Nicolas Fossat

Summary

Country: Australia

Publications

  1. ncbi request reprint Alternative usage of Otx2 promoters during mouse development
    Nicolas Fossat
    LBMC, ENS Lyon, IFR128 Lyon Gerland, 69364 Lyon Cedex 07, France
    Dev Dyn 233:154-60. 2005
  2. pmc A new GFP-tagged line reveals unexpected Otx2 protein localization in retinal photoreceptors
    Nicolas Fossat
    IGFL, UMR CNRS 5242 INRA 1237 ENS, IFR128 Lyon Gerland, 46 allee d Italie, 69364 Lyon Cedex 07, France
    BMC Dev Biol 7:122. 2007
  3. pmc Temporal and spatial delineation of mouse Otx2 functions by conditional self-knockout
    Nicolas Fossat
    BMC, UMR CNRS 5161 INRA 1237 ENS, IFR128 Lyon Gerland, 46 allee d Italie, 69364 Lyon Cedex 07, France
    EMBO Rep 7:824-30. 2006
  4. ncbi request reprint Molecular dissection reveals decreased activity and not dominant negative effect in human OTX2 mutants
    Gilles Chatelain
    LBMC, ENS Lyon, IFR128 Lyon Gerland, 46 allee d Italie, 69364, Lyon, Cedex 07, France
    J Mol Med (Berl) 84:604-15. 2006

Collaborators

  • Gilles Chatelain
  • Thomas Lamonerie
  • Gilbert Brun

Detail Information

Publications4

  1. ncbi request reprint Alternative usage of Otx2 promoters during mouse development
    Nicolas Fossat
    LBMC, ENS Lyon, IFR128 Lyon Gerland, 69364 Lyon Cedex 07, France
    Dev Dyn 233:154-60. 2005
    ..The third promoter, which shows no activity in embryonic stem cells and is moderately expressed during embryogenesis, is mostly used in specific areas derived from the rostral part of the neural tube...
  2. pmc A new GFP-tagged line reveals unexpected Otx2 protein localization in retinal photoreceptors
    Nicolas Fossat
    IGFL, UMR CNRS 5242 INRA 1237 ENS, IFR128 Lyon Gerland, 46 allee d Italie, 69364 Lyon Cedex 07, France
    BMC Dev Biol 7:122. 2007
    ..Yet, later expression and functions remain poorly characterized as specific reagents to detect the protein at any stage of development are still missing...
  3. pmc Temporal and spatial delineation of mouse Otx2 functions by conditional self-knockout
    Nicolas Fossat
    BMC, UMR CNRS 5161 INRA 1237 ENS, IFR128 Lyon Gerland, 46 allee d Italie, 69364 Lyon Cedex 07, France
    EMBO Rep 7:824-30. 2006
    ..The transient action of tamoxifen pulses allows time-course mutation. We demonstrate efficient temporal knockout and demarcate spatio-temporal windows in which Otx2 controls the head, brain structures and body development...
  4. ncbi request reprint Molecular dissection reveals decreased activity and not dominant negative effect in human OTX2 mutants
    Gilles Chatelain
    LBMC, ENS Lyon, IFR128 Lyon Gerland, 46 allee d Italie, 69364, Lyon, Cedex 07, France
    J Mol Med (Berl) 84:604-15. 2006
    ..Molecular diagnostic of human mutant OTX2 proteins discriminates hypomorphic and loss of function mutations from other mutations that may not be relevant to ocular pathology...