Alan G Baxter

Summary

Affiliation: James Cook University
Country: Australia

Publications

  1. ncbi The origin and application of experimental autoimmune encephalomyelitis
    Alan G Baxter
    Comparative Genomics Centre, Molecular Sciences Building 21, James Cook University, Townsville, 4, 811, Queensland, Australia
    Nat Rev Immunol 7:904-12. 2007
  2. ncbi Genetic control of susceptibility to autoimmune gastritis
    Alan G Baxter
    Comparative Genomics Centre, James Cook University, Townsville, QLD, Australia
    Int Rev Immunol 24:55-62. 2005
  3. ncbi Congenic analysis of the NKT cell control gene Nkt2 implicates the peroxisomal protein Pxmp4
    Julie M Fletcher
    Comparative Genomics Centre, James Cook University, Townsville, Queensland, Australia
    J Immunol 181:3400-12. 2008
  4. ncbi The interleukin 1 beta (IL1B) gene is associated with failure to achieve remission and impaired emotion processing in major depression
    Bernhard T Baune
    Department of Psychiatry and Psychiatric Neuroscience, James Cook University, Queensland, Australia
    Biol Psychiatry 67:543-9. 2010
  5. ncbi Role of SLAM in NKT cell development revealed by transgenic complementation in NOD mice
    Margaret A Jordan
    Comparative Genomics Centre, James Cook University, Townsville, Queensland 4811, Australia
    J Immunol 186:3953-65. 2011
  6. ncbi Interactions between B-lymphocytes and type 1 NKT cells in autoimmune diabetes
    François D Dufour
    Comparative Genomics Centre, James Cook University, Townsville, Queensland, Australia
    J Immunotoxicol 5:249-57. 2008
  7. ncbi Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis
    Socorro Miranda-Hernandez
    Comparative Genomics Centre, James Cook University, Townsville, Queensland 4811, Australia
    J Immunol 187:791-804. 2011
  8. ncbi Slamf1, the NKT cell control gene Nkt1
    Margaret A Jordan
    Comparative Genomics Center, James Cook University, Townsville, Queensland, Australia
    J Immunol 178:1618-27. 2007
  9. ncbi Genetic control of NKT cell numbers
    Margaret A Jordan
    Comparative Genomics Centre, James Cook University, Townsville, Queensland, Australia
    Immunol Cell Biol 82:276-84. 2004
  10. ncbi Quantitative and qualitative approaches to GOD: the first 10 years of the clonal selection theory
    Margaret A Jordan
    Comparative Genomics Centre, James Cook University, Molecular Sciences Bldg 21, Townsville, Queensland, Australia
    Immunol Cell Biol 86:72-9. 2008

Collaborators

Detail Information

Publications18

  1. ncbi The origin and application of experimental autoimmune encephalomyelitis
    Alan G Baxter
    Comparative Genomics Centre, Molecular Sciences Building 21, James Cook University, Townsville, 4, 811, Queensland, Australia
    Nat Rev Immunol 7:904-12. 2007
    ....
  2. ncbi Genetic control of susceptibility to autoimmune gastritis
    Alan G Baxter
    Comparative Genomics Centre, James Cook University, Townsville, QLD, Australia
    Int Rev Immunol 24:55-62. 2005
    ....
  3. ncbi Congenic analysis of the NKT cell control gene Nkt2 implicates the peroxisomal protein Pxmp4
    Julie M Fletcher
    Comparative Genomics Centre, James Cook University, Townsville, Queensland, Australia
    J Immunol 181:3400-12. 2008
    ..These findings raise the possibility that peroxisomes play a role in modulating glycolipid availability for CD1d presentation, thereby influencing NKT cell function...
  4. ncbi The interleukin 1 beta (IL1B) gene is associated with failure to achieve remission and impaired emotion processing in major depression
    Bernhard T Baune
    Department of Psychiatry and Psychiatric Neuroscience, James Cook University, Queensland, Australia
    Biol Psychiatry 67:543-9. 2010
    ..This study investigated the association between genetic variants of the interleukin 1 beta (IL1B) gene and amygdala and ACC responsiveness to emotional stimuli and response to antidepressant treatment...
  5. ncbi Role of SLAM in NKT cell development revealed by transgenic complementation in NOD mice
    Margaret A Jordan
    Comparative Genomics Centre, James Cook University, Townsville, Queensland 4811, Australia
    J Immunol 186:3953-65. 2011
    ..These data confirm a role for SLAM in controlling NKT cell development and are consistent with a role in both positive and negative thymic selection of NKT cells...
  6. ncbi Interactions between B-lymphocytes and type 1 NKT cells in autoimmune diabetes
    François D Dufour
    Comparative Genomics Centre, James Cook University, Townsville, Queensland, Australia
    J Immunotoxicol 5:249-57. 2008
    ..This review will analyze current knowledge on the roles of B-lymphocytes and Type 1 NKT cells in the onset of Type 1 Diabetes and explore possible outcomes of their interactions in relation to disease...
  7. ncbi Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis
    Socorro Miranda-Hernandez
    Comparative Genomics Centre, James Cook University, Townsville, Queensland 4811, Australia
    J Immunol 187:791-804. 2011
    ..These results provide a potential molecular mechanism for the observed effects of TLR signaling on the severity of autoimmune CNS inflammation...
  8. ncbi Slamf1, the NKT cell control gene Nkt1
    Margaret A Jordan
    Comparative Genomics Center, James Cook University, Townsville, Queensland, Australia
    J Immunol 178:1618-27. 2007
    ....
  9. ncbi Genetic control of NKT cell numbers
    Margaret A Jordan
    Comparative Genomics Centre, James Cook University, Townsville, Queensland, Australia
    Immunol Cell Biol 82:276-84. 2004
    ..Of great interest is a third locus on chromosome 18, identified in a novel congenic line, which can confer an absolute deficiency in this important immunoregulatory lymphocyte population...
  10. ncbi Quantitative and qualitative approaches to GOD: the first 10 years of the clonal selection theory
    Margaret A Jordan
    Comparative Genomics Centre, James Cook University, Molecular Sciences Bldg 21, Townsville, Queensland, Australia
    Immunol Cell Biol 86:72-9. 2008
    ..This methodological difference between the two men, and the mechanistic difference between their models, is key to the understanding of the clonal selection theory, its later acceptance and the proportion of credit paid to Burnet...
  11. ncbi The genetics of immunoregulatory T cells
    Margaret A Jordan
    James Cook University, Townsville, 4811, Queensland, Australia
    J Autoimmun 31:237-44. 2008
    ....
  12. ncbi Allelic Variation of Ets1 Does Not Contribute to NK and NKT Cell Deficiencies in Type 1 Diabetes Susceptible NOD Mice
    Margaret A Jordan
    Comparative Genomics Centre, Molecular Sciences Bldg 21, James Cook University, Townsville, Qld 4811, Australia
    Rev Diabet Stud 6:104-16. 2009
    ..It remains possible that a third factor not linked to the Ets1 locus controls both ETS1 expression and subsequently NK and NKT cell phenotypes...
  13. ncbi Two genetic loci independently confer susceptibility to autoimmune gastritis
    Desmond K Y Ang
    Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Melbourne, VIC 3010, Australia
    Int Immunol 19:1135-44. 2007
    ..This reduction was not significant compared with the reduction observed in BALB.B6 congenic mice, suggesting a difference in the genetic aetiology of autoimmune gastritis in NOD and BALB mice...
  14. ncbi Immunopathogenesis, loss of T cell tolerance and genetics of autoimmune gastritis
    Ian R van Driel
    The Russell Grimwade School of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Victoria 3010, Australia
    Autoimmun Rev 1:290-7. 2002
    ..The highlights of these recent advances are the subject of this review...
  15. ncbi Genetic control of NKT cell numbers maps to major diabetes and lupus loci
    Luis M Esteban
    Department of Microbiology and Immunology, University of Melbourne, Victoria, Australia
    J Immunol 171:2873-8. 2003
    ..The second most significant locus (Nkt2) mapped to the same region as Idd13, a NOD-derived diabetes susceptibility gene on chromosome 2...
  16. ncbi Mycobacteria, an environmental enhancer of lupus nephritis in a mouse model of systemic lupus erythematosus
    Christine G Hawke
    Autoimmunity Research Group, Centenary Institute of Cancer Medicine and Cell Biology, Newtown NSW, Australia
    Immunology 108:70-8. 2003
    ..The development of spontaneous mixed isotype IC in the glomeruli of some senescent NOD mice suggests that mycobacterial exposure is accelerating, rather than inducing, the development of GN in this model...
  17. ncbi Activation rules: the two-signal theories of immune activation
    Alan G Baxter
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, New South Wales, Australia
    Nat Rev Immunol 2:439-46. 2002
    ..We also propose that more-rigorous quantitative methods are required to sustain theoretical development in the future...
  18. ncbi The role of NK cells in autoimmune disease
    Alan G Baxter
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, NSW, Australia
    Autoimmunity 35:1-14. 2002
    ..In each case, we present the evidence for an association between disease and deficiencies in NK cells. The prospect of clinical interventions that stimulate NK cell activity are discussed and the current status described...