Peter A Dargaville

Summary

Country: Australia

Publications

  1. ncbi request reprint Blood aspiration syndrome as a cause of respiratory distress in the newborn infant
    Emma Gordon
    Department of Neonatology and Murdoch Children s Research Institute, Royal Children s Hospital, Melbourne, Australia
    J Pediatr 142:200-2. 2003
  2. ncbi request reprint Innovation in surfactant therapy I: surfactant lavage and surfactant administration by fluid bolus using minimally invasive techniques
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital, University of Tasmania and Neonatal Respiratory Group, Menzies Research Institute Tasmania, Hobart, TAS, Australia
    Neonatology 101:326-36. 2012
  3. pmc Respiratory support in meconium aspiration syndrome: a practical guide
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital and University of Tasmania, Hobart, TAS 7000, Australia
    Int J Pediatr 2012:965159. 2012
  4. doi request reprint Continuous positive airway pressure failure in preterm infants: incidence, predictors and consequences
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital and University of Tasmania, Hobart, TAS, Australia
    Neonatology 104:8-14. 2013
  5. doi request reprint Fluid recovery during lung lavage in meconium aspiration syndrome
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital and University of Tasmania, Hobart, TAS, Australia
    Acta Paediatr 102:e90-3. 2013
  6. ncbi request reprint Minimally-invasive surfactant therapy in preterm infants on continuous positive airway pressure
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital, Liverpool Street, Hobart TAS 7000, Australia
    Arch Dis Child Fetal Neonatal Ed 98:F122-6. 2013
  7. doi request reprint Lung protective ventilation in extremely preterm infants
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia
    J Paediatr Child Health 48:740-6. 2012
  8. ncbi request reprint Comparison of four methods of lung volume recruitment during high frequency oscillatory ventilation
    Anastasia Pellicano
    Department of Neonatology, Royal Children s Hospital, Melbourne, Australia
    Intensive Care Med 35:1990-8. 2009
  9. doi request reprint Regional tidal ventilation and compliance during a stepwise vital capacity manoeuvre
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital and University of Tasmania, Liverpool Street, Hobart, TAS, 7000, Australia
    Intensive Care Med 36:1953-61. 2010
  10. doi request reprint Randomized controlled trial of lung lavage with dilute surfactant for meconium aspiration syndrome
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital and University of Tasmania, Hobart, Australia
    J Pediatr 158:383-389.e2. 2011

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Blood aspiration syndrome as a cause of respiratory distress in the newborn infant
    Emma Gordon
    Department of Neonatology and Murdoch Children s Research Institute, Royal Children s Hospital, Melbourne, Australia
    J Pediatr 142:200-2. 2003
    ..Blood aspiration syndrome is a distinct diagnostic entity that can result in significant respiratory distress in the neonate...
  2. ncbi request reprint Innovation in surfactant therapy I: surfactant lavage and surfactant administration by fluid bolus using minimally invasive techniques
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital, University of Tasmania and Neonatal Respiratory Group, Menzies Research Institute Tasmania, Hobart, TAS, Australia
    Neonatology 101:326-36. 2012
    ..We are now commencing large-scale clinical trials of this method in preterm infants on CPAP...
  3. pmc Respiratory support in meconium aspiration syndrome: a practical guide
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital and University of Tasmania, Hobart, TAS 7000, Australia
    Int J Pediatr 2012:965159. 2012
    ..With judicious use of available modes of ventilation and adjunctive therapies, infants with even the most severe MAS can usually be supported through the disease, with an acceptably low risk of short- and long-term morbidities...
  4. doi request reprint Continuous positive airway pressure failure in preterm infants: incidence, predictors and consequences
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital and University of Tasmania, Hobart, TAS, Australia
    Neonatology 104:8-14. 2013
    ..Some infants treated in this way ultimately fail on CPAP and require intubation and ventilation...
  5. doi request reprint Fluid recovery during lung lavage in meconium aspiration syndrome
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital and University of Tasmania, Hobart, TAS, Australia
    Acta Paediatr 102:e90-3. 2013
    ..Mean recovery of instilled lavage fluid was 46%, with greater fluid return associated with lower mean airway pressure at 24 h and a shorter duration of respiratory support...
  6. ncbi request reprint Minimally-invasive surfactant therapy in preterm infants on continuous positive airway pressure
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital, Liverpool Street, Hobart TAS 7000, Australia
    Arch Dis Child Fetal Neonatal Ed 98:F122-6. 2013
    ..To evaluate the applicability and potential effectiveness of a technique of minimally-invasive surfactant therapy (MIST) in preterm infants on continuous positive airway pressure (CPAP)...
  7. doi request reprint Lung protective ventilation in extremely preterm infants
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia
    J Paediatr Child Health 48:740-6. 2012
    ..From a practical perspective, this means setting positive end-expiratory pressure at the lowest value that maintains oxygenation and restricting tidal volume using a volume-targeted mode of ventilation...
  8. ncbi request reprint Comparison of four methods of lung volume recruitment during high frequency oscillatory ventilation
    Anastasia Pellicano
    Department of Neonatology, Royal Children s Hospital, Melbourne, Australia
    Intensive Care Med 35:1990-8. 2009
    ..To compare four methods of volume recruitment upon initiation of high frequency oscillatory ventilation (HFOV)...
  9. doi request reprint Regional tidal ventilation and compliance during a stepwise vital capacity manoeuvre
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital and University of Tasmania, Liverpool Street, Hobart, TAS, 7000, Australia
    Intensive Care Med 36:1953-61. 2010
    ..To determine whether, during mechanical ventilation, an optimal positive end-expiratory pressure (PEEP) can be identified by measurement of regional tidal volume and compliance [V (T(reg)), C (RS(reg))]...
  10. doi request reprint Randomized controlled trial of lung lavage with dilute surfactant for meconium aspiration syndrome
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital and University of Tasmania, Hobart, Australia
    J Pediatr 158:383-389.e2. 2011
    ..To evaluate whether lung lavage with surfactant changes the duration of mechanical respiratory support or other outcomes in meconium aspiration syndrome (MAS)...
  11. doi request reprint Refining the method of therapeutic lung lavage in meconium aspiration syndrome
    Peter A Dargaville
    Neonatal Research Group, Murdoch Children s Research Institute, University of Melbourne, Melbourne, Victoria, Australia
    Neonatology 94:160-3. 2008
    ..Therapeutic lung lavage is an emerging treatment for meconium aspiration syndrome (MAS), but the ideal fluid volume and lavage technique remain unclear...
  12. ncbi request reprint Therapeutic lung lavage in meconium aspiration syndrome: a preliminary report
    Peter A Dargaville
    Department of Neonatology, Royal Children s Hospital, Melbourne, Victoria, Australia
    J Paediatr Child Health 43:539-45. 2007
    ..To explore the effects of a large volume lung lavage procedure in ventilated infants with meconium aspiration syndrome...
  13. doi request reprint Preliminary evaluation of a new technique of minimally invasive surfactant therapy
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital and University of Tasmania, Hobart, Australia
    Arch Dis Child Fetal Neonatal Ed 96:F243-8. 2011
    ....
  14. ncbi request reprint The epidemiology of meconium aspiration syndrome: incidence, risk factors, therapies, and outcome
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital, Hobart, Australia
    Pediatrics 117:1712-21. 2006
    ..We sought to examine, in a large cohort of infants within a definable population of live births, the incidence, risk factors, treatments, complications, and outcomes of meconium aspiration syndrome (MAS)...
  15. ncbi request reprint Surfactant therapy for meconium aspiration syndrome: current status
    Peter A Dargaville
    Department of Paediatrics, Royal Hobart Hospital, Hobart, Tasmania, Australia
    Drugs 65:2569-91. 2005
    ..Several randomised controlled trials of surfactant lavage in MAS are underway, and until the results are known, lavage must be considered an unproven and experimental therapy...
  16. doi request reprint Indicators of optimal lung volume during high-frequency oscillatory ventilation in infants
    David G Tingay
    Neonatal Research, Murdoch Childrens Research Institute, Melbourne, Victoria, Australia
    Crit Care Med 41:237-44. 2013
    ....
  17. doi request reprint The effect of suction method, catheter size, and suction pressure on lung volume changes during endotracheal suction in piglets
    Beverley Copnell
    Neonatal Research, Murdoch Childrens Research Institute, Melbourne, Victoria 3052, Australia
    Pediatr Res 66:405-10. 2009
    ..With commonly used suction pressures and catheter sizes, closed suction has no advantage in preventing loss of volume in this animal model...
  18. ncbi request reprint Therapeutic lung lavage in the piglet model of meconium aspiration syndrome
    Peter A Dargaville
    Department of Neonatology, Royal Children s Hospital, Flemington Road, Parkville, VIC 3052, Australia
    Am J Respir Crit Care Med 168:456-63. 2003
    ..Dilute surfactant lavage using two 15-ml/kg aliquots is an effective therapy in the piglet model of meconium aspiration, and should be evaluated in human infants with this condition...
  19. ncbi request reprint A comparison of the effectiveness of open and closed endotracheal suction
    Beverley Copnell
    Royal Children s Hospital, Department of Neonatology, Flemington Rd, VIC 3052, Parkville, Australia
    Intensive Care Med 33:1655-62. 2007
    ..To compare the effectiveness of open and closed endotracheal suction in recovering thin and thick secretions in normal and injured lungs during conventional and high frequency ventilation...
  20. doi request reprint The effects of closed endotracheal suction on ventilation during conventional and high-frequency oscillatory ventilation
    Nicholas J Kiraly
    Neonatal Research, Murdoch Childrens Research Institute, Parkville, Victoria, Australia
    Pediatr Res 66:400-4. 2009
    ..We conclude that airway pressures and VT are not maintained during closed endotracheal suction with either CMV or HFOV, and choice of equipment and settings will affect the degree of interruption to ventilation...
  21. ncbi request reprint Trends in use and outcome of newborn infants treated with high frequency ventilation in Australia and New Zealand, 1996-2003
    David G Tingay
    Department of Neonatology, Royal Children s Hospital, Melbourne, Vic, Australia
    J Paediatr Child Health 43:160-6. 2007
    ..To examine the use of high frequency ventilation (HFV) to treat newborn infants in Australia and New Zealand and the associated complications and outcomes...
  22. ncbi request reprint The deflation limb of the pressure-volume relationship in infants during high-frequency ventilation
    David G Tingay
    Department of Neonatology, Royal Children s Hospital, Flemington Road, Parkville, Victoria 3052, Australia
    Am J Respir Crit Care Med 173:414-20. 2006
    ..Currently, a lack of reliable methods for assessing lung volume limits clinicians' ability to achieve the optimum volume range...
  23. ncbi request reprint Effects of tidal volume and positive end-expiratory pressure during resuscitation of very premature lambs
    Megan E Probyn
    Department of Physiology, Monash University, Melbourne, VIC 3800, Australia
    Acta Paediatr 94:1764-70. 2005
    ..Guidelines recommend neonatal resuscitation without controlling tidal volume or positive end-expiratory pressure (PEEP). However, these may improve gas exchange, lung volume and outcome...
  24. ncbi request reprint High-frequency oscillatory ventilation with low oscillatory frequency in pulmonary interstitial emphysema
    Katharine A G Squires
    Neonatal and Paediatric Intensive Care Unit, Royal Hobart Hospital, Hobart, TAS, Australia
    Neonatology 104:243-9. 2013
    ..Pulmonary interstitial emphysema (PIE) is a common respiratory illness in preterm infants associated with significant morbidity and mortality for which the ventilatory management is imperfect...
  25. ncbi request reprint Oxygen saturation targeting in preterm infants receiving continuous positive airway pressure
    Kathleen Lim
    Department of Pediatrics, Royal Hobart Hospital and University of Tasmania, Hobart, Tasmania, Australia
    J Pediatr 164:730-736.e1. 2014
    ....
  26. ncbi request reprint Pressure and flow waveform characteristics of eight high-frequency oscillators
    Edward R Harcourt
    1Neonatology, Royal Children s Hospital, Parkville, Vic, Australia 2Clinical Technology Service, Royal Children s Hospital, Parkville, Vic, Australia 3Neonatal Research, Royal Women s Hospital, Parkville, Vic, Australia 4Neonatal Research, Murdoch Children s Research Institute, Parkville, Vic, Australia 5Department of Paediatrics, Royal Hobart Hospital, Hobart, TAS, Australia 6Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano University, Milano, Italy 7Departments Paediatrics and Obstetrics and Gynaecology, University of Melbourne, Melbourne, Vic, Australia
    Pediatr Crit Care Med 15:e234-40. 2014
    ..Recently, five new oscillators have been commercially released. The objective of this study was to characterize the pressure and flow waveforms of eight commercially available oscillators...
  27. ncbi request reprint Magnetic resonance imaging in neonatal nonketotic hyperglycinemia
    Divyen K Shah
    Departments of Neonatal Medicine and Medical Imaging, Royal Children s Hospital, Flemington Road, Parkville, 3052 Victoria, Australia
    Pediatr Neurol 33:50-2. 2005
    ..The early use of combined magnetic resonance modalities in these severely affected infants helped in prognostication and clinical management...
  28. ncbi request reprint Aspiration of bile as a cause of respiratory distress in the newborn infant
    Vanessa Ellison
    Department of Neonatology, Royal Children s Hospital, Melbourne, the Department of Newborn Care, Royal Hospital for Women, Sydney, Australia
    J Pediatr 144:389-90. 2004
    ..Bile aspiration syndrome should be considered whenever there is early-onset respiratory distress in a neonate with high intestinal obstruction...
  29. ncbi request reprint Massive hepatic congenital haemangioma: clinical dilemmas
    Antonio G De Paoli
    Department of Paediatrics, Royal Hobart Hospital, and University of Tasmania, Hobart, Tasmania, Australia
    J Paediatr Child Health 43:312-4. 2007
    ..This infant died after withdrawal of neonatal intensive care support, following massive intracerebral haemorrhage. There remains considerable uncertainty regarding the classification of, and therapy for, hepatic vascular anomalies...
  30. ncbi request reprint Lung volume recruitment after surfactant administration modifies spatial distribution of ventilation
    Inez Frerichs
    Department of Anesthesiological Research, University of Gottingen, Germany
    Am J Respir Crit Care Med 174:772-9. 2006
    ..Although surfactant replacement therapy is an established treatment in infant respiratory distress syndrome, the optimum strategy for ventilatory management before, during, and after surfactant instillation remains to be elucidated...
  31. ncbi request reprint Blood gases and pulmonary blood flow during resuscitation of very preterm lambs treated with antenatal betamethasone and/or Curosurf: effect of positive end-expiratory pressure
    Kelly J Crossley
    Department of Physiology, Monash University, Clayton, Victoria 3800, Australia
    Pediatr Res 62:37-42. 2007
    ..These treatments do not alter the deleterious effects of high levels of PEEP on PBF...