Research Topics
| M A RosenthalSummaryAffiliation: Ludwig Institute for Cancer Research Country: Australia Publications
| Collaborators
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Detail Information
Publications
Phase II study of combination taxol and estramustine phosphate in the treatment of recurrent glioblastoma multiformeM A Rosenthal
Department of Clinical Haematology and Medical Ontcology, Royal Melbourne Hospital, Victoria, Australia
J Neurooncol 47:59-63. 2000..The median overall survival was 12 weeks (range 3-60+ weeks). In conclusion, the combination of Taxol and EMP is well tolerated and has modest activity in the treatment of recurrent GBM...
Phase I and pharmacokinetic study of photodynamic therapy for high-grade gliomas using a novel boronated porphyrinM A Rosenthal
Centre for Developmental Cancer Therapeutics, Parkville, Australia
J Clin Oncol 19:519-24. 2001..To determine the recommended dose, toxicity profile, and pharmacokinetics of a novel boronated porphyrin (BOPP) for photodynamic therapy (PDT) of intracranial tumors...
An Australian experience with temozolomide for the treatment of recurrent high grade gliomasM T Harris
Austin and Repatriation Medical Centre, Heidelberg, Victoria, Australia
J Clin Neurosci 8:325-7. 2001..There were no episodes of febrile neutropenia and temozolomide was generally well tolerated. In conclusion, temozolomide is an active therapy in patients with recurrent high grade glioma and our results concord with published studies...
Small cell lung cancer with tracheal obstructionB H C Le
Department of Clinical Haematology and Medical Oncology, Royal Melbourne Hospital, Parkville, Victoria, Australia
Intern Med J 35:490. 2005
Five years managing metastatic non-small cell lung cancer: experience at a teaching hospitalS Wong
Department of Clinical Haematology and Medical Oncology, Royal Melbourne Hospital, Melbourne, Victoria, Australia
Intern Med J 34:458-63. 2004..Survival data and the rate of patients entered onto clinical trials are acceptable; however, further improvements can be made by the institution of multidisciplinary clinics and the education of referring clinicians...
Survival comparison between glioblastoma multiforme and other incurable cancersB Tran
Department of Medical Oncology, Royal Melbourne Hospital, Grattan Street, Parkville, Victoria 3050, Australia
J Clin Neurosci 17:417-21. 2010..Our results demonstrate that with modern treatment, GBM survival is now comparable to, if not better than, many other incurable cancers...
Staged autologous peripheral blood progenitor cell transplantation for Ewing sarcoma and rhabdomyosarcomaD S Ritchie
Department of Clinical Haematology and Medical Oncology, Royal Melbourne Hospital, Melbourne, Victoria, Australia
Intern Med J 34:431-4. 2004
Temozolomide-induced flare in high-grade gliomas: a new clinical entityM A Rosenthal
Department of Medical Oncology and Clinical Haematology, Royal Melbourne Hospital, Parkville, Victoria, Australia
Intern Med J 32:346-8. 2002..We believe this represents the novel clinical entity of temozolomide-induced tumour flare...
Imaging modalities in high-grade gliomas: pseudoprogression, recurrence, or necrosis?I Caroline
Department of Medical Oncology, Royal Melbourne Hospital, Grattan Street, Parkville, Victoria 3050, Australia
J Clin Neurosci 19:633-7. 2012..However, further prospective studies comparing the clinical utility of MRI, PET, and SPECT are needed to establish the most reliable diagnostic tool for the differentiation of PP, RN and PD in HGG...
Treatment with the novel anti-angiogenic agent PI-88 is associated with immune-mediated thrombocytopeniaM A Rosenthal
Department of Medical Oncology and Clinical Hematology, Royal Melbourne Hospital, Parkville, Victoria, Australia
Ann Oncol 13:770-6. 2002..Preclinical data demonstrates that PI-88 inhibits angiogenesis and has anti-metastatic effects. The aim of this phase I study was to determine the recommended dose and toxicity profile of PI-88...
Open-label, phase I dose-escalation study of sodium selenate, a novel activator of PP2A, in patients with castration-resistant prostate cancerN M Corcoran
Department of Surgery, Division of Urology University of Melbourne, Royal Melbourne Hospital, 5th Floor Clinical Sciences Building, Royal Parade, Parkville, Victoria 3050, Australia
Br J Cancer 103:462-8. 2010..Angiogenesis is fundamental to the progression of many solid tumours including prostate cancer. Sodium selenate is a small, water-soluble, orally bioavailable activator of PP2A phosphatase with anti-angiogenic properties...
Management of brain metastasesL C Lim
Department of Clinical Haematology and Medical Oncology, Royal Melbourne Hospital, Melbourne, Victoria, Australia
Intern Med J 34:270-8. 2004..However, controversies remain regarding post-surgery irradiation in the setting of a solitary metastasis and the role of palliative chemotherapy...
Diagnosing cancer: changing patterns of careE Lim
Department of Medical Oncology, Melbourne Comprehensive Cancer Centre, Melbourne, Victoria, Australia
Intern Med J 37:124-6. 2007..6 days, compared with a similar study 13 years ago. This emphasizes the changing role of the oncologist in current day multidisciplinary cancer care...
