Nigel Turner

Summary

Affiliation: Garvan Institute of Medical Research
Country: Australia

Publications

  1. ncbi request reprint Limits to physical performance and metabolism across species
    Nigel Turner
    Diabetes and Obesity Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW 2010, Australia
    Curr Opin Clin Nutr Metab Care 9:691-6. 2006
  2. ncbi request reprint Scaling of Na+,K+-ATPase molecular activity and membrane fatty acid composition in mammalian and avian hearts
    Nigel Turner
    Department of Biomedical Science, Metabolic Research Centre, University of Wollongong, New South Wales, Australia
    Physiol Biochem Zool 79:522-33. 2006
  3. ncbi request reprint Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents
    Nigel Turner
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia
    Diabetes 56:2085-92. 2007
  4. doi request reprint Is mitochondrial dysfunction a cause of insulin resistance?
    Nigel Turner
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW 2010, Australia
    Trends Endocrinol Metab 19:324-30. 2008
  5. pmc Enhancement of muscle mitochondrial oxidative capacity and alterations in insulin action are lipid species dependent: potent tissue-specific effects of medium-chain fatty acids
    Nigel Turner
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia
    Diabetes 58:2547-54. 2009
  6. ncbi request reprint An allometric comparison of microsomal membrane lipid composition and sodium pump molecular activity in the brain of mammals and birds
    Nigel Turner
    Metabolic Research Centre, Department of Biomedical Science, University of Wollongong, Wollongong, NSW 2522, Australia
    J Exp Biol 208:371-81. 2005
  7. pmc Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation
    Andrew J Hoy
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, University of New South Wales, Sydney, New South Wales, Australia
    Am J Physiol Endocrinol Metab 297:E67-75. 2009
  8. ncbi request reprint Relationship between body size, Na+-K+-ATPase activity, and membrane lipid composition in mammal and bird kidney
    Nigel Turner
    Metabolic Research Centre, Department of Biomedical Science, University of Wollongong, Wollongong, New South Wales 2522, Australia
    Am J Physiol Regul Integr Comp Physiol 288:R301-10. 2005
  9. ncbi request reprint Glucose infusion causes insulin resistance in skeletal muscle of rats without changes in Akt and AS160 phosphorylation
    Andrew J Hoy
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia
    Am J Physiol Endocrinol Metab 293:E1358-64. 2007
  10. pmc PPARδ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle
    Ji Ming Ye
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, University of New South Wales, Sydney, NSW, Australia
    Br J Pharmacol 163:556-66. 2011

Collaborators

Detail Information

Publications54

  1. ncbi request reprint Limits to physical performance and metabolism across species
    Nigel Turner
    Diabetes and Obesity Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW 2010, Australia
    Curr Opin Clin Nutr Metab Care 9:691-6. 2006
    ..The factors that determine each type of metabolic rate are not the same; however, all levels of energy expenditure are strongly linked with body size...
  2. ncbi request reprint Scaling of Na+,K+-ATPase molecular activity and membrane fatty acid composition in mammalian and avian hearts
    Nigel Turner
    Department of Biomedical Science, Metabolic Research Centre, University of Wollongong, New South Wales, Australia
    Physiol Biochem Zool 79:522-33. 2006
    ....
  3. ncbi request reprint Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents
    Nigel Turner
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia
    Diabetes 56:2085-92. 2007
    ..These findings suggest that high lipid availability does not lead to intramuscular lipid accumulation and insulin resistance in rodents by decreasing muscle mitochondrial fatty acid oxidative capacity...
  4. doi request reprint Is mitochondrial dysfunction a cause of insulin resistance?
    Nigel Turner
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW 2010, Australia
    Trends Endocrinol Metab 19:324-30. 2008
    ....
  5. pmc Enhancement of muscle mitochondrial oxidative capacity and alterations in insulin action are lipid species dependent: potent tissue-specific effects of medium-chain fatty acids
    Nigel Turner
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia
    Diabetes 58:2547-54. 2009
    ..Here, we examined the tissue-specific effects of MCFAs on lipid metabolism and insulin action...
  6. ncbi request reprint An allometric comparison of microsomal membrane lipid composition and sodium pump molecular activity in the brain of mammals and birds
    Nigel Turner
    Metabolic Research Centre, Department of Biomedical Science, University of Wollongong, Wollongong, NSW 2522, Australia
    J Exp Biol 208:371-81. 2005
    ..Bird membranes also contained a relatively large percentage of 22:5 (n-6) as well as high levels of cholesterol. These results are discussed in relation to neurological function and the emerging field of membrane lipid rafts...
  7. pmc Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation
    Andrew J Hoy
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, University of New South Wales, Sydney, New South Wales, Australia
    Am J Physiol Endocrinol Metab 297:E67-75. 2009
    ....
  8. ncbi request reprint Relationship between body size, Na+-K+-ATPase activity, and membrane lipid composition in mammal and bird kidney
    Nigel Turner
    Metabolic Research Centre, Department of Biomedical Science, University of Wollongong, Wollongong, New South Wales 2522, Australia
    Am J Physiol Regul Integr Comp Physiol 288:R301-10. 2005
    ..These relationships are discussed with respect to the metabolic intensity of different-sized animals...
  9. ncbi request reprint Glucose infusion causes insulin resistance in skeletal muscle of rats without changes in Akt and AS160 phosphorylation
    Andrew J Hoy
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia
    Am J Physiol Endocrinol Metab 293:E1358-64. 2007
    ..001). These results suggest that the reduced muscle glucose uptake in rats after 5 h of acute hyperglycemia is due more to the metabolic effects of excess glycogen storage than to a defect in insulin signaling or glucose transport...
  10. pmc PPARδ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle
    Ji Ming Ye
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, University of New South Wales, Sydney, NSW, Australia
    Br J Pharmacol 163:556-66. 2011
    ..The present study aimed to characterize the effects of PPARδ agonists during insulin resistance of the whole body, muscle and liver...
  11. pmc Activation of AMPK by bitter melon triterpenoids involves CaMKKβ
    Tristan J Iseli
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Sydney, Australia
    PLoS ONE 8:e62309. 2013
    ..We therefore propose that CaMKKβ is a key upstream kinase for BMT-induced activation of AMPK...
  12. pmc Overexpression of manganese superoxide dismutase ameliorates high-fat diet-induced insulin resistance in rat skeletal muscle
    Michael J Boden
    Diabetes and Obesity Program, Garvan Institute for Medical Research, Darlinghurst, NSW, Australia 2010
    Am J Physiol Endocrinol Metab 303:E798-805. 2012
    ..05), suggesting that this effect was mediated through an altered redox state. Thus interventions causing elevation of mitochondrial antioxidant activity may offer protection against diet-induced insulin resistance in skeletal muscle...
  13. pmc Insulin resistance is a cellular antioxidant defense mechanism
    Kyle L Hoehn
    Diabetes and Obesity Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW 2010, Australia
    Proc Natl Acad Sci U S A 106:17787-92. 2009
    ..These data place mitochondrial superoxide at the nexus between intracellular metabolism and the control of insulin action potentially defining this as a metabolic sensor of energy excess...
  14. ncbi request reprint Overexpression of carnitine palmitoyltransferase I in skeletal muscle in vivo increases fatty acid oxidation and reduces triacylglycerol esterification
    Clinton R Bruce
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst
    Am J Physiol Endocrinol Metab 292:E1231-7. 2007
    ..05). These studies demonstrate that acute overexpression of CPT I in muscle leads to a repartitioning of FAs away from esterification and toward oxidation and highlight the importance of CPT I in regulating muscle FA metabolism...
  15. doi request reprint Alpha-actinin-3 deficiency results in reduced glycogen phosphorylase activity and altered calcium handling in skeletal muscle
    Kate G R Quinlan
    Institute for Neuroscience and Muscle Research, The Children s Hospital at Westmead, Sydney, NSW, Australia
    Hum Mol Genet 19:1335-46. 2010
    ..We propose that the alteration in GPh activity in the absence of alpha-actinin-3 is a fundamental mechanistic link in the association between ACTN3 genotype and human performance...
  16. ncbi request reprint Markers of mitochondrial biogenesis and metabolism are lower in overweight and obese insulin-resistant subjects
    Leonie K Heilbronn
    Diabetes and Obesity Research Program, Garvan Institute for Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia
    J Clin Endocrinol Metab 92:1467-73. 2007
    ..Impaired mitochondrial function in skeletal muscle is implicated in the development of insulin resistance. However, potential differences in fatness and fitness may influence previous results...
  17. ncbi request reprint Exercise alters the profile of phospholipid molecular species in rat skeletal muscle
    Todd W Mitchell
    Metabolic Research Centre, University of Wollongong, Wollongong, New South Wales 2522
    J Appl Physiol (1985) 97:1823-9. 2004
    ..Even though little is known about the physiological or pathophysiological role of specific phospholipid molecular species in skeletal muscle, it is likely that this remodeling will have an impact on a range of cellular functions...
  18. doi request reprint Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action
    Nigel Turner
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, New South Wales 2010, Australia
    Diabetes 57:1414-8. 2008
    ..We investigated the mechanism of activation of AMPK by BBR and explored whether derivatization of BBR could improve its in vivo efficacy...
  19. pmc Overfeeding reduces insulin sensitivity and increases oxidative stress, without altering markers of mitochondrial content and function in humans
    Dorit Samocha-Bonet
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Darlinghurst, Australia
    PLoS ONE 7:e36320. 2012
    ..High fat feeding induces insulin resistance and increases skeletal muscle oxidative stress in rodents, but there is controversy as to whether skeletal muscle mitochondrial biogenesis and function is altered...
  20. pmc IRS1-independent defects define major nodes of insulin resistance
    Kyle L Hoehn
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia
    Cell Metab 7:421-33. 2008
    ..These findings indicate that while insulin resistance is associated with multiple deficiencies, the most deleterious defects and the origin of insulin resistance occur independently of IRS...
  21. pmc The evolution of insulin resistance in muscle of the glucose infused rat
    Amanda E Brandon
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia
    Arch Biochem Biophys 509:133-41. 2011
    ..These results indicate that, in the presence of a nutrient overload, alterations in muscle insulin signaling occur, but after insulin resistance develops and appropriate changes in energy/nutrient sensing pathways occur...
  22. doi request reprint Fatty acid metabolism, energy expenditure and insulin resistance in muscle
    Nigel Turner
    Department of Pharmacology School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia Diabetes and Obesity Division, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia St Vincent s Clinical School, University of New South Wales, Sydney, New South Wales, Australia Department of Physiology, Monash University, Clayton, Victoria 3800, Australia
    J Endocrinol 220:T61-79. 2014
    ..It also outlines potential problems with models and measurements that may hinder as well as help improve our understanding of the links between FAs and insulin action. ..
  23. doi request reprint Adult-onset PYY overexpression in mice reduces food intake and increases lipogenic capacity
    Yan chuan Shi
    Neuroscience Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, NSW 2010, Australia
    Neuropeptides 46:173-82. 2012
    ..Taken together, these findings demonstrate that under physiological conditions, PYY reduces food intake while enhancing lipogenic capacity and insulin action, likely contributing to fuel assimilation in the postprandial state...
  24. ncbi request reprint Genetic ablation of the c-Cbl ubiquitin ligase domain results in increased energy expenditure and improved insulin action
    Juan C Molero
    Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW 2010, Australia
    Diabetes 55:3411-7. 2006
    ..These results indicate that c-Cbl ubiquitin ligase activity, but not c-Cbl-dependent activation of PI 3-kinase, plays a key role in the regulation of whole-body energy metabolism...
  25. ncbi request reprint Casitas b-lineage lymphoma-deficient mice are protected against high-fat diet-induced obesity and insulin resistance
    Juan C Molero
    Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW 2010, Australia
    Diabetes 55:708-15. 2006
    ..These studies are consistent with a role for c-Cbl in regulating nutrient partitioning in skeletal muscle and emphasize the potential of c-Cbl as a therapeutic target in the treatment of obesity and type 2 diabetes...
  26. doi request reprint Altered feeding differentially regulates circadian rhythms and energy metabolism in liver and muscle of rats
    Jane Reznick
    Garvan Institute of Medical Research, Darlinghurst, Sydney, Australia
    Biochim Biophys Acta 1832:228-38. 2013
    ..These data demonstrate that a mismatch of feeding and light/dark cycle disrupts tissue metabolism in muscle with significant consequences for whole body energy homeostasis...
  27. ncbi request reprint Docosahexaenoic acid (DHA) content of membranes determines molecular activity of the sodium pump: implications for disease states and metabolism
    Nigel Turner
    Metabolic Research Centre, University of Wollongong, 2522, Wollongong, NSW, Australia
    Naturwissenschaften 90:521-3. 2003
    ....
  28. ncbi request reprint Greater effect of diet than exercise training on the fatty acid profile of rat skeletal muscle
    Nigel Turner
    Metabolic Research Centre, Department of Biomedical Sciences, University of Wollongong, New South Wales, Australia
    J Appl Physiol 96:974-80. 2004
    ....
  29. pmc Muscle insulin resistance: a case of fat overconsumption, not mitochondrial dysfunction
    Edward W Kraegen
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Sydney NSW 2010, Australia
    Proc Natl Acad Sci U S A 105:7627-8. 2008
  30. ncbi request reprint Calorie restriction in mice: effects on body composition, daily activity, metabolic rate, mitochondrial reactive oxygen species production, and membrane fatty acid composition
    Sally C Faulks
    School of Biological Sciences, University of Wollongong, Wollongong, NSW 2522, Australia
    J Gerontol A Biol Sci Med Sci 61:781-94. 2006
    ..Changes in the fatty acid composition of phospholipids from liver, kidneys, heart, brain, and skeletal muscle were observed following 1 month of CR...
  31. ncbi request reprint How might you compare mitochondria from different tissues and different species?
    A J Hulbert
    Metabolic Research Centre and School of Biological Sciences, University of Wollongong, Wollongong, NSW, 2522, Australia
    J Comp Physiol B 176:93-105. 2006
    ..The molecular activity of mitochondrial cytochromes was found to be significantly positively correlated with the relative polyunsaturation of mitochondrial membrane lipids...
  32. pmc The effect of exercise on the skeletal muscle phospholipidome of rats fed a high-fat diet
    Todd W Mitchell
    School of Health Sciences, University of Wollongong, NSW 2522, Australia E mail
    Int J Mol Sci 11:3954-64. 2010
    ..These data suggest a possible reduction in phospholipid remodeling in the trained animals. This results in a decrease in the phospholipid n-3 to n-6 ratio that may in turn influence endurance capacity...
  33. pmc Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity
    Kyle L Hoehn
    Garvan Institute of Medical Research, Darlinghurst, NSW, Australia
    Cell Metab 11:70-6. 2010
    ..We conclude that negative energy balance is a prerequisite for weight reduction, and increased fatty acid oxidation per se has little, if any, effect to reduce adiposity...
  34. ncbi request reprint Sodium pump molecular activity and membrane lipid composition in two disparate ectotherms, and comparison with endotherms
    Nigel Turner
    Department of Biomedical Science, Metabolic Research Centre, University of Wollongong, Wollongong, NSW, 2522, Australia
    J Comp Physiol B 175:77-85. 2005
    ..003) correlation was observed between sodium pump molecular activity and the content of 22:6 (n-3) in the surrounding membrane. These results are discussed in relation to recent work which shows a similar relationship in endotherms...
  35. ncbi request reprint AMP-activated protein kinase and muscle insulin resistance
    Edward W Kraegen
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Sydney, NSW, Australia
    Front Biosci (Landmark Ed) 14:4658-72. 2009
    ..These issues are important in considering the AMPK pathway as a therapeutic target in insulin resistant states...
  36. pmc New insight into the mechanism by which acute physical exercise ameliorates insulin resistance
    Andrew J Hoy
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW 2010, Australia
    J Physiol 586:2251-2. 2008
  37. doi request reprint An Actn3 knockout mouse provides mechanistic insights into the association between alpha-actinin-3 deficiency and human athletic performance
    Daniel G MacArthur
    Institute for Neuromuscular Research, The Children s Hospital at Westmead, Sydney 2145, NSW, Australia
    Hum Mol Genet 17:1076-86. 2008
    ..These findings provide the first mechanistic explanation for the reported associations between R577X and human athletic performance and muscle function...
  38. doi request reprint The ω-3 and ω-6 fats in meals: a proposal for a simple new label
    Nigel Turner
    Metabolic Research Centre, University of Wollongong, Wollongong, New South Wales, Australia
    Nutrition 27:719-26. 2011
    ..Our goal in this study was to analyze the PUFA content of whole meals and produce a simple measurement to estimate the intake of these fatty acids...
  39. ncbi request reprint Molecular activity of sodium pumps in the kidney of mammals and birds
    Nigel Turner
    Metabolic Research Centre, University of Wollongong, New South Wales, Australia 2522
    Ann N Y Acad Sci 986:606-7. 2003
  40. doi request reprint Y2 and Y4 receptor signaling synergistically act on energy expenditure and physical activity
    Lei Zhang
    Neuroscience Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, Darlinghurst NSW 2010, Sydney, Australia
    Am J Physiol Regul Integr Comp Physiol 299:R1618-28. 2010
    ....
  41. pmc Contrasting metabolic effects of medium- versus long-chain fatty acids in skeletal muscle
    Magdalene K Montgomery
    Department of Pharmacology, School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia
    J Lipid Res 54:3322-33. 2013
    ..These effects potentially contribute to the beneficial metabolic actions of dietary MCFAs. ..
  42. pmc Loss of Krüppel-like factor 3 (KLF3/BKLF) leads to upregulation of the insulin-sensitizing factor adipolin (FAM132A/CTRP12/C1qdc2)
    Kim S Bell-Anderson
    School of Molecular Bioscience, University of Sydney, Sydney, New South Wales, Australia
    Diabetes 62:2728-37. 2013
    ..Boosting levels of adipolin via targeting of KLF3 offers a novel potential therapeutic strategy for the treatment of insulin resistance. ..
  43. pmc High passage MIN6 cells have impaired insulin secretion with impaired glucose and lipid oxidation
    Kim Cheng
    Diabetes and Transcription Factors Group, Garvan Institute of Medical Research, Sydney, NSW, Australia
    PLoS ONE 7:e40868. 2012
    ..We believe a number of gene expression changes occurred to produce this defect, with emphasis on Sirt3 and Nampt, two genes that have been implicated in maintenance of glucose homeostasis...
  44. doi request reprint Effects of vitamin D in skeletal muscle: falls, strength, athletic performance and insulin sensitivity
    Christian M Girgis
    Diabetes and Transcription Factors Group, Garvan Institute of Medical Research GIMR, Sydney, NSW, Australia Faculty of Medicine, University of Sydney, Sydney, NSW, Australia
    Clin Endocrinol (Oxf) 80:169-81. 2014
    ..This review evaluates evidence for the various roles of vitamin D in skeletal muscle and discusses controversies that have made this a dynamic field of research. ..
  45. doi request reprint Grb10 regulates the development of fiber number in skeletal muscle
    Lowenna J Holt
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, NSW 2010, Australia
    FASEB J 26:3658-69. 2012
    ..In addition, Grb10-ablated muscle from adult mice shows coordinate gene changes that oppose those of muscle wasting pathologies, highlighting Grb10 as a potential therapeutic target for these conditions...
  46. ncbi request reprint Fatty acid relationships in former cannabis users with schizophrenia
    Sharon Monterrubio
    Department of Psychology and Illawarra Institute for Mental Health, University of Wollongong, Northfields Avenue, NSW, 2522, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 30:280-5. 2006
    ..Future research may determine whether these FAs are involved in hypothesised links between anandamide abnormalities, cannabis use and stress in schizophrenia...
  47. doi request reprint Antidiabetic activities of triterpenoids isolated from bitter melon associated with activation of the AMPK pathway
    Min Jia Tan
    State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, China
    Chem Biol 15:263-73. 2008
    ..These findings indicate that cucurbitane triterpenoids, the characteristic constituents of M. charantia, may provide leads as a class of therapeutics for diabetes and obesity...
  48. ncbi request reprint Rosiglitazone enhances glucose tolerance by mechanisms other than reduction of fatty acid accumulation within skeletal muscle
    Sarah J Lessard
    Exercise Metabolism Group, RMIT University School of Medical Sciences, Bundoora, Victoria, Australia
    Endocrinology 145:5665-70. 2004
    ..Our data suggest, therefore, that rosiglitazone enhances glucose tolerance by mechanisms other than reduction of fatty acid accumulation within skeletal muscle...
  49. ncbi request reprint Why are some mitochondria more powerful than others: insights from comparisons of muscle mitochondria from three terrestrial vertebrates
    Helga Guderley
    Helga Guderley, Dép de Biologie, Universite Laval, Quebec, P Q Canada
    Comp Biochem Physiol B Biochem Mol Biol 142:172-80. 2005
    ..We suggest that the numbers of CCO and ANT together with the poly-unsaturation of phospholipids explain the higher oxidative capacities in muscle mitochondria from rats and cane toads...
  50. ncbi request reprint Modulation of Na,K-ATPase by phospholipids and cholesterol. II. Steady-state and presteady-state kinetics
    Flemming Cornelius
    Department of Biophysics, University of Aarhus, Ole Worms Alle 185, DK 8000, Denmark
    Biochemistry 42:8541-9. 2003
    ....
  51. pmc Proton conductance and fatty acyl composition of liver mitochondria correlates with body mass in birds
    Martin D Brand
    MRC Dunn Human Nutrition Unit, Hills Road, Cambridge CB2 2XY, UK
    Biochem J 376:741-8. 2003
    ..These correlations echo those seen in mammalian liver mitochondria, suggesting that they too are general for endotherms...
  52. doi request reprint The role of mitochondrial glycerol-3-phosphate acyltransferase-1 in regulating lipid and glucose homeostasis in high-fat diet fed mice
    Misak Yazdi
    AstraZeneca Research and Development, Pepparedsleden 1, S 431 83 Molndal, Sweden
    Biochem Biophys Res Commun 369:1065-70. 2008
    ..Thus, GPAT1-deficiency does not protect against HFD-induced obesity, hepatic steatosis or whole body glucose intolerance...
  53. ncbi request reprint Electric field strength of membrane lipids from vertebrate species: membrane lipid composition and Na+-K+-ATPase molecular activity
    Thomas Starke-Peterkovic
    School of Chemistry, University of Sydney, Sydney, NSW 2006, Australia
    Am J Physiol Regul Integr Comp Physiol 288:R663-70. 2005
    ..The fact that the dipole potential is maintained at a relatively constant value over a wide range of animal species suggests that it may play a fundamental role in ensuring correct ion pump conformation and function within the membrane...
  54. pmc Cholesterol effect on the dipole potential of lipid membranes
    Thomas Starke-Peterkovic
    School of Chemistry, University of Sydney, Sydney NSW 2006, Australia
    Biophys J 90:4060-70. 2006
    ..We suggest that this could be associated with a maximum in the strength of DMPC-cholesterol intermolecular forces at this composition...