A Matthias

Summary

Country: Australia

Publications

  1. ncbi Echinacea alkylamides modulate induced immune responses in T-cells
    Anita Matthias
    MediHerb Research Laboratories, 3 85 Brandl Street, Eight Mile Plains, Brisbane, Queensland 4113, Australia
    Fitoterapia 79:53-8. 2008
  2. ncbi Echinacea alkamide disposition and pharmacokinetics in humans after tablet ingestion
    A Matthias
    MediHerb Research Laboratories, Room 422 Chemistry Department, The University of Queensland, Brisbane 4072, Australia
    Life Sci 77:2018-29. 2005
  3. ncbi Alkylamides from echinacea modulate induced immune responses in macrophages
    A Matthias
    MediHerb Research Laboratories, Queensland, Australia
    Immunol Invest 36:117-30. 2007
  4. ncbi Permeability studies of Kavalactones using a Caco-2 cell monolayer model
    A Matthias
    MediHerb Research Laboratories, Brisbane, Queensland, Australia
    J Clin Pharm Ther 32:233-9. 2007
  5. ncbi Cytochrome P450 enzyme-mediated degradation of Echinacea alkylamides in human liver microsomes
    A Matthias
    MediHerb Research Laboratories, Department of Chemistry, The University of Queensland, Brisbane, QLD 4072, Australia
    Chem Biol Interact 155:62-70. 2005
  6. ncbi Comparison of Echinacea alkylamide pharmacokinetics between liquid and tablet preparations
    A Matthias
    MediHerb Research Laboratories, 3 85 Brandl Street, Eight Mile Plains, Brisbane QLD 4113, Australia
    Phytomedicine 14:587-90. 2007
  7. ncbi Investigations into the antiadhesive activity of herbal extracts against Campylobacter jejuni
    K Bensch
    School of Pharmacy, Griffith University, Queensland, Australia
    Phytother Res 25:1125-32. 2011
  8. ncbi Permeability studies of alkylamides and caffeic acid conjugates from echinacea using a Caco-2 cell monolayer model
    A Matthias
    MediHerb Research Laboratories, University of Queensland, Brisbane, Australia
    J Clin Pharm Ther 29:7-13. 2004
  9. ncbi Stereoselective synthesis, natural occurrence and CB(2) receptor binding affinities of alkylamides from herbal medicines such as Echinacea sp
    N Matovic
    Chemistry, School of Molecular and Microbial Sciences, The University of Queensland, Brisbane, 4072, Australia
    Org Biomol Chem 5:169-74. 2007
  10. ncbi Investigations into the antibacterial activities of phytotherapeutics against Helicobacter pylori and Campylobacter jejuni
    C Cwikla
    School of Pharmacy, Griffith University, Gold Coast Campus, Queensland, Australia
    Phytother Res 24:649-56. 2010

Collaborators

  • K Schmidt
  • I Toth
  • R S Addison
  • Jürg Gertsch
  • R G Dickinson
  • K M Bone
  • R Lehmann
  • K Bensch
  • E Tiralongo
  • C Cwikla
  • A Chicca
  • N Matovic
  • R P Lehmann
  • L L Agnew
  • Z Guan
  • J Tiralongo
  • P Nieri
  • I Massarelli
  • E Martinotti
  • K Bone
  • S Benvenuti
  • A M Bianucci
  • B Adinolfi
  • F Pellati
  • J J DeVoss
  • Stefan Raduner
  • S P Guffogg
  • K Watson
  • G Gobe
  • S Crozier
  • Z H Endre
  • D A Willgoss
  • S W Manley

Detail Information

Publications13

  1. ncbi Echinacea alkylamides modulate induced immune responses in T-cells
    Anita Matthias
    MediHerb Research Laboratories, 3 85 Brandl Street, Eight Mile Plains, Brisbane, Queensland 4113, Australia
    Fitoterapia 79:53-8. 2008
    ....
  2. ncbi Echinacea alkamide disposition and pharmacokinetics in humans after tablet ingestion
    A Matthias
    MediHerb Research Laboratories, Room 422 Chemistry Department, The University of Queensland, Brisbane 4072, Australia
    Life Sci 77:2018-29. 2005
    ..This single dose study provides evidence that alkamides are orally available and that their pharmacokinetics are in agreement with the one dose three times daily regimen already recommended for echinacea...
  3. ncbi Alkylamides from echinacea modulate induced immune responses in macrophages
    A Matthias
    MediHerb Research Laboratories, Queensland, Australia
    Immunol Invest 36:117-30. 2007
    ..Echinacea appears to attenuate the response of macrophages to an immune stimulus and its combination of phytochemicals exhibits different pharmacological properties to one or more of the isolated major individual components...
  4. ncbi Permeability studies of Kavalactones using a Caco-2 cell monolayer model
    A Matthias
    MediHerb Research Laboratories, Brisbane, Queensland, Australia
    J Clin Pharm Ther 32:233-9. 2007
    ..To examine the bioavailability of kavalactones in vitro and the possible differences in their bioavailability because of variations in either chemical structure or the method of extraction used...
  5. ncbi Cytochrome P450 enzyme-mediated degradation of Echinacea alkylamides in human liver microsomes
    A Matthias
    MediHerb Research Laboratories, Department of Chemistry, The University of Queensland, Brisbane, QLD 4072, Australia
    Chem Biol Interact 155:62-70. 2005
    ..These findings suggest that Echinacea may effect the P450-mediated metabolism of other concurrently ingested pharmaceuticals...
  6. ncbi Comparison of Echinacea alkylamide pharmacokinetics between liquid and tablet preparations
    A Matthias
    MediHerb Research Laboratories, 3 85 Brandl Street, Eight Mile Plains, Brisbane QLD 4113, Australia
    Phytomedicine 14:587-90. 2007
    ..Furthermore, the results also indicated that the absorption site and any alkylamide loss due to digestive processes were similar in both preparations...
  7. ncbi Investigations into the antiadhesive activity of herbal extracts against Campylobacter jejuni
    K Bensch
    School of Pharmacy, Griffith University, Queensland, Australia
    Phytother Res 25:1125-32. 2011
    ..This study provides evidence for additional beneficial effects of marketed herbal medicines in gastrointestinal disorders...
  8. ncbi Permeability studies of alkylamides and caffeic acid conjugates from echinacea using a Caco-2 cell monolayer model
    A Matthias
    MediHerb Research Laboratories, University of Queensland, Brisbane, Australia
    J Clin Pharm Ther 29:7-13. 2004
    ..CONCLUSION: Alkylamides but not caffeic acid conjugates are likely to cross the intestinal barrier...
  9. ncbi Stereoselective synthesis, natural occurrence and CB(2) receptor binding affinities of alkylamides from herbal medicines such as Echinacea sp
    N Matovic
    Chemistry, School of Molecular and Microbial Sciences, The University of Queensland, Brisbane, 4072, Australia
    Org Biomol Chem 5:169-74. 2007
    ....
  10. ncbi Investigations into the antibacterial activities of phytotherapeutics against Helicobacter pylori and Campylobacter jejuni
    C Cwikla
    School of Pharmacy, Griffith University, Gold Coast Campus, Queensland, Australia
    Phytother Res 24:649-56. 2010
    ....
  11. ncbi Facilitation of renal autoregulation by angiotensin II is mediated through modulation of nitric oxide
    Z Guan
    Renal Research Centre, Department of Medicine, Royal Brisbane Hospital, Brisbane, Queensland, Australia
    Acta Physiol Scand 179:189-201. 2003
    ..We suggest that Ang II facilitates autoregulation by a tubuloglomerular feedback-dependent mechanism through AT1 receptor-mediated depletion of nitric oxide, probably by stimulating generation of superoxide...
  12. ncbi Echinacea intake induces an immune response through altered expression of leucocyte hsp70, increased white cell counts and improved erythrocyte antioxidant defences
    L L Agnew
    School of Biological, Biomedical and Molecular Sciences, University of New England, Australia
    J Clin Pharm Ther 30:363-9. 2005
    ..006) indicative of an antioxidant effect. CONCLUSION: The pilot study suggests that Echinacea may invoke an immune response through altered expression of hsp70 and increased WCC...
  13. ncbi Cytotoxic activity of polyacetylenes and polyenes isolated from roots of Echinacea pallida
    A Chicca
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, Pisa, Italy
    Br J Pharmacol 153:879-85. 2008
    ..pallida roots by bioassay-guided fractionation, were investigated and the potential bioavailability of these compounds in the extract was studied...