victoria, Australia
    BMC Nephrol 13:55. 2012
    ..We explored the relationship between 25(OH)D levels and prevalent chronic kidney disease (CKD), albuminuria and impaired GFR, in a national, population-based cohort of Australian adults (AusDiab Study)...
  17. ncbi request reprint Intercellular adhesion molecule-1 deficiency is protective against nephropathy in type 2 diabetic db/db mice
    Fiona Y Chow
    Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia
    J Am Soc Nephrol 16:1711-22. 2005
    ..Thus, ICAM-1 appears to be a critical promoter of nephropathy in mouse type 2 diabetes by facilitating kidney macrophage recruitment...
  18. ncbi request reprint Cardiovascular morbidity and mortality in the Atherosclerosis and Folic Acid Supplementation Trial (ASFAST) in chronic renal failure: a multicenter, randomized, controlled trial
    Sophia Zoungas
    Department of Vascular Sciences and Medicine, Centre for Vascular Health, Monash University, Dandenong Hospital, Dandenong, Victoria, Australia
    J Am Coll Cardiol 47:1108-16. 2006
    ..The Atherosclerosis and Folic Acid Supplementation Trial (ASFAST) aimed to establish whether high-dose folic acid would slow the progression of atherosclerosis and reduce cardiovascular events in patients with chronic renal failure (CRF)...
  19. ncbi request reprint Prevalence and treatment of cardiovascular disease and traditional risk factors in Australian adults with renal insufficiency
    Esther M Briganti
    Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia
    Nephrology (Carlton) 10:40-7. 2005
    ..To evaluate the prevalence and treatment of cardiovascular disease and traditional cardiovascular disease risk factors in Australian adults with renal insufficiency...
  20. ncbi request reprint Association between albuminuria and proteinuria in the general population: the AusDiab Study
    Robert C Atkins
    Department of Nephrology, Monash Medical Centre, Victoria 3181, Australia
    Nephrol Dial Transplant 18:2170-4. 2003
    ..In screening for renal and cardiovascular disease, whether to measure albuminuria, proteinuria or both, is currently an unanswered question...
  21. ncbi request reprint HPLC-detected albuminuria predicts mortality
    Dianna J Magliano
    International Diabetes Institute, Melbourne, Victoria, Australia
    J Am Soc Nephrol 18:3171-6. 2007
    ..We conclude that albuminuria, detected by either IN or HPLC, independently predicts mortality in a community-based sample. HPLC identifies some people at increased risk of mortality that IN would not detect...
  22. ncbi request reprint Cardiovascular risk in dialysis patients: a comparison of risk factors and cardioprotective therapy between 1996 and 2001
    Fiona Y F Chow
    Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia
    Nephrology (Carlton) 8:177-83. 2003
    ..Proof of efficacy of these agents in this population of enormous risk is urgently required...
  23. ncbi request reprint Prevalence of kidney damage in Australian adults: The AusDiab kidney study
    Steven J Chadban
    Department of Nephrology, Monash Medical Centre, USA
    J Am Soc Nephrol 14:S131-8. 2003
    ..Identifying and targeting this section of the population may provide a means to reduce the burden of ESRD...
  24. ncbi request reprint Renal processing of serum proteins in an albumin-deficient environment: an in vivo study of glomerulonephritis in the Nagase analbuminaemic rat
    Tanya M Osicka
    Endocrine Unit, Austin and Repatriation Medical Centre, Department of Medicine, University of Melbourne, Heidelberg, Victoria, Australia
    Nephrol Dial Transplant 19:320-8. 2004
    ....
  25. ncbi request reprint Blockade of macrophage migration inhibitory factor does not prevent acute renal allograft rejection
    Matthew D Jose
    Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, Monash University, Victoria, 3168, Australia
    Am J Transplant 3:1099-106. 2003
    ..MIF blockade reduces the DTH response; however, neither local nor systemic MIF are required for the rejection of fully mismatched skin and renal allografts...
  26. ncbi request reprint Vascular access practice patterns in the New Zealand hemodialysis population
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Center, Melbourne, Victoria, Australia
    Am J Kidney Dis 43:696-704. 2004
    ..Physician practice patterns may have a strong influence on access type. We assessed differences in vascular access practice patterns across all treating centers in New Zealand...
  27. ncbi request reprint Does monthly native arteriovenous fistula blood-flow surveillance detect significant stenosis--a randomized controlled trial
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Centre, 246 Clayton Rd, Clayton, Melbourne, Victoria 3168, Australia
    Nephrol Dial Transplant 21:2498-506. 2006
    ..As these recommendations are based on observational studies, we conducted a randomized, prospective, double-blind, controlled trial to assess whether Qa surveillance results in an increased detection of AVF stenosis...
  28. ncbi request reprint Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy
    Judy B de Haan
    Centre for Functional Genomics and Human Disease, Monash Institute of Reproduction and Development, Victoria, Australia
    Am J Physiol Renal Physiol 289:F544-51. 2005
    ..Contrary to expectations, this study showed that the high level of Gpx1 expressed in the kidney is not protective against the development of renal oxidative stress and nephropathy in a model of type 1 diabetes...
  29. ncbi request reprint Induction of MIF synthesis and secretion by tubular epithelial cells: a novel action of angiotensin II
    Edwina K Rice
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Kidney Int 63:1265-75. 2003
    ..We investigated whether some of the effects of Ang II could be mediated through the production of macrophage migration inhibitory factor (MIF)...
  30. ncbi request reprint Historical controlled trial of OKT3 versus basiliximab induction therapy in simultaneous pancreas-renal transplantation
    Fiona Y F Chow
    Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia
    Nephrology (Carlton) 8:212-6. 2003
    ..Basiliximab is at least as effective and is safer than OKT3 for induction therapy in SPK transplantation...
  31. ncbi request reprint Determinants of native arteriovenous fistula blood flow
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Centre, Melbourne, Victoria 3168, Australia
    Nephrology (Carlton) 9:205-11. 2004
    ..Determinants of native arteriovenous fistula (AVF) placement have been well studied. Little is known on whether these factors impact on subsequent blood flow (Qa) in the mature AVF...
  32. ncbi request reprint Macrophages in streptozotocin-induced diabetic nephropathy: potential role in renal fibrosis
    Fiona Y Chow
    Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia
    Nephrol Dial Transplant 19:2987-96. 2004
    ....
  33. ncbi request reprint Population prevalence of albuminuria in the Australian Diabetes, Obesity, and Lifestyle (AusDiab) study: immunonephelometry compared with high-performance liquid chromatography
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Centre, Victoria, Australia
    Am J Kidney Dis 47:604-13. 2006
    ..Standard immunochemical urinary albumin assays detect immunoreactive albumin, whereas high-performance liquid chromatography (HPLC) detects both immunoreactive and immunounreactive albumin...
  34. ncbi request reprint Macrophage accumulation at a site of renal inflammation is dependent on the M-CSF/c-fms pathway
    Yannick Le Meur
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    J Leukoc Biol 72:530-7. 2002
    ..Therefore, M-CSF/c-fms signaling plays a key role in macrophage accumulation during tissue injury...
  35. ncbi request reprint The role of flow cytometric ANCA detection in screening for acute pauci-immune crescentic glomerulonephritis
    A Richard Kitching
    Centre for Inflammatory Diseases, Monash University Department of Medicine, Monash Medical Centre, Clayton, Victoria, Australia
    Nephrol Dial Transplant 19:365-70. 2004
    ..This article studied the sensitivity and specificity of serum ANCA, determined by flow cytometry and indirect immunofluorescence (IIF), to identify patients with acute PICGN...
  36. ncbi request reprint Atherosclerosis and folic acid supplementation trial in chronic renal failure: baseline results
    Sophia Zoungas
    Department of Vascular Sciences and Medicine, Monash University, Dandenong Hospital, Dandenong, Victoria, Australia
    Nephrology (Carlton) 9:130-41. 2004
    ....
  37. ncbi request reprint Arterial function after successful renal transplantation
    Sophia Zoungas
    Department of Vascular Sciences and Medicine, Monash University, Dandenong Hospital, Dandenong, Victoria, Australia
    Kidney Int 65:1882-9. 2004
    ..The aim of this study was to determine whether the increased arterial stiffness of patients with chronic renal failure is improved after successful renal transplantation...
  38. ncbi request reprint Risk factors for peritoneal dialysis-related peritonitis: can we reduce the incidence and improve patient selection?
    Despina Kotsanas
    Department of Infectious Diseases, Southern Health Monash Medical Centre, Clayton, Victoria, Australia
    Nephrology (Carlton) 12:239-45. 2007
    ..Thus, it is important to identify risk factors for PD-related peritonitis in order to reduce the incidence and improve patient selection...
  39. ncbi request reprint Activation of the ERK pathway precedes tubular proliferation in the obstructed rat kidney
    Takao Masaki
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Kidney Int 63:1256-64. 2003
    ..The aims of this study were to (1) localize ERK activation within the kidney, and (2) examine the relationship between ERK activation and cell proliferation in the injured kidney...
  40. ncbi request reprint A quarter of a century of adult peritoneal dialysis-related peritonitis at an Australian medical center
    Fiona Brown
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Perit Dial Int 27:565-74. 2007
    ..Peritonitis remains one of the major complications of peritoneal dialysis (PD) and results in reduced technique survival and increased patient morbidity and mortality...
  41. ncbi request reprint Vascular access and all-cause mortality: a propensity score analysis
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Centre, Melbourne, Victoria, Australia
    J Am Soc Nephrol 15:477-86. 2004
    ..Reducing catheter use and increasing the proportion of patients commencing hemodialysis with a mature AVF remain important clinical objectives...
  42. ncbi request reprint Health-related quality of life in Australian adults with renal insufficiency: a population-based study
    Fiona Y F Chow
    Department of Nephrology, Monash Medical Centre, Monash University, Victoria, Australia
    Am J Kidney Dis 41:596-604. 2003
    ..Although there are a large number of reports of quality of life in the setting of end-stage renal disease, the impact of lesser degrees of renal impairment in the general population has not been described...
  43. ncbi request reprint Risk of renal allograft loss from recurrent glomerulonephritis
    Esther M Briganti
    Department of Epidemiology and Preventive Medicine, Monash University, Clayton, Victoria, Australia
    N Engl J Med 347:103-9. 2002
    ..We determined the incidence, timing, and relative importance of allograft loss due to the recurrence of glomerulonephritis...
  44. ncbi request reprint Interferon-gamma augments acute macrophage-mediated renal injury via a glucocorticoid-sensitive mechanism
    Yohei Ikezumi
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    J Am Soc Nephrol 14:888-98. 2003
    ..This study provides the first evidence that it is possible to directly modulate macrophage-mediated renal injury...
  45. ncbi request reprint Blockade of macrophage colony-stimulating factor reduces macrophage proliferation and accumulation in renal allograft rejection
    Matthew D Jose
    Department of Nephrology, Monash Medical Centre, Melbourne, Australia
    Am J Transplant 3:294-300. 2003
    ..This pathway plays a significant and specific role in the accumulation of macrophages within a rejecting renal allograft...
  46. ncbi request reprint Blood pressure lowering for the prevention and treatment of diabetic kidney disease
    Merlin C Thomas
    Danielle Alberti Memorial Centre for Diabetic Complications, Wynn Domain, Baker Heart Research Institute, Melbourne, Victoria, Australia
    Drugs 66:2213-34. 2006
    ..Ultimately, no matter how it is achieved, so long as it is achieved, renal risk can be reduced by agents that lower blood pressure and albuminuria...
  47. ncbi request reprint Blockade of p38alpha MAPK ameliorates acute inflammatory renal injury in rat anti-GBM glomerulonephritis
    Cosimo Stambe
    Department of Nephrology and Monash University Department of Medicine, Monash Medical Centre, Clayton, Victoria, Australia
    J Am Soc Nephrol 14:338-51. 2003
    ..Blockade of the p38 pathway may be a novel therapeutic strategy for the treatment of acute renal inflammation...
  48. ncbi request reprint Treatment of diffuse proliferative lupus nephritis: a meta-analysis of randomized controlled trials
    Robert S Flanc
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Am J Kidney Dis 43:197-208. 2004
    ..In this systematic review of randomized controlled trials (RCTs), we assess the benefits and harm of current treatments for diffuse proliferative lupus nephritis (DPLN)...
  49. ncbi request reprint Laboratory assessment of immune function in renal transplant patients
    Paul Hutchinson
    Department of Clinical Immunology, Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia
    Nephrol Dial Transplant 18:983-9. 2003
    ..To predict this risk a score of immune competence has been developed from the simultaneous laboratory assessment of multiple parameters of immune function...
  50. ncbi request reprint Macrophage accumulation in human progressive diabetic nephropathy
    Duy Nguyen
    Department of Nephrology, Monash Medical Centre, Clayton, Australia
    Nephrology (Carlton) 11:226-31. 2006
    ..Progression to renal failure is common; however, the mechanisms are unknown. Experimental models suggest a role for macrophages. Therefore, macrophage accumulation and its relationship to the subsequent clinical course were studied...
  51. ncbi request reprint Heterogeneity of antigen expression explains controversy over glomerular macrophage accumulation in mouse glomerulonephritis
    Takao Masaki
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    Nephrol Dial Transplant 18:178-81. 2003
    ..These findings conflict with studies of human and rat glomerulonephritis. Therefore, we examined whether heterogeneity of macrophage antigen expression could explain this apparent discrepancy...
  52. ncbi request reprint Role of interleukin-10 in rat mesangioproliferative glomerulonephritis
    Tara E Robertson
    Department of Nephrology and Monash University Department of Medicine, Monash Medical Centre, Clayton, Victoria, Australia
    Nephrology (Carlton) 8:33-41. 2003
    ..However, the inability of IL-10 suppression with AS101 to prevent anti-Thy-1 disease suggests that IL-10 is not essential for pathological mesangial cell proliferation...
  53. ncbi request reprint Time and exercise improve phosphate removal in hemodialysis patients
    Indralingam Vaithilingam
    Department of Nephrology, Monash Medical Centre, Clayton, Vic, Australia
    Am J Kidney Dis 43:85-9. 2004
    ..Control of serum phosphate remains a difficult clinical issue in most hemodialysis (HD) patients. This study examines 2 nonpharmacological approaches to improving phosphate control in HD patients...
  54. ncbi request reprint Urine macrophage migration inhibitory factor reflects the severity of renal injury in human glomerulonephritis
    Fiona G Brown
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    J Am Soc Nephrol 13:S7-13. 2002
    ..Urine MIF levels reflect MIF expression within the kidney and may be a useful noninvasive tool for monitoring patients with crescentic GN, particularly in disease exacerbation...
  55. ncbi request reprint p38 Mitogen-activated protein kinase activation and cell localization in human glomerulonephritis: correlation with renal injury
    Cosimo Stambe
    Department of Nephrology and Monash University Department of Medicine, Melbourne, Australia
    J Am Soc Nephrol 15:326-36. 2004
    ..In conclusion, activation of p38 MAPK in intrinsic renal cells and infiltrating leukocytes correlated with renal dysfunction and histopathology, suggesting an important pathogenic role for p38 MAPK activation in human glomerulonephritis...
  56. ncbi request reprint Albuminuria is evident in the early stages of diabetes onset: results from the Australian Diabetes, Obesity, and Lifestyle Study (AusDiab)
    Robyn J Tapp
    International Diabetes Institute, Melbourne, Australia
    Am J Kidney Dis 44:792-8. 2004
    ..We determined the prevalence of and factors associated with albuminuria in an Australian population and examined the association of albuminuria with glucose tolerance...
  57. ncbi request reprint Ex vivo lymphocyte proliferative function is severely inhibited in renal transplant patients on mycophenolate mofetil treatment
    Paul Hutchinson
    Department of Medicine, Monash University Monash Medical Centre, 246 Clayton Road, Clayton, VIC 3168, Australia
    Transpl Immunol 13:55-61. 2004
    ..In summary we have found that MMF treatment has a strikingly inhibitory effect on patient ex vivo lymphocyte mitogenic function...
  58. ncbi request reprint Untreated hypertension among Australian adults: the 1999-2000 Australian Diabetes, Obesity and Lifestyle Study (AusDiab)
    Esther M Briganti
    Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Vic
    Med J Aust 179:135-9. 2003
    ..To measure the prevalence of untreated hypertension in Australian adults, and examine the associations with clinical and lifestyle factors...
  59. ncbi request reprint Increased incidence of benign breast disease in female renal transplant patients receiving cyclosporin
    Pornpen Sangthawan
    Department of Nephrology, Monash Medical Centre, Clayton, Victoria, Australia
    ANZ J Surg 72:222-5. 2002
    ..In order to determine the incidence of benign breast disease in renal transplant patients at Monash Medical Centre, current female patients were studied...
  60. ncbi request reprint Smoking is associated with renal impairment and proteinuria in the normal population: the AusDiab kidney study. Australian Diabetes, Obesity and Lifestyle Study
    Esther M Briganti
    Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Prahran, Victoria, Australia
    Am J Kidney Dis 40:704-12. 2002
    ..We examined the relationship between smoking and indicators of kidney damage in a healthy population without impaired fasting glucose levels, impaired glucose tolerance, diabetes mellitus, or hypertension...
  61. doi request reprint Residual proteinuria and eGFR predict progression of renal impairment within 2 years in type 2 diabetic patients with nephropathy who are receiving optimal treatment with angiotensin receptor blockers
    Sara E Ivory
    Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia
    Nephrology (Carlton) 18:516-24. 2013
    ....
  62. ncbi request reprint Native arteriovenous fistula blood flow and resistance during hemodialysis
    Kevan R Polkinghorne
    Department of Nephrology, Monash Medical Centre, Melbourne, Victoria, Australia
    Am J Kidney Dis 41:132-9. 2003
    ..Measurement of vascular access flow (Qa) has been proposed as the ideal method for surveillance of native fistulae. However, debate exists about the influence of blood pressure (mean arterial pressure [MAP]) on Qa during dialysis...
  63. ncbi request reprint Adoptive transfer studies demonstrate that macrophages can induce proteinuria and mesangial cell proliferation
    Yohei Ikezumi
    Department of Nephrology and Monash University, Clayton, Victoria, Australia
    Kidney Int 63:83-95. 2003
    ..Therefore, an adoptive transfer approach was used to directly assess the potential of macrophages to induce renal injury...
  64. doi request reprint Predictive value of nephelometric and high-performance liquid chromatography assays of urine albumin for mortality in a high-risk Aboriginal population
    Zaimin Wang
    Centre for Chronic Disease, School of Medicine, The University of Queensland, Brisbane, Australia
    Am J Kidney Dis 52:672-82. 2008
    ..We compared predictive values of albumin-creatinine ratios (ACRs) by these 2 techniques for mortality in Aboriginal people...
  65. ncbi request reprint Limited knowledge of kidney disease in a survey of AusDiab study participants
    Sarah L White
    Renal Division, The George Institute, Sydney, NSW, Australia
    Med J Aust 188:204-8. 2008
    ..To explore awareness of the causes of kidney disease and recollection of kidney function testing in a cohort of Australian adults...
  66. ncbi request reprint Leukocyte phenotype and function predicts infection risk in renal transplant recipients
    Martin Blazik
    Department of Renal Medicine, Royal Darwin Hospital, PO Box 41326, Casuarina, NT 0811, Australia
    Nephrol Dial Transplant 20:2226-30. 2005
    ..We assessed a direct measure of immune status, leukocyte phenotype and function (LPF, a composite measure of five aspects of peripheral blood leukocyte phenotype and function), as a predictor of infection...
  67. ncbi request reprint Albumin and glomerular permselectivity
    Tanya M Osicka
    Nephrol Dial Transplant 19:511-2. 2004
  68. ncbi request reprint Albuminuria and renal insufficiency prevalence guides population screening
    Esther M Briganti
    Kidney Int 64:760-1; author reply 761-2. 2003
  69. ncbi request reprint Detection and measurement of microalbuminuria: a challenge for clinical chemistry
    Douglas E Busby
    American College of Preventive Medicine, USA
    MLO Med Lab Obs 37:8-9, 12, 14-6; quiz 18-9. 2005
  70. ncbi request reprint The role of macrophages in allograft rejection
    Kate R Wyburn
    Department of Transplantation, Royal Prince Alfred Hospital and University of Sydney, Sydney, Australia
    Transplantation 80:1641-7. 2005
    ..Therapeutic attention to macrophages, in addition to T lymphocytes, may lead to improved outcomes in organ transplantation...