Shelley F Walton

Summary

Affiliation: Menzies School of Health Research
Country: Australia

Publications

  1. ncbi request reprint Acaricidal activity of Melaleuca alternifolia (tea tree) oil: in vitro sensitivity of sarcoptes scabiei var hominis to terpinen-4-ol
    Shelley F Walton
    Menzies School of Health Research, and Northern Territory Clinical School, Flinders University, Darwin, Australia
    Arch Dermatol 140:563-6. 2004
  2. doi request reprint New insights into disease pathogenesis in crusted (Norwegian) scabies: the skin immune response in crusted scabies
    S F Walton
    Tropical and Emerging Infectious Diseases Division, Menzies School of Health Research and Charles Darwin University, PO Box 41096, Casuarina, Darwin, Northern Territory 0811, Australia
    Br J Dermatol 158:1247-55. 2008
  3. pmc Problems in diagnosing scabies, a global disease in human and animal populations
    Shelley F Walton
    Menzies School of Health Research, Institute of Advanced Studies, Charles Darwin University, and Department of Medicine, Royal Darwin Hospital, Casuarina NT 0811, Australia
    Clin Microbiol Rev 20:268-79. 2007
  4. doi request reprint Scabies: molecular perspectives and therapeutic implications in the face of emerging drug resistance
    Kate E Mounsey
    Charles Darwin University, Menzies School of Health Research, Darwin, Northern Territory, Australia
    Future Microbiol 3:57-66. 2008
  5. doi request reprint A diagnostic test for scabies: IgE specificity for a recombinant allergen of Sarcoptes scabiei
    Rama Jayaraj
    Menzies School of Health Research, Darwin, Northern Territory 0810, Australia
    Diagn Microbiol Infect Dis 71:403-7. 2011
  6. ncbi request reprint Identification and characterization of Sarcoptes scabiei and Dermatophagoides pteronyssinus glutathione S-transferases: implication as a potential major allergen in crusted scabies
    Annette Dougall
    Tropical and Emerging Infectious Diseases Division, Menzies School of Health Research, Darwin, Northern Territory, Australia
    Am J Trop Med Hyg 73:977-84. 2005
  7. ncbi request reprint Identification of a homologue of a house dust mite allergen in a cDNA library from Sarcoptes scabiei var hominis and evaluation of its vaccine potential in a rabbit/S. scabiei var. canis model
    Pearly Harumal
    Menzies School of Health Research, Darwin, Northern Territory, Australia
    Am J Trop Med Hyg 68:54-60. 2003
  8. ncbi request reprint Scabies: new future for a neglected disease
    Shelley F Walton
    Menzies School of Health Research, Australia and Charles Darwin University, Darwin, Australia
    Adv Parasitol 57:309-76. 2004
  9. ncbi request reprint Molecular characterisation of a pH-gated chloride channel from Sarcoptes scabiei
    Kate E Mounsey
    Menzies School of Health Research, Institute of Advanced Studies, Charles Darwin University, Darwin, NT, Australia
    Invert Neurosci 7:149-56. 2007
  10. ncbi request reprint First documentation of in vivo and in vitro ivermectin resistance in Sarcoptes scabiei
    Bart J Currie
    Infectious Diseases Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia
    Clin Infect Dis 39:e8-12. 2004

Detail Information

Publications27

  1. ncbi request reprint Acaricidal activity of Melaleuca alternifolia (tea tree) oil: in vitro sensitivity of sarcoptes scabiei var hominis to terpinen-4-ol
    Shelley F Walton
    Menzies School of Health Research, and Northern Territory Clinical School, Flinders University, Darwin, Australia
    Arch Dermatol 140:563-6. 2004
    ..To compare the acaricidal activity of Melaleuca alternifolia (tea tree) oil (TTO) and some of its individual active components on the itch mite Sarcoptes scabiei var hominis...
  2. doi request reprint New insights into disease pathogenesis in crusted (Norwegian) scabies: the skin immune response in crusted scabies
    S F Walton
    Tropical and Emerging Infectious Diseases Division, Menzies School of Health Research and Charles Darwin University, PO Box 41096, Casuarina, Darwin, Northern Territory 0811, Australia
    Br J Dermatol 158:1247-55. 2008
    ....
  3. pmc Problems in diagnosing scabies, a global disease in human and animal populations
    Shelley F Walton
    Menzies School of Health Research, Institute of Advanced Studies, Charles Darwin University, and Department of Medicine, Royal Darwin Hospital, Casuarina NT 0811, Australia
    Clin Microbiol Rev 20:268-79. 2007
    ....
  4. doi request reprint Scabies: molecular perspectives and therapeutic implications in the face of emerging drug resistance
    Kate E Mounsey
    Charles Darwin University, Menzies School of Health Research, Darwin, Northern Territory, Australia
    Future Microbiol 3:57-66. 2008
    ..These may assist in overcoming many of the current difficulties in monitoring treatment efficacy and allow the development of more sensitive tools for monitoring emerging resistance...
  5. doi request reprint A diagnostic test for scabies: IgE specificity for a recombinant allergen of Sarcoptes scabiei
    Rama Jayaraj
    Menzies School of Health Research, Darwin, Northern Territory 0810, Australia
    Diagn Microbiol Infect Dis 71:403-7. 2011
    ..3. This study shows that quantification of levels of IgE antibody to rSar s 14.3 is a highly sensitive method for diagnosis of scabies infestation in clinical practice...
  6. ncbi request reprint Identification and characterization of Sarcoptes scabiei and Dermatophagoides pteronyssinus glutathione S-transferases: implication as a potential major allergen in crusted scabies
    Annette Dougall
    Tropical and Emerging Infectious Diseases Division, Menzies School of Health Research, Darwin, Northern Territory, Australia
    Am J Trop Med Hyg 73:977-84. 2005
    ..In addition, the specific IgE response to rSsGST01 did not correlate with the total IgE level of the patient. These results suggest that GST may play a role in the pathophysiology associated with crusted scabies...
  7. ncbi request reprint Identification of a homologue of a house dust mite allergen in a cDNA library from Sarcoptes scabiei var hominis and evaluation of its vaccine potential in a rabbit/S. scabiei var. canis model
    Pearly Harumal
    Menzies School of Health Research, Darwin, Northern Territory, Australia
    Am J Trop Med Hyg 68:54-60. 2003
    ..Although it was not found to be protective in a challenge trial, the rabbits did not exhibit typical crust characteristics. This work shows that it is now possible to conduct such challenge trials with cloned scabies antigens...
  8. ncbi request reprint Scabies: new future for a neglected disease
    Shelley F Walton
    Menzies School of Health Research, Australia and Charles Darwin University, Darwin, Australia
    Adv Parasitol 57:309-76. 2004
    ..scabiei cDNA libraries and EST projects. Ultimately this knowledge may aid early identification of disease, novel forms of chemotherapy, vaccine development and new treatment possibilities for this important but neglected parasite...
  9. ncbi request reprint Molecular characterisation of a pH-gated chloride channel from Sarcoptes scabiei
    Kate E Mounsey
    Menzies School of Health Research, Institute of Advanced Studies, Charles Darwin University, Darwin, NT, Australia
    Invert Neurosci 7:149-56. 2007
    ..These results provide the first confirmation that this group of LGIC exists in arachnids, and suggest that SsCl may be an in vivo target of ivermectin in S. scabiei...
  10. ncbi request reprint First documentation of in vivo and in vitro ivermectin resistance in Sarcoptes scabiei
    Bart J Currie
    Infectious Diseases Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia
    Clin Infect Dis 39:e8-12. 2004
    ..5 years, respectively. As predicted, ivermectin resistance in scabies mites can develop after intensive ivermectin use...
  11. pmc A novel clinical grading scale to guide the management of crusted scabies
    Joshua S Davis
    Global and Tropical Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia Department of Infectious Diseases, Royal Darwin Hospital, Darwin, Northern Territory, Australia
    PLoS Negl Trop Dis 7:e2387. 2013
    ..Here, we describe a clinical grading scale for crusted scabies and its utility in real world practice...
  12. ncbi request reprint A DNA fingerprinting system for the ectoparasite Sarcoptes scabiei
    S F Walton
    Menzies School of Health Research, Casuarina, Australia
    Mol Biochem Parasitol 85:187-96. 1997
    ....
  13. ncbi request reprint Genetic epidemiology of Sarcoptes scabiei (Acari: Sarcoptidae) in northern Australia
    S F Walton
    Queensland Institute of Medical Research, Brisbane, QLD, Australia
    Int J Parasitol 34:839-49. 2004
    ..The genetic division of dog and human derived scabies mites also has important implications in vaccine and diagnostic test development as well as the emergence and monitoring of drug resistance in S. scabiei in northern Australia...
  14. ncbi request reprint Studies in vitro on the relative efficacy of current acaricides for Sarcoptes scabiei var. hominis
    S F Walton
    Menzies School of Health Research, Darwin, Northern Territory, Australia
    Trans R Soc Trop Med Hyg 94:92-6. 2000
    ..Despite the slower killing time with 5% permethrin, there was no evidence of any mite tolerance in vivo or treatment failure in any patients or contact cases...
  15. ncbi request reprint Crusted scabies: A molecular analysis of Sarcoptes scabiei variety hominis populations from patients with repeated infestations
    S F Walton
    Menzies School of Health Research, Casuarina, Darwin, NT 0811, Australia
    Clin Infect Dis 29:1226-30. 1999
    ....
  16. ncbi request reprint Identification of ABC transporters in Sarcoptes scabiei
    K E Mounsey
    Menzies School of Health Research, Darwin NT AustraliaInstitute of Advanced Studies, Charles Darwin University, Darwin NT Australia
    Parasitology 132:883-92. 2006
    ..This work forms an important foundation for further studies to elucidate the potential role of ABC transporters in ivermectin resistance of S. scabiei...
  17. ncbi request reprint The scourge of scabies
    David J Kemp
    The Queensland Institute of Medical Research, Darwin, Australia
    Biologist (London) 49:19-24. 2002
    ..It has long been thought that dogs may act as a reservoir for human infections. However, genetic studies cast doubt over this supposition...
  18. pmc An aspartic protease of the scabies mite Sarcoptes scabiei is involved in the digestion of host skin and blood macromolecules
    Wajahat Mahmood
    Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia
    PLoS Negl Trop Dis 7:e2525. 2013
    ..We investigated whether aspartic proteases may play role in scabies mite digestive processes...
  19. ncbi request reprint Analysis of Sarcoptes scabiei finds no evidence of infection with Wolbachia
    K E Mounsey
    Menzies School of Health Research, Darwin, NT, Australia
    Int J Parasitol 35:131-5. 2005
    ..scabiei or, involved in the inflammatory disease pathogenesis of scabies unlike its activity in filarial infection...
  20. ncbi request reprint Crusted scabies: clinical and immunological findings in seventy-eight patients and a review of the literature
    L J Roberts
    Infectious Diseases Unit, Northern Territory Clinical School, Flinders University, Royal Darwin Hospital, Darwin, Northern Territory, Australia
    J Infect 50:375-81. 2005
    ..To describe the clinical and immunological features of crusted scabies in a prospectively ascertained cohort of 78 patients...
  21. doi request reprint Evidence incriminating midges (Diptera: Ceratopogonidae) as potential vectors of Leishmania in Australia
    Annette M Dougall
    Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia
    Int J Parasitol 41:571-9. 2011
    ..These findings have considerable implications in the understanding of the Leishmania life cycle worldwide...
  22. doi request reprint The immunology of susceptibility and resistance to scabies
    S F Walton
    Menzies School of Health Research and Charles Darwin University, Darwin, NT, Australia
    Parasite Immunol 32:532-40. 2010
    ..scabiei infestations in the context of earlier studies and attempt to reconcile apparent differences and emphasize those aspects of the Th1/Th2 model that are supported or refined...
  23. ncbi request reprint Circulating IgE in patients with ordinary and crusted scabies
    Larry G Arlian
    Department of Biological Sciences, Wright State University, Dayton, OH 45435 0001, USA
    J Med Entomol 41:74-7. 2004
    ..The results of this study indicate that patients with crusted scabies showed a pronounced IgE response to scabies mites, whereas patients with ordinary scabies did not...
  24. ncbi request reprint Mechanisms for a novel immune evasion strategy in the scabies mite sarcoptes scabiei: a multigene family of inactivated serine proteases
    Deborah C Holt
    Queensland Institute of Medical Research and The Australian Center for International and Tropical Health and Nutrition, Brisbane, Australia
    J Invest Dermatol 121:1419-24. 2003
    ..The identification of this family, and elucidation of its value to the parasite, may present an unanticipated approach to protective vaccination...
  25. ncbi request reprint Generation and characterization of cDNA clones from Sarcoptes scabiei var. hominis for an expressed sequence tag library: identification of homologues of house dust mite allergens
    Katja Fischer
    The Queensland Institute of Medical Research, The Australian Centre for International and Tropical Health and Nutrition, and The University of Queensland, Brisbane, Australia
    Am J Trop Med Hyg 68:61-4. 2003
    ..The availability of cDNA libraries from S. scabiei var. hominis and S. scabiei var. vulpes and the emerging public sequence databases from both opens up new possibilities in scabies research...
  26. ncbi request reprint Scabies mite inactivated serine protease paralogues are present both internally in the mite gut and externally in feces
    Charlene Willis
    Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    Am J Trop Med Hyg 75:683-7. 2006
    ..SMIPPs may well function in both of these compartments to evade host proteases...
  27. ncbi request reprint A multigene family of inactivated cysteine proteases in Sarcoptes scabiei
    Deborah C Holt
    J Invest Dermatol 123:240-1. 2004