B A Kunz

Summary

Affiliation: Deakin University
Country: Australia

Publications

  1. ncbi request reprint Inhibitors of thymine nucleotide biosynthesis: antimetabolites that provoke genetic change via primary non-DNA targets
    B A Kunz
    School of Biological and Chemical Sciences, Deakin University, Geelong, Victoria, Australia
    Mutat Res 355:129-40. 1996
  2. ncbi request reprint Components of nucleotide excision repair and DNA damage tolerance in Arabidopsis thaliana
    Bernard A Kunz
    School of Biological and Chemical Sciences, Deakin University, Geelong, Victoria, Australia
    Environ Mol Mutagen 45:115-27. 2005
  3. ncbi request reprint DNA damage-induced mutation: tolerance via translesion synthesis
    B A Kunz
    School of Biological and Chemical Sciences, Deakin University, Victoria 3217, Geelong, Australia
    Mutat Res 451:169-85. 2000
  4. ncbi request reprint Differences in the mutational specificities of sunlight and UVB radiation suggest a role for transversion-inducing DNA damage in solar photocarcinogenesis
    B A Kunz
    School of Biological and Chemical Sciences, Deakin University, Geelong, Victoria, Australia
    Mutat Res 422:77-83. 1998
  5. ncbi request reprint Defects in base excision repair combined with elevated intracellular dCTP levels dramatically reduce mutation induction in yeast by ethyl methanesulfonate and N-methyl-N'-nitro-N-nitrosoguanidine
    B A Kunz
    School of Biological and Chemical Sciences, Deakin University, Geelong, Victoria, Australia
    Environ Mol Mutagen 32:173-8. 1998
  6. pmc DNA sequence analysis of spontaneous mutagenesis in Saccharomyces cerevisiae
    B A Kunz
    School of Biological and Chemical Sciences, Deakin University, Geelong, Victoria, Australia
    Genetics 148:1491-505. 1998
  7. doi request reprint Arabidopsis thaliana Y-family DNA polymerase eta catalyses translesion synthesis and interacts functionally with PCNA2
    Heather J Anderson
    School of Life and Environmental Sciences, Deakin University, Geelong, VIC 3217, Australia
    Plant J 55:895-908. 2008
  8. ncbi request reprint Detection of Arabidopsis thaliana AtRAD1 cDNA variants and assessment of function by expression in a yeast rad1 mutant
    Edward J Vonarx
    School of Biological and Chemical Sciences, Deakin University, Geelong, VIC 3217, Australia
    Gene 296:1-9. 2002
  9. ncbi request reprint Arabidopsis homologue of human transcription factor IIH/nucleotide excision repair factor p44 can function in transcription and DNA repair and interacts with AtXPD
    Edward J Vonarx
    School of Life and Environmental Sciences, Deakin University, Geelong, Victoria 3217, Australia
    Plant J 46:512-21. 2006
  10. pmc UV-induced DNA damage promotes resistance to the biotrophic pathogen Hyaloperonospora parasitica in Arabidopsis
    Bernard A Kunz
    School of Life and Environmental Sciences, Deakin University, Geelong, Victoria 3217, Australia
    Plant Physiol 148:1021-31. 2008

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Inhibitors of thymine nucleotide biosynthesis: antimetabolites that provoke genetic change via primary non-DNA targets
    B A Kunz
    School of Biological and Chemical Sciences, Deakin University, Geelong, Victoria, Australia
    Mutat Res 355:129-40. 1996
    ..These agents induce genetic change not by attacking DNA, but by interfering with the control of DNA precursor metabolism. This review surveys the genetic effects attributable to selected representatives of this class of antimetabolites...
  2. ncbi request reprint Components of nucleotide excision repair and DNA damage tolerance in Arabidopsis thaliana
    Bernard A Kunz
    School of Biological and Chemical Sciences, Deakin University, Geelong, Victoria, Australia
    Environ Mol Mutagen 45:115-27. 2005
    ....
  3. ncbi request reprint DNA damage-induced mutation: tolerance via translesion synthesis
    B A Kunz
    School of Biological and Chemical Sciences, Deakin University, Victoria 3217, Geelong, Australia
    Mutat Res 451:169-85. 2000
    ..In this article, we review and link the evidence for translesion synthesis in yeast, and the involvement of nonreplicative DNA polymerases, to recent findings in mammalian cells...
  4. ncbi request reprint Differences in the mutational specificities of sunlight and UVB radiation suggest a role for transversion-inducing DNA damage in solar photocarcinogenesis
    B A Kunz
    School of Biological and Chemical Sciences, Deakin University, Geelong, Victoria, Australia
    Mutat Res 422:77-83. 1998
    ..The relevance of these findings to skin cancer is discussed...
  5. ncbi request reprint Defects in base excision repair combined with elevated intracellular dCTP levels dramatically reduce mutation induction in yeast by ethyl methanesulfonate and N-methyl-N'-nitro-N-nitrosoguanidine
    B A Kunz
    School of Biological and Chemical Sciences, Deakin University, Geelong, Victoria, Australia
    Environ Mol Mutagen 32:173-8. 1998
    ..In addition, the results point to a role for AP sites in the production of some EMS- and MNNG-induced G x C --> A x T transitions as well as other substitutions in the dcd1 strain...
  6. pmc DNA sequence analysis of spontaneous mutagenesis in Saccharomyces cerevisiae
    B A Kunz
    School of Biological and Chemical Sciences, Deakin University, Geelong, Victoria, Australia
    Genetics 148:1491-505. 1998
    ..The implications of selected aspects of the data are considered with respect to the mechanisms of spontaneous mutagenesis...
  7. doi request reprint Arabidopsis thaliana Y-family DNA polymerase eta catalyses translesion synthesis and interacts functionally with PCNA2
    Heather J Anderson
    School of Life and Environmental Sciences, Deakin University, Geelong, VIC 3217, Australia
    Plant J 55:895-908. 2008
    ..These observations indicate that AtPoleta can catalyse TLS past UV-induced DNA damage, and links the biological activity of AtPoleta in UV-irradiated cells to PCNA2 and PCNA- and ubiquitin-binding motifs in AtPoleta...
  8. ncbi request reprint Detection of Arabidopsis thaliana AtRAD1 cDNA variants and assessment of function by expression in a yeast rad1 mutant
    Edward J Vonarx
    School of Biological and Chemical Sciences, Deakin University, Geelong, VIC 3217, Australia
    Gene 296:1-9. 2002
    ..These results suggest that alternative splicing may modulate the levels of functional AtRad1 protein...
  9. ncbi request reprint Arabidopsis homologue of human transcription factor IIH/nucleotide excision repair factor p44 can function in transcription and DNA repair and interacts with AtXPD
    Edward J Vonarx
    School of Life and Environmental Sciences, Deakin University, Geelong, Victoria 3217, Australia
    Plant J 46:512-21. 2006
    ..Our results indicate that AtGTF2H2 can act in transcription and NER, and suggest that it participates in both processes in Arabidopsis as part of TFIIH...
  10. pmc UV-induced DNA damage promotes resistance to the biotrophic pathogen Hyaloperonospora parasitica in Arabidopsis
    Bernard A Kunz
    School of Life and Environmental Sciences, Deakin University, Geelong, Victoria 3217, Australia
    Plant Physiol 148:1021-31. 2008
    ..They also suggest UV treatment can circumvent the requirement for recognition of H. parasitica molecules by Arabidopsis proteins to activate an immune response...
  11. ncbi request reprint Plant responses to UV radiation and links to pathogen resistance
    Bernard A Kunz
    School of Life and Environmental Sciences, Deakin University, Geelong, Victoria 3217, Australia
    Int Rev Cytol 255:1-40. 2006
    ..Indeed, pathogen resistance can be enhanced by UV treatment, and recent experiments suggest DNA damage and its processing may have a role...
  12. doi request reprint Age and exposure to arsenic alter base excision repair transcript levels in mice
    Megan J Osmond
    School of Life and Environmental Sciences, Deakin University, Pigdons Road, Geelong, Victoria 3217, Australia
    Mutagenesis 25:517-22. 2010
    ..Reduction of BER transcript levels in 24-week-old mice exposed to As for 2 weeks suggests As may potentiate sensitivity to itself in older animals...