R N Price

Summary

Affiliation: Menzies School of Health Research
Country: Australia

Publications

  1. pmc Dihydroartemisinin-piperaquine treatment of multidrug resistant falciparum and vivax malaria in pregnancy
    Jeanne Rini Poespoprodjo
    District Health Authority, Timika, Papua, Indonesia Menzies School of Health Research National Institute of Health Research and Development Research Program, Timika, Papua, Indonesia
    PLoS ONE 9:e84976. 2014
  2. pmc Highly effective therapy for maternal malaria associated with a lower risk of vertical transmission
    J R Poespoprodjo
    District Health Authority, Timika, Indonesia
    J Infect Dis 204:1613-9. 2011
  3. pmc Plasmodium vivax recurrence following falciparum and mixed species malaria: risk factors and effect of antimalarial kinetics
    Nicholas M Douglas
    Global Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia
    Clin Infect Dis 52:612-20. 2011
  4. pmc Gametocyte dynamics and the role of drugs in reducing the transmission potential of Plasmodium vivax
    Nicholas M Douglas
    Global Health Division, Menzies School of Health Research, Charles Darwin University, Darwin 0811, Australia
    J Infect Dis 208:801-12. 2013
  5. pmc Major burden of severe anemia from non-falciparum malaria species in Southern Papua: a hospital-based surveillance study
    Nicholas M Douglas
    Global Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, United Kingdom
    PLoS Med 10:e1001575; discussion e1001575. 2013
  6. pmc Review of key knowledge gaps in glucose-6-phosphate dehydrogenase deficiency detection with regard to the safe clinical deployment of 8-aminoquinoline treatment regimens: a workshop report
    Lorenz von Seidlein
    Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia
    Malar J 12:112. 2013
  7. pmc Primaquine radical cure of Plasmodium vivax: a critical review of the literature
    George K John
    Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
    Malar J 11:280. 2012
  8. doi Phenotypic and genotypic characterisation of drug-resistant Plasmodium vivax
    Ric N Price
    Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia
    Trends Parasitol 28:522-9. 2012
  9. pmc Considerations on the use of nucleic acid-based amplification for malaria parasite detection
    Stephane Proux
    Shoklo Malaria Research Unit, Mae Sot, Thailand
    Malar J 10:323. 2011
  10. pmc Trends in malaria research in 11 Asian Pacific countries: an analysis of peer-reviewed publications over two decades
    Finn Andersen
    Global Health Division, Menzies School of Health Research, Casuarina, NT 0811, Australia
    Malar J 10:131. 2011

Collaborators

  • Nicholas M Anstey
  • Qi Cheng
  • Julie A Simpson
  • Emiliana Tjitra
  • F Nosten
  • Sarah Auburn
  • Lorenz von Seidlein
  • J Kevin Baird
  • Elizabeth A Ashley
  • Jutta Marfurt
  • M D Edstein
  • Nicholas M Douglas
  • E Kenangalem
  • A Ratcliff
  • H Siswantoro
  • B Russell
  • Jeanne Rini Poespoprodjo
  • Enny Kenangalem
  • Nicholas J White
  • K A Piera
  • F Chalfein
  • B Prasetyorini
  • E P Ebsworth
  • R Suwanarusk
  • Daniel A Lampah
  • Paulus Sugiarto
  • Pratap Singhasivanon
  • George K John
  • Stephane Proux
  • J R Poespoprodjo
  • Finn Andersen
  • P Sugiarto
  • M Wuwung
  • A R Hasugian
  • R M Wuwung
  • A Brockman
  • F Laihad
  • Wendy Fobia
  • Armedy R Hasugian
  • Aung Pyae Phyo
  • Jeanne R Poespoprodjo
  • Hadjar Siswantoro
  • Bruce Russell
  • Rita Kusriastuti
  • Georges Snounou
  • Michelle S Hsiang
  • Dorina Bustos
  • Lucy Phaiphun
  • Natthapon Laochan
  • Maxine Whittaker
  • Gao Qi
  • George Taleo
  • Lily Kiricharoen
  • W Fobia
  • Julien Zwang
  • Mara Leimanis
  • A Hasanuddin
  • Marion Barends
  • Gawrie Galappaththy
  • Nick M Douglas
  • Kamini Mendis
  • Rossarin Suwanarusk
  • Michele van Vugt
  • P M Penttinen
  • F Chalfien
  • H L E Purba
  • P Prayoga
  • U Lek-Uthai
  • K Piera
  • M Chavchich
  • A Jaidee
  • M Barends
  • R Maristela

Detail Information

Publications21

  1. pmc Dihydroartemisinin-piperaquine treatment of multidrug resistant falciparum and vivax malaria in pregnancy
    Jeanne Rini Poespoprodjo
    District Health Authority, Timika, Papua, Indonesia Menzies School of Health Research National Institute of Health Research and Development Research Program, Timika, Papua, Indonesia
    PLoS ONE 9:e84976. 2014
    ..We review the exposure of pregnant women to the combination dihydroartemisinin-piperaquine over a 6 year period...
  2. pmc Highly effective therapy for maternal malaria associated with a lower risk of vertical transmission
    J R Poespoprodjo
    District Health Authority, Timika, Indonesia
    J Infect Dis 204:1613-9. 2011
    ..The epidemiology of congenital malaria was investigated in a hospital-based malaria surveillance study in Papua, Indonesia...
  3. pmc Plasmodium vivax recurrence following falciparum and mixed species malaria: risk factors and effect of antimalarial kinetics
    Nicholas M Douglas
    Global Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia
    Clin Infect Dis 52:612-20. 2011
    ..Plasmodium vivax malaria commonly follows treatment of falciparum malaria in regions of co-endemicity. This is an important cause of preventable morbidity...
  4. pmc Gametocyte dynamics and the role of drugs in reducing the transmission potential of Plasmodium vivax
    Nicholas M Douglas
    Global Health Division, Menzies School of Health Research, Charles Darwin University, Darwin 0811, Australia
    J Infect Dis 208:801-12. 2013
    ..Designing interventions that will reduce transmission of vivax malaria requires knowledge of Plasmodium vivax gametocyte dynamics...
  5. pmc Major burden of severe anemia from non-falciparum malaria species in Southern Papua: a hospital-based surveillance study
    Nicholas M Douglas
    Global Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, United Kingdom
    PLoS Med 10:e1001575; discussion e1001575. 2013
    ..The burden of anemia attributable to non-falciparum malarias in regions with Plasmodium co-endemicity is poorly documented. We compared the hematological profile of patients with and without malaria in southern Papua, Indonesia...
  6. pmc Review of key knowledge gaps in glucose-6-phosphate dehydrogenase deficiency detection with regard to the safe clinical deployment of 8-aminoquinoline treatment regimens: a workshop report
    Lorenz von Seidlein
    Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia
    Malar J 12:112. 2013
    ..The discussions and conclusions of a workshop conducted in Incheon, Korea in May 2012 to review key knowledge gaps in G6PD deficiency are reported here...
  7. pmc Primaquine radical cure of Plasmodium vivax: a critical review of the literature
    George K John
    Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
    Malar J 11:280. 2012
    ..Despite this its clinical efficacy is poorly characterized resulting in a lack of consensus over the optimal regimen for the radical cure of Plasmodium vivax...
  8. doi Phenotypic and genotypic characterisation of drug-resistant Plasmodium vivax
    Ric N Price
    Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia
    Trends Parasitol 28:522-9. 2012
    ..Genotyping and next-generation sequencing studies in P. vivax field isolates are set to transform our understanding of the molecular mechanisms of drug resistance...
  9. pmc Considerations on the use of nucleic acid-based amplification for malaria parasite detection
    Stephane Proux
    Shoklo Malaria Research Unit, Mae Sot, Thailand
    Malar J 10:323. 2011
    ..Few comparative studies are available, and none that addresses the issue of inter-laboratory variability...
  10. pmc Trends in malaria research in 11 Asian Pacific countries: an analysis of peer-reviewed publications over two decades
    Finn Andersen
    Global Health Division, Menzies School of Health Research, Casuarina, NT 0811, Australia
    Malar J 10:131. 2011
    ..The purpose of the study is to characterize trends in malaria-related literature from 1990 to 2009 in 11 Asian-Pacific countries that are committed to malaria elimination as a national goal...
  11. pmc In vitro activity of pyronaridine against multidrug-resistant Plasmodium falciparum and Plasmodium vivax
    R N Price
    Global Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia
    Antimicrob Agents Chemother 54:5146-50. 2010
    ..vivax and P. falciparum highlights the suitability of the drug as a novel partner for artemisinin-based combination therapy in regions where the two species are coendemic...
  12. pmc Two fixed-dose artemisinin combinations for drug-resistant falciparum and vivax malaria in Papua, Indonesia: an open-label randomised comparison
    A Ratcliff
    International Health Programme, Menzies School of Health Research and Charles Darwin University, Darwin, Northern Territory, Australia
    Lancet 369:757-65. 2007
    ..Our aim was to compare the safety and efficacy of dihydroartemisinin-piperaquine with that of artemether-lumefantrine in patients with uncomplicated malaria caused by multidrug-resistant P falciparum and P vivax...
  13. doi Amplification of pvmdr1 associated with multidrug-resistant Plasmodium vivax
    R Suwanarusk
    International Health Division, Menzies School of Health Research, Darwin, Australia
    J Infect Dis 198:1558-64. 2008
    ..Multidrug-resistant strains of Plasmodium vivax are emerging in Southeast Asia...
  14. pmc Clinical and pharmacological determinants of the therapeutic response to dihydroartemisinin-piperaquine for drug-resistant malaria
    R N Price
    Information Health Division, Menzies School of Health Research, Charles Darwin University, PO Box 41096, Casuarina, Darwin, NT 0811, Australia
    Antimicrob Agents Chemother 51:4090-7. 2007
    ..Lower plasma piperaquine concentrations and higher failure rates in children suggest that dose revision may be warranted in this age group...
  15. pmc Determinants of in vitro drug susceptibility testing of Plasmodium vivax
    B Russell
    International Health Program, Infectious Diseases Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia
    Antimicrob Agents Chemother 52:1040-5. 2008
    ..vivax and suggest that susceptibility to chloroquine may be associated with variable growth rates. These findings have important implications for the phenotypic and downstream genetic characterization of P. vivax...
  16. pmc Therapeutic response of multidrug-resistant Plasmodium falciparum and P. vivax to chloroquine and sulfadoxine-pyrimethamine in southern Papua, Indonesia
    A Ratcliff
    International Health Program, Menzies School of Health Research and Charles Darwin University, Darwin, NT, Australia
    Trans R Soc Trop Med Hyg 101:351-9. 2007
    ..falciparum and P. vivax exists both to first- and second-line therapies. Preliminary data indicate that amodiaquine retains superior efficacy compared with CQ for CQ-resistant P. vivax...
  17. ncbi Drug resistant falciparum malaria: clinical consequences and strategies for prevention
    R N Price
    Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford, UK
    Drug Resist Updat 4:187-96. 2001
    ..These short term measures will need to be accompanied by a longer term strategy to encourage antimalarial drug research and development...
  18. ncbi Artemisinin drugs: novel antimalarial agents
    R N Price
    Centre for Tropical Diseases, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Headington, Oxford, UK
    Expert Opin Investig Drugs 9:1815-27. 2000
    ..Artemisinin, artesunate and artemether are well-tolerated in both adults and children, with no evidence to date of serious clinical toxicity...
  19. pmc In vivo and in vitro efficacy of chloroquine against Plasmodium malariae and P. ovale in Papua, Indonesia
    H Siswantoro
    National Institute of Health Research and Development, Jakarta, Indonesia
    Antimicrob Agents Chemother 55:197-202. 2011
    ..8 nM). Chloroquine retains adequate efficacy against P. ovale and P. malariae, but its marked stage specificity of action may account for reports of delayed parasite clearance times...
  20. pmc In vivo and in vitro efficacy of amodiaquine monotherapy for treatment of infection by chloroquine-resistant Plasmodium vivax
    A R Hasugian
    National Institute of Health Research and Development, Ministry of Health, Jakarta, Indonesia
    Antimicrob Agents Chemother 53:1094-9. 2009
    ..001). Although amodiaquine results in a rapid clinical response, the risk of recurrence by day 28 is unacceptably high, reducing its suitability as an alternative treatment of infection by chloroquine-resistant P. vivax in this region...
  21. pmc Ex vivo activity of histone deacetylase inhibitors against multidrug-resistant clinical isolates of Plasmodium falciparum and P. vivax
    Jutta Marfurt
    Menzies School of Health Research, P O Box 41096, Casuarina, Darwin, NT 0811, Australia
    Antimicrob Agents Chemother 55:961-6. 2011
    ..and defining drug interaction with common antimalarial compounds are warranted to investigate the role of HDAC inhibitors in antimalarial therapy...