T V Nguyen

Summary

Affiliation: Garvan Institute of Medical Research
Country: Australia

Publications

  1. pmc Important risk factors and attributable risk of vertebral fractures in the population-based Tromsø study
    Svanhild Waterloo
    Department of Community Medicine, University of Tromsø, Tromsø, Norway
    BMC Musculoskelet Disord 13:163. 2012
  2. doi request reprint Individualized fracture risk assessment: progresses and challenges
    Tuan V Nguyen
    Osteoporosis and Bone Biology Program, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
    Curr Opin Rheumatol 25:532-41. 2013
  3. doi request reprint Association between abdominal obesity and fracture risk: a prospective study
    Shuman Yang
    Division of Musculoskeletal Diseases, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia
    J Clin Endocrinol Metab 98:2478-83. 2013
  4. doi request reprint Genetics and the individualized prediction of fracture
    Tuan V Nguyen
    Osteoporosis and Bone Biology Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia
    Curr Osteoporos Rep 10:236-44. 2012
  5. pmc Prevalence of vertebral fractures in women and men in the population-based Tromsø Study
    Svanhild Waterloo
    Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, 9037 Tromsø, Norway
    BMC Musculoskelet Disord 13:3. 2012
  6. pmc Reference ranges for bone mineral density and prevalence of osteoporosis in Vietnamese men and women
    Lan T Ho-Pham
    Department of Internal Medicine, Pham Ngoc Thach University of Medicine, 86 2 Thanh Thai Street, Ho Chi Minh City, Vietnam
    BMC Musculoskelet Disord 12:182. 2011
  7. pmc Bone mineral density, body mass index and cigarette smoking among Iranian women: implications for prevention
    Azam Baheiraei
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, University of New South Wales, Sydney, Australia
    BMC Musculoskelet Disord 6:34. 2005
  8. pmc Contributions of lean mass and fat mass to bone mineral density: a study in postmenopausal women
    Lan T Ho-Pham
    Department of Internal Medicine, Pham Ngoc Thach University of Medicine, 86 2 Thanh Thai St, Ward 12, District 10, Ho Chi Minh City, Vietnam
    BMC Musculoskelet Disord 11:59. 2010
  9. pmc Effect of urbanization on bone mineral density: a Thai epidemiological study
    Chatlert Pongchaiyakul
    Division of Endocrinology, Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand
    BMC Musculoskelet Disord 6:5. 2005
  10. pmc Beta3-adrenergic receptor gene, body mass index, bone mineral density and fracture risk in elderly men and women: the Dubbo Osteoporosis Epidemiology Study (DOES)
    Claire Y Wang
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, University of New South Wales, Sydney, NSW, Australia
    BMC Med Genet 7:57. 2006

Collaborators

Detail Information

Publications82

  1. pmc Important risk factors and attributable risk of vertebral fractures in the population-based Tromsø study
    Svanhild Waterloo
    Department of Community Medicine, University of Tromsø, Tromsø, Norway
    BMC Musculoskelet Disord 13:163. 2012
    ..The aim of this study was to examine the contribution of important risk factors to the variability in vertebral fracture risk...
  2. doi request reprint Individualized fracture risk assessment: progresses and challenges
    Tuan V Nguyen
    Osteoporosis and Bone Biology Program, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
    Curr Opin Rheumatol 25:532-41. 2013
    ..The present review examines the validation of risk prediction models in osteoporosis and identifies some major challenges...
  3. doi request reprint Association between abdominal obesity and fracture risk: a prospective study
    Shuman Yang
    Division of Musculoskeletal Diseases, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia
    J Clin Endocrinol Metab 98:2478-83. 2013
    ..However, the relationship between abdominal fat mass (aFM) and fracture risk is unclear because of limited prospective data. The present study sought to examine the association between aFM, BMD, and fracture risk...
  4. doi request reprint Genetics and the individualized prediction of fracture
    Tuan V Nguyen
    Osteoporosis and Bone Biology Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia
    Curr Osteoporos Rep 10:236-44. 2012
    ..These results are consistent with the view that genetic profiling, when integrated in existing risk assessment models, can inform a more accurate prediction of fracture risk in an individual...
  5. pmc Prevalence of vertebral fractures in women and men in the population-based Tromsø Study
    Svanhild Waterloo
    Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, 9037 Tromsø, Norway
    BMC Musculoskelet Disord 13:3. 2012
    ..The aim of this population based study was to describe, for the first time, the age- and sex specific occurrence of osteoporotic vertebral fractures in Norway...
  6. pmc Reference ranges for bone mineral density and prevalence of osteoporosis in Vietnamese men and women
    Lan T Ho-Pham
    Department of Internal Medicine, Pham Ngoc Thach University of Medicine, 86 2 Thanh Thai Street, Ho Chi Minh City, Vietnam
    BMC Musculoskelet Disord 12:182. 2011
    ..The aim of this study was to examine the effect of different reference ranges in bone mineral density on the diagnosis of osteoporosis...
  7. pmc Bone mineral density, body mass index and cigarette smoking among Iranian women: implications for prevention
    Azam Baheiraei
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, University of New South Wales, Sydney, Australia
    BMC Musculoskelet Disord 6:34. 2005
    ..This study was designed to estimate the modifiable distribution and determinants of bone mineral density (BMD) among Iranian women in Australia...
  8. pmc Contributions of lean mass and fat mass to bone mineral density: a study in postmenopausal women
    Lan T Ho-Pham
    Department of Internal Medicine, Pham Ngoc Thach University of Medicine, 86 2 Thanh Thai St, Ward 12, District 10, Ho Chi Minh City, Vietnam
    BMC Musculoskelet Disord 11:59. 2010
    ..The present study was undertaken to test the hypothesis that lean mass is a better determinant of BMD than fat mass...
  9. pmc Effect of urbanization on bone mineral density: a Thai epidemiological study
    Chatlert Pongchaiyakul
    Division of Endocrinology, Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand
    BMC Musculoskelet Disord 6:5. 2005
    ..This cross-sectional study was designed to examine the difference in bone mineral density (BMD), a primary predictor of fracture risk, between urban and rural Thai populations...
  10. pmc Beta3-adrenergic receptor gene, body mass index, bone mineral density and fracture risk in elderly men and women: the Dubbo Osteoporosis Epidemiology Study (DOES)
    Claire Y Wang
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, University of New South Wales, Sydney, NSW, Australia
    BMC Med Genet 7:57. 2006
    ..The aim of study was to examine the inter-relationships between ADRB3 gene polymorphisms, BMI, BMD and fracture risk in elderly Caucasians...
  11. pmc Association between vitamin D insufficiency and tuberculosis in a Vietnamese population
    Lan T Ho-Pham
    Department of Internal Medicine, Pham Ngoc Thach University of Medicine, Thanh Thai Street, District 10, Ho Chi Minh City, Vietnam
    BMC Infect Dis 10:306. 2010
    ..This study sought to examine the association between vitamin D status, parathyroid hormone (PTH) and the risk of TB in a Vietnamese population...
  12. ncbi request reprint Limited utility of clinical indices for the prediction of symptomatic fracture risk in postmenopausal women
    Tuan V Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, 384 Victoria Street, 2010, Darlinghurst, NSW, Australia
    Osteoporos Int 15:49-55. 2004
    ..48. Clinical risk scores can be used to identify women likely to have low BMD (albeit with low specificity), but they are not a useful tool to identify women who will have a fracture...
  13. pmc Abdominal fat and hip fracture risk in the elderly: the Dubbo Osteoporosis Epidemiology Study
    Nguyen D Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, UNSW, Australia
    BMC Musculoskelet Disord 6:11. 2005
    ..It is not known whether abdominal fat is associated with hip fracture. The present study was designed to examine the association between abdominal fat and hip fracture in women and men aged 60+ years...
  14. ncbi request reprint Femoral neck bone loss predicts fracture risk independent of baseline BMD
    Tuan V Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, Australia
    J Bone Miner Res 20:1195-201. 2005
    ..In elderly women, greater loss of BMD at the femoral neck was associated with increased risk of fracture, independent of baseline BMD and age...
  15. ncbi request reprint Bone mineral density-independent association of quantitative ultrasound measurements and fracture risk in women
    Tuan V Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, Australia
    Osteoporos Int 15:942-7. 2004
    ..The combination of QUS and BMD measurements may improve the accuracy of identification of women who will sustain a fracture...
  16. ncbi request reprint Contribution of the collagen I alpha1 and vitamin D receptor genes to the risk of hip fracture in elderly women
    Tuan V Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, New South Wales 2010, Australia
    J Clin Endocrinol Metab 90:6575-9. 2005
    ..Hip fracture is partially genetically determined. The present study was designed to examine the contributions of vitamin D receptor (VDR) and collagen I alpha1 (COLIA1) genotypes to the liability to hip fracture in postmenopausal women...
  17. ncbi request reprint Reproducibility and concordance in quantitative ultrasound measurements between densitometers: a comparative study
    Tuan V Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, Sydney, Australia
    J Clin Densitom 6:337-44. 2003
    ..These data suggest that although there are systematic differences between the UBIS and Achilles+ scanners in QUS measurements, the precision of the two instruments is equivalent...
  18. pmc Bone turnover in elderly men: relationships to change in bone mineral density
    Tuan V Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, Sydney, Australia
    BMC Musculoskelet Disord 8:13. 2007
    ..an individual; (ii) is there a relationship between baseline measurements of bone turnover markers and subsequent change in BMD; and (iii) is there a relationship between changes in bone turnover markers and changes in femoral neck BMD?..
  19. ncbi request reprint Genetic determination of bone mineral density: evidence for a major gene
    Tuan V Nguyen
    Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia
    J Clin Endocrinol Metab 88:3614-20. 2003
    ..These findings clearly support the hypothesis that a large component of the variance in BMD is under genetic control, with strong evidence for a major gene locus influencing BMD transmission...
  20. ncbi request reprint Pharmacogenomics of osteoporosis: opportunities and challenges
    T V Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, Sydney, Australia
    J Musculoskelet Neuronal Interact 6:62-72. 2006
    ....
  21. ncbi request reprint Influence of demographic factors and sport type on growth hormone-responsive markers in elite athletes
    A E Nelson
    Garvan Institute of Medical Research and Department of Endocrinology, Darlinghurst, New South Wales 2010, Australia
    J Clin Endocrinol Metab 91:4424-32. 2006
    ..GH-responsive markers of the IGF system and of collagen turnover hold promise as the basis of a GH doping test...
  22. doi request reprint Quantitative ultrasound and fracture risk prediction in non-osteoporotic men and women as defined by WHO criteria
    M Y Chan
    Osteoporosis and Bone Biology Program, Garvan Institute of Medical Research, 384 Victoria Street, Sydney, NSW 2010, Australia
    Osteoporos Int 24:1015-22. 2013
    ..e., BMD T-score > -2.5). We found that calcaneal QUS is an independent predictor of fracture risk in women with non-osteoporotic bone mineral density (BMD)...
  23. doi request reprint Development of prognostic nomograms for individualizing 5-year and 10-year fracture risks
    N D Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, 384 Victoria Street, Darlinghurst, Sydney, NSW, 2010, Australia
    Osteoporos Int 19:1431-44. 2008
    ..We have developed clinical nomograms for predicting 5-year and 10-year fracture risks for any elderly man or woman. The nomograms used age and information concerning fracture history, fall history, and BMD T-score or body weight...
  24. ncbi request reprint Genetic and environmental correlations between bone formation and bone mineral density: a twin study
    M Harris
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, NSW, Australia
    Bone 22:141-5. 1998
    ..These findings indicate that BSAP and BMD are heritable and negatively correlated. However, the genetic loci influencing BSAP and BMD appear to be largely independent as are any environmental factors...
  25. ncbi request reprint Femoral neck axis length, height loss and risk of hip fracture in males and females
    J R Center
    Bone and Mineral Research Division, Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, Australia
    Osteoporos Int 8:75-81. 1998
    ..Moreover, FNAL appears to have limited utility in the prediction of hip fracture risk and any role of HAL in the prediction of hip fracture does not relate to its major component of femoral neck length...
  26. doi request reprint Prognosis of fracture: evaluation of predictive accuracy of the FRAX algorithm and Garvan nomogram
    S K Sandhu
    Osteoporosis and Bone Biology Program, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
    Osteoporos Int 21:863-71. 2010
    ..These data emphasize the importance of external validation before widespread clinical implementation of prognostic tools in different cohorts...
  27. ncbi request reprint Discordance of longitudinal changes in bone density between densitometers
    S A Frost
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, NSW, Australia
    Bone 41:690-7. 2007
    ..Even though a high concordance between the densitometers was observed on a single measurement occasion, a significant discordance in longitudinal changes in BMD was observed...
  28. ncbi request reprint Development of a nomogram for individualizing hip fracture risk in men and women
    N D Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia
    Osteoporos Int 18:1109-17. 2007
    ..We have developed a nomogram for predicting the absolute risk of hip fracture for any individual by using clinical factors, including age, prior fracture and fall, in addition to BMD that was based on a 15-year follow-up cohort study...
  29. ncbi request reprint Risk factors for proximal humerus, forearm, and wrist fractures in elderly men and women: the Dubbo Osteoporosis Epidemiology Study
    T V Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, Australia
    Am J Epidemiol 153:587-95. 2001
    ..0, 3.6) and a history of falls (women: RR = 1.9, 95% CI: 1.4, 2.6) were also significant. These data suggest that elderly men and women largely share common risk factors for upper limb fractures and that FNBMD is the primary risk factor...
  30. ncbi request reprint Genetic influences on central abdominal fat: a twin study
    D G Carey
    Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, NSW, Australia
    Int J Obes Relat Metab Disord 20:722-6. 1996
    ..While significant genetic influences on body mass index (BMI), total body and subcutaneous fat have been demonstrated, the inheritance of central abdominal obesity, has not been studied...
  31. ncbi request reprint Association between breast cancer and bone mineral density: the Dubbo Osteoporosis Epidemiology Study
    T V Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research St Vincent s Hospital, NSW 2010, Sydney, Australia
    Maturitas 36:27-34. 2000
    ..D.) years, as part of the Dubbo Osteoporosis Epidemiology Study (Australia)...
  32. ncbi request reprint Residual lifetime risk of fractures in women and men
    Nguyen D Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, New South Wales, Australia
    J Bone Miner Res 22:781-8. 2007
    ..Among those with BMD T-scores < or = -2.5, the risks increased to 65% in women and 42% in men...
  33. ncbi request reprint Clinical risk indices, prediction of osteoporosis, and prevention of fractures: diagnostic consequences and costs
    Chatlert Pongchaiyakul
    Bone and Mineral Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW, Australia
    Osteoporos Int 16:1444-50. 2005
    ..Its use in the general population can result in a high false-positive rate and incur significant cost to the community...
  34. ncbi request reprint Bone resorption and osteoporotic fractures in elderly men: the dubbo osteoporosis epidemiology study
    Christian Meier
    Bone Research Program, ANZAC Research Institute, University of Sydney, Sydney, Australia
    J Bone Miner Res 20:579-87. 2005
    ..3 years, high bone resorption as assessed by S-ICTP was associated with increased risk of osteoporotic fracture, independent of BMD. Combining measurements of BMD and bone turnover may improve fracture prediction in elderly men...
  35. doi request reprint Enhancement of absolute fracture risk prognosis with genetic marker: the collagen I alpha 1 gene
    Bich N H Tran
    Osteoporosis and Bone Biology Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, 2010 Sydney, NSW, Australia
    Calcif Tissue Int 85:379-88. 2009
    ..The nonograms presented here can be useful for individualizing the short- and intermediate-term prognosis of fracture risk and help identify high-risk individuals for intervention for appropriate management of osteoporosis...
  36. ncbi request reprint Mortality after all major types of osteoporotic fracture in men and women: an observational study
    J R Center
    Bone and Mineral Research Division, Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, New South Wales, Australia
    Lancet 353:878-82. 1999
    ..Mortality increases after hip fractures in women and more so in men. Little is known, however, about mortality after other fractures. We investigated the mortality associated with all fracture types in elderly women and men...
  37. ncbi request reprint Hormonal and biochemical parameters in the determination of osteoporosis in elderly men
    J R Center
    Bone and Mineral Research Program, Garvan Institute of Medical Research, Sydney, New South Wales
    J Clin Endocrinol Metab 84:3626-35. 1999
    ....
  38. ncbi request reprint Identification of high-risk individuals for hip fracture: a 14-year prospective study
    Nguyen D Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, University of New South Wales, Sydney, New South Wales, Australia
    J Bone Miner Res 20:1921-8. 2005
    ..The combination of these risk factors accounted for 57% and 37% of hip fractures in women and men, respectively...
  39. ncbi request reprint Erythropoietin administration does not influence the GH--IGF axis or makers of bone turnover in recreational athletes
    A E Nelson
    Garvan Institute of Medical Research and Department of Endocrinology, Darlinghurst, NSW, Australia
    Clin Endocrinol (Oxf) 63:305-9. 2005
    ..The aim was to determine whether r-HuEPO induces similar effects on the IGF-system and collagen turnover in healthy athletes...
  40. ncbi request reprint Quality of life in osteoporosis: reliability, consistency, and validity of the Osteoporosis Assessment Questionnaire
    A G Randell
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, NSW, Australia
    J Rheumatol 25:1171-9. 1998
    ..To determine the reliability, consistency, and clinical utility of the Osteoporosis Assessment Questionnaire (OPAQ), an AIMS2 based self-assessment questionnaire...
  41. ncbi request reprint Effects of physical activity and dietary calcium intake on bone mineral density and osteoporosis risk in a rural Thai population
    C Pongchaiyakul
    Division of Endocrinology, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Osteoporos Int 15:807-13. 2004
    ..These results suggest that in the Thai population, low dietary calcium intake and low physical activity together with advancing years since menopause were independent risk factors for low BMD...
  42. ncbi request reprint Risk of subsequent fracture after low-trauma fracture in men and women
    Jacqueline R Center
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, University of New South Wales, Sydney, Australia
    JAMA 297:387-94. 2007
    ..There are few published long-term data on absolute risk of subsequent fracture (refracture) following initial low-trauma fracture in women and fewer in men...
  43. ncbi request reprint Age-related changes in serum testosterone and sex hormone binding globulin in Australian men: longitudinal analyses of two geographically separate regional cohorts
    Peter Y Liu
    Department of Andrology, Concord Hospital and ANZAC Research Institute, University of Sydney, Sydney, New South Wales 2139, Australia
    J Clin Endocrinol Metab 92:3599-603. 2007
    ..Cross-sectional studies from different populations show a variable decline in blood testosterone concentrations as men age. Few population representative cohorts have been followed up over time...
  44. ncbi request reprint Genetic effects on bone loss in peri- and postmenopausal women: a longitudinal twin study
    Joanna Makovey
    Institute of Bone and Joint Research, Royal North Shore Hospital, University of Sydney, Sydney, Australia
    J Bone Miner Res 22:1773-80. 2007
    ..Results of genetic model-fitting analysis indicated genetic effects on bone loss account for approximately 40% of the between-individual variation in bone loss at the lumbar spine, forearm, and whole body...
  45. ncbi request reprint Incidence of hip and other osteoporotic fractures in elderly men and women: Dubbo Osteoporosis Epidemiology Study
    Kevin P Chang
    Bone and Mineral Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW, Australia
    J Bone Miner Res 19:532-6. 2004
    ..Approximately one-half of hip fractures occurred before 80 years in men and two-thirds before 85 years in women. The age distribution of hip fractures underlines the need for earlier intervention in osteoporosis...
  46. doi request reprint Incidence and risk factors for low trauma fractures in men with prostate cancer
    Henrik G Ahlborg
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia
    Bone 43:556-60. 2008
    ..The present study sought to determine the incidence of low trauma fracture in men with prostate cancer (PC), and to characterize the association between potential risk factors and fracture risk in these men...
  47. doi request reprint Pharmacogenetics of osteoporosis and the prospect of individualized prognosis and individualized therapy
    Tuan V Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
    Curr Opin Endocrinol Diabetes Obes 15:481-8. 2008
    ..Description of recent progress in genetics and pharmacogenetics of osteoporosis...
  48. ncbi request reprint Volumetric bone density at the femoral neck as a common measure of hip fracture risk for men and women
    Jacqueline R Center
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital and University of New South Wales, Sydney, New South Wales 2010, Australia
    J Clin Endocrinol Metab 89:2776-82. 2004
    ..It needs further exploration for a role in assessment of hip fracture risk across the sexes and particularly in men...
  49. doi request reprint Expression of S100A2 calcium-binding protein predicts response to pancreatectomy for pancreatic cancer
    Andrew V Biankin
    Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW, Australia
    Gastroenterology 137:558-68, 568.e1-11. 2009
    ..We evaluated the utility of multiple biomarkers from distinct biologic pathways as potential predictive markers of response to pancreatectomy and patient survival...
  50. doi request reprint Osteoporosis medication and reduced mortality risk in elderly women and men
    Jacqueline R Center
    Garvan Institute of Medical Research, and St Vincent s Hospital, Sydney, New South Wales, Australia
    J Clin Endocrinol Metab 96:1006-14. 2011
    ..Osteoporotic fractures are associated with premature mortality. Antiresorptive treatment reduces refracture but mortality reduction is unclear...
  51. ncbi request reprint Psychometric properties of the Persian version of the osteoporosis knowledge and health belief questionnaires
    Azam Baheiraei
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, University of New South Wales, Sydney, NSW, Australia
    Maturitas 50:134-9. 2005
  52. pmc Association between LRP5 polymorphism and bone mineral density: a Bayesian meta-analysis
    Bich N H Tran
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, Australia
    BMC Med Genet 9:55. 2008
    ..Subsequent population-based studies of the association between the LRP5 gene and BMD have yielded conflicting results. The present study was aimed at examining the association between LRP5 gene and BMD by using meta-analysis...
  53. doi request reprint Association between hypertension and fragility fracture: a longitudinal study
    S Yang
    Division of Musculoskeletal Diseases, Garvan Institute of Medical Research, 384 Victoria Street, Sydney, New South Wales, 2010, Australia
    Osteoporos Int 25:97-103. 2014
    ..Hypertension is an independent risk factor for osteoporosis and osteoporotic fracture in postmenopausal women...
  54. ncbi request reprint p14ARF protein expression is a predictor of both relapse and survival in squamous cell carcinoma of the anterior tongue
    Rhonda A Kwong
    Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
    Clin Cancer Res 11:4107-16. 2005
    ..This study addressed the role of p14(ARF) as a potential prognostic marker in this disease...
  55. ncbi request reprint Contribution of hip strength indices to hip fracture risk in elderly men and women
    Henrik G Ahlborg
    Bone and Mineral Research Program, Garvan Institute of Medical Research, Sydney, Australia, and Department of Orthopaedics, Malmo University Hospital, Sweden
    J Bone Miner Res 20:1820-7. 2005
    ..However, the contribution of each of these indices to hip fracture prediction was modest in the presence of BMD...
  56. doi request reprint Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women
    Dana Bliuc
    Garvan Institute of Medical Research, 384 Victoria St, Sydney, NSW 2010, Australia
    JAMA 301:513-21. 2009
    ..There are few data on long-term mortality following osteoporotic fracture and fewer following subsequent fracture...
  57. ncbi request reprint Bone loss, weight loss, and weight fluctuation predict mortality risk in elderly men and women
    Nguyen D Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, New South Wales, Australia
    J Bone Miner Res 22:1147-54. 2007
    ..Low baseline BMD, rate of BMD loss, weight loss, and weight fluctuation are significant predictors of all-cause mortality in elderly men and women, independent of each other and of age, incident fracture, and concomitant diseases...
  58. ncbi request reprint Anti-hip fracture efficacy of biophosphonates: a Bayesian analysis of clinical trials
    Nguyen D Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, University of New South Wales, Sydney, Australia
    J Bone Miner Res 21:340-9. 2006
    ..This Bayesian meta-analysis quantitatively reviewed data from 12 randomized clinical trials with 18,667 patients and found that bisphosphonate treatment was associated with a reduced risk for hip fracture by 42%...
  59. ncbi request reprint Overexpression of E2F-1 is associated with increased disease-free survival in squamous cell carcinoma of the anterior tongue
    Rhonda A Kwong
    Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia
    Clin Cancer Res 9:3705-11. 2003
    ..This study sought to determine the relationship between E2F-1 and retinoblastoma protein (pRb) expression and disease outcome in squamous cell carcinoma (SCC) of the anterior tongue...
  60. ncbi request reprint Risk factors for fracture in nonosteoporotic men and women
    Nguyen D Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, 384 Victoria Street, Darlinghurst, Sydney, New South Wales 2010, Australia
    J Clin Endocrinol Metab 92:955-62. 2007
    ..It is not known which factors are associated with fracture in nonosteoporotic elderly. The aim of this study was to assess the association between fall-related risk factors and fracture risk in men and women without osteoporosis...
  61. ncbi request reprint Osteoporosis: underrated, underdiagnosed and undertreated
    Tuan V Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia
    Med J Aust 180:S18-22. 2004
    ..Simple measures like vitamin D and calcium supplementation and use of hip protectors can reduce hip fractures, particularly in institutionalised and housebound elderly people..
  62. ncbi request reprint On the association between statin and fracture: a Bayesian consideration
    Nguyen D Nguyen
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia
    Bone 40:813-20. 2007
    ..This study utilized the Bayesian approach to combine existing evidence and update the association with consideration of potential bias...
  63. ncbi request reprint Exploring factors influencing osteoporosis prevention and control: a qualitative study of Iranian men and women in Australia
    Azam Baheiraei
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, University of New South Wales, Sydney, NSW, Australia
    Maturitas 54:127-34. 2006
    ..To explore the understanding of osteoporosis risk factors and barriers that influence osteoporosis prevention and control in order to better inform the development of culturally appropriate osteoporosis preventive strategies...
  64. doi request reprint Timing of repeat BMD measurements: development of an absolute risk-based prognostic model
    Steven A Frost
    Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent s Hospital, Sydney, New South Wales, Australia
    J Bone Miner Res 24:1800-7. 2009
    ..The prognostic model and approach presented in this study may help improve the individualization and management of osteoporosis...
  65. ncbi request reprint Asymptomatic vertebral deformity as a major risk factor for subsequent fractures and mortality: a long-term prospective study
    Chatlert Pongchaiyakul
    Bone and Mineral Research Program, Garvan Institute of Medical Research, Sydney, Australia
    J Bone Miner Res 20:1349-55. 2005
    ..In elderly men and women, asymptomatic vertebral deformity was found to be associated with subsequent risk of symptomatic fractures, particularly vertebral fracture, and increased risk of mortality after a fracture...
  66. doi request reprint Within-subject variability and analytic imprecision of insulinlike growth factor axis and collagen markers: implications for clinical diagnosis and doping tests
    Tuan V Nguyen
    Garvan Institute of Medical Research and Department of Endocrinology, Sydney, Australia
    Clin Chem 54:1268-76. 2008
    ..We sought to determine short-term within-subject variability of these markers in a large cohort of healthy individuals...
  67. doi request reprint Multiple genetic loci for bone mineral density and fractures
    Unnur Styrkarsdottir
    deCODE Genetics, Reykjavik, Iceland
    N Engl J Med 358:2355-65. 2008
    ..Bone mineral density influences the risk of osteoporosis later in life and is useful in the evaluation of the risk of fracture. We aimed to identify sequence variants associated with bone mineral density and fracture...
  68. ncbi request reprint Association between clinically abnormal observations and subsequent in-hospital mortality: a prospective study
    Michael Buist
    Department of Intensive Care, Dandenong Hospital, P O Box 478, Dandenong, VIC 3175, Australia
    Resuscitation 62:137-41. 2004
    ..The aim of this study was to determine the predictive value of selected abnormal clinical observations in a ward population for subsequent in-hospital mortality...
  69. ncbi request reprint Does hip strength measures account for the difference in hip fracture incidence between the Chinese and Caucasian populations?
    Nguyen D Nguyen
    Bone 35:998-9; author reply 1000. 2004
  70. ncbi request reprint Development and validation of a new clinical risk index for prediction of osteoporosis in Thai women
    Chatlert Pongchaiyakul
    Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand
    J Med Assoc Thai 87:910-6. 2004
    ....
  71. ncbi request reprint Pharmacogenetics of anti-resorptive therapy efficacy: a Bayesian interpretation
    Tuan V Nguyen
    Osteoporos Int 16:857-60. 2005
  72. ncbi request reprint Contribution of lean tissue mass to the urban-rural difference in bone mineral density
    Chatlert Pongchaiyakul
    Department of Endocrinology, Khon Kaen University Medical School, Khon Kaen, Thailand
    Osteoporos Int 16:1761-8. 2005
    ..These data are thus consistent with the hypothesis that the urban-rural difference in BMD at a weight-bearing site is in part associated with the urban-rural difference in lean mass...
  73. ncbi request reprint Estimated volumetric bone mineral density in a rural Thai men and women: Khon Kaen Osteoporosis Study (KKOS)
    Chatlert Pongchaiyakul
    Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    J Med Assoc Thai 88:S46-52. 2005
    ..Estimated vFNBMD shows only small sex-correlated differences in bone density. Estimated vFNBMD was more sensitive than aFNBMD, when used to define the osteoporotic cut-offs in men, while it was less sensitive than aFNBMD in women...
  74. ncbi request reprint Prediction of percentage body fat in rural thai population using simple anthropometric measurements
    Chatlert Pongchaiyakul
    Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002 Thailand
    Obes Res 13:729-38. 2005
    ..To develop and validate sex-specific equations for predicting percentage body fat (%BF) in rural Thai population, based on BMI and anthropometric measurements...
  75. ncbi request reprint Defining obesity by body mass index in the Thai population: an epidemiologic study
    Chatlert Pongchaiyakul
    Division of Endocrinology and Metabolism, Dept Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand 40002
    Asia Pac J Clin Nutr 15:293-9. 2006
    ..In conclusion, for the Thai population, BMI is a reasonably useful indicator of obesity; however, the cut-off values of BMI for diagnosing obesity should be lowered to 27 kg/m2 in men and 25 kg/m2 in women...
  76. ncbi request reprint Assessment of low bone mass in Vietnamese: comparison of QUS calcaneal ultrasonometer and data-derived T-scores
    Vu T T Thuy
    Department of Rheumatology, Bach Mai Hospital, Hanoi, Vietnam
    J Bone Miner Metab 21:114-9. 2003
    ..The instrument-derived T-score is not appropriate for the diagnosis of osteoporosis in the Vietnamese population...
  77. ncbi request reprint Prevalence of osteoporosis in Thai men
    Chatlert Pongchaiyakul
    Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    J Med Assoc Thai 89:160-9. 2006
    ..Osteoporosis is a growing health problem not only in women but also in men. However, there is a scarcity of epidemiologic data to study osteoporosis in Thai men...
  78. ncbi request reprint Genetics of bone mineral density: evidence for a major pleiotropic effect from an intercontinental study
    Gregory Livshits
    Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Bone Miner Res 19:914-23. 2004
    ..In addition to possible shared (pleiotropic) genetic and environmental effects, each of the BMD variables may also be determined by site-specific genetic factors...
  79. ncbi request reprint Prevalence of metabolic syndrome and its relationship to weight in the Thai population
    Chatlert Pongchaiyakul
    Division of Endocrinology and Metabolism, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    J Med Assoc Thai 90:459-67. 2007
    ..The objectives of the present study were to estimate the prevalence of MetS and to find an optimal BMI cut-off value for defining obesity in the Thai population...
  80. ncbi request reprint Risk assessment and fracture discrimination by ultrasound: the debate continues
    Tuan V Nguyen
    J Bone Miner Res 20:536-8; author reply 539-40. 2005
  81. doi request reprint Endogenous sex hormones and incident fracture risk in older men: the Dubbo Osteoporosis Epidemiology Study
    Christian Meier
    Division of Endocrinology, Diabetes and Clinical Nutrition, University Hospital Basel, Switzerland
    Arch Intern Med 168:47-54. 2008
    ..We prospectively examined the relationship between serum levels of testosterone and estradiol and future fracture risk in community-dwelling men...
  82. ncbi request reprint Serum cathepsin K concentrations reflect osteoclastic activity in women with postmenopausal osteoporosis and patients with Paget's disease
    Christian Meier
    Bone Research Program, ANZAC Research Institute, University of Sydney, Australia
    Clin Lab 52:1-10. 2006
    ..We assessed the usefulness of serum cathepsin K as a marker of bone turnover in cross-sectional and longitudinal studies of patients with metabolic bone disease...