Genomes and Genes


Jeff Holst


Affiliation: Centenary Institute
Country: Australia


  1. van Geldermalsen M, Quek L, Turner N, Freidman N, Pang A, Guan Y, et al. Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways. BMC Cancer. 2018;18:689 pubmed publisher
    ..Together these data showed that BenSer blockade inhibited breast cancer cell growth and viability through disruption of intracellular amino acid homeostasis and inhibition of downstream metabolic and growth pathways. ..
  2. Marshall A, van Geldermalsen M, Otte N, Anderson L, Lum T, Vellozzi M, et al. LAT1 is a putative therapeutic target in endometrioid endometrial carcinoma. Int J Cancer. 2016;139:2529-39 pubmed publisher
    ..LAT1 inhibition may offer an effective therapeutic strategy in endometrial cancer patients whose tumours exhibit high LAT1 expression. ..