Multiple comparison procedures updatedJ Ludbrook
University of Melbourne Department of Surgery, Royal Melbourne Hospital, Parkville, Victoria, Australia
Clin Exp Pharmacol Physiol 25:1032-7. 1998
..5. Despite the corrective abilities of the new step-wise MCP, investigators should try to design their experiments and analyses to test a single, global hypothesis rather than multiple ones...
Multiple inferences using confidence intervalsJ Ludbrook
Carlton North, Victoria, Australia
Clin Exp Pharmacol Physiol 27:212-5. 2000
..This can be done for differences between group means in the case of continuous variables and for odds ratios or relative risks in the case of categorical variables set out as 2 x 2 tables...
Statistics in physiology and pharmacology: a slow and erratic learning curveJ Ludbrook
Carlton North, Victoria, Australia
Clin Exp Pharmacol Physiol 28:488-92. 2001
..It follows that research groups, national grant-giving agencies and academic institutions must make provision for the proper training and subsequent employment of biostatisticians...
Statistical techniques for comparing measurers and methods of measurement: a critical reviewJohn Ludbrook
The University of Melbourne, Parkville, Victoria, Australia
Clin Exp Pharmacol Physiol 29:527-36. 2002
..Simple techniques for detecting bias in the case of ordered categorical variables are described and commended to investigators...
Interim analyses of data as they accumulate in laboratory experimentationJohn Ludbrook
Department of Surgery, The University of Melbourne, Parkville, Victoria, Australia
BMC Med Res Methodol 3:15. 2003
..But in the setting of laboratory experiments such analyses are usually conducted secretly and with no provisions for the necessary adjustments of the Type I error-rate...
Statistics in biomedical laboratory and clinical science: applications, issues and pitfallsJohn Ludbrook
Department of Surgery, The University of Melbourne, Melbourne, Australia
Med Princ Pract 17:1-13. 2008
..Finally, the educational value to investigators of interaction with a biostatistician, before, during and after a study, cannot be overemphasized...
Outlying observations and missing values: how should they be handled?John Ludbrook
Department of Surgery, The University of Melbourne, Melbourne, Victoria, Australia
Clin Exp Pharmacol Physiol 35:670-8. 2008
..If the missing values have not occurred at random, but are associated with some property of the individuals being studied, the subsequent analysis may be biased...