Research Topics

Nickolai Titov


Affiliation: Macquarie University
Country: Australia


  1. Titov N, Dear B, Staples L, Bennett Levy J, Klein B, Rapee R, et al. MindSpot Clinic: An Accessible, Efficient, and Effective Online Treatment Service for Anxiety and Depression. Psychiatr Serv. 2015;66:1043-50 pubmed publisher
    ..This model of service delivery represents an innovative method of providing accessible, low-cost, effective, and acceptable mental health services to many people who currently are not receiving care. ..
  2. Hadjistavropoulos H, Schneider L, Mehta S, Karin E, Dear B, Titov N. Preference trial of internet-delivered cognitive behaviour therapy comparing standard weekly versus optional weekly therapist support. J Anxiety Disord. 2019;63:51-60 pubmed publisher
    ..This study demonstrates the potential of optional therapist support to meet the needs and preferences of patients and to also reduce therapist costs in routine care. ..
  3. Titov N, Dear B, Johnston L, Lorian C, Zou J, Wootton B, et al. Improving adherence and clinical outcomes in self-guided internet treatment for anxiety and depression: randomised controlled trial. PLoS ONE. 2013;8:e62873 pubmed publisher
    ..Further attention to strategies that facilitate adherence, learning, and safety will help realise the potential of self-guided interventions. Australian and New Zealand Clinical Trials Registry ACTRN12610001058066. ..
  4. Schueller S, Kwasny M, Dear B, Titov N, Mohr D. Cut points on the Patient Health Questionnaire (PHQ-9) that predict response to cognitive-behavioral treatments for depression. Gen Hosp Psychiatry. 2015;37:470-5 pubmed publisher
    ..Consistent cut points were found within the included trials. These cut points may be valuable for algorithms to support clinical decision making. ..
  5. Jones T, Dean C, Hush J, Dear B, Titov N. A systematic review of the efficacy of self-management programs for increasing physical activity in community-dwelling adults with acquired brain injury (ABI). Syst Rev. 2015;4:51 pubmed publisher
    ..The efficacy of remote delivery methods also warrants further investigation. PROSPERO CRD42013006748. ..
  6. Nielssen O, Dear B, Staples L, Dear R, Ryan K, Purtell C, et al. Procedures for risk management and a review of crisis referrals from the MindSpot Clinic, a national service for the remote assessment and treatment of anxiety and depression. BMC Psychiatry. 2015;15:304 pubmed publisher
  7. Hadjistavropoulos H, Nugent M, Alberts N, Staples L, Dear B, Titov N. Transdiagnostic Internet-delivered cognitive behaviour therapy in Canada: An open trial comparing results of a specialized online clinic and nonspecialized community clinics. J Anxiety Disord. 2016;42:19-29 pubmed publisher
    ..Differences were also not found between registered providers and graduate students, or therapists trained in psychology or another discipline. The findings support the public health potential of ICBT. ..
  8. Edmonds M, Hadjistavropoulos H, Schneider L, Dear B, Titov N. Who benefits most from therapist-assisted internet-delivered cognitive behaviour therapy in clinical practice? Predictors of symptom change and dropout. J Anxiety Disord. 2018;54:24-32 pubmed publisher
    ..Symptom improvement was greater in those who were off work on disability and those without higher post-secondary education. Clinical implications are discussed. ..
  9. Hadjistavropoulos H, Schneider L, Edmonds M, Karin E, Nugent M, Dirkse D, et al. Randomized controlled trial of internet-delivered cognitive behaviour therapy comparing standard weekly versus optional weekly therapist support. J Anxiety Disord. 2017;52:15-24 pubmed publisher
    ..82; avg. reduction ?43%) at post-treatment and 3-month follow-up. Optional weekly support appears clinically effective and acceptable for many patients and may reduce costs, but safety requires monitoring given lower completion rates. ..