Katherine Samaras

Summary

Affiliation: Garvan Institute of Medical Research
Country: Australia

Publications

  1. ncbi request reprint Iatrogenic Cushing's syndrome with osteoporosis and secondary adrenal failure in human immunodeficiency virus-infected patients receiving inhaled corticosteroids and ritonavir-boosted protease inhibitors: six cases
    Katherine Samaras
    Department of Endocrinology, St Vincent s Hospital and St Vincent s Clinic, Darlinghurst, New South Wales, 2010, Australia
    J Clin Endocrinol Metab 90:4394-8. 2005
  2. doi request reprint The impact of glucose disorders on cognition and brain volumes in the elderly: the Sydney Memory and Ageing Study
    Katherine Samaras
    Diabetes and Obesity Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia
    Age (Dordr) 36:977-93. 2014
  3. doi request reprint Immune cell-mediated inflammation and the early improvements in glucose metabolism after gastric banding surgery
    Katherine Samaras
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW, 2010, Australia
    Diabetologia 56:2564-72. 2013
  4. ncbi request reprint Bariatric surgery for type 2 diabetes: to whom and when?
    K Samaras
    Department of Endocrinology St Vincent s Hospital, Diabetes and Obesity Group, Garvan Institute of Medical Research, Sydney, Australia
    Minerva Endocrinol 38:47-58. 2013
  5. doi request reprint Reduced arterial stiffness after weight loss in obese type 2 diabetes and impaired glucose tolerance: the role of immune cell activation and insulin resistance
    Katherine Samaras
    Diabetes Program, Garvan Institute of Medical Research, Darlinghurst, Australia
    Diab Vasc Dis Res 10:40-8. 2013
  6. doi request reprint Take heart: bariatric surgery in obese patients with severe heart failure. Two case reports
    K Samaras
    Diabetes Program, Garvan Institute of Medical Research, Australia
    Heart Lung Circ 21:847-9. 2012
  7. doi request reprint The value of the metabolic syndrome concept in elderly adults: is it worth less than the sum of its parts?
    Katherine Samaras
    Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
    J Am Geriatr Soc 60:1734-41. 2012
  8. doi request reprint The burden of diabetes and hyperlipidemia in treated HIV infection and approaches for cardiometabolic care
    Katherine Samaras
    Department of Endocrinology, St Vincent s Hospital, Diabetes and Obesity Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia
    Curr HIV/AIDS Rep 9:206-17. 2012
  9. ncbi request reprint Metabolic consequences and therapeutic options in highly active antiretroviral therapy in human immunodeficiency virus-1 infection
    Katherine Samaras
    Diabetes Program, Garvan Institute of Medical Research, Department of Endocrinology, St Vincent s Hospital, 384 Victoria St, Darlinghurst, NSW 2010, Australia
    J Antimicrob Chemother 61:238-45. 2008
  10. doi request reprint Subcutaneous and visceral adipose tissue FTO gene expression and adiposity, insulin action, glucose metabolism, and inflammatory adipokines in type 2 diabetes mellitus and in health
    Katherine Samaras
    Department of Endocrinology, St Vincent s Hospital, 384 Victoria Street, Darlinghurst, NSW 2010, Australia
    Obes Surg 20:108-13. 2010

Detail Information

Publications46

  1. ncbi request reprint Iatrogenic Cushing's syndrome with osteoporosis and secondary adrenal failure in human immunodeficiency virus-infected patients receiving inhaled corticosteroids and ritonavir-boosted protease inhibitors: six cases
    Katherine Samaras
    Department of Endocrinology, St Vincent s Hospital and St Vincent s Clinic, Darlinghurst, New South Wales, 2010, Australia
    J Clin Endocrinol Metab 90:4394-8. 2005
    ....
  2. doi request reprint The impact of glucose disorders on cognition and brain volumes in the elderly: the Sydney Memory and Ageing Study
    Katherine Samaras
    Diabetes and Obesity Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia
    Age (Dordr) 36:977-93. 2014
    ..Preventing deterioration in glucose metabolism in the elderly may help preserve brain structure and function. ..
  3. doi request reprint Immune cell-mediated inflammation and the early improvements in glucose metabolism after gastric banding surgery
    Katherine Samaras
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW, 2010, Australia
    Diabetologia 56:2564-72. 2013
    ..We hypothesised that early changes in glucose metabolism following gastric banding surgery may relate to systemic inflammation, particularly cell-mediated immunity...
  4. ncbi request reprint Bariatric surgery for type 2 diabetes: to whom and when?
    K Samaras
    Department of Endocrinology St Vincent s Hospital, Diabetes and Obesity Group, Garvan Institute of Medical Research, Sydney, Australia
    Minerva Endocrinol 38:47-58. 2013
    ..The question of when bariatric surgery should be offered in the course of obesity-associated diabetes is discussed. Current guidelines and specialist society recommendations for bariatric surgery in diabetes are summarized...
  5. doi request reprint Reduced arterial stiffness after weight loss in obese type 2 diabetes and impaired glucose tolerance: the role of immune cell activation and insulin resistance
    Katherine Samaras
    Diabetes Program, Garvan Institute of Medical Research, Darlinghurst, Australia
    Diab Vasc Dis Res 10:40-8. 2013
    ..005). In morbidly obese dysglycaemic subjects, modest weight loss reduces arterial stiffness, the magnitude of which relates to improved markers of inflammation...
  6. doi request reprint Take heart: bariatric surgery in obese patients with severe heart failure. Two case reports
    K Samaras
    Diabetes Program, Garvan Institute of Medical Research, Australia
    Heart Lung Circ 21:847-9. 2012
    ..In selected patients with severe heart failure and concomitant morbid obesity, bariatric surgery may be a reasonable treatment option...
  7. doi request reprint The value of the metabolic syndrome concept in elderly adults: is it worth less than the sum of its parts?
    Katherine Samaras
    Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
    J Am Geriatr Soc 60:1734-41. 2012
    ..To determine whether the metabolic syndrome (MetS) or its components were more closely associated with disease states and inflammation in elderly adults...
  8. doi request reprint The burden of diabetes and hyperlipidemia in treated HIV infection and approaches for cardiometabolic care
    Katherine Samaras
    Department of Endocrinology, St Vincent s Hospital, Diabetes and Obesity Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia
    Curr HIV/AIDS Rep 9:206-17. 2012
    ..It also reviews the current evidence base and clinical guidelines for diabetes and lipid management and cardiometabolic prevention in HIV-infected HAART recipients...
  9. ncbi request reprint Metabolic consequences and therapeutic options in highly active antiretroviral therapy in human immunodeficiency virus-1 infection
    Katherine Samaras
    Diabetes Program, Garvan Institute of Medical Research, Department of Endocrinology, St Vincent s Hospital, 384 Victoria St, Darlinghurst, NSW 2010, Australia
    J Antimicrob Chemother 61:238-45. 2008
    ..The efficacy of therapeutic interventions for insulin resistance, hyperlipidaemia, body fat partitioning disorders and metabolic syndrome is summarized...
  10. doi request reprint Subcutaneous and visceral adipose tissue FTO gene expression and adiposity, insulin action, glucose metabolism, and inflammatory adipokines in type 2 diabetes mellitus and in health
    Katherine Samaras
    Department of Endocrinology, St Vincent s Hospital, 384 Victoria Street, Darlinghurst, NSW 2010, Australia
    Obes Surg 20:108-13. 2010
    ....
  11. doi request reprint Proinflammatory markers, insulin sensitivity, and cardiometabolic risk factors in treated HIV infection
    Katherine Samaras
    St Vincent s Hospital, Darlinghurst, New South Wales, Australia
    Obesity (Silver Spring) 17:53-9. 2009
    ..These factors may contribute to the accelerated diabetogenesis and cardiac risk observed in treated HIV infection...
  12. doi request reprint Prevalence and pathogenesis of diabetes mellitus in HIV-1 infection treated with combined antiretroviral therapy
    Katherine Samaras
    Diabetes and Obesity Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia
    J Acquir Immune Defic Syndr 50:499-505. 2009
    ..It also reviews the current understanding of mechanisms involved in the pathogenesis of type 2 diabetes in cART considering insulin resistance and insulin secretion, both requisites for the development of type 2 diabetes mellitus...
  13. ncbi request reprint Dietary intake in HIV-infected men with lipodystrophy: relationships with body composition, visceral fat, lipid, glucose and adipokine metabolism
    Katherine Samaras
    Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW 2010, Australia
    Curr HIV Res 7:454-61. 2009
    ..Only interventional, prospective studies will determine whether any nutritional strategy can assist in ameliorating the metabolic complications associated with HIV lipodystrophy...
  14. ncbi request reprint Prevalence of metabolic syndrome in HIV-infected patients receiving highly active antiretroviral therapy using International Diabetes Foundation and Adult Treatment Panel III criteria: associations with insulin resistance, disturbed body fat compartmental
    Katherine Samaras
    Diabetes and Obesity Programme, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia
    Diabetes Care 30:113-9. 2007
    ..The purpose of this study was to report the prevalence of metabolic syndrome in HIV-infected patients and compare insulin resistance and total body, limb, and visceral fat and adipokines in those with and without metabolic syndrome...
  15. ncbi request reprint Obesity is an important determinant of baseline serum C-reactive protein concentration in monozygotic twins, independent of genetic influences
    Jerry R Greenfield
    Department of Endocrinology, St Vincent s Hospital, Sydney, Australia
    Circulation 109:3022-8. 2004
    ..The aim of this study was to examine the relationship between CRP and accurately measured body fat, lipids, apolipoproteins, blood pressure, and environmental and behavioral factors, independent of genetic influences...
  16. ncbi request reprint Effect of pravastatin on body composition and markers of cardiovascular disease in HIV-infected men--a randomized, placebo-controlled study
    Patrick W G Mallon
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, 376 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia
    AIDS 20:1003-10. 2006
    ..To determine the effect of the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, pravastatin, on markers of cardiovascular risk and lipodystrophy in HIV-infected, protease inhibitor (PI)-treated men with hypercholesterolaemia...
  17. pmc The association between systemic inflammation and cognitive performance in the elderly: the Sydney Memory and Ageing Study
    Julian N Trollor
    Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales, 34 Botany Road, Sydney, NSW, Australia
    Age (Dordr) 34:1295-308. 2012
    ..Additional research is required to elucidate the pathophysiology and longitudinal development of these relationships...
  18. ncbi request reprint Moderate alcohol consumption, estrogen replacement therapy, and physical activity are associated with increased insulin sensitivity: is abdominal adiposity the mediator?
    Jerry R Greenfield
    Department of Endocrinology, St Vincent s Hospital, Sydney, Australia
    Diabetes Care 26:2734-40. 2003
    ..the contribution of abdominal adiposity to these relationships; and 3). whether gene-environment interactions mediate these associations...
  19. ncbi request reprint Moderate alcohol consumption, dietary fat composition, and abdominal obesity in women: evidence for gene-environment interaction
    Jerry R Greenfield
    Department of Endocrinology, St Vincent s Hospital, Darlinghurst, 2010 Sydney, Australia
    J Clin Endocrinol Metab 88:5381-6. 2003
    ..In conclusion, genetic risk modulates relationships between dietary factors and adiposity. Lower abdominal fat may mediate associations between dietary intake and type 2 diabetes risk...
  20. ncbi request reprint Altered myocellular and abdominal fat partitioning predict disturbance in insulin action in HIV protease inhibitor-related lipodystrophy
    Seng Khee Gan
    Metabolism and Diabetes Research Program, Garvan Institute of Medical Research, Sydney, Australia
    Diabetes 51:3163-9. 2002
    ..The results do not establish causation but emphasize the interrelationships among visceral fat, myocyte lipid, and insulin action...
  21. ncbi request reprint Beneficial postprandial effect of a small amount of alcohol on diabetes and cardiovascular risk factors: modification by insulin resistance
    Jerry R Greenfield
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Sydney, Australia
    J Clin Endocrinol Metab 90:661-72. 2005
    ..02) and HC meal (increase, 362 +/- 36 vs. 205 +/- 34 kcal/d; P = 0.0009), but suppressed fat and carbohydrate oxidation. Some of our findings may be mechanisms for lower diabetes and cardiovascular risks in moderate drinkers...
  22. pmc The association between pulse wave velocity and cognitive function: the Sydney Memory and Ageing Study
    Joel Singer
    Brain and Aging Research Program, School of Psychiatry, University of New South Wales, Sydney, Australia
    PLoS ONE 8:e61855. 2013
    ..This study examined the relationship between carotid-femoral PWV and specific domains of cognitive function in a non-demented elderly sample...
  23. ncbi request reprint No effect of rosiglitazone for treatment of HIV-1 lipoatrophy: randomised, double-blind, placebo-controlled trial
    Andrew Carr
    St Vincent s Hospital, Sydney, Australia
    Lancet 363:429-38. 2004
    ..We postulated that rosiglitazone would improve HIV lipoatrophy...
  24. doi request reprint Subcutaneous and visceral adipose tissue gene expression of serum adipokines that predict type 2 diabetes
    Katherine Samaras
    1 Department of Endocrinology, St Vincent s Hospital, Darlinghurst, New South Wales, Australia 2 Diabetes and Obesity Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
    Obesity (Silver Spring) 18:884-9. 2010
    ..Increased production of these proinflammatory molecules by VAT may explain the links observed between visceral obesity, insulin resistance, and diabetes risk...
  25. doi request reprint Systemic inflammation is associated with MCI and its subtypes: the Sydney Memory and Aging Study
    Julian N Trollor
    Department of Developmental Disability Neuropsychiatry, University of New South Wales, 34 Botany Road, Sydney, NSW 2052, Australia
    Dement Geriatr Cogn Disord 30:569-78. 2010
    ..This study examines the relationship between systemic inflammation and MCI subtypes...
  26. doi request reprint Low bone mineral density, renal dysfunction, and fracture risk in HIV infection: a cross-sectional study
    Alexandra Calmy
    HIV, Immunology and Infectious Diseases Unit, University of New South Wales, Sydney, Australia
    J Infect Dis 200:1746-54. 2009
    ..The role of proximal renal tubular dysfunction (PRTD) and alterations in bone metabolism in HIV-related low BMD are incompletely understood...
  27. ncbi request reprint Physical activity reduces genetic susceptibility to increased central systolic pressure augmentation: a study of female twins
    Jerry R Greenfield
    Department of Endocrinology, St Vincent s Hospital, Sydney, Australia
    J Am Coll Cardiol 42:264-70. 2003
    ..We sought to examine associations between the augmentation index (AI) and metabolic, adiposity, and lifestyle factors, independent of genetic influences, and to determine whether gene-environment interactions modulate these relationships...
  28. ncbi request reprint Regional intra-subject variability in abdominal adiposity limits usefulness of computed tomography
    Jerry R Greenfield
    Diabetes and Metabolism Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney NSW 2010, Australia
    Obes Res 10:260-5. 2002
    ....
  29. doi request reprint Macrophage inhibitory cytokine-1 is associated with cognitive impairment and predicts cognitive decline - the Sydney Memory and Aging Study
    Talia Fuchs
    Department of Developmental Disability Neuropsychiatry, School of Psychiatry, University of New South Wales, Sydney, NSW, 2010, Australia
    Aging Cell 12:882-9. 2013
    ..In summary, MIC-1/GDF15 levels are associated with cognitive performance and cognitive decline. Further research is required to determine the pathophysiology of this relationship. ..
  30. doi request reprint Efficacy of metformin for prevention of weight gain in psychiatric populations: a review
    Hannah Newall
    Faculty of Medicine, University of New South Wales, NSW, Australia
    Int Clin Psychopharmacol 27:69-75. 2012
    ..Further studies with adequate statistical power are required to determine the efficacy of metformin in those with chronic psychotic illness...
  31. ncbi request reprint Effect of postprandial insulinemia and insulin resistance on measurement of arterial stiffness (augmentation index)
    Jerry R Greenfield
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW 2010, Australia
    Int J Cardiol 114:50-6. 2007
    ..Whether physiological postprandial insulinemia similarly affects AIx measurements, and whether insulin resistance modifies this response, has not been studied...
  32. ncbi request reprint Insulin levels in insulin resistance: phantom of the metabolic opera?
    Katherine Samaras
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Sydney, New South Wales
    Med J Aust 185:159-61. 2006
    ..Individuals "at risk" of diabetes and atherosclerotic cardiac disease can be identified simply and inexpensively, using classic clinical techniques, such as history-taking, physical examination, and very basic investigations...
  33. doi request reprint The heart of the matter: cardiometabolic care in youth with psychosis
    Jackie Curtis
    Eastern Suburbs Mental Health Programme, Bondi Centre, Sydney, New South Wales, Australia
    Early Interv Psychiatry 6:347-53. 2012
    ....
  34. doi request reprint Postprandial lipid effects of low-dose ritonavir vs. raltegravir in HIV-uninfected adults
    Katherine Samaras
    Diabetes Program, Garvan Institute of Medical Research, and Department of Endocrinology, St Vincent s Hospital, Darlinghurst, Sydney, NSW, Australia
    AIDS 24:1727-31. 2010
    ..Half this risk appears attributable to fasting dyslipidemia, but half remains unexplained. We compared the fasting and postprandial effects of low-dose ritonavir and raltegravir on cardiovascular and metabolic risk factors...
  35. doi request reprint Metabolic abnormalities in an early psychosis service: a retrospective, naturalistic cross-sectional study
    Jackie Curtis
    Early Psychosis Programme, Bondi Centre, South Eastern Sydney Local Health Network, School of Psychiatry, University of New South Wales, Sydney, Australia
    Early Interv Psychiatry 5:108-14. 2011
    ..This study examined the prevalence of such abnormalities in a specialist early-intervention community mental health team...
  36. ncbi request reprint Insulin resistance, intra-abdominal fat, cardiovascular risk factors, and androgens in healthy young women with type 1 diabetes mellitus
    Jerry R Greenfield
    Diabetes and Metabolism Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia
    J Clin Endocrinol Metab 87:1036-40. 2002
    ..Our results demonstrate greater insulin resistance in a group of premenopausal women with type 1 diabetes compared with nondiabetic controls, unrelated to abdominal adiposity, lipids, or androgens...
  37. ncbi request reprint Evaluation of pituitary function in the fatigued patient: a review of 59 cases
    Jerry R Greenfield
    Department of Endocrinology, St Vincent s Hospital and St Vincent s Clinic and the Garvan Institute of Medical Research, Sydney, Australia
    Eur J Endocrinol 154:147-57. 2006
    ..The aim of this study was to review the results of dynamic pituitary testing in patients presenting with fatigue...
  38. ncbi request reprint In vivo, nucleoside reverse-transcriptase inhibitors alter expression of both mitochondrial and lipid metabolism genes in the absence of depletion of mitochondrial DNA
    Patrick W G Mallon
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, NSW 2010, Australia
    J Infect Dis 191:1686-96. 2005
    ..The effects of this mitochondrial dysfunction on lipid metabolism, at a molecular level in vivo, have not been described...
  39. doi request reprint Early changes in adipokine levels and baseline limb fat may predict HIV lipoatrophy over 2 years following initiation of antiretroviral therapy
    A Calmy
    St Vincent s Hospital, Sydney, Australia
    HIV Med 9:101-10. 2008
    ..We investigated whether metabolic and body composition parameters could predict the development of LD over 2 years in adults initiating antiretroviral therapy (ART)...
  40. doi request reprint Transplant recipients on the edge of the hypocalcemia abyss
    Paul Lee
    Department of Endocrinology, St Vincent s Hospital, New South Wales, Australia
    J Heart Lung Transplant 28:93-5. 2009
    ..Regular surveillance of calcium homeostasis should be incorporated into routine clinical care of transplant recipients...
  41. ncbi request reprint Coeliac disease in an Indian patient: an important diagnosis to consider
    Paul Lee
    Department of Endocrinology, St Vincent s Hospital, Sydney, NSW, Australia
    Med J Aust 189:336-7. 2008
  42. ncbi request reprint Type 1 diabetes is not associated with increased central abdominal obesity
    Jerry R Greenfield
    Diabetes Care 26:2703; author reply 2703-4. 2003
  43. ncbi request reprint Metabolic syndrome, cardiovascular disease and type 2 diabetes mellitus after initiation of antiretroviral therapy in HIV infection
    Handan Wand
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Australia
    AIDS 21:2445-53. 2007
    ..Metabolic syndrome (MS) identifies individuals at risk of cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). Little is known about MS and its consequences following initiation of antiretroviral therapy (ART)...
  44. pmc Contribution of metabolic and anthropometric abnormalities to cardiovascular disease risk factors
    Carl Grunfeld
    Circulation 118:e20-8. 2008
  45. ncbi request reprint Insulin resistance: more important to identify than quantify
    Katherine Samaras
    Nephrology (Carlton) 10:597-8. 2005
  46. ncbi request reprint Heritability of body fat using DXA
    Katherine Samaras
    Obes Res 13:2210; author reply 2211. 2005