Cindy S Ma
Affiliation: Garvan Institute of Medical Research
Ma C, Wong N, Rao G, Avery D, Torpy J, Hambridge T, et al
. Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies. J Allergy Clin Immunol. 2015;136:993-1006.e1 pubmed publisher
..These findings shed new light on TFH cell biology and the integrated signaling pathways required for their generation, maintenance, and effector function and explain the compromised humoral immunity seen in patients with some PIDs. ..
Ma C. Human T Follicular Helper Cells in Primary Immunodeficiency: Quality Just as Important as Quantity. J Clin Immunol. 2016;36 Suppl 1:40-7 pubmed publisher
..In particular it is increasingly evident that the quality of the Tfh cells that are generated, is just as important as the quantity. ..
Tangye S, Pillay B, Randall K, Avery D, Phan T, Gray P, et al
. Dedicator of cytokinesis 8-deficient CD4+ T cells are biased to a TH2 effector fate at the expense of TH1 and TH17 cells. J Allergy Clin Immunol. 2017;139:933-949 pubmed publisher