Research Topics
| H N KadarmideenSummaryCountry: Australia Publications
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Detail Information
Publications
FunctSNP: an R package to link SNPs to functional knowledge and dbAutoMaker: a suite of Perl scripts to build SNP databasesStephen J Goodswen
CSIRO Livestock Industries, Davies Laboratory, University Drive, Townsville, Qld 4810, Australia
BMC Bioinformatics 11:311. 2010..Although we acknowledge the importance of human research, we identify there is a need for SNP annotation tools for other organisms...
Systems biology of ovine intestinal parasite resistance: disease gene modules and biomarkersHaja N Kadarmideen
Commonwealth Scientific and Industrial Research Organisation, Livestock Industries, Davies Laboratory, PMB PO Aitkenvale, Townsville, QLD 4814, Australia
Mol Biosyst 7:235-46. 2011..This is also the first study to apply the concept of estimating breeding values of animals to expression traits and reveals 11 heritable candidate biomarkers (0.05 to 0.92) that could be used in selection of animals for GIN resistance...
Genetical systems biology in livestock: application to gonadotrophin releasing hormone and reproductionH N Kadarmideen
CSIRO Livestock Industries, JM Rendel Laboratory, Rockhampton, Australia
IET Syst Biol 2:423-41. 2008..These results will be useful for further study of mammalian reproductive biology...
Biochemical, ECF18R, and RYR1 gene polymorphisms and their associations with osteochondral diseases and production traits in pigsHaja N Kadarmideen
Institute of Animal Science, Swiss Federal Institute of Technology, ETH Zentrum, Zurich, Switzerland
Biochem Genet 46:41-53. 2008..These results should be useful in selection and for further functional genomics and proteomics investigations...
Population and systems genetics analyses of cortisol in pigs divergently selected for stressHaja N Kadarmideen
Institute of Animal Sciences, Swiss Federal Institute of Technology, ETH Zentrum, Zurich, Switzerland
Physiol Genomics 29:57-65. 2007..This is the first study to report a strong genetic basis for cortisol physiology using a systems approach...
Genetic and phenotypic parameters for conformation and yield traits in three Swiss dairy cattle breedsY de Haas
Statistical Animal Genetics Group, Institute of Animal Sciences, Swiss Federal Institute of Technology, Zurich, Switzerland
J Anim Breed Genet 124:12-9. 2007..Results indicate that conformation traits generally can be used as predictors for various purposes in dairy cattle breeding, but may require specific adaptation for each breed...
Genetic correlations between body condition scores and fertility in dairy cattle using bivariate random regression modelsY de Haas
Institute of Animal Sciences, Swiss Federal Institute of Technology ETH Zentrum, Zurich, Switzerland
J Anim Breed Genet 124:277-85. 2007..Maximum genetic gain in fertility from indirect selection on BCS should be based on measurements taken in mid lactation when the genetic variance for BCS is largest, and the genetic correlations between BCS and fertility is strongest...
Genetic parameters for functional traits in dairy cattle from daily random regression modelsB Karacaören
Statistical Animal Genetics Group, Institute of Animal Science, Swiss Federal Institute of Technology, ETH Centrum, Zurich CH 8092, Switzerland
J Dairy Sci 89:791-8. 2006..09, respectively. Daily genetic variance-covariance of many functional traits are reported for the first time and will be useful when constructing selection indexes for more than one trait based on longitudinal genetic parameters...
PCIT: an R package for weighted gene co-expression networks based on partial correlation and information theory approachesNathan S Watson-Haigh
CSIRO Livestock Industries, Queensland Bioscience Precinct, St Lucia, QLD 4067, Australia
Bioinformatics 26:411-3. 2010..AVAILABILITY AND IMPLEMENTATION: Source code and binaries freely available (under GPL-3) for download via CRAN at http://cran.r-project.org/package=PCIT, implemented in R and supported on Linux and MS Windows...
Genetics of parity-dependant production increase and its relationship with health, fertility, longevity, and conformation in swiss holsteinsT Neuenschwander
Statistical Animal Genetics Group, Institute of Animal Sciences, Swiss Federal Institute of Technology, ETH Zentrum CH-8092 Zurich, Switzerland
J Dairy Sci 88:1540-51. 2005..ProdI is a potential trait to be included in selection indices, as it has favorable genetic relationships with economically important functional traits such as health, conformation, and longevity...
Selection on multiple QTL with control of gene diversity and inbreeding for long-term benefitY Li
Institute of Animal Sciences, Swiss Federal Institute Technology ETH, Zurich, Switzerland
J Anim Breed Genet 125:320-9. 2008..Extra responses are expected to be reduced for larger population sizes...
Bayesian inference on major loci in related multigeneration selection lines of laying hensC Hagger
Breeding Biology Group, Institute of Animal Science, Swiss Federal Institute of Technology, ETH Zentrum, CH 8092 Zurich, Switzerland
Poult Sci 83:1932-9. 2004..The detection of a major locus with relatively modest effect confirmed that this type of analysis with data from selected lines was indeed powerful...
Prediction of transcription factor binding sites using genetical genomics methodsPeter von Rohr
Institute of Animal Science, ETH Zurich, Universitätsstrasse 65, CH 8092 Zurich, Switzerland
J Bioinform Comput Biol 5:773-93. 2007..In conclusion, the results of this study clearly demonstrate the usefulness of eQTL to predict transcription factor binding sites...
Genetics of osteochondral disease and its relationship with meat quality and quantity, growth, and feed conversion traits in pigsH N Kadarmideen
Statistical Animal Genetics Group, Institute of Animal Science, Swiss Federal Institute of Technology, ETH Zentrum, Zurich CH 8092, Switzerland
J Anim Sci 82:3118-27. 2004..These findings will be useful to pig industry, especially in designing breeding programs for robust pigs...
Gene-environment interactions in complex diseases: genetic models and methods for QTL mapping in multiple half-sib populationsHaja N Kadarmideen
Statistical Animal Genetics Group, Institute of Animal Science, Swiss Federal Institute of Technology, ETH Zentrum UNS D7, Universitaetstrasse 65, Zurich 8092, Switzerland
Genet Res 88:119-31. 2006..Top-down model selection is proposed in which a full test for QEI is conducted first and then the model is subsequently simplified. Methods and results will be applicable to human, plant and animal QTL mapping experiments...
Bayesian segregation analysis of milk flow in Swiss dairy cattle using Gibbs samplingHoucine Ilahi
Statistical Animal Genetics Group, Institute of Animal Sciences, Swiss Federal Institute of Technology, ETH Zentrum, Universitätsstrasse 65, 8092 Zurich, Switzerland
Genet Sel Evol 36:563-76. 2004....
Genetic parameters for body condition score and its relationship with type and production traits in Swiss HolsteinsH N Kadarmideen
Statistical Animal Genetics Group, Institute of Animal Science, Swiss Federal Institute of Technology, ETH Zentrum, Zurich CH 8092, Switzerland
J Dairy Sci 86:3685-93. 2003..12 to -0.17). These results show that selection for good body condition, body conformation, and optimal milk production is possible and their genetic associations reported here will be useful for designing Swiss breeding goals...
Investigation of major gene for milk yield, milking speed, dry matter intake, and body weight in dairy cattleBurak Karacaören
Statistical Animal Genetics Group, Institute of Animal Sciences, ETH Zurich, Universitätstrasse 65 CH 8092 Zurich, Switzerland
J Appl Genet 47:337-43. 2006..Expected Mendelian transmission probabilities and their model fits were also compared...
Arthrogryposis multiplex congenita (AMC), a hereditary disease in swine, maps to chromosome 5 by linkage analysisSem Genini
Breeding Biology, Institute of Animal Sciences, ETH-Zentrum, CH-8092 Zurich, Switzerland
Mamm Genome 15:935-41. 2004..AMC was mapped by linkage analysis to the position 92 cM, between SW152 and SW904/SW1094, which are located on SSC5 in bands q12-q23...
From genetical genomics to systems genetics: potential applications in quantitative genomics and animal breedingHaja N Kadarmideen
Statistical Animal Genetics Group, Institute of Animal Science, Swiss Federal Institute of Technology, ETH Zentrum UNS D7, Universitaetstrasse 65, CH 8092 Zurich, Switzerland
Mamm Genome 17:548-64. 2006..quot;..
Evidence of a major gene from Bayesian segregation analyses of liability to osteochondral diseases in pigsHaja N Kadarmideen
Animal Sciences Group, Wageningen University and Research Centre, 8200 AB Lelystad, The Netherlands
Genetics 171:1195-206. 2005..This is the first study to report evidence of major genes for osteochondral lesions in pigs; these results may also form a basis for underpinning the genetic inheritance of this disease in other animals as well as in humans...
