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Mutant alleles of small effect are primarily responsible for the loss of fitness with slow inbreeding in Drosophila melanogasterB D Latter
Faculty of Agriculture, University of Sydney, Australia
Genetics 148:1143-58. 1998..05-0.25, assuming an exponential distribution of s. A typical chromosome would be expected to carry at least 100-200 such mutant alleles contributing to the decline in competitive fitness with slow inbreeding...
