Sankar Subramanian

Summary

Affiliation: Griffith University
Country: Australia

Publications

  1. pmc Quantifying harmful mutations in human populations
    Sankar Subramanian
    Environmental Futures Centre and Australian Rivers Institute, School of Environment, Griffith University, Nathan, QLD, Australia
    Eur J Hum Genet 20:1320-2. 2012
  2. pmc Significance of population size on the fixation of nonsynonymous mutations in genes under varying levels of selection pressure
    Sankar Subramanian
    Environmental Futures Centre, Griffith University, Nathan, QLD 4111, Australia
    Genetics 193:995-1002. 2013
  3. pmc The abundance of deleterious polymorphisms in humans
    Sankar Subramanian
    Australian Rivers Institute, Griffith School of Environment, Griffith University, Nathan, Queensland 4111, Australia
    Genetics 190:1579-83. 2012
  4. pmc Next generation sequencing and analysis of a conserved transcriptome of New Zealand's kiwi
    Sankar Subramanian
    Griffith School of Environment and the School of Biomolecular and Physical Sciences, Griffith University, 170 Kessels Road, Nathan, QLD 4111 Australia
    BMC Evol Biol 10:387. 2010
  5. doi request reprint Temporal trails of natural selection in human mitogenomes
    Sankar Subramanian
    Allan Wilson Centre for Molecular Ecology and Evolution, Institute of Molecular Biosciences, Massey University, Auckland, New Zealand
    Mol Biol Evol 26:715-7. 2009
  6. doi request reprint Fixation of deleterious mutations at critical positions in human proteins
    Sankar Subramanian
    Griffith School of Environment, Griffith University, Nathan, Queensland, Australia
    Mol Biol Evol 28:2687-93. 2011
  7. doi request reprint Rapid molecular evolution in a living fossil
    Jennifer M Hay
    Allan Wilson Centre for Molecular Ecology and Evolution, Institute of Molecular Biosciences, Massey University, Auckland, New Zealand
    Trends Genet 24:106-9. 2008
  8. pmc Nearly neutrality and the evolution of codon usage bias in eukaryotic genomes
    Sankar Subramanian
    Allan Wilson Centre for Molecular Ecology and Evolution, Institute of Molecular Biosciences, Massey University, Auckland, 0632, New Zealand
    Genetics 178:2429-32. 2008
  9. doi request reprint High mitogenomic evolutionary rates and time dependency
    Sankar Subramanian
    Griffith School of Environment, Griffith University, 170 Kessels Road, Nathan, QLD 4111, Australia
    Trends Genet 25:482-6. 2009

Collaborators

  • Dee R Denver
  • Jennifer M Hay
  • Elmira Mohandesan
  • David M Lambert
  • Craig D Millar

Detail Information

Publications9

  1. pmc Quantifying harmful mutations in human populations
    Sankar Subramanian
    Environmental Futures Centre and Australian Rivers Institute, School of Environment, Griffith University, Nathan, QLD, Australia
    Eur J Hum Genet 20:1320-2. 2012
    ..These results could be useful for genome-wide association studies in understanding the relative contributions of rare and common variants in causing human genetic diseases...
  2. pmc Significance of population size on the fixation of nonsynonymous mutations in genes under varying levels of selection pressure
    Sankar Subramanian
    Environmental Futures Centre, Griffith University, Nathan, QLD 4111, Australia
    Genetics 193:995-1002. 2013
    ....
  3. pmc The abundance of deleterious polymorphisms in humans
    Sankar Subramanian
    Australian Rivers Institute, Griffith School of Environment, Griffith University, Nathan, Queensland 4111, Australia
    Genetics 190:1579-83. 2012
    ..This study reveals that up to 48% of nSNPs specific to a single genome are deleterious in nature, which underscores the abundance of deleterious polymorphisms in humans...
  4. pmc Next generation sequencing and analysis of a conserved transcriptome of New Zealand's kiwi
    Sankar Subramanian
    Griffith School of Environment and the School of Biomolecular and Physical Sciences, Griffith University, 170 Kessels Road, Nathan, QLD 4111 Australia
    BMC Evol Biol 10:387. 2010
    ..We then assembled the conserved protein-coding regions using the chicken proteome as a scaffold...
  5. doi request reprint Temporal trails of natural selection in human mitogenomes
    Sankar Subramanian
    Allan Wilson Centre for Molecular Ecology and Evolution, Institute of Molecular Biosciences, Massey University, Auckland, New Zealand
    Mol Biol Evol 26:715-7. 2009
    ....
  6. doi request reprint Fixation of deleterious mutations at critical positions in human proteins
    Sankar Subramanian
    Griffith School of Environment, Griffith University, Nathan, Queensland, Australia
    Mol Biol Evol 28:2687-93. 2011
    ....
  7. doi request reprint Rapid molecular evolution in a living fossil
    Jennifer M Hay
    Allan Wilson Centre for Molecular Ecology and Evolution, Institute of Molecular Biosciences, Massey University, Auckland, New Zealand
    Trends Genet 24:106-9. 2008
    ..Our work also suggests that rates of neutral molecular and phenotypic evolution are decoupled...
  8. pmc Nearly neutrality and the evolution of codon usage bias in eukaryotic genomes
    Sankar Subramanian
    Allan Wilson Centre for Molecular Ecology and Evolution, Institute of Molecular Biosciences, Massey University, Auckland, 0632, New Zealand
    Genetics 178:2429-32. 2008
    ..The relevance of these results to the nearly neutral theory of molecular evolution is discussed...
  9. doi request reprint High mitogenomic evolutionary rates and time dependency
    Sankar Subramanian
    Griffith School of Environment, Griffith University, 170 Kessels Road, Nathan, QLD 4111, Australia
    Trends Genet 25:482-6. 2009
    ..The time-independent neutral evolutionary rates reported here would be useful for the study of recent evolutionary events...