Sankar SubramanianSummaryAffiliation: Griffith University Country: Australia Publications
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Publications
Quantifying harmful mutations in human populationsSankar Subramanian
Environmental Futures Centre and Australian Rivers Institute, School of Environment, Griffith University, Nathan, QLD, Australia
Eur J Hum Genet 20:1320-2. 2012..These results could be useful for genome-wide association studies in understanding the relative contributions of rare and common variants in causing human genetic diseases...
Significance of population size on the fixation of nonsynonymous mutations in genes under varying levels of selection pressureSankar Subramanian
Environmental Futures Centre, Griffith University, Nathan, QLD 4111, Australia
Genetics 193:995-1002. 2013....
The abundance of deleterious polymorphisms in humansSankar Subramanian
Australian Rivers Institute, Griffith School of Environment, Griffith University, Nathan, Queensland 4111, Australia
Genetics 190:1579-83. 2012..This study reveals that up to 48% of nSNPs specific to a single genome are deleterious in nature, which underscores the abundance of deleterious polymorphisms in humans...
Next generation sequencing and analysis of a conserved transcriptome of New Zealand's kiwiSankar Subramanian
Griffith School of Environment and the School of Biomolecular and Physical Sciences, Griffith University, 170 Kessels Road, Nathan, QLD 4111 Australia
BMC Evol Biol 10:387. 2010..We then assembled the conserved protein-coding regions using the chicken proteome as a scaffold...
Temporal trails of natural selection in human mitogenomesSankar Subramanian
Allan Wilson Centre for Molecular Ecology and Evolution, Institute of Molecular Biosciences, Massey University, Auckland, New Zealand
Mol Biol Evol 26:715-7. 2009....
Fixation of deleterious mutations at critical positions in human proteinsSankar Subramanian
Griffith School of Environment, Griffith University, Nathan, Queensland, Australia
Mol Biol Evol 28:2687-93. 2011....
Rapid molecular evolution in a living fossilJennifer M Hay
Allan Wilson Centre for Molecular Ecology and Evolution, Institute of Molecular Biosciences, Massey University, Auckland, New Zealand
Trends Genet 24:106-9. 2008..Our work also suggests that rates of neutral molecular and phenotypic evolution are decoupled...
Nearly neutrality and the evolution of codon usage bias in eukaryotic genomesSankar Subramanian
Allan Wilson Centre for Molecular Ecology and Evolution, Institute of Molecular Biosciences, Massey University, Auckland, 0632, New Zealand
Genetics 178:2429-32. 2008..The relevance of these results to the nearly neutral theory of molecular evolution is discussed...
High mitogenomic evolutionary rates and time dependencySankar Subramanian
Griffith School of Environment, Griffith University, 170 Kessels Road, Nathan, QLD 4111, Australia
Trends Genet 25:482-6. 2009..The time-independent neutral evolutionary rates reported here would be useful for the study of recent evolutionary events...
