Research Topics
Species | David Wayne JohnsonSummaryCountry: Australia Publications
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Publications
A randomized controlled trial of topical exit site mupirocin application in patients with tunnelled, cuffed haemodialysis cathetersDavid Wayne Johnson
Department of Renal Medicine, Princess Alexandra Hospital, Brisbane, Australia
Nephrol Dial Transplant 17:1802-7. 2002..Whether mupirocin offers any additional protection against infection in patients with tunnelled, cuffed haemodialysis catheters has not been studied...- Obesity is associated with worsening cardiovascular risk factor profiles and proteinuria progression in renal transplant recipientsKirsten A Armstrong
Department of Nephrology, University of Queens and at Princess Alexandra Hospital, Brisbane, Australia
Am J Transplant 5:2710-8. 2005..BMI was independently associated with proteinuria progression (beta 0.01, p = 0.008) but not with changing eGFR(MDRD.) In conclusion, obesity is common in RTR and is associated with worsening CV parameters and proteinuria progression... - Evaluation of renal function - CARI guidelinesDavid W Johnson
University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland, Australia
Aust Fam Physician 36:46. 2007..This article summarises CARI guidelines on the Evaluation of renal function and is the first in a series of articles on aspects of assessment and management of patients with chronic kidney disease... 
Effect of timing of dialysis commencement on clinical outcomes of patients with planned initiation of peritoneal dialysis in the IDEAL trialDavid W Johnson
Centre for Kidney Disease Research, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
Perit Dial Int 32:595-604. 2012....
End-stage renal failure due to amyloidosis: outcomes in 490 ANZDATA registry casesWen Tang
Correspondence and offprint requests to David Johnson E mail
Nephrol Dial Transplant 28:455-61. 2013..An appreciable proportion of amyloid ESRF patients died of amyloidosis-related complications...- Renal services disaster planning: lessons learnt from the 2011 Queensland floods and North Queensland cyclone experiencesDavid W Johnson
Department of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, Queensland, Australia
Nephrology (Carlton) 18:41-6. 2013..This paper details the responses to the disasters and examines what worked and what lessons were learnt. Recommendations are made for dialysis units in relation to disaster preparedness, response and recovery... - The effect of low glucose degradation product, neutral pH versus standard peritoneal dialysis solutions on peritoneal membrane function: the balANZ trialDavid W Johnson
Department of Renal Medicine, Princess Alexandra Hospital, Brisbane, Australia
Nephrol Dial Transplant 27:4445-53. 2012..This article reports a secondary outcome analysis of the balANZ trial with respect to peritoneal membrane function... - Association of pre-transplant statin use with delayed graft function in kidney transplant recipientsJanske Reiling
Queensland Renal Transplant Service, Princess Alexandra Hospital, Brisbane, Australia
BMC Nephrol 13:111. 2012..The aim of this study was to determine the relationship between prior statin use in renal transplant recipients and the subsequent risk of delayed graft function... - Weekend compared with weekday presentations of peritoneal dialysis-associated peritonitisDavid W Johnson
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
Perit Dial Int 32:516-24. 2012..The aim of the present study was to examine the effects of weekend compared with weekday presentation on peritonitis outcomes... - The effects of biocompatible compared with standard peritoneal dialysis solutions on peritonitis microbiology, treatment, and outcomes: the balANZ trialDavid W Johnson
Department of Nephrology, University of Queensland, Brisbane, Australia
Perit Dial Int 32:497-506. 2012..The present paper reports a secondary outcome analysis of the balANZ trial with respect to peritonitis microbiology, treatment, and outcomes... - A randomized controlled trial of oral heme iron polypeptide versus oral iron supplementation for the treatment of anaemia in peritoneal dialysis patients: HEMATOCRIT trialKatherine A Barraclough
Correspondence and offprint requests to David W Johnson E mail
Nephrol Dial Transplant 27:4146-53. 2012..The reduction in serum ferritin levels and high costs associated with HIP therapy suggest that this agent is unlikely to have a significant role in iron supplementation in PD patients... - The effects of living distantly from peritoneal dialysis units on peritonitis risk, microbiology, treatment and outcomes: a multi-centre registry studyYeoungjee Cho
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
BMC Nephrol 13:41. 2012..The aim of the study was to determine whether distance between residence and peritoneal dialysis (PD) unit influenced peritonitis occurrence, microbiology, treatment and outcomes... - Effects of biocompatible versus standard fluid on peritoneal dialysis outcomesDavid W Johnson
Department of Nephrology, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane, QLD 4102, Australia
J Am Soc Nephrol 23:1097-107. 2012.... - Seasonal variation in peritoneal dialysis-associated peritonitis: a multi-centre registry studyYeoungjee Cho
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
Nephrol Dial Transplant 27:2028-36. 2012..The role of seasonal variation in peritoneal dialysis (PD)-related peritonitis has been limited to a few small single-centre studies... - Use of aminoglycosides for peritoneal dialysis-associated peritonitis does not affect residual renal functionSunil V Badve
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
Nephrol Dial Transplant 27:381-7. 2012..However, there is limited conflicting evidence that aminoglycosides may accelerate loss of residual renal function (RRF) in PD patients. The aim of this study was to study the effect of aminoglycoside use on slope of decline in RRF... - Cardiac and vascular structure and function parameters do not improve with alternate nightly home hemodialysis: an interventional cohort studyCarolyn L Van Eps
Department of Nephrology Princess Alexandra Hospital, Ipswich Rd, Brisbane, 4102, Australia
BMC Nephrol 12:51. 2011..The effect of alternate nightly home hemodialysis (NHD) on cardiovascular structure and function is not known... - Do aluminium-based phosphate binders continue to have a role in contemporary nephrology practice?David W Mudge
Department of Nephrology, University of Queensland at Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Queensland, Australia
BMC Nephrol 12:20. 2011..Limited evidence suggests that aluminium bone disease may also be on the decline in the era of aluminium removal from dialysis fluid, even with continued use of aluminium binders... - Rationale and design of the HEALTHY-CATH trial: a randomised controlled trial of Heparin versus EthAnol Lock THerapY for the prevention of Catheter Associated infecTion in Haemodialysis patientsJennifer K Broom
Department of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
BMC Nephrol 10:23. 2009..The primary aim of the study is to determine whether weekly instillation of 70% ethanol prevents CRBs compared with standard heparin saline... - Intravenous versus oral iron supplementation for correction of post-transplant anaemia in renal transplant patientsDavid W Mudge
Department of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
BMC Nephrol 10:14. 2009.... - Adiponectin is associated with cardiovascular disease in male renal transplant recipients: baseline results from the LANDMARK 2 studyMohd O Kaisar
Department of Nephrology Princess Alexandra Hospital, Brisbane, Queensland, Australia
BMC Nephrol 10:29. 2009..No data exists on the association between adiponectin and CVD in renal transplant recipients (RTR)... - Streptococcal peritonitis in Australian peritoneal dialysis patients: predictors, treatment and outcomes in 287 casesStacey O'Shea
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
BMC Nephrol 10:19. 2009..There has not been a comprehensive, multi-centre study of streptococcal peritonitis in patients on peritoneal dialysis (PD) to date... - Rationale and design of the oral HEMe iron polypeptide Against Treatment with Oral Controlled Release Iron Tablets trial for the correction of anaemia in peritoneal dialysis patients (HEMATOCRIT trial)Katherine A Barraclough
Department of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
BMC Nephrol 10:20. 2009.... - The role of 25-hydroxyvitamin D deficiency in promoting insulin resistance and inflammation in patients with chronic kidney disease: a randomised controlled trialWilliam G Petchey
Department of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
BMC Nephrol 10:41. 2009..Secondary hypotheses will test whether this is associated with decreased inflammation and bone/adipocyte-endocrine dysregulation... - Prevention of progression of kidney disease - CARI guidelinesDavid W Johnson
University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland, Australia
Aust Fam Physician 36:353. 2007..This article summarises the CARI guidelines on Prevention of progression of kidney disease: diet and miscellaneous factors. Complete CARI guideline detail is available at the web site... - Oxpentifylline versus placebo in the treatment of erythropoietin-resistant anaemia: a randomized controlled trialDavid Wayne Johnson
Australian Kidney Trials Network, School of Population Health, University of Queensland, Brisbane, Australia
BMC Nephrol 9:8. 2008..The main hypothesis of this study is that Oxpentifylline administration will effectively treat erythropoietin- or darbepoietin-resistant anaemia in chronic kidney disease patients... - Metabolic syndrome in severe chronic kidney disease: Prevalence, predictors, prognostic significance and effects of risk factor modificationDavid W Johnson
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Queensland, Australia
Nephrology (Carlton) 12:391-8. 2007..However, the prevalence, predictors, prognostic value and treatment of MS in the CKD population have not been rigorously studied... - Erythropoiesis-stimulating agent hyporesponsivenessDavid W Johnson
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Queensland, Australia
Nephrology (Carlton) 12:321-30. 2007..A practical algorithm for approaching the investigation and management of patients with ESA hyporesponsiveness is also provided... - Modification of cardiovascular risk in hemodialysis patients: an evidence-based reviewDavid W Johnson
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, QLD, Australia
Hemodial Int 11:1-14. 2007..Large, well-conducted, multicenter randomized-controlled trials in this area are urgently required... - Intravenous versus oral iron supplementation in peritoneal dialysis patientsDavid W Johnson
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Queensland, Australia
Perit Dial Int 27:S255-60. 2007..Emerging new iron therapies such as heme iron polypeptide and ferumoxytol may further enhance the tolerability, efficacy, and ease of administration of iron in PD patients... - What is the optimal fat mass in peritoneal dialysis patients?David W Johnson
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Queensland, Australia
Perit Dial Int 27:S250-4. 2007.... - Associations of dialysis modality and infectious mortality in incident dialysis patients in Australia and New ZealandDavid W Johnson
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
Am J Kidney Dis 53:290-7. 2009..The aim of the present investigation is to compare rates, types, causes, and timing of infectious death in incident peritoneal dialysis (PD) and hemodialysis (HD) patients in Australia and New Zealand... - Frequencies of hepatitis B and C infections among haemodialysis and peritoneal dialysis patients in Asia-Pacific countries: analysis of registry dataDavid W Johnson
Australia and New Zealand Dialysis and Transplant Registry, Discipline of Public Health, University of Adelaide, Adelaide, Australia
Nephrol Dial Transplant 24:1598-603. 2009..The aim of the present investigation was to evaluate the rates of hepatitis C virus (HCV) and hepatitis B virus (HBV) infections in peritoneal dialysis (PD) and haemodialysis (HD) patients in the Asia-Pacific region... - The honeypot study protocol: a randomized controlled trial of exit-site application of medihoney antibacterial wound gel for the prevention of catheter-associated infections in peritoneal dialysis patientsDavid W Johnson
Australasian Kidney Trials Network, University of Queensland, Australia
Perit Dial Int 29:303-9. 2009.... - Association of dialysis modality and cardiovascular mortality in incident dialysis patientsDavid W Johnson
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, South Australia, Australia
Clin J Am Soc Nephrol 4:1620-8. 2009..The aim of the investigation presented here was to compare the rates, causes, and timing of cardiovascular (CV) death in incident peritoneal dialysis (PD) and hemodialysis (HD) patients... - Superior survival of high transporters treated with automated versus continuous ambulatory peritoneal dialysisDavid W Johnson
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
Nephrol Dial Transplant 25:1973-9. 2010.... - Encapsulating peritoneal sclerosis: incidence, predictors, and outcomesDavid W Johnson
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, South Australia, Australia
Kidney Int 77:904-12. 2010..The risk of death is relatively low and not appreciably different from that of competing risks for mortality in matched dialysis control patients... - Rationale and design of the balANZ trial: a randomised controlled trial of low GDP, neutral pH versus standard peritoneal dialysis solution for the preservation of residual renal functionDavid W Johnson
Department of Renal Medicine, Princess Alexandra Hospital, Brisbane, Australia
BMC Nephrol 11:25. 2010..The main hypothesis of this study is that neutral pH, low glucose degradation product (GDP) peritoneal dialysis (PD) fluid better preserves residual renal function in PD patients over time compared with conventional dialysate... - Effect of dialysis modality on survival of hepatitis C-infected ESRF patientsBhadran Bose
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
Clin J Am Soc Nephrol 6:2657-61. 2011..The aim of this study was to evaluate the impact of dialysis modality on the survival of HCV-infected ESRF patients... - Recommendations for the use of icodextrin in peritoneal dialysis patientsDavid W Johnson
Princess Alexandra Hospital, Brisbane, Queensland, Australia
Nephrology (Carlton) 8:1-7. 2003..This paper reviews the available clinical evidence pertaining to the safety and efficacy of icodextrin and makes recommendations for its use in peritonal dialysis... 
Icodextrin as salvage therapy in peritoneal dialysis patients with refractory fluid overloadD W Johnson
Peritoneal Dialysis Unit, Princess Alexandra Hospital, Brisbane 4102, Australia
BMC Nephrol 2:2. 2001..The aim of this study was to evaluate the ability of icodextrin to alleviate refractory, symptomatic fluid overload and prolong technique survival in PD patients...- Chronic kidney disease--management updateDavid W Johnson
University of Queensland at Princess Alexandra Hospital, Brisbane, Queensland
Aust Fam Physician 34:915-23. 2005..A recent population study demonstrated that one in every 6 Australian adults has CKD (of which the vast majority are unaware)... - Elevated white cell count at commencement of peritoneal dialysis predicts overall and cardiac mortalityDavid Wayne Johnson
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
Kidney Int 67:738-43. 2005..The aim of the present study was to evaluate the prognostic value of WCC in patients commencing peritoneal dialysis (PD)... - Time-integrated CRP level strongly predicts PD patient outcomes--nice to know, but what should we do about it?David W Johnson
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
Perit Dial Int 25:234-7. 2005 - Randomized, controlled trial of topical exit-site application of honey (Medihoney) versus mupirocin for the prevention of catheter-associated infections in hemodialysis patientsDavid Wayne Johnson
Department of Renal Medicine, Level 2, Ambulatory Renal and Transplant Services Building, University of Queensland at Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane, Queensland 4102, Australia
J Am Soc Nephrol 16:1456-62. 2005.... - Predictors of decline of residual renal function in new peritoneal dialysis patientsDavid W Johnson
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Queensland, Australia
Perit Dial Int 23:276-83. 2003..The aim of this study was to prospectively evaluate the risk factors for decline of residual renal function (RRF) in an incident peritoneal dialysis (PD) population... - A comparison of peritoneal equilibration tests performed 1 and 4 weeks after PD commencementDavid W Johnson
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
Perit Dial Int 24:460-5. 2004.... - A peritoneal dialysis patient with fatal culture-negative peritonitisDavid W Johnson
University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland, Australia
Nephrology (Carlton) 8:49-55. 2003.... - Evidence-based guide to slowing the progression of early renal insufficiencyD W Johnson
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Queensland 4102, Australia
Intern Med J 34:50-7. 2004..The present paper reviews the available published randomised controlled clinical trials and meta-analyses supporting (or refuting) a role for each of these therapeutic manoeuvres... - The effect of obesity on renal transplant outcomesDavid W Johnson
Renal Transplant Unit, Princess Alexandra Hospital, Brisbane, Australia
Transplantation 74:675-81. 2002..The present study aimed to evaluate the effect of obesity on renal transplant outcomes in a rigorously screened population... - Oral versus intravenous iron supplementation in peritoneal dialysis patientsD W Johnson
Department of Renal Medicine, Princess Alexandra Hospital, Brisbane, Queensland, Australia
Perit Dial Int 21:S231-5. 2001..Nevertheless, a growing body of evidence suggests that, as has been found for hemodialysis patients, intravenous iron therapy is superior to oral iron supplementation in EPO-treated PD patients... - Automated reporting of GFR--coming soon to a laboratory near you!David Johnson
University of Queensland at Princess Alexandra Hospital, Brisbane, Queensland
Aust Fam Physician 34:925-31. 2005.... - Dietary protein restriction as a treatment for slowing chronic kidney disease progression: the case againstDavid W Johnson
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
Nephrology (Carlton) 11:58-62. 2006..g. renin-angiotensin system blockade, blood pressure reduction and statin therapy)... - A randomized controlled trial of coiled versus straight swan-neck Tenckhoff catheters in peritoneal dialysis patientsDavid W Johnson
Department of Renal Medicine and Renal Transplant Unit, University of Queensland at Princess Alexandra Hospital, Brisbane, QLD, Australia
Am J Kidney Dis 48:812-21. 2006..However, a recent Cochrane review recommended the need for a large, well-designed, randomized, controlled trial of straight versus coiled PD catheters because of the paucity and suboptimal quality of previously performed trials... - Novel renoprotective actions of erythropoietin: new uses for an old hormoneDavid W Johnson
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Queensland, Australia
Nephrology (Carlton) 11:306-12. 2006..Gaining further insight into the pleiotropic actions of EPO will hopefully eventuate in much-needed, novel therapeutic strategies for patients with kidney disease... - Deceased donor renal transplantation--does side matter?David W Johnson
Queensland Renal Transplant Service, University of Queensland, Princess Alexandra Hospital, Brisbane, QLD, Australia
Nephrol Dial Transplant 21:2583-8. 2006..The aim of the present study was to determine whether the deceased donor kidney side (left or right kidney) was predictive of subsequent kidney transplant outcomes... - Delayed administration of darbepoetin or erythropoietin protects against ischemic acute renal injury and failureD W Johnson
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
Kidney Int 69:1806-13. 2006..These results reaffirm the potential clinical application of DPO and EPO as novel renoprotective agents for patients at risk of ischemic acute renal failure or after having sustained an ischemic renal insult... - Obesity is associated with worse peritoneal dialysis outcomes in the Australia and New Zealand patient populationsStephen P McDonald
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
J Am Soc Nephrol 14:2894-901. 2003..Such patients should be closely monitored during PD and should be considered for early transfer to an alternative renal replacement therapy if difficulties are experienced... - Impact of obesity on renal transplant outcomesKirsten A Armstrong
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Queensland, Australia
Nephrology (Carlton) 10:405-13. 2005..It can be concluded, however, that pre- and posttransplant obesity should be targeted as aggressively as the more well-established cardiovascular risk factors in order to optimize long-term renal transplant outcomes... - Predictors of a favourable response to icodextrin in peritoneal dialysis patients with ultrafiltration failureKathryn J Wiggins
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Woolloongabba, Brisbane 4102, Queensland, Australia
Nephrology (Carlton) 10:33-6. 2005..CONCLUSION: Icodextrin significantly augments ultrafiltration volumes in patients with refractory fluid overload. A high peritoneal membrane transporter status is the best predictor of a favourable ultrafiltration response to icodextrin... - Predictors of baseline peritoneal transport status in Australian and New Zealand peritoneal dialysis patientsMarkus Rumpsfeld
Australia and New Zealand Dialysis and Transplant Association Registry, Adelaide, Australia
Am J Kidney Dis 43:492-501. 2004..The diversity of peritoneal transport characteristics in different ethnic populations suggests that additional validation of PET measurements in various racial groups and study of their relationship to patient outcomes are warranted... - Obesity is a risk factor for peritonitis in the Australian and New Zealand peritoneal dialysis patient populationsStephen P McDonald
ANZDATA Registry, Adelaide, South Australia
Perit Dial Int 24:340-6. 2004..The aim of the present investigation was to examine the association between body mass index (BMI) and peritonitis rates among incident peritoneal dialysis (PD) patients in a large cohort with long-term follow-up... - Epidemiology and outcomes of peritonitis in children on peritoneal dialysis in AustralasiaEsmeralda B Bordador
Queensland Child and Adolescent Renal Service, Royal Children s Hospital and Mater Children s Hospitals, Herston Road, 4029 Herston, Brisbane, Queensland, Australia
Pediatr Nephrol 25:1739-45. 2010..Further prospective studies are required to determine the most appropriate prophylactic measures and antibiotic regimens for use in pediatric patients... - Pseudomonas peritonitis in Australia: predictors, treatment, and outcomes in 191 casesBrian Siva
Australia and New Zealand Dialysis and Transplant Registry, University of Adelaide at Queen Elizabeth Hospital, Adelaide, South Australia, Australia
Clin J Am Soc Nephrol 4:957-64. 2009..Pseudomonas peritonitis is a serious complication of peritoneal dialysis. To date, there as been no comprehensive, multicenter study of this condition... - Polymicrobial peritonitis in peritoneal dialysis patients in Australia: predictors, treatment, and outcomesKatherine Barraclough
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
Am J Kidney Dis 55:121-31. 2010..The study aim was to examine the frequency, predictors, treatment, and clinical outcomes of peritoneal dialysis-associated polymicrobial peritonitis... - Review article: Hepatitis B and dialysisMatthew Edey
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Queensland, Australia
Nephrology (Carlton) 15:137-45. 2010..Prevention and treatment will be discussed, with a specific focus on strategies to improve vaccination response, new therapeutic options and selection of patients for therapy... - Higher rate and earlier peritonitis in Aboriginal patients compared to non-Aboriginal patients with end-stage renal failure maintained on peritoneal dialysis in Australia: analysis of ANZDATAWai H Lim
Renal Unit, Queen Elizabeth Hospital, Adelaide, South Australia, Australia
Nephrology (Carlton) 10:192-7. 2005..Peritonitis accounts for the bulk of these technique failures, but it is uncertain whether the increased risk of peritonitis in Aboriginal patients was independent of associated comorbid conditions, such as diabetes mellitus... - Effect of previously failed kidney transplantation on peritoneal dialysis outcomes in the Australian and New Zealand patient populationsSunil V Badve
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
Nephrol Dial Transplant 21:776-83. 2006..CONCLUSION: Patients commencing PD after renal allograft failure experienced outcomes comparable with those with failed native kidneys. PD appears to be a viable option for patients with failed kidney allografts... - Predictors of renal recovery in Australian and New Zealand end-stage renal failure patients treated with peritoneal dialysisAnn Maree S Craven
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
Perit Dial Int 27:184-91. 2007..The aim of this study was to investigate the factors affecting recovery and durability of dialysis-independent renal function following commencement of peritoneal dialysis (PD)... - Recovery of renal function in end-stage renal failure--comparison between peritoneal dialysis and haemodialysisJames A Macdonald
ANZDATA Registry, Adelaide, Australia
Nephrol Dial Transplant 24:2825-31. 2009..The aim of this study was to investigate the effect of dialysis modality on the likelihood, timing and durability of recovery of dialysis-independent renal function... - Does uric acid have a pathogenetic role in graft dysfunction and hypertension in renal transplant recipients?Kirsten A Armstrong
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Ipswich Road, Brisbane, Queensland 4102, Australia
Transplantation 80:1565-71. 2005..Uric acid (UA) may play a pathogenetic role in hypertension and kidney disease. We explored the prevalence of hyperuricemia and the relationship of UA to graft function and hypertension in prevalent renal transplant recipients (RTR)... - High membrane transport status on peritoneal dialysis is not associated with reduced survival following transfer to haemodialysisKathryn J Wiggins
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
Nephrol Dial Transplant 22:3005-12. 2007..In this study, we aimed to assess the impact of peritoneal membrane transporter status on patient survival and the likelihood of return to PD following transfer from PD to HD... - Silibinin--a promising new treatment for cancerCatherine Wing Ying Cheung
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Queensland, Australia
Anticancer Agents Med Chem 10:186-95. 2010..The results of these studies may help to more precisely target and dose silibinin therapy to optimise clinical outcomes for oncology patients... - Baseline and time-averaged fluid removal affect technique survival in peritoneal dialysis in a non-linear fashionKathryn J Wiggins
Department of Renal Medicine, The University of Queensland at the Princess Alexandra Hospital, Woolloongabba, Queensland, Australia
Nephrology (Carlton) 12:218-23. 2007..The longevity of peritoneal dialysis (PD) is limited by technique failure and patient mortality. The authors assessed the influence of baseline and time-averaged fluid removal on patient, technique and death-censored technique survival... - Predictors and outcomes of fungal peritonitis in peritoneal dialysis patientsRhianna Miles
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
Kidney Int 76:622-8. 2009..Our study shows that fungal peritonitis is a serious complication of peritoneal dialysis and should be strongly suspected in the context of recent antibiotic treatment for bacterial peritonitis... - Interleukin-1beta induces human proximal tubule cell injury, alpha-smooth muscle actin expression and fibronectin productionDavid A Vesey
Department of Renal Medicine, Princess Alexandra Hospital, Woolloongabba, Brisbane, Queensland 4102, Australia
Kidney Int 62:31-40. 2002..The aim of the present study, therefore, was to investigate the potentially fibrogenic mechanisms of interleukin-1beta (IL-1beta), a macrophage-derived pro-inflammatory cytokine, on human proximal tubule cells (PTC)... - Erythropoietin protects against ischaemic acute renal injuryDavid A Vesey
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
Nephrol Dial Transplant 19:348-55. 2004..The aim of the present study was to determine whether EPO administration is also renoprotective in both in vitro and in vivo models of ischaemic acute renal failure... - Cardiorespiratory fitness is independently associated with 25-hydroxyvitamin D in chronic kidney diseaseWilliam G Petchey
Department of Nephrology, Princess Alexandra Hospital, Brisbane, Queensland, Australia
Clin J Am Soc Nephrol 6:512-8. 2011.... - Proinflammatory and proliferative responses of human proximal tubule cells to PAR-2 activationDavid A Vesey
1Centre for Kidney Disease Research, University of Queensland Department of Medicine, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia
Am J Physiol Renal Physiol 293:F1441-9. 2007..In PTC cultures SLIGKV-NH2 initiates proinflammatory and proliferative responses. Trypsinogen expressed within the kidney has the potential to contribute to PAR-2 activation in certain circumstances... - Automated reporting of eGFR: a useful tool for identifying and managing kidney diseaseDavid W Johnson
Princess Alexandra Hospital, Brisbane, QLD, Australia
Med J Aust 190:200-3. 2009..Clinicians should be aware of the strengths, weaknesses and appropriate use of eGFR. Considerable research effort is being directed towards further refinement of eGFR... - Free fatty acids are associated with obesity, insulin resistance, and atherosclerosis in renal transplant recipientsKirsten A Armstrong
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Queensland, Australia
Transplantation 80:937-44. 2005..The aim of this study was to determine the prevalence of IR and the relationships between FFAs, central obesity, and atherosclerosis in a cohort of prevalent RTRs... - Intradermal versus intramuscular hepatitis B vaccination in hemodialysis patients: a prospective open-label randomized controlled trial in nonresponders to primary vaccinationKatherine A Barraclough
Department of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
Am J Kidney Dis 54:95-103. 2009..Primary hepatitis B virus (HBV) vaccination through the intramuscular (IM) route is less efficacious in dialysis patients than in the general population. Previous studies suggest improved seroconversion with intradermal (ID) vaccination... - Chronic kidney disease and automatic reporting of estimated glomerular filtration rate: revised recommendationsTimothy H Mathew
Kidney Health Australia, Adelaide, SA, Australia
Med J Aust 187:459-63. 2007..The Working Group supports the use of eGFR to assist drug dosing decision making in general practice... - Increased targeting of cardiovascular risk factors in patients with chronic kidney disease does not improve atheroma burden or cardiovascular functionNicole M Isbel
Department of Renal Medicine, Princess Alexandra Hospital, Brisbane, Australia
Am Heart J 151:745-53. 2006..We studied the efficacy of a MRFI program in CKD... - Prevention of access-related infection in dialysisKatherine A Barraclough
Department of Nephrology, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia
Expert Rev Anti Infect Ther 7:1185-200. 2009.... - The influence of obesity on the development and survival outcomes of chronic kidney diseaseKathryn J Wiggins
Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Brisbane, Queensland 4102, Australia
Adv Chronic Kidney Dis 12:49-55. 2005..Possible mechanisms underlying these observed associations will be discussed... - Role of protein kinase C and oxidative stress in interleukin-1beta-induced human proximal tubule cell injury and fibrogenesisDavid A Vesey
Department of Renal Medicine, University of Queensland at the Princess Alexandra Hospital, Brisban, Queensland, Australia
Nephrology (Carlton) 10:73-80. 2005..The anti-oxidant, NAC, appears to ameliorate part of the fibrogenic effect of IL-1beta on PTC through mechanisms that do not significantly involve protein kinase C activation or nitric oxide release... - Efficacy and side-effect profile of sevelamer hydrochloride used in combination with conventional phosphate bindersJoanna M Sturtevant
Department of Nephrology, Princess Alexandra Hospital, Brisbane, Queensland, Australia
Nephrology (Carlton) 9:406-13. 2004..However, cost limits its usefulness in many countries. Data assessing its effectiveness and safety in combination with conventional phosphate binders are lacking... - Predictors, treatment, and outcomes of non-Pseudomonas Gram-negative peritonitisElizabeth M Jarvis
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, South Australia, Australia
Kidney Int 78:408-14. 2010..Its cure with antibiotics alone is less likely when multiple organisms are involved... - Culture-negative peritonitis in peritoneal dialysis patients in Australia: predictors, treatment, and outcomes in 435 casesMagid Fahim
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
Am J Kidney Dis 55:690-7. 2010..The aim of this investigation is to examine the frequency, predictors, treatment, and outcomes of culture-negative PD-associated peritonitis... - Thrombin stimulates proinflammatory and proliferative responses in primary cultures of human proximal tubule cellsDavid A Vesey
Department of Renal Medicine, University of Queensland, Princess Alexandra Hospital, Brisbane, Queenlsand, Australia
Kidney Int 67:1315-29. 2005..The aim of this study was to investigate the proinflammatory and fibroproliferative effects of the coagulation protease thrombin on human proximal tubular cells (PTC) in culture... - Interleukin-1beta stimulates human renal fibroblast proliferation and matrix protein production by means of a transforming growth factor-beta-dependent mechanismDavid A Vesey
Department of Renal Medicine, Princess Alexandra Hospital, Brisbane, QLD, Australia
J Lab Clin Med 140:342-50. 2002..The fibrogenic and proliferative action of IL-1beta on CF appears not to involve activation of PKC or production of NO but is at least partly TGFbeta-dependent... - Potential physiological and pathophysiological roles for protease-activated receptor-2 in the kidneyDavid A Vesey
Centre for Kidney Disease Research, University of Queensland Department of Medicine, Princess Alexandra Hospital, Woolloongabba, Brisbane, Queensland, Australia
Nephrology (Carlton) 12:36-43. 2007..In this review the potential roles of PAR-2 in the kidney are highlighted and discussed... - End-stage kidney disease due to scleroderma--outcomes in 127 consecutive ANZDATA registry casesBrian Siva
ANZDATA Registry, Adelaide, Australia
Nephrol Dial Transplant 26:3165-71. 2011..Scleroderma is an uncommon cause of end-stage kidney disease (ESKD) which carries significant morbidity and mortality risks. The aim of this study was to determine the prevalence, treatment and outcomes of scleroderma patients with ESKD... - Enterococcal peritonitis in Australian peritoneal dialysis patients: predictors, treatment and outcomes in 116 casesMatthew Edey
Australia and New Zealand Dialysis and Transplant Registry, Adelaide, Australia
Nephrol Dial Transplant 25:1272-8. 2010..03). CONCLUSIONS: Enterococcal peritonitis is associated with an increased risk of catheter removal, permanent haemodialysis transfer and death, particularly when other organisms are isolated in the same episode... - Pure red cell aplasia induced by erythropoiesis-stimulating agentsCarol Pollock
Department of Medicine, Royal North Shore Hospital, University of Sydney, Department of Medicine, Pacific Highway, Street Leonards, NSW, 2065, Australia
Clin J Am Soc Nephrol 3:193-9. 2008..Continued study of epoetin-induced pure red cell aplasia is needed to help nephrologists prevent or manage future cases and will have implications for the use of other protein-based therapeutic agents...