David I Watson

Summary

Affiliation: Flinders University
Country: Australia

Publications

  1. ncbi Laparoscopic cardiomyotomy and anterior partial fundoplication for achalasia
    R Ackroyd
    Department of Surgery, Royal Adelaide Hospital, University of Adelaide, North Terrace, Adelaide, South Australia 5000, Australia
    Surg Endosc 15:683-6. 2001
  2. ncbi Laparoscopic fundoplication in patients with an aperistaltic esophagus and gastroesophageal reflux
    D I Watson
    Flinders University Department of Surgery, Flinders Medical Center, Bedford Park, South Australia, Australia
    Dis Esophagus 19:94-8. 2006
  3. pmc Accuracy of identification of tissue types in endoscopic esophageal mucosal biopsies used for molecular biology studies
    Plauto Beck
    Department of Surgery
    Clin Exp Gastroenterol 2:1-7. 2009
  4. doi Anterior 90° partial vs Nissen fundoplication--5 year follow-up of a single-centre randomised trial
    David Ian Watson
    Flinders University Department of Surgery, Flinders Medical Centre, Room 3D211, Bedford Park, Adelaide, South Australia 5042, Australia
    J Gastrointest Surg 16:1653-8. 2012
  5. pmc Metallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylation
    Eric Smith
    Department of Surgery, The University of Adelaide, Royal Adelaide Hospital, Adelaide, South Australia, 5005, Australia
    Mol Cancer 4:42. 2005
  6. pmc MicroRNAs, development of Barrett's esophagus, and progression to esophageal adenocarcinoma
    Cameron M Smith
    Department of Surgery, Flinders University, Room 3D211, Flinders Medical Centre, Bedford Park, South Australia 5042, Australia
    World J Gastroenterol 16:531-7. 2010
  7. ncbi Excision of laparoscopic port sites increases the likelihood of wound metastases in an experimental model
    D I Watson
    Department of Surgery, Royal Adelaide Hospital, The University of Adelaide, Adelaide, South Australia 5000, Australia
    Surg Endosc 17:83-5. 2003
  8. ncbi Laparoscopic treatment of gastro-oesophageal reflux disease
    David I Watson
    Department of Surgery, Flinders University, Flinders Medical Centre, Bedford Park, SA 5042, Australia
    Best Pract Res Clin Gastroenterol 18:19-35. 2004
  9. doi Prevalence of symptoms and use of medication for gastroesophageal reflux in an Australian community
    David I Watson
    Department of Surgery, Flinders University, Room 3D211, Flinders Medical Centre, Bedford Park, SA, 5042, Australia
    World J Surg 33:88-94. 2009
  10. ncbi Multicenter, prospective, double-blind, randomized trial of laparoscopic nissen vs anterior 90 degrees partial fundoplication
    David I Watson
    Department of Surgery, k Flinders University of South Australia, Adelaide, Australia
    Arch Surg 139:1160-7. 2004

Collaborators

Detail Information

Publications114 found, 100 shown here

  1. ncbi Laparoscopic cardiomyotomy and anterior partial fundoplication for achalasia
    R Ackroyd
    Department of Surgery, Royal Adelaide Hospital, University of Adelaide, North Terrace, Adelaide, South Australia 5000, Australia
    Surg Endosc 15:683-6. 2001
    ..CONCLUSION: Laparoscopic cardiomyotomy with anterior partial fundoplication achieves excellent symptomatic relief for patients with achalasia, and it can be performed with minimal morbidity...
  2. ncbi Laparoscopic fundoplication in patients with an aperistaltic esophagus and gastroesophageal reflux
    D I Watson
    Flinders University Department of Surgery, Flinders Medical Center, Bedford Park, South Australia, Australia
    Dis Esophagus 19:94-8. 2006
    ..Patients with troublesome reflux and an aperistaltic esophagus can be effectively treated by laparoscopic fundoplication. An acceptable outcome will be achieved in the majority of patients...
  3. pmc Accuracy of identification of tissue types in endoscopic esophageal mucosal biopsies used for molecular biology studies
    Plauto Beck
    Department of Surgery
    Clin Exp Gastroenterol 2:1-7. 2009
    ....
  4. doi Anterior 90° partial vs Nissen fundoplication--5 year follow-up of a single-centre randomised trial
    David Ian Watson
    Flinders University Department of Surgery, Flinders Medical Centre, Room 3D211, Bedford Park, Adelaide, South Australia 5042, Australia
    J Gastrointest Surg 16:1653-8. 2012
    ..This paper reports 5-year follow-up outcomes to determine whether anterior 90° fundoplication achieves a satisfactory longer-term outcome...
  5. pmc Metallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylation
    Eric Smith
    Department of Surgery, The University of Adelaide, Royal Adelaide Hospital, Adelaide, South Australia, 5005, Australia
    Mol Cancer 4:42. 2005
    ....
  6. pmc MicroRNAs, development of Barrett's esophagus, and progression to esophageal adenocarcinoma
    Cameron M Smith
    Department of Surgery, Flinders University, Room 3D211, Flinders Medical Centre, Bedford Park, South Australia 5042, Australia
    World J Gastroenterol 16:531-7. 2010
    ..Understanding altered miRNA expression is likely to help unravel the molecular mechanisms that underpin the development of Barrett's esophagus and its progression to cancer...
  7. ncbi Excision of laparoscopic port sites increases the likelihood of wound metastases in an experimental model
    D I Watson
    Department of Surgery, Royal Adelaide Hospital, The University of Adelaide, Adelaide, South Australia 5000, Australia
    Surg Endosc 17:83-5. 2003
    ..While it has been suggested that this strategy could be used clinically, its efficacy has not been established...
  8. ncbi Laparoscopic treatment of gastro-oesophageal reflux disease
    David I Watson
    Department of Surgery, Flinders University, Flinders Medical Centre, Bedford Park, SA 5042, Australia
    Best Pract Res Clin Gastroenterol 18:19-35. 2004
    ..New endoscopic treatments for reflux will need to achieve similar outcomes before they can replace the laparoscopic approach...
  9. doi Prevalence of symptoms and use of medication for gastroesophageal reflux in an Australian community
    David I Watson
    Department of Surgery, Flinders University, Room 3D211, Flinders Medical Centre, Bedford Park, SA, 5042, Australia
    World J Surg 33:88-94. 2009
    ..In this study we determined the prevalence of symptoms of gastroesophageal reflux and other "esophageal" symptoms, and the consumption of medication for reflux in an Australian community...
  10. ncbi Multicenter, prospective, double-blind, randomized trial of laparoscopic nissen vs anterior 90 degrees partial fundoplication
    David I Watson
    Department of Surgery, k Flinders University of South Australia, Adelaide, Australia
    Arch Surg 139:1160-7. 2004
    ..Laparoscopic anterior 90 degrees partial fundoplication for gastroesophageal reflux is associated with a lower incidence of postoperative dysphagia and other adverse effects compared with laparoscopic Nissen fundoplication...
  11. doi Endoscopic and laparoscopic treatment of gastroesophageal reflux
    David I Watson
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, South Australia 5042, Australia
    Expert Rev Gastroenterol Hepatol 4:235-43. 2010
    ....
  12. doi Evolution and development of surgery for large paraesophageal hiatus hernia
    David I Watson
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, SA, 5042, Australia
    World J Surg 35:1436-41. 2011
    ..More work is required to define the optimal approach to repair of large paraesophageal hiatus hernias...
  13. doi Five-year follow-up of a multicenter, double-blind randomized clinical trial of laparoscopic Nissen vs anterior 90 degrees partial fundoplication
    Rajwinder S Nijjar
    University of Adelaide, Adelaide, South Australia
    Arch Surg 145:552-7. 2010
    ..Laparoscopic 90 degrees anterior partial fundoplication for gastroesophageal reflux disease achieves equivalent results to laparoscopic Nissen fundoplication...
  14. doi Surveillance endoscopy at five or more years after cardiomyotomy for achalasia
    James A Gossage
    Discipline of Surgery, The University of Adelaide, Royal Adelaide Hospital, North Terrace Department of Surgery, Flinders University, Adelaide, South Australia
    Ann Surg 259:464-8. 2014
    ..To perform long-term histopathological and clinical assessment of patients who have previously undergone cardiomyotomy for achalasia...
  15. ncbi Improving the accuracy of TNM staging in esophageal cancer: a pathological review of resected specimens
    Sarah K Thompson
    Discipline of Surgery, University of Adelaide, Adelaide, South Australia, Australia
    Ann Surg Oncol 15:3447-58. 2008
    ..Inclusion of additional information such as the number of metastatic lymph nodes and extracapsular lymph node invasion may improve the current staging system and lead to optimization of patient treatment...
  16. ncbi Recurrent heartburn after laparoscopic fundoplication is not always recurrent reflux
    Sarah K Thompson
    Department of Surgery, University of Adelaide, Level 5, Eleanor Harrald Building, Royal Adelaide Hospital, Adelaide, South Australia 5000, Australia
    J Gastrointest Surg 11:642-7. 2007
    ..A small cohort of patients present after antireflux surgery complaining of recurrent heartburn. Many of these patients have been empirically recommenced on proton pump inhibitors...
  17. doi MicroRNA-143 and -205 expression in neosquamous esophageal epithelium following Argon plasma ablation of Barrett's esophagus
    Willem A Dijckmeester
    Department of Surgery, Flinders University, Room 3D211, Flinders Medical Centre, Bedford Park, South Australia, 5042, Australia
    J Gastrointest Surg 13:846-53. 2009
    ..Investigating simple columnar or stratified squamous epithelium associated cytokeratin and microRNA (miRNA) expression in neo-squamous epithelium could help determine the identity and stability of the neosquamous epithelium...
  18. doi Laparoscopic anterior 90 degree fundoplication for reflux or large hiatus hernia
    Mohammed J Shukri
    Department of Surgery, Flinders University, Flinders Medical Centre, Adelaide, South Australia, Australia
    ANZ J Surg 78:123-7. 2008
    ..The clinical results of laparoscopic anterior 90 degree fundoplication for either reflux or as part of repair of a large hiatus hernia are encouraging, although longer-term follow up is required to confirm durability of reflux control...
  19. ncbi Randomized trial of argon plasma coagulation versus endoscopic surveillance for barrett esophagus after antireflux surgery: late results
    Tim Bright
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, South Australia, UK
    Ann Surg 246:1016-20. 2007
    ..To determine the efficacy of endoscopic argon plasma coagulation (APC) for ablation of Barrett esophagus...
  20. ncbi Quality of life following laparoscopic anterior 90 degrees versus Nissen fundoplication: results from a multicenter randomized trial
    Sean A Woodcock
    Flinders University of South Australia, Adelaide, SA, Australia
    World J Surg 30:1856-63. 2006
    ....
  21. doi Effect of sex on symptoms associated with gastroesophageal reflux
    Zhen Chen
    Department of Surgery, Flinders University, Flinders Medical Centre, Bedford Park, South Australia, Australia
    Arch Surg 146:1164-9. 2011
    ..Previous research suggests that females have a poorer outcome than do males after surgery for gastroesophageal reflux...
  22. ncbi Laparoscopic antireflux surgery in the elderly
    Brechtje A Grotenhuis
    Department of Surgery, Flinders University, Room 3D211, Flinders Medical Centre, Bedford Park, South Australia, 5042, Australia
    Surg Endosc 22:1807-12. 2008
    ..In this study we determined the outcome for laparoscopic antireflux surgery in patients aged 70 years or older, in whom either symptoms of gastroesophageal reflux or a large paraesophageal hernia was the indication for surgery...
  23. ncbi Randomized trial of division versus nondivision of the short gastric vessels during laparoscopic Nissen fundoplication: 10-year outcomes
    Huiqi Yang
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, South Australia
    Ann Surg 247:38-42. 2008
    ..We have previously reported the 6-month and 5-year outcomes from a randomized trial, which have shown no advantages after division of these vessels. In this study, we determined the longer-term (10 years) outcomes from this trial...
  24. pmc miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus
    Cameron M Smith
    Department of Surgery, Flinders University, Bedford Park, South Australia, Australia
    World J Gastroenterol 17:1036-44. 2011
    ..To investigate miR-200 family expression in Barrett's epithelium, gastric and duodenal epithelia, and esophageal adenocarcinoma...
  25. pmc Impact of gastro-oesophageal reflux on microRNA expression, location and function
    Cameron M Smith
    Department of Surgery, Flinders University, Flinders Medical Centre, Bedford Park, SA 5042, Australia
    BMC Gastroenterol 13:4. 2013
    ..Now, to better understand early steps in the initiation of Barrett's oesophagus, we assessed the expression, location and function of these microRNAs in oesophageal squamous mucosa from individuals with ulcerative oesophagitis...
  26. ncbi Ablation of Barrett's oesophagus: towards improved outcomes for oesophageal cancer?
    George C Mayne
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, South Australia, Australia
    ANZ J Surg 82:592-8. 2012
    ..Longer-term outcome data and data from larger cohorts are required to confirm the appropriateness of these procedures...
  27. doi Defining a learning curve for laparoscopic cardiomyotomy
    Brechtje A Grotenhuis
    Department of Surgery, Flinders Medical Centre, Flinders University, Room 3D211, Bedford Park, SA 5042, Australia
    World J Surg 32:1689-94. 2008
    ..This study was designed to determine whether there is a learning curve for laparoscopic cardiomyotomy for the treatment of achalasia...
  28. ncbi Laparoscopic anterior 180 degrees partial fundoplication: five-year results and beyond
    Sam Rice
    Department of Surgery, Flinders University, Flinders Medical Centre, Bedford Park, Australia
    Arch Surg 141:271-5. 2006
    ..Laparoscopic anterior 180 degrees partial fundoplication provides good long-term relief for symptoms of gastroesophageal reflux disease and is associated with few adverse effects...
  29. doi MiRNAs and their association with locoregional staging and survival following surgery for esophageal carcinoma
    Richard Hummel
    Department of Surgery, Flinders University, Bedford Park, SA, Australia
    Ann Surg Oncol 18:253-60. 2011
    ..In this study we evaluated the expression of selected miRNAs and their relationship to tumor stage and survival in patients with locally advanced tumors following esophagectomy...
  30. ncbi Use of antireflux medication after antireflux surgery
    Bas P L Wijnhoven
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, South Australia, 5042, Australia
    J Gastrointest Surg 12:510-7. 2008
    ..This study was aimed to determine the prevalence and underlying reasons for antireflux medication usage in patients after surgery...
  31. doi Prospective randomized trial of argon plasma coagulation ablation versus endoscopic surveillance of Barrett's esophagus in patients treated with antisecretory medication
    Tim Bright
    Flinders University Department of Surgery, Flinders Medical Centre, Room 3D211, Bedford Park 5042, South Australia, Australia
    Dig Dis Sci 54:2606-11. 2009
    ..0 vs. 0.5 cm). Significant regression of Barrett's esophagus follows ablation with APC, although complete regression was achieved in less than half. The role of APC ablation of non-dysplastic Barrett's esophagus remains uncertain...
  32. ncbi Reoperation for dysphagia after cardiomyotomy for achalasia
    Brechtje A Grotenhuis
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, South Australia 5042, Australia
    Am J Surg 194:678-82. 2007
    ..In the current study we evaluated our experience with reoperation following previous cardiomyotomy...
  33. ncbi Laparoscopic Nissen fundoplication with anterior versus posterior hiatal repair: long-term results of a randomized trial
    Bas P L Wijnhoven
    Department of Surgery, Flinders University, Flinders Medical Centre, South Australia, Australia
    Am J Surg 195:61-5. 2008
    ..Postoperative dysphagia in patients after Nissen fundoplication might be related to the technique used for the closure of the esophageal hiatus...
  34. doi Impact of gastro-esophageal reflux on mucin mRNA expression in the esophageal mucosa
    Aafke H C van Roon
    Department of Surgery, Flinders Medical Centre, Flinders University, Room 3D211, Bedford Park, South Australia, 5042, Australia
    J Gastrointest Surg 12:1331-40. 2008
    ..We therefore sought to identify reflux-induced changes in mucin gene expression using a cell line and biopsies from the esophageal mucosa in patients with and without reflux...
  35. doi Recurrent symptoms after fundoplication with a negative pH study--recurrent reflux or functional heartburn?
    Sarah K Thompson
    Discipline of Surgery, University of Adelaide, Adelaide, South Australia, Australia
    J Gastrointest Surg 13:54-60. 2009
    ..The aim of our study is to determine whether these patients have an associated functional disorder or abnormal cytokine activity and to examine the reproducibility of pH testing...
  36. doi Anterior 180-degree partial fundoplication: a 16-year experience with 548 patients
    Zhen Chen
    Department of Surgery, Flinders University, Flinders Medical Centre, Bedford Park, South Australia, Australia
    J Am Coll Surg 212:827-34. 2011
    ..Late clinical outcomes, however, remain uncertain, and outcomes from large series have not been reported...
  37. doi Learning curve for laparoscopic repair of very large hiatal hernia
    Eu Ling Neo
    Flinders University Department of Surgery, Flinders Medical Centre, Room 3D211, Bedford Park, SA, 5042, Australia
    Surg Endosc 25:1775-82. 2011
    ..Laparoscopic repair of a large hiatal hernia is technically challenging. A significant learning curve likely exists that has not been studied to date...
  38. ncbi Preoperative prediction of long-term outcome following laparoscopic fundoplication
    Colm J O'Boyle
    The University of Adelaide Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    ANZ J Surg 72:471-5. 2002
    ..In this study, we sought to establish whether various parameters that can be determined before surgery, can predict the long-term outcome of surgery...
  39. doi Objective outcomes 14 years after laparoscopic anterior 180-degree partial versus nissen fundoplication: results from a randomized trial
    Joris A Broeders
    Discipline of Surgery, University of Adelaide, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    Ann Surg 258:233-9. 2013
    ..To investigate late objective outcomes 14 years after laparoscopic anterior 180-degree partial versus Nissen fundoplication...
  40. ncbi Perioperative risk analysis for acute respiratory distress syndrome after elective oesophagectomy
    Diana J Paul
    University of Adelaide Discipline of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    ANZ J Surg 81:700-6. 2011
    ..Several pre-, intra- and post-operative factors are thought to predispose to its development in the post-oesophagectomy period. The aim of this study was to determine factors predisposing to ARDS in the post-oesophagectomy period...
  41. doi Chemotherapy-induced modification of microRNA expression in esophageal cancer
    Richard Hummel
    Department of Surgery, Flinders University, Beford Park SA, Australia
    Oncol Rep 26:1011-7. 2011
    ..Cisplatin or 5-fluorouracil alter miRNA expression in esophageal cancer cells. IPA suggests that these miRNAs may target molecular pathways involved in cell survival after chemotherapy...
  42. doi Early reoperation after laparoscopic fundoplication: the importance of routine postoperative contrast studies
    Shigeru Tsunoda
    Discipline of Surgery, Royal Adelaide Hospital, University of Adelaide, Adelaide, SA 5000, Australia
    World J Surg 34:79-84. 2010
    ..The necessity for routine postoperative contrast studies following laparoscopic fundoplication for either gastroesophageal reflux disease or paraesophageal hernia is unclear...
  43. doi The effect of obesity on the outcome of laparoscopic antireflux surgery
    Jacob A Chisholm
    Department of Surgery, Flinders Medical Centre, Flinders University, Room 3D211, Bedford Park, South Australia 5042, Australia
    J Gastrointest Surg 13:1064-70. 2009
    ..It is also thought to predispose patients to a poorer clinical outcome following antireflux surgery. This study examined the effect of body mass index (BMI) on clinical outcomes following laparoscopic antireflux surgery...
  44. doi Outcome following surgery for squamous cell carcinoma of the oesophagus
    En Loon C Yong
    Department of Surgery, University of Adelaide, Adelaide, Australia
    ANZ J Surg 79:724-8. 2009
    ..This study was undertaken to determine the outcomes of patients treated for squamous cell carcinoma (SCC) of the oesophagus...
  45. doi Factors associated with postoperative pulmonary morbidity after esophagectomy for cancer
    Urs Zingg
    Discipline of Surgery, University of Adelaide, Adelaide, SA, Australia
    Ann Surg Oncol 18:1460-8. 2011
    ..Changes in technology and treatment such as minimally invasive esophagectomy (MIE) and neoadjuvant treatment mandate analysis of more contemporary cohorts...
  46. doi Prospective randomized trial of laparoscopic Nissen fundoplication with anterior versus posterior hiatal repair: late outcomes
    Carolyn R Chew
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, SA, 5042, Australia
    World J Surg 35:2038-44. 2011
    ..In 1997, we commenced a randomized trial to evaluate the impact of anterior versus posterior hiatal repair techniques on these outcomes. In the present study, we evaluated the 10-year outcomes from this trial...
  47. doi Outcomes for trainees vs experienced surgeons undertaking laparoscopic antireflux surgery - is equipoise achieved?
    Claire N Brown
    Department of Surgery and the Royal Adelaide Hospital, University of Adelaide, Level 5, Eleanor Harrald Building, Royal Adelaide Hospital, 5000 Adelaide, South Australia, Australia
    J Gastrointest Surg 17:1173-80. 2013
    ..It is unclear, however, whether this can be eliminated by supervision of early cases by experienced surgeons. The aim of this study was to evaluate the impact of training under supervision on outcomes for laparoscopic fundoplication...
  48. doi Molecular biomarkers and ablative therapies for Barrett's esophagus
    Jacob A Chisholm
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, South Australia 5042, Australia
    Expert Rev Gastroenterol Hepatol 6:567-81. 2012
    ..Biomarkers could be used to optimize endoscopic surveillance strategies following ablation, but this needs to be assessed by clinical studies and economic modeling...
  49. doi Outcome following management of dysphagia after laparoscopic anti-reflux surgery
    Huiqi Yang
    Flinders University Department of Surgery, Room 3D211, Flinders Medical Centre, Bedford Park, SA, 5042, Australia
    World J Surg 36:838-43. 2012
    ..Some patients develop troublesome dysphagia after laparoscopic antireflux surgery, and a proportion require further intervention. The management of this problem was evaluated...
  50. doi Five-year outcome after laparoscopic anterior partial versus Nissen fundoplication: four randomized trials
    Joris A Broeders
    Discipline of Surgery, University of Adelaide, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    Ann Surg 255:637-42. 2012
    ..To compare longer term (5-year) outcomes for reflux control and postsurgery side effects after laparoscopic anterior (90° and 180°) partial versus Nissen fundoplication for gastroesophageal reflux...
  51. doi Changing work patterns for benign upper gastrointestinal and biliary disease: 1994-2007
    Alexander P M Jay
    Flinders University, Department of Surgery, Flinders Medical Centre, Bedford Park, South Australia, Australia
    ANZ J Surg 80:519-25. 2010
    ..The evolution of surgical technology has impacted on surgical practice. We determined trends in surgical caseload for common benign biliary and upper gastrointestinal conditions in Australia over the last 15 years...
  52. doi Outcome of endoscopy surveillance for Barrett's oesophagus
    Tim Bright
    Department of Surgery, Flinders University, Bedford Park South Australia, Australia
    ANZ J Surg 79:812-6. 2009
    ..Endoscopic surveillance of individuals with Barrett's oesophagus is undertaken to detect early stage oesophageal malignancy. The impact of a surveillance programme on endoscopy resources and disease detection is uncertain...
  53. ncbi Laparoscopic Nissen fundoplication: clinical outcomes at 10 years
    Jamie J Kelly
    Discipline of Surgery, University of Adelaide, Royal Adelaide Hospital, Adelaide, South Australia
    J Am Coll Surg 205:570-5. 2007
    ..Laparoscopic Nissen fundoplication is now the most common operative procedure for treatment of gastroesophageal reflux disease, although longterm clinical outcomes after this procedure remain uncertain...
  54. doi Impact of gender and age on the long-term outcome of laparoscopic fundoplication
    Plauto E Beck
    Department of Surgery, Flinders Medical Centre, Flinders University, Bedford Park, SA, Australia
    World J Surg 33:2620-6. 2009
    ..Therefore, in this study we investigated the impact of gender and age on longer-term clinical outcomes following laparoscopic fundoplication...
  55. doi Mir-148a improves response to chemotherapy in sensitive and resistant oesophageal adenocarcinoma and squamous cell carcinoma cells
    Richard Hummel
    Department of Surgery, Flinders University, Room 3D213, Flinders Medical Centre, 5042 Bedford Park, South Australia, Australia
    J Gastrointest Surg 15:429-38. 2011
    ..Response to chemotherapy varies widely in patients with advanced oesophageal cancer. We investigated the impact of manipulating certain microRNAs on response to cisplatin and 5-fluorouracil (5-FU) in oesophageal cancer cells...
  56. doi Minimally invasive versus open esophagectomy for patients with esophageal cancer
    Urs Zingg
    Department of Surgery, Flinders Medical Centre, Flinders University, South Australia, Australia
    Ann Thorac Surg 87:911-9. 2009
    ..Minimally invasive esophagectomy (MIE) compared with open esophagectomy (OE) has been shown to have clinical advantages, but selection bias is present...
  57. ncbi Esophageal manometry and clinical outcome after laparoscopic Nissen fundoplication
    Huiqi Yang
    Department of Surgery, Flinders University, Room 3D211, Flinders Medical Centre, Bedford Park, Adelaide, SA, Australia
    J Gastrointest Surg 11:1126-33. 2007
    ....
  58. doi The influence on outcome of indications for antireflux surgery
    Urs Zingg
    Discipline of Surgery, University of Adelaide, Eleanor Harrald Building, Adelaide, SA, 5000, Australia
    World J Surg 34:2813-20. 2010
    ..Patients with gastroesophageal reflux referred for fundoplication present with different symptom patterns. Previous studies have not analyzed the clinical outcome after fundoplication in patients stratified according to symptom patterns...
  59. ncbi Gastroenterologists' views of symptoms following laparoscopic fundoplication: anecdotally based medicine?
    Robert Ludemann
    University of Adelaide Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    ANZ J Surg 73:996-9. 2003
    ..A large group of gastroenterologists was surveyed to determine their understanding of the common outcomes of surgical management of GORD...
  60. ncbi Laparoscopic cardiomyotomy for achalasia: long-term outcomes
    Justin R Bessell
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, SA, Australia
    ANZ J Surg 76:558-62. 2006
    ..In addition, we sought to identify preoperative factors predicting a good postoperative outcome...
  61. doi Can miRNA profiling allow us to determine which patients with esophageal cancer will respond to chemoradiotherapy?
    George C Mayne
    Department of Surgery, Flinders University, Bedford Park, SA 5042, Australia
    Expert Rev Anticancer Ther 13:271-3. 2013
    ....
  62. ncbi MicroRNAs and esophageal cancer--implications for pathogenesis and therapy
    George C Mayne
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, South Australia 5042, Australia
    Curr Pharm Des 19:1211-26. 2013
    ..These approaches are producing encouraging results, with one technology in a phase I/IIa clinical trial...
  63. ncbi Chest pain before and after laparoscopic cardiomyotomy for achalasia
    Carolyn Wuller
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, South Australia, Australia
    ANZ J Surg 81:590-4. 2011
    ..However, some patients continue to experience chest pain after surgery, even when symptoms such as dysphagia have resolved. In this study, we quantified chest pain and the impact of myotomy on this symptom...
  64. ncbi Acute ruptured esophageal duplication cyst
    Eu Ling Neo
    Flinders University Department of Surgery, Flinders Medical Centre, Adelaide, South Australia, Australia
    Dis Esophagus 17:109-11. 2004
    ..Conventionally this is achieved via a thoracotomy, however thoracoscopic-assisted excision may have a role...
  65. pmc Division of short gastric vessels at laparoscopic nissen fundoplication: a prospective double-blind randomized trial with 5-year follow-up
    Colm J O'Boyle
    University of Adelaide, Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia
    Ann Surg 235:165-70. 2002
    ..To determine whether division of the short gastric vessels at laparoscopic fundoplication confers long-term clinical benefit to patients...
  66. ncbi Outcome of oesophagectomy for adenocarcinoma of the oesophagus and oesophagogastric junction
    Xun Zhang
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, South Australia, Australia
    ANZ J Surg 75:513-9. 2005
    ....
  67. ncbi Results of laparoscopic antireflux operations in patients who have Barrett's esophagus
    Glyn G Jamieson
    Department of Surgery, University of Adelaide, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia
    Chest Surg Clin N Am 12:149-55. 2002
    ..The authors believe that laparoscopic antireflux surgery is a safe and effective approach for the cure of reflux-related symptoms in patients who have Barrett's esophagus...
  68. ncbi Tumour implantation following laparoscopy using different insufflation gases
    Anurag Gupta
    University of Adelaide Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    ANZ J Surg 72:254-7. 2002
    ..Helium insufflation is also associated with lower rates of intra-abdominal tumour spread. The aim of this study was to determine whether these identified benefits apply to inert gases in general...
  69. ncbi Single center prospective randomized trial of laparoscopic Nissen versus anterior 90 degrees fundoplication
    Gary M Spence
    University of Adelaide Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia
    J Gastrointest Surg 10:698-705. 2006
    ..Anterior 90 degrees fundoplication is followed by fewer side effects than Nissen fundoplication. This advantage is offset by a greater likelihood of reflux recurrence. However, this does not diminish patient satisfaction...
  70. doi Laparoscopic repair of a giant hiatus hernia--how I do it
    Bas P L Wijnhoven
    Department of Surgery, Flinders Medical Centre, Flinders University, Room 3D211, Bedford Park, South Australia, 5042, Australia
    J Gastrointest Surg 12:1459-64. 2008
    ..For this reason, we believe that the mesh should only be used in appropriately designed clinical trials, and for now, the standard approach to laparoscopic repair of a large hiatus hernia is sutured repair...
  71. ncbi Endoscopic stapling for pharyngeal pouch: does it make the cut?
    Ahmad Aly
    University of Adelaide Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    ANZ J Surg 74:116-21. 2004
    ..The aim of the present study was to determine the outcome associated with endoscopic stapling of pharyngeal pouch in an Australian setting...
  72. doi New endoscopic and surgical treatment options for early esophageal adenocarcinoma
    Susan Gan
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, South Australia, Australia
    J Gastroenterol Hepatol 25:1478-84. 2010
    ..Better data are still required to demonstrate improved outcomes from endoscopic treatment and minimally invasive esophagectomy...
  73. pmc MicroRNA-196a & microRNA-101 expression in Barrett's oesophagus in patients with medically and surgically treated gastro-oesophageal reflux
    Sebastien Haiart
    Department of Surgery, Flinders University, Flinders Medical Centre, Room 3D211, Bedford Park, South Australia 5042, Australia
    BMC Res Notes 4:41. 2011
    ..abstract:..
  74. doi Laparoscopic antireflux surgery in patients with throat symptoms: a word of caution
    Dharmendran Ratnasingam
    Department of Surgery, Flinders University, Flinders Medical Centre, Bedford Park, SA, 5042, Australia
    World J Surg 35:342-8. 2011
    ..We evaluated the clinical outcome in these patients and compared their outcomes with a larger group of patients who did not have throat symptoms before fundoplication...
  75. ncbi Use of ethylenediaminetetraacetic acid for in vivo stripping of columnar mucosa: pilot study in an experimental model
    Michael France
    Department of Surgery, University of Adelaide, Royal Adelaide Hospital, Adelaide, Australia
    ANZ J Surg 76:392-7. 2006
    ..Animal experiments that suggest that ethylenediaminetetraacetic acid (EDTA) could be a novel agent for ablation of Barrett's oesophagus are reported in this article...
  76. pmc An evaluation of prognostic factors and tumor staging of resected carcinoma of the esophagus
    Bas P L Wijnhoven
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, South Australia 5042, Australia
    Ann Surg 245:717-25. 2007
    ..To evaluate prognostic factors and tumor staging in patients after esophagectomy for cancer...
  77. pmc Outcome for esophageal cancer following treatment with chemotherapy and radiotherapy but not esophagectomy: Nonsurgical treatment of esophageal cancer
    Urs Zingg
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, South Australia, Australia
    Clin Exp Gastroenterol 2:75-83. 2009
    ..More than 50% of patients with esophageal cancer are not suitable for surgery. The aim of this study was to analyze the outcome of patients undergoing standard nonsurgical treatment...
  78. pmc Improving surveillance for Barrett's oesophagus
    Peter A Bampton
    Department of Gastroenterology and Hepatology, Flinders Medical Centre, Bedford Park, SA 5042, Australia
    BMJ 332:1320-3. 2006
    ..A retrospective audit of surveillance for Barrett's oesophagus 1996-2001 identified the need to improve adherence to guidelines for the endoscopic surveillance of patients with Barrett's oesophagus...
  79. ncbi Laparoscopic Nissen fundoplication: five-year results and beyond
    T Lafullarde
    University of Adelaide Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia 5000, Australia
    Arch Surg 136:180-4. 2001
    ..Laparoscopic Nissen fundoplication provides long-term relief of symptoms of gastroesophageal reflux disease...
  80. ncbi Five-year follow-up of a randomized clinical trial of laparoscopic total versus anterior 180 degrees fundoplication
    R Ludemann
    University of Adelaide Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    Br J Surg 92:240-3. 2005
    ..This paper reports longer-term (5 year) outcomes from that trial...
  81. ncbi Influence of follow-up methodology and completeness on apparent clinical outcome of fundoplication
    Robert Ludemann
    University of Adelaide Department of Surgery, Royal Adelaide Hospital, North Terruce, Adelaide, South Australia 5000, Australia
    Am J Surg 186:143-7. 2003
    ..Mail-out responses, however, are rarely complete, and patients returning mail-out questionnaires might be different from patients who do not return questionnaires...
  82. ncbi Suturing efficiency during hiatal repair for laparoscopic fundoplication
    Eu Ling Neo
    University of Adelaide Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    ANZ J Surg 74:13-7. 2004
    ..The aim of the present project was to develop a method for the objective analysis of a laparoscopic suturing task in the real clinical environment, so that surgeon-in-training performance could be objectively evaluated...
  83. ncbi Esophageal ileus following laparoscopic fundoplication
    J C Myers
    University of Adelaide Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    Dis Esophagus 20:420-7. 2007
    ..Peristalsis improved at 3 months or more following surgery. This suggests that an 'esophageal ileus' occurs during the early period after laparoscopic fundoplication...
  84. ncbi A prospective randomized trial of laparoscopic Nissen fundoplication with anterior vs posterior hiatal repair
    D I Watson
    University of Adelaide, Department of Surgery, Royal Adelaide Hospital, South Australia 5000, Australia
    Arch Surg 136:745-51. 2001
    ..The technique used for repair of the esophageal hiatus during laparoscopic Nissen fundoplication can influence the likelihood of postoperative dysphagia...
  85. doi Ten-year clinical outcome of a prospective randomized clinical trial of laparoscopic Nissen versus anterior 180( degrees ) partial fundoplication
    W Cai
    Flinders University Department of Surgery, Flinders Medical Centre, Bedford Park, Australia
    Br J Surg 95:1501-5. 2008
    ..This study evaluated clinical outcomes after 10 years...
  86. doi Long-term outcomes of revisional surgery following laparoscopic fundoplication
    P J Lamb
    University of Adelaide Discipline of Surgery, Royal Adelaide Hospital, South Australia, Australia
    Br J Surg 96:391-7. 2009
    ..A small proportion of patients who have laparoscopic antireflux procedures require revisional surgery. This study investigated long-term clinical outcomes...
  87. ncbi Complications of laparoscopic antireflux surgery
    D I Watson
    Department of Surgery, University of Adelaide, Royal Adelaide Hospital, Adelaide, South Australia 5000, Australia
    Surg Endosc 15:344-52. 2001
    ..For this reason, the surgeon should have a low threshold for early laparoscopic reexploration, facilitated by early radiological contrast studies, in order to reduce the likelihood that problems will arise later...
  88. ncbi Outcome of laparoscopic anterior 180-degree partial fundoplication for gastroesophageal reflux disease
    D I Watson
    University of Adelaide Department of Surgery and Royal Adelaide Hospital, Adelaide, South Australia, Australia
    J Gastrointest Surg 4:486-92. 2000
    ..Laparoscopic anterior partial fundoplication is an effective operation for gastroesophageal reflux, with a low incidence of side effects and a good overall outcome...
  89. ncbi Laparoscopic fundoplication for patients with symptoms but no objective evidence of gastroesophageal reflux
    P C Leeder
    The University of Adelaide, Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia
    Dis Esophagus 15:309-14. 2002
    ..Carefully selected patients with typical reflux symptoms can have a good outcome. However, patients who do not have typical symptoms and who respond poorly to acid suppression are not likely to benefit from surgery...
  90. ncbi Obesity and its effect on outcome of laparoscopic Nissen fundoplication
    J Fraser
    University of Adelaide Department of Surgery, Royal Adelaide Hospital, South Australia, Australia
    Dis Esophagus 14:50-3. 2001
    ..There was a slight trend toward less satisfaction with the surgical outcome in patients of normal weight. Preoperative obesity is not associated with a poorer outcome following laparoscopic Nissen fundoplication...
  91. ncbi A further modification of fundoplication. 90 degrees anterior fundoplication
    R J Krysztopik
    University of Adelaide, Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia 5000, Australia
    Surg Endosc 16:1446-51. 2002
    ..To reduce the likelihood of side effects, we have progressively modified this procedure to an anterior 90 degrees partial fundoplication...
  92. ncbi Helium and other alternative insufflation gases for laparoscopy
    S J Neuhaus
    Department of Surgery, The University of Adelaide, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia 5000, Australia
    Surg Endosc 15:553-60. 2001
    ..CONCLUSIONS: Although the use of alternative gases appears to be promising, further evaluation is needed within both clinical and laboratory settings before their routine clinical use can be supported...
  93. ncbi Role of fundoplication in patient symptomatology after laparoscopic antireflux surgery
    A C de Beaux
    Department of Surgery, Level 5 Eleanor Harrald Building, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia, Australia
    Br J Surg 88:1117-21. 2001
    ..Symptoms following antireflux surgery are often seen as unavoidable sequelae of the operation. The aims were to determine the frequency of new adverse sequelae following antireflux surgery and the preoperative incidence of similar symptoms...
  94. ncbi Prospective randomized controlled trial of argon plasma coagulation ablation vs. endoscopic surveillance of patients with Barrett's esophagus after antireflux surgery
    Roger Ackroyd
    University of Adelaide, Department of Surgery and Gastroenterology Unit, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia, Australia
    Gastrointest Endosc 59:1-7. 2004
    ..This study assessed the efficacy and safety of argon plasma coagulation in the ablation of Barrett's esophagus in patients who have undergone antireflux surgery...
  95. ncbi Laparoscopic placement of peritoneal dialysis catheters: 7 years experience
    Cu T Lu
    The University of Adelaide, Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    ANZ J Surg 73:109-11. 2003
    ..The purpose of this study was to determine the long-term outcome of this approach...
  96. ncbi Efficacy of cytotoxic agents for the prevention of laparoscopic port-site metastases
    S J Neuhaus
    The Royal Adelaide Centre for Endoscopic Surgery, Royal Adelaide Hospital, Australia
    Arch Surg 133:762-6. 1998
    ..This study investigated in an experimental model the influence of cytotoxic agents (administered intraperitoneally or intramuscularly) on the development of port-site metastases following laparoscopic surgery...
  97. ncbi Metabolic and immunologic consequences of laparoscopy with helium or carbon dioxide insufflation: a randomized clinical study
    S J Neuhaus
    University of Adelaide, Department of Surgery, Royal Adelaide Hospital, South Australia, Australia
    ANZ J Surg 71:447-52. 2001
    ..The outcomes of the present study, however, are different to those obtained from previous laboratory studies and further research is needed to confirm this outcome...
  98. ncbi Diaphragmatic hernia after minimally invasive esophagectomy
    A Aly
    University of Adelaide Department of Surgery, Royal Adelaide Hospital, Adelaide, Australia
    Dis Esophagus 17:183-6. 2004
    ..We report such a case presenting with features of small bowel obstruction. The paucity of adhesions following the combined laparoscopic and thoracoscopic approach may confer an increased risk of this complication...
  99. ncbi Laparoscopic repair of large hiatal hernias
    A Aly
    Department of Surgery, University of Adelaide, Royal Adelaide Hospital, Adelaide, South Australia
    Br J Surg 92:648-53. 2005
    ..This study evaluated the long-term outcome of laparoscopic repair of large hiatal hernias...
  100. ncbi Helium vs carbon dioxide gas insufflation with or without saline lavage during laparoscopy
    C J O'Boyle
    University of Adelaide, Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia 5000, Australia
    Surg Endosc 16:620-5. 2002
    ....
  101. ncbi Effect of laparoscopy on immune function
    A Gupta
    University of Adelaide Department of Surgery, Royal Adelaide Hospital, Adelaide, South Australia 5000, Australia
    Br J Surg 88:1296-306. 2001
    ..This feature may be clinically important and should be acknowledged when considering laparoscopic surgery in patients with malignancy or sepsis...