D P Chew
Affiliation: Flinders University
- Bivalirudin in percutaneous coronary interventionSam J Lehman
Department of Medicine, Flinders University, South Australia, Australia
Vasc Health Risk Manag 2:357-63. 2006..There are now data from multiple clinical trials and meta-analyses in the setting of ACS and PCI. Early results from the acute catheterization and urgent intervention strategy (ACUITY) trial are discussed...
- Impact of a regionalised clinical cardiac support network on mortality among rural patients with myocardial infarctionPhilip A Tideman
Country Health, Adelaide, SA, Australia
Med J Aust 200:157-60. 2014..To evaluate the impact of the regionalised Integrated Cardiovascular Clinical Network (ICCNet) on 30-day mortality among patients with myocardial infarction (MI) in an Australian rural setting...
- Acute coronary syndrome care across Australia and New Zealand: the SNAPSHOT ACS studyDerek P Chew
Department of Cardiovascular Medicine, Flinders University, Adelaide, SA
Med J Aust 199:185-91. 2013..To characterise management of suspected acute coronary syndrome (ACS) in Australia and New Zealand, and to assess the application of recommended therapies according to published guidelines...
- Perceived risk of ischemic and bleeding events in acute coronary syndromesDerek P Chew
Department of Cardiology, Flinders University, Flinders Medical Centre, Adelaide, SA 5042, Australia
Circ Cardiovasc Qual Outcomes 6:299-308. 2013..Acute coronary syndrome registries report the use of incomplete guideline therapies, especially among the highest risk patients. Whether this treatment gap results from misperceptions of risk by physicians is uncertain...
- Patterns of inflammatory activation associated with precipitants of acute coronary syndromes: a case-crossover studyD P Chew
Flinders University Flinders Medical Centre, Adelaide, South Australia, Australia
Intern Med J 42:1096-103. 2012..We sought to assess a broad array of possible precipitants of acute coronary syndromes (ACS) and evaluate their association with detectable inflammatory activation...
- Long-term antiplatelet therapy: from clinical trials to clinical applicationDerek P Chew
Flinders University, Adelaide, South Australia, Australia
Curr Opin Cardiol 27:347-54. 2012..This review seeks to describe the emerging clinical trial data that informs clinical practice with regards to dual antiplatelet therapy...
- The value of "more" information: the emerging role of novel diagnostic investigations in cardiovascular medicineDerek P Chew
Flinders University, Flinders Medical Centre, Flinders Drive, Bedford Park, South Australia 5042, Australia
Heart Lung Circ 18:114-7. 2009..To date many studies in this area have fallen short of demonstrating such benefits and it is our responsibility as a clinical community to demand more of such innovation...
- Randomized trials of clinical networks in the management of ST-elevation MI: can they be performed?Derek P Chew
Flinders University, Flinders Medical Centre, South Australia, Australia
Curr Opin Cardiol 24:301-6. 2009..It is well established that the temporal window during which myocardial salvage may be achieved is limited...
- Potential survival gains in the treatment of myocardial infarctionD P Chew
Flinders University, Flinders Drive, Bedford Park, South Australia, 5042 Australia
Heart 95:1844-50. 2009..To evaluate the potential impact of complete implementation of guideline recommendations in myocardial infarction (MI) care, and contrast this with new innovations...
- Cost effectiveness of a general practice chronic disease management plan for coronary heart disease in AustraliaDerek P Chew
Flinders Medical Centre, Flinders University, Flinders Drive, Bedford Park, SA 5042, Australia
Aust Health Rev 34:162-9. 2010..The cost effectiveness of a general practice-based program for managing coronary heart disease (CHD) patients in Australia remains uncertain. We have explored this through an economic model...
- Six-month survival benefits associated with clinical guideline recommendations in acute coronary syndromesD P Chew
Department of Cardiovascular Medicine, Flinders University, Adelaide, South Australia, Australia
Heart 96:1201-6. 2010..The authors sought to define which guideline-advocated therapies are associated with the greatest benefit with respect to 6-month survival in patients hospitalised with an acute coronary syndrome (ACS)...
- The last mile: improving patient outcomes within modern cardiovascular medicineDerek P Chew
Roy and Marjorie Edwards National Heart Foundation, Adelaide, SA, Australia
Heart Lung Circ 17:S10-3. 2008..This article will discuss some of issues faced in operationalizing "clinical effectiveness" in cardiovascular care in Australia...
- Invasive management and late clinical outcomes in contemporary Australian management of acute coronary syndromes: observations from the ACACIA registryDerek P Chew
Flinders University, Adelaide, SA
Med J Aust 188:691-7. 2008..To describe the impact of invasive management on 12-month survival among patients with suspected acute coronary syndrome (ACS) in Australia...
- National data elements for the clinical management of acute coronary syndromesDerek P B Chew
Flinders Medical Centre, Bedford Park, Adelaide, SA 5042, Australia
Med J Aust 182:S1-14. 2005....
- Clinical end point definitions after percutaneous coronary intervention and their relationship to late mortality: an assessment by attributable riskD P Chew
Flinders University, Adelaide, South Australia, Australia
Heart 92:945-50. 2006..To explore the relative and absolute risks associated with various definitions for myocardial infarction, bleeding and revascularisation within the context of percutaneous coronary intervention (PCI)...
- Bivalirudin versus heparin and glycoprotein IIb/IIIa inhibition among patients with renal impairment undergoing percutaneous coronary intervention (a subanalysis of the REPLACE-2 trial)Derek P Chew
Department of Cardiovascular Medicine, Flinders Medical Centre, Bedford Park, South Australia, Australia
Am J Cardiol 95:581-5. 2005..The safety and efficacy of bivalirudin compared with heparin and planned glycoprotein IIb/IIIa inhibition in this high-risk group are comparable and consistent with the results of the overall trial...
- Morbidity, mortality and economic burden of renal impairment in cardiac intensive careD P Chew
Flinders University, South Australia, Australia
Intern Med J 36:185-92. 2006..Moderate to severe impairment of renal function has emerged as a potent risk factor for adverse short- and long-term outcomes among patients presenting with cardiac disease...
- Current management of acute coronary syndromes in Australia: observations from the acute coronary syndromes prospective auditD P Chew
Department of Cardiology, Flinders University, Flinders Medical Centre, Adelaide, South Australia
Intern Med J 37:741-8. 2007..However, most of these data have been acquired outside the local context. We sought to describe the current patterns of ACS care in Australia...
- Patients with non-ST-elevation acute coronary syndromes undergoing coronary artery bypass grafting in the modern era of antithrombotic therapyDerek P Chew
Flinders Medical Centre, South Australia, Adelaide, Australia
Am Heart J 155:239-44. 2008..We explored the clinical outcomes among high-risk patients undergoing CABG and the impact of modern pharmacology...
- Coronary artery bypass surgery in patients with acute coronary syndromes is difficult to predictDerek P Chew
Flinders Medical Centre, Adelaide, Australia
Am Heart J 155:841-7. 2008..We assessed the ability to predict need for CABG from demographics known at the time of ACS presentation, using data from SYNERGY...
- Improving the management of acute coronary syndromes in Australia: translating evidence to outcomesL T Huynh
Department of Medicine, Cardiovascular Outcomes Research Group and Flinders Centre for Clinical Change and Healthcare Research, Flinders University, Adelaide, South Australia
Intern Med J 37:412-5. 2007..This article reviews what we have learnt from previous quality improvement initiatives and discusses what we need to know to improve acute coronary syndromes management in Australia...
- Impact of age, gender and indigenous status on access to diagnostic coronary angiography for patients presenting with non-ST segment elevation acute coronary syndromes in AustraliaY L Roe
School of Health Sciences, University of South Australia, Adelaide, Australia
Intern Med J 43:317-22. 2013..Indigenous patients are younger and have poorer risk profiles, and represent a group that would benefit from greater investment in prevention strategies...
- The foundation and launch of the Melbourne Interventional Group: a collaborative interventional cardiology projectA E Ajani
Department of Cardiology, Royal Melbourne Hospital, Melbourne, Australia
Heart Lung Circ 15:44-7. 2006..The eventual goal of MIG is to provide a contemporary appraisal of Australian interventional cardiology practice, with opportunities to improve in-hospital and long-term outcomes of patients with coronary artery disease...
- Reperfusion therapy in the acute management of ST-segment-elevation myocardial infarction in Australia: findings from the ACACIA registryLuan T Huynh
Flinders University, Adelaide, SA, Australia
Med J Aust 193:496-501. 2010..To describe the contemporary management and outcomes of patients presenting with ST-segment-elevation myocardial infarction (STEMI) in Australia...
- Cost-effectiveness of drug-eluting stents: if only all things were equalDerek P B Chew
Med J Aust 182:376-7. 2005..They reduce rates of restenosis but not mortality or infarction--so are they worth it?..