Research Topics

Genomes and Genes


Bert De Groef


Affiliation: La Trobe University
Country: Australia


  1. Raglus T, De Groef B, Rochfort S, Rawlin G, McCowan C. Bone marrow fat analysis as a diagnostic tool to document ante-mortem starvation. Vet J. 2019;243:1-7 pubmed publisher
    ..Various methods of BMF analysis are discussed, as well as factors that influence the amount of BMF. This review also discusses the limitations of BMF analysis and makes suggestions where future research should be primarily focused. ..
  2. De Groef B, Grommen S, Darras V. Forever young: Endocrinology of paedomorphosis in the Mexican axolotl (Ambystoma mexicanum). Gen Comp Endocrinol. 2018;266:194-201 pubmed publisher
    ..Other hypothalamic factors and potential pituitary inhibitors need to be investigated to identify their roles in amphibian metamorphosis and axolotl paedomorphosis. ..
  3. Juma A, Hall N, Wong J, Gasperoni J, Watanabe Y, Sahota A, et al. PLAG1 expression and target genes in the hypothalamo-pituitary system in male mice. Mol Cell Endocrinol. 2018;478:77-83 pubmed publisher
    ..We conclude that PLAG1 deficiency does not have a major impact on the reproductive control by the hypothalamo-pituitary system. ..
  4. Watanabe Y, Grommen S, De Groef B. Corticotropin-releasing hormone: Mediator of vertebrate life stage transitions?. Gen Comp Endocrinol. 2016;228:60-68 pubmed publisher
  5. Juma A, Damdimopoulou P, Grommen S, Van de Ven W, De Groef B. Emerging role of PLAG1 as a regulator of growth and reproduction. J Endocrinol. 2016;228:R45-56 pubmed publisher
    ..Here we review the current evidence for PLAG1 as a regulator of growth and fertility and discuss possible endocrine mechanisms involved. ..
  6. Noy E, Scott M, Grommen S, Robert K, De Groef B. Molecular cloning and tissue distribution of Crh and Pomc mRNA in the fat-tailed dunnart (Sminthopsis crassicaudata), an Australian marsupial. Gene. 2017;627:26-31 pubmed publisher
    ..Mature dunnart CRH is identical to CRH in human, mouse, rat and chicken. Pomc and Crh mRNA is mainly expressed in dunnart pituitary gland and brain, respectively, but both are also present in a range of peripheral tissues. ..
  7. Juma A, Grommen S, O Bryan M, O Connor A, Merriner D, Hall N, et al. PLAG1 deficiency impairs spermatogenesis and sperm motility in mice. Sci Rep. 2017;7:5317 pubmed publisher
    ..Our results demonstrate that the subfertility seen in male PLAG1-deficient mice is, at least in part, the result of significantly reduced sperm output and sperm motility. ..
  8. Watanabe Y, Grommen S, De Groef B. Thyrotropic activity of corticotropin-releasing hormone in an altricial bird species, the zebra finch (Taeniopygia guttata). Gen Comp Endocrinol. 2018;258:99-108 pubmed publisher