Ruta Gupta

Summary

Affiliation: Garvan Institute of Medical Research
Country: Australia

Publications

  1. ncbi Review: Mouse models of inflammatory bowel disease--insights into the mechanisms of inflammation-associated colorectal cancer
    Dessislava Mladenova
    Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney NSW 2010, Australia
    In Vivo 26:627-46. 2012
  2. ncbi Mutated in colorectal cancer protein modulates the NFκB pathway
    Nicholas D Sigglekow
    Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Sydney NSW 2010, Australia
    Anticancer Res 32:73-9. 2012
  3. ncbi Deciphering the colon cancer genes--report of the InSiGHT-Human Variome Project Workshop, UNESCO, Paris 2010
    Maija R J Kohonen-Corish
    Cancer Research Program, Garvan Institute of Medical Research, Sydney, NSW, Australia
    Hum Mutat 32:491-4. 2011
  4. ncbi The NSAID sulindac is chemopreventive in the mouse distal colon but carcinogenic in the proximal colon
    Dessislava Mladenova
    Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst Sydney NSW 2010, Australia
    Gut 60:350-60. 2011
  5. ncbi How to catch all those mutations--the report of the third Human Variome Project Meeting, UNESCO Paris, May 2010
    Maija R J Kohonen-Corish
    Cancer Research Program, Garvan Institute of Medical Research, St Vincent s Clinical School, University of NSW, Sydney, NSW, Australia
    Hum Mutat 31:1374-81. 2010
  6. ncbi Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer
    M R J Kohonen-Corish
    Cancer Research Program, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
    Oncogene 26:4435-41. 2007
  7. ncbi Promoter hypermethylation of the O(6)-methylguanine DNA methyltransferase gene and microsatellite instability in metastatic melanoma
    Maija R J Kohonen-Corish
    Cancer Research Program, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
    J Invest Dermatol 126:167-71. 2006
  8. ncbi Gene symbol: MSH2. Disease: Hereditary nonpolyposis colorectal cancer
    R Otway
    John Curtin School of Medical Research, Australian National University, Canberra
    Hum Genet 116:539. 2005
  9. ncbi Gene symbol: MSH2. Disease: Hereditary nonpolyposis colorectal cancer
    R Otway
    John Curtin School of Medical Research, Australian National University, Canberra
    Hum Genet 116:538. 2005
  10. ncbi Gene symbol: MSH2. Disease: Hereditary nonpolyposis colorectal cancer
    R Otway
    John Curtin School of Medical Research, Australian National University, Canberra
    Hum Genet 116:538. 2005

Collaborators

Detail Information

Publications16

  1. ncbi Review: Mouse models of inflammatory bowel disease--insights into the mechanisms of inflammation-associated colorectal cancer
    Dessislava Mladenova
    Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney NSW 2010, Australia
    In Vivo 26:627-46. 2012
    ..This review focuses on inflammation-associated colorectal cancer in mouse models of the disease and highlights emerging research trends...
  2. ncbi Mutated in colorectal cancer protein modulates the NFκB pathway
    Nicholas D Sigglekow
    Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Sydney NSW 2010, Australia
    Anticancer Res 32:73-9. 2012
    ..Therefore, we aimed to determine whether MCC modulates NFκB activation in colorectal cancer...
  3. ncbi Deciphering the colon cancer genes--report of the InSiGHT-Human Variome Project Workshop, UNESCO, Paris 2010
    Maija R J Kohonen-Corish
    Cancer Research Program, Garvan Institute of Medical Research, Sydney, NSW, Australia
    Hum Mutat 32:491-4. 2011
    ....
  4. ncbi The NSAID sulindac is chemopreventive in the mouse distal colon but carcinogenic in the proximal colon
    Dessislava Mladenova
    Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst Sydney NSW 2010, Australia
    Gut 60:350-60. 2011
    ..We wanted to determine whether genetic defects that are relevant for colorectal cancer, such as Msh2 or p53 deficiency, would influence the efficiency of sulindac chemoprevention or increase the side effects...
  5. ncbi How to catch all those mutations--the report of the third Human Variome Project Meeting, UNESCO Paris, May 2010
    Maija R J Kohonen-Corish
    Cancer Research Program, Garvan Institute of Medical Research, St Vincent s Clinical School, University of NSW, Sydney, NSW, Australia
    Hum Mutat 31:1374-81. 2010
    ....
  6. ncbi Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer
    M R J Kohonen-Corish
    Cancer Research Program, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
    Oncogene 26:4435-41. 2007
    ..Furthermore, MCC methylation is significantly associated with a distinct spectrum of precursor lesions, which are suggested to give rise to cancers via the serrated neoplasia pathway...
  7. ncbi Promoter hypermethylation of the O(6)-methylguanine DNA methyltransferase gene and microsatellite instability in metastatic melanoma
    Maija R J Kohonen-Corish
    Cancer Research Program, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
    J Invest Dermatol 126:167-71. 2006
    ..Low MSI was detected in five of 50 metastases (10%) and only one of the five metastases also had MGMT methylation. These results demonstrate that in contrast to some previous reports, these tumors have a low frequency of MSI...
  8. ncbi Gene symbol: MSH2. Disease: Hereditary nonpolyposis colorectal cancer
    R Otway
    John Curtin School of Medical Research, Australian National University, Canberra
    Hum Genet 116:539. 2005
  9. ncbi Gene symbol: MSH2. Disease: Hereditary nonpolyposis colorectal cancer
    R Otway
    John Curtin School of Medical Research, Australian National University, Canberra
    Hum Genet 116:538. 2005
  10. ncbi Gene symbol: MSH2. Disease: Hereditary nonpolyposis colorectal cancer
    R Otway
    John Curtin School of Medical Research, Australian National University, Canberra
    Hum Genet 116:538. 2005
  11. ncbi Gene symbol: MSH2. Disease: Hereditary nonpolyposis colorectal cancer
    R Otway
    John Curtin School of Medical Research, Australian National University, Canberra
    Hum Genet 116:536. 2005
  12. ncbi Gene symbol: MSH2. Disease: Hereditary nonpolyposis colorectal cancer
    R Otway
    John Curtin School of Medical Research, Australian National University, Canberra
    Hum Genet 116:536. 2005
  13. ncbi Gene symbol: MLH1. Disease: Hereditary nonpolyposis colorectal cancer
    R Otway
    John Curtin School of Medical Research, Australian National University, Canberra
    Hum Genet 116:535. 2005
  14. ncbi Gene symbol: MLH1. Disease: Hereditary nonpolyposis colorectal cancer
    R Otway
    John Curtain School of Medical Research, Australian National University, Canberra
    Hum Genet 116:534. 2005
  15. ncbi Low microsatellite instability is associated with poor prognosis in stage C colon cancer
    Maija R J Kohonen-Corish
    Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney NSW 2010, Australia
    J Clin Oncol 23:2318-24. 2005
    ..Therefore, to further define this phenotype, we undertook a detailed analysis of the prognostic significance of MSI-L and loss of MGMT expression in colon cancer...
  16. ncbi Susceptibility of Msh2-deficient mice to inflammation-associated colorectal tumors
    Maija R J Kohonen-Corish
    Department of Medicine, University of Sydney, Sydney, NSW 2006, Australia
    Cancer Res 62:2092-7. 2002
    ..This model of colitis offers opportunities to characterize the different molecular pathways of carcinogenesis operating in chronic colitis...